Nk Cell Subsets In Health And Disease New Developments

Author : Emanuela Marcenaro,Luigi D. Notarangelo,Jordan S. Orange,Eric Vivier
Publisher : Frontiers Media SA
Page : 245 pages
File Size : 51,8 Mb
Release : 2017-11-29
Category : Electronic book
ISBN : 9782889453504

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NK Cell Subsets in Health and Disease: New Developments by Emanuela Marcenaro,Luigi D. Notarangelo,Jordan S. Orange,Eric Vivier Pdf

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 48,5 Mb
Release : 2017
Category : Electronic
ISBN : OCLC:1368410314

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NK Cell Subsets in Health and Disease: New Developments by Anonim Pdf

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.

Author : Eric Vivier,James Di Santo,Alessandro Moretta
Publisher : Springer
Page : 247 pages
File Size : 49,6 Mb
Release : 2016-02-15
Category : Medical
ISBN : 9783319239163

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Natural Killer Cells by Eric Vivier,James Di Santo,Alessandro Moretta Pdf

To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.

Author : Ewa Sitnicka,Yenan Bryceson,Aharon Freud,Emily Mace
Publisher : Frontiers Media SA
Page : 177 pages
File Size : 52,7 Mb
Release : 2020-09-02
Category : Medical
ISBN : 9782889639779

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Molecular and Cellular Pathways in NK Cell Development by Ewa Sitnicka,Yenan Bryceson,Aharon Freud,Emily Mace Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Massimo Vitale,Simona Sivori,Michael A. Caligiuri
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2020
Category : Electronic
ISBN : OCLC:1368452402

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Natural Killer Cells in Tissue Compartments by Massimo Vitale,Simona Sivori,Michael A. Caligiuri Pdf

N the last years, our knowledge of human NK cell biology has increased significantly. Several stimulating studies have provided the basis for understanding how NK cells can be "educated" to acquire immunological competence following maturation, or to adapt their function to the environmental changes of "self". New information has been acquired on their lifespan and on the persistence of memory-like NK cell subsets in response to certain viral infections. In addition, the identification and characterization of new markers and the development of more effective analytic approaches have led to the definition of various phenotypically and/or functionally-defined cell subsets. These advances have, in turn, enabled us to study NK cells beyond the peripheral blood, in different tissue compartments including the bone marrow, liver, lungs, skin, intestine and uterus. Recent data indicates that at least part of the tissue NK cell compartment consists of resident cells (which rarely recirculate) characterized by tissue-specific phenotypes and, in some cases, endowed with specialized functions related to the distinct organs in which they reside. These findings stimulate further questions (i) on the origins of these putative tissue-specific NK cell subsets; (ii) on their functional interplay with the local microenvironment; (iii) on their immunological competence and memory capacity and (iv) on their possible specific functional role in healthy and diseased tissues. In this context, the assessment of phenotype, function, maturation, education, differentiation and reprogramming of effector functions in tissue NK cells represents a new stimulating field of investigation that would help to get a more comprehensive picture of NK cell biology. In this Research Topic, we collect articles that highlight the recent advances in our understanding of tissue NK cells and that provide insight into opening new viewpoints on the role of NK cells in both health and disease.

Author : Judith Fraussen,Deborah K. Dunn-Walters,Veerle Somers,Mirjam van der Burg
Publisher : Frontiers Media SA
Page : 232 pages
File Size : 47,6 Mb
Release : 2022-03-04
Category : Medical
ISBN : 9782889745654

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New Insights Into B cell Subsets in Health and Disease by Judith Fraussen,Deborah K. Dunn-Walters,Veerle Somers,Mirjam van der Burg Pdf

Author : Jacques Zimmer
Publisher : Springer Science & Business Media
Page : 425 pages
File Size : 43,6 Mb
Release : 2010-01-12
Category : Medical
ISBN : 9783642023095

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Natural Killer Cells by Jacques Zimmer Pdf

Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.

Author : Srinivas S. Somanchi
Publisher : Methods in Molecular Biology
Page : 384 pages
File Size : 49,8 Mb
Release : 2018-05-27
Category : Medical
ISBN : 1493981161

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Natural Killer Cells: Methods and Protocols by Srinivas S. Somanchi Pdf

Author : Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 51,9 Mb
Release : 2024-04-17
Category : Medical
ISBN : 9782832548042

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New insights into innate immune cell-based immunotherapies in cancer by Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta Pdf

Author : Jonathan A. Bernstein
Publisher : Springer Nature
Page : 409 pages
File Size : 48,7 Mb
Release : 2021-01-28
Category : Medical
ISBN : 9783030571573

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Primary and Secondary Immunodeficiency by Jonathan A. Bernstein Pdf

This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

Author : Massimo Vitale,Simona Sivori,Michael A. Caligiuri
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 52,9 Mb
Release : 2020-03-24
Category : Electronic
ISBN : 9782889636129

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Natural Killer Cells in Tissue Compartments by Massimo Vitale,Simona Sivori,Michael A. Caligiuri Pdf

Author : Dominik Schneidawind,Everett Meyer
Publisher : Frontiers Media SA
Page : 157 pages
File Size : 53,9 Mb
Release : 2020-05-22
Category : Electronic
ISBN : 9782889637201

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Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation by Dominik Schneidawind,Everett Meyer Pdf

Author : Anonim
Publisher : ScholarlyEditions
Page : 275 pages
File Size : 48,9 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464995972

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Lymphocytes—Advances in Research and Application: 2012 Edition by Anonim Pdf

Lymphocytes—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Lymphocytes. The editors have built Lymphocytes—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lymphocytes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lymphocytes—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Raffaele Badolato,Silvano Sozzani
Publisher : Springer Science & Business Media
Page : 249 pages
File Size : 48,8 Mb
Release : 2006-09-05
Category : Medical
ISBN : 9783764374426

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Lymphocyte Trafficking in Health and Disease by Raffaele Badolato,Silvano Sozzani Pdf

This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.

Author : Francesco Fazi,Alessandro Rosa,Constance Ciaudo,Pavel Sumazin
Publisher : Frontiers Media SA
Page : 229 pages
File Size : 40,8 Mb
Release : 2021-11-02
Category : Science
ISBN : 9782889715718

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The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease by Francesco Fazi,Alessandro Rosa,Constance Ciaudo,Pavel Sumazin Pdf