Natural Products In Medicinal Chemistry

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Natural Products in Medicinal Chemistry

Stephen Hanessian
Natural Products in Medicinal Chemistry Book PDF

Author : Stephen Hanessian
Publisher : John Wiley & Sons
Page : 652 pages
File Size : 44,9 Mb
Release : 2013-12-18
Category : Medical
ISBN : 9783527676552

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Natural Products in Medicinal Chemistry by Stephen Hanessian Pdf

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer

Medicinal Natural Products

Paul M. Dewick
Medicinal Natural Products Book PDF

Author : Paul M. Dewick
Publisher : John Wiley & Sons
Page : 524 pages
File Size : 55,9 Mb
Release : 2002-01-03
Category : Medical
ISBN : 0471496413

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Medicinal Natural Products by Paul M. Dewick Pdf

This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.

Natural Products in Medicinal Chemistry

Stephen Hanessian
Natural Products in Medicinal Chemistry Book PDF

Author : Stephen Hanessian
Publisher : John Wiley & Sons
Page : 800 pages
File Size : 46,9 Mb
Release : 2013-12-18
Category : Medical
ISBN : 9783527676569

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Natural Products in Medicinal Chemistry by Stephen Hanessian Pdf

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer

Bioactive Natural Products

Goutam Brahmachari
Bioactive Natural Products Book PDF

Author : Goutam Brahmachari
Publisher : World Scientific
Page : 695 pages
File Size : 48,5 Mb
Release : 2012
Category : Science
ISBN : 9789814335379

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Bioactive Natural Products by Goutam Brahmachari Pdf

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Medicinal Chemistry of Bioactive Natural Products

Xiao-Tian Liang,Wei-Shuo Fang
Medicinal Chemistry of Bioactive Natural Products Book PDF

Author : Xiao-Tian Liang,Wei-Shuo Fang
Publisher : John Wiley & Sons
Page : 482 pages
File Size : 44,8 Mb
Release : 2006-03-17
Category : Science
ISBN : 9780471739333

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Medicinal Chemistry of Bioactive Natural Products by Xiao-Tian Liang,Wei-Shuo Fang Pdf

Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents. Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research. Enhanced by examples with updated research results, the discussion covers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and its analogs * The antimalarial properties of the traditional Chinese medicine, Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer's disease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIV agents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and their structurally modified mimics

Natural Products Chemistry

Raymond Cooper,George Nicola
Natural Products Chemistry Book PDF

Author : Raymond Cooper,George Nicola
Publisher : CRC Press
Page : 210 pages
File Size : 52,7 Mb
Release : 2014-07-29
Category : Medical
ISBN : 9781466567610

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Natural Products Chemistry by Raymond Cooper,George Nicola Pdf

Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry. A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry. Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.

Medicinal Natural Products

Paul M. Dewick
Medicinal Natural Products Book PDF

Author : Paul M. Dewick
Publisher : Unknown
Page : 490 pages
File Size : 50,7 Mb
Release : 1997-10-28
Category : Medical
ISBN : UOM:39015040576111

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Medicinal Natural Products by Paul M. Dewick Pdf

Medicinal Natural Products A Biosynthetic Approach Paul M Dewick Department of Pharmaceutical Sciences, University of Nottingham, UK It has been estimated that up to 70% of the world’s population is reliant on natural materials for medical treatment and in the light of the continued search for new drugs by today’s pharmaceutical industry there is currently renewed interest in pharmacologically active natural products, be they from microorganisms, animals or plants. Written for undergraduate students of pharmacy, medicinal chemistry, pharmacognosy, phytochemistry, chemistry and indeed all those with an interest in natural products, Medicinal Natural Products provides a comprehensive introduction to this subject from a biosynthetic point of view. Building on fundamental chemical principles and demonstrating a unique integration of plant, microbial and animal natural products in one volume, Paul Dewick guides the reader through a wealth of diverse natural metabolites used in medicine. Sources, production methods, use as drugs and modes of action are all covered, together with semi-synthetic derivatives and synthetic analogues developed from natural product templates. Medicinal Natural Products includes extensive use of chemical schemes with annotated mechanistic explanations and is highly cross-referenced to emphasize the links and similarities among natural products. Written in a user-friendly style, this is a stimulating textbook for today’s students, and an ideal starting point for project and dissertation work.

Natural Products Pharmacology and Phytochemicals for Health Care

Debarshi Kar Mahapatra,Cristóbal Noé Aguilar,A. K. Haghi
Natural Products Pharmacology and Phytochemicals for Health Care Book PDF

Author : Debarshi Kar Mahapatra,Cristóbal Noé Aguilar,A. K. Haghi
Publisher : Apple Academic Press
Page : 258 pages
File Size : 50,8 Mb
Release : 2021
Category : Business & Economics
ISBN : 1003057934

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Natural Products Pharmacology and Phytochemicals for Health Care by Debarshi Kar Mahapatra,Cristóbal Noé Aguilar,A. K. Haghi Pdf

"Medicinal chemistry and pharmacology are closely associated fields, and the use of natural products for their medicinal properties is ever-growing. The study of drugs from natural products and their effects on the living body are explored in this volume. The book looks into the research, discovery and characterization of the chemicals that exhibit biological effects. Providing an informative compilation of research, valuable case studies, and review of existing literature in the area, the book focuses on the ethnobotanical uses of natural products and phytochemicals for health care, including applications for diabeties, ulcers, wound healing, managing chronic alcoholism, hemorrhoidal treatment, cancer mitigation, pain management, immunotherapy, and more. The book briefly describes bioinformatics, artificial intelligence, machine learning, innovations, and societal applications. Natural Products Pharmacology and Phytochemicals for Health Care: Methods and Principles in Medicinal Chemistry provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. This volume provides new coverage of some of the latest technologies and approaches in drug discovery"--

Pharmaceutical, Medicinal and Natural Product Chemistry

P. S. Kalsi,Sangeeta Jagtap
Pharmaceutical Medicinal and Natural Product Chemistry Book PDF

Author : P. S. Kalsi,Sangeeta Jagtap
Publisher : Alpha Science International, Limited
Page : 0 pages
File Size : 53,8 Mb
Release : 2013
Category : Chemistry, Organic
ISBN : 1842655981

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Pharmaceutical, Medicinal and Natural Product Chemistry by P. S. Kalsi,Sangeeta Jagtap Pdf

The modern approach to teaching and practice of organic chemistry represents the integration of traditional principles with molecular biology. The new emphasis firmly demands the study of organic chemistry teaching from its application to biochemical aspects, drug development and pharmaceutical aspects. The proposed organizational approach of the book will build from the principles of organic chemistry for example study of functional groups metabolic reactions, functionalization reactions, applications of spectroscopy, reactions and reagents and chemistry of natural products to their integration into pharmaceutical and medicinal chemistry. The proposed book in likely to be modern, readable and an interesting blend of organic and pharmaceutical chemistry, and would be useful for graduate students of both organic and pharmaceutical chemistry. The book has four principal aims: * Explains the principles of organic chemistry using biologically important molecules * Studies the chemistry of Natural products laying emphasis on general methods of structure elucidation, structure, synthesis and biogenesis from different classes of compounds * Useful for students of pharmacy covering the organic chemistry component * To face and excel in interview/selection committee in the subject of organic and pharmaceutical chemistry

Medicinal Natural Products: A Disease-Focused Approach

Anonim
Medicinal Natural Products A Disease Focused Approach Book PDF

Author : Anonim
Publisher : Academic Press
Page : 532 pages
File Size : 45,5 Mb
Release : 2020-09-21
Category : Science
ISBN : 9780128210208

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Medicinal Natural Products: A Disease-Focused Approach by Anonim Pdf

Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition, with chapters in this new release covering Medicinal Natural Products – An Introduction, Anticancer Natural Products, Antimicrobial Natural Products, Antimalarial and Antiparasitic Natural Products, Anti-inflammatory Natural Products, Neuroprotective Natural Products, Hepatoprotective Natural Products, Nephroprotective Natural Products, Cancer Chemopreventive Natural Products, Antipsoriatic Natural Products, Medicinal Natural Products in Osteoporosis, Antidiabetic Natural Products, Anti-obesity Natural Products, and much more. Presents a disease-focused perspective Includes the latest on the medicinal chemistry of natural products Covers natural products in drug delivery

Chemistry of Natural Products

Mayuri Napagoda,Lalith Jayasinghe
Chemistry of Natural Products Book PDF

Author : Mayuri Napagoda,Lalith Jayasinghe
Publisher : Walter de Gruyter GmbH & Co KG
Page : 302 pages
File Size : 52,5 Mb
Release : 2022-04-19
Category : Science
ISBN : 9783110593655

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Chemistry of Natural Products by Mayuri Napagoda,Lalith Jayasinghe Pdf

Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.

Chemistry of Natural Products

N. R. Krishnaswamy
Chemistry of Natural Products Book PDF

Author : N. R. Krishnaswamy
Publisher : Universities Press
Page : 240 pages
File Size : 49,8 Mb
Release : 1999
Category : Biochemistry
ISBN : 8173710937

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Chemistry of Natural Products by N. R. Krishnaswamy Pdf

This book is a comprehensive account of the essential features of the chemistry of organic compounds of natural origin. The objective has been to condense the encyclopedic range of the subject into a medium-sized book by taking a radically different approach.

Studies in Natural Products Chemistry

Atta-ur-Rahman
Studies in Natural Products Chemistry Book PDF

Author : Atta-ur-Rahman
Publisher : Elsevier
Page : 460 pages
File Size : 50,8 Mb
Release : 1988
Category : Science
ISBN : 9780128179062

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Studies in Natural Products Chemistry by Atta-ur-Rahman Pdf

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII), Volume 65, is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Biologically Active Natural Products

Stephen J. Cutler,Horace G. Cutler
Biologically Active Natural Products Book PDF

Author : Stephen J. Cutler,Horace G. Cutler
Publisher : CRC Press
Page : 296 pages
File Size : 52,5 Mb
Release : 1999-07-27
Category : Medical
ISBN : 9781420048650

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Biologically Active Natural Products by Stephen J. Cutler,Horace G. Cutler Pdf

Biologically Active Natural Products: Pharmaceuticals demonstrates the connections between agrochemicals and pharmaceuticals and explores the use of plants and plant products in the formulation and development of pharmaceuticals. Experts from around the world examine a multitude of topics, including evaluation of extracts from tropical plants for p

Pharmaceutical Chemistry of Natural Products

V. Alagarsamy
Pharmaceutical Chemistry of Natural Products Book PDF

Author : V. Alagarsamy
Publisher : Elsevier India
Page : 62 pages
File Size : 54,8 Mb
Release : 2012-09-19
Category : Medical
ISBN : 9788131231340

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Pharmaceutical Chemistry of Natural Products by V. Alagarsamy Pdf

Salient Features Logical and concise presentation of content as per the needs of the students Incorporation of all chemical and pharmaceutical aspects of the natural products Systematic and consistent organization of chapters: overview, nomenclature, classification, qualitative chemical tests, and general physical and chemical properties Detailed discussion on pharmaceutically important natural products with the source, pharmacological properties and uses, along with their general properties Interesting and user-friendly presentation of pharmacological action, to help the students quickly recapitulate the action of the drug Simplified presentation of structural elucidation along with structures of compounds, which helps to reproduce well in examinations Structure-activity relationship (SAR) of some important groups of natural products, e.g. estrogens, progesterones, penicillins, etc. Comprehensive coverage of syllabi of all the major Indian universities, AICTE and the PCI