Neurobiology Of Epilepsy

Author : Ivan Soltesz,Kevin Staley
Publisher : Academic Press
Page : 624 pages
File Size : 42,8 Mb
Release : 2011-09-02
Category : Science
ISBN : 0080559530

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Computational Neuroscience in Epilepsy by Ivan Soltesz,Kevin Staley Pdf

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures Contributors are top experts at the forefront of computational epilepsy research Chapter contents are highly relevant to both basic and clinical epilepsy researchers

Author : Anonim
Publisher : Academic Press
Page : 250 pages
File Size : 52,6 Mb
Release : 2016-06-20
Category : Science
ISBN : 9780444636454

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Neurobiology of Epilepsy by Anonim Pdf

Neurobiology of Epilepsy: From Genes to Networks is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields. Explores new trends and developments in the neurobiology of Epilepsy Enhances the literature of neuroscience by further expanding the established, ongoing international series Progress in Brain Research Examines major areas of basic and clinical research within the field

Author : Jerome Engel, Jr.,Istvan Mody
Publisher : Lippincott Williams & Wilkins
Page : 1015 pages
File Size : 42,5 Mb
Release : 2022-08-30
Category : Medical
ISBN : 9781975194222

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Neurobiology of the Epilepsies by Jerome Engel, Jr.,Istvan Mody Pdf

Neurobiology of the Epilepsies – From Epilepsy: A Comprehensive Textbook, 3rd Edition, provides a concise, up-to-date review of basic sciences and the latest research advances in epilepsy. Ideal for general neurologists and neurosurgeons, epilepsy/clinical neurophysiology specialists, basic scientists, clinical researchers, and other health care providers with an interest in epilepsy, this new volume by Drs. Istvan Mody, Hal Blumenfeld, Jerome Engel, Jr., Asla Ptkänen, Ivan Soltesz, and Annamaria Vezzani offers comprehensive, authoritative coverage of this critical and complex area of the field.

Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 53,7 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545

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Jasper's Basic Mechanisms of the Epilepsies by Jeffrey L. Noebels,Massimo Avoli Pdf

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : Shirley Ferguson
Publisher : Elsevier
Page : 168 pages
File Size : 47,8 Mb
Release : 2006-12-01
Category : Medical
ISBN : 9780080469171

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Temporal Lobe Epilepsy and the Mind-Brain Relationship: A New Perspective by Shirley Ferguson Pdf

This book is devoted to the surgical treatment of epilepsy and its consequences, and provides an extraordinary perspective on the fascinating question of the relationship between brain and mind. Contrary to the current emphasis on statistics and objectivity, this book is dedicated to understanding the whole person, the life and experiences of the individual. It reports on cutting-edge technical skills provided with a human touch. This book reflects the understanding that the temporolimbic seizure originates in tissue providing the substrate for the emotional life and memory. Finally, it emphasizes the value of clinical research – here, conducted in the course of the diagnosis and surgical treatment of epilepsy – in helping to elucidate the relationship between brain and mind.

Author : R. Eugene Ramsay
Publisher : Elsevier
Page : 368 pages
File Size : 53,7 Mb
Release : 2007-04-16
Category : Science
ISBN : 9780080489254

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Neurobiology of Epilepsy and Aging by R. Eugene Ramsay Pdf

This volume in the International Review of Neurobiology series addresses the epidemiology, pathophysiology, and treatment of epilepsy in elderly patients. Demographically, the elderly comprise both the fastest-growing segment of the U.S. population and the adult age group with the highest incidence of epilepsy, yet there are relatively few publications devoted to this clinical subgroup. The intersection of these two complex processes—epilepsy and advancing age—will have an increasing impact on medical and community care. The etiology, prognosis, and differential diagnosis of epilepsy can all be affected by the normal aging process and by the frequent comorbidities encountered in an elderly population. Chapters in this book review the effects of aging on brain function and on drug metabolism and interactions, covering the gamut of research from animal models of aging and epilepsy to clinical trials and outcomes. Topics also include the dangers of misdiagnosing status epilepticus, the special issues encountered in recruiting and retaining elderly clinical trial participants, and the use of antiepileptic drugs in the elderly. In both the clinic and the research laboratory, a better understanding of how epilepsy may differ between younger and older patients will be valuable in determining the best possible care for geriatric patients with epilepsy.

Author : Jerome Engel Jr
Publisher : Oxford University Press
Page : 737 pages
File Size : 52,5 Mb
Release : 2013-01-31
Category : Medical
ISBN : 9780195328547

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Seizures and Epilepsy by Jerome Engel Jr Pdf

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Author : Devin K. Binder,Helen E. Scharfman
Publisher : Springer Science & Business Media
Page : 265 pages
File Size : 49,5 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9781475763768

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Recent Advances in Epilepsy Research by Devin K. Binder,Helen E. Scharfman Pdf

Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented in vitro and in vivo electrophysiologic and phenotypic characterization. Recent Advances in Epilepsy Research sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epilepsy, malformations of cortical development, neurogenesis, new animal models of epilepsy and the use of brain stimulation to treat epilepsy. This book should be of interest to a wide variety of audiences, including graduate students in neurobiology and related disciplines, neuroscientists, medical students, neurologists, neurosurgeons, and industry including pharmaceutical companies and medical device companies. There are many ideas in this book that will lead ingenious innovators in academia and industry to develop new and better therapies.

Author : Samden Lhatoo
Publisher : Oxford University Press
Page : 395 pages
File Size : 47,6 Mb
Release : 2013
Category : Medical
ISBN : 9780199659043

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Oxford Textbook of Epilepsy and Epileptic Seizures by Samden Lhatoo Pdf

Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

Author : Anonim
Publisher : Elsevier
Page : 364 pages
File Size : 40,5 Mb
Release : 2014-07-24
Category : Science
ISBN : 9780124199576

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Modern Concepts of Focal Epileptic Networks by Anonim Pdf

This volume of International Review of Neurobiology concentrates on modern concepts of focal epileptic networks. The volume addresses specific topics such as seizures (including transition and termination), limbic networks, alteration of metabolism, and neocortical focus and malformation of cortical development, among others. Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews, and thematic volumes that focus on recent progress in a specific area of neurobiology research. Our knowledge about the mechanisms involved in pathophysiology of epilepsy has rapidly expanded during last decade This special volume brings overview about modern concepts of epileptic focus organization and about the altered neural network dynamics which results in propensity of the brain tissue to generate spontaneous and repeated seizures

Author : Jerome Engel, Jr.
Publisher : Oxford University Press
Page : 128 pages
File Size : 41,5 Mb
Release : 2012-12-31
Category : Medical
ISBN : 9780199370559

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Seizures and Epilepsy by Jerome Engel, Jr. Pdf

This second edition of Seizures and Epilepsy, written almost a quarter of a century after the ground-breaking first edition, is more than an update: it is a complete revision due to tremendous advances in the field. Our understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. According to the World Health Organization, epilepsy accounts for 1% of the global burden of disease, equivalent to breast cancer in women and lung cancer in men. Among primary disorders of the brain, it is equivalent to depression, dementia, and substance abuse. Singly authored by Jerome Engel, Jr, this must-read from 1989 reasserts itself as a modern classic comprehensive textbook covering a broad range of both basic and clinical epileptology. Basic scientists who are interested in learning more about clinical epileptology, as well as clinicians who would like to understand more about fundamental mechanisms will find this text useful. Residents and postdoctoral fellows, particularly those interested in a career in epilepsy, will benefit from the continuity and organization of this single-authored comprehensive textbook.

Author : Gregory D. Cascino,Joseph I. Sirven,William O. Tatum
Publisher : John Wiley & Sons
Page : 550 pages
File Size : 54,6 Mb
Release : 2021-08-02
Category : Medical
ISBN : 9781119431824

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Epilepsy by Gregory D. Cascino,Joseph I. Sirven,William O. Tatum Pdf

Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

Author : J. Kiffin Penry
Publisher : Unknown
Page : 128 pages
File Size : 50,6 Mb
Release : 1978
Category : Epilepsy
ISBN : LCCN:79601844

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Indexes to the Epilepsy Accessions of the Epilepsy Information System by J. Kiffin Penry Pdf

Author : R. Eugene Ramsay,Ilo E.. Leppik,Nancy L.. Nadon
Publisher : Unknown
Page : 0 pages
File Size : 55,5 Mb
Release : 2007
Category : Electronic
ISBN : OCLC:1226654773

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The Neurobiology of Epilepsy and Aging by R. Eugene Ramsay,Ilo E.. Leppik,Nancy L.. Nadon Pdf

Author : Suzanne O'Sullivan
Publisher : Random House
Page : 352 pages
File Size : 49,7 Mb
Release : 2018-04-05
Category : Medical
ISBN : 9781473546769

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Brainstorm by Suzanne O'Sullivan Pdf

'I loved it. She is in my view the best science writer around - a true descendant of Oliver Sacks' Sathnam Sanghera, author of The Boy with the Topknot The brain is the most complex structure in the universe. In Brainstorm the Wellcome Prize-winning author of It’s All in Your Head uncovers the most eye-opening symptoms medicine has to offer. ‘Powerfully life-affirming... Brainstorm is testament to O'Sullivan's unshowy clarity of thought and her continued marvelling at the mysteries of the brain’ Guardian Brainstorm examines the stories of people whose symptoms are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a teenager who one day arrives home with inexplicably torn clothes; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe, and neurologists must puzzle out life-changing diagnoses from the tiniest of clues – it’s the ultimate in medical detective work. In this riveting book, one of the UK’s leading neurologists takes you with her as she follows the trail of her patients’ symptoms: feelings of déjà vu lead us to a damaged hippocampus; spitting and fidgeting to the right temporal lobe; fear of movement to a brain tumour; a missed heart beat to the limbic system. It’s a journey that will open your eyes to the unfathomable intricacies of the brain, and the infinite variety of human capacity and experience.