Download Full eBooks in PDF
Neuroinflammation And Its Resolution From Molecular Mechanisms To Therapeutic Perspectives Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Neuroinflammation And Its Resolution From Molecular Mechanisms To Therapeutic Perspectives book. This book definitely worth reading, it is an incredibly well-written.
Author : Morena Zusso,Stefano Moro,Pietro Giusti,Leanne Stokes
Publisher : Frontiers Media SA
Page : 282 pages
File Size : 55,5 Mb
Release : 2020-07-14
Category : Electronic
ISBN : 9782889638543
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Page : 334 pages
File Size : 53,5 Mb
Release : 2021-09-15
Category : Medical
ISBN : 9780323884617
Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects. Discusses the molecular aspects of neuroinflammation, resolution and neuroprotection Examines the role of diet and exercise on neuroinflammatory diseases Provides cutting-edge research on signal transduction processes Explores the treatment of neurological disorders caused by neuroinflammation
Author : Ole Köhler-Forsberg,Belinda Lennox,Norbert Müller
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 50,7 Mb
Release : 2020-12-23
Category : Medical
ISBN : 9782889662692
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Anonim
Publisher : Academic Press
Page : 294 pages
File Size : 47,5 Mb
Release : 2018-11-24
Category : Medical
ISBN : 9780128138335
Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application
Author : Chengjin Gao,Shuming Pan,Kun Xiong
Publisher : Frontiers Media SA
Page : 355 pages
File Size : 48,6 Mb
Release : 2024-03-19
Category : Medical
ISBN : 9782832546529
The systemic inflammatory response is evident in inflammatory diseases, and the immune system secretes many cytokines involved, resulting in a robust immune response. For example, the pathogenesis of sepsis includes abnormal immune cell activation in the early stages as well as sepsis-related immunosuppression. During the immunosuppressive phase, CD4+ T cells, CD8+ T cells, Th17 cells, and γδ T cells are reduced while regulatory T cells increase. At the same time, T lymphocytes and neutrophils, as immune effector cells, interact with each other and play a key role in regulating the immune response to immune-inflammatory diseases. The increased release of neutrophil extracellular trap networks (NETs) by neutrophils leads to a significant upregulation of NETs-DNA-MPO, which further aggravates the septic inflammatory response and organ functional impairment. Therefore, it is important to deeply investigate the characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, and targeting therapies against them may provide new ideas for the precise treatment of diseases.
Author : Royal Society of South Australia
Publisher : Unknown
Page : 308 pages
File Size : 55,8 Mb
Release : 1963
Category : Science
ISBN : UVA:X001747338
Author : Katalin Lumniczky,Serge M. Candéias,Udo S. Gaipl,Benjamin Frey
Publisher : Frontiers Media SA
Page : 283 pages
File Size : 53,7 Mb
Release : 2018-05-03
Category : Electronic
ISBN : 9782889454747
For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.
Author : Akhlaq A Farooqui
Publisher : Springer
Page : 402 pages
File Size : 50,8 Mb
Release : 2016-03-05
Category : Medical
ISBN : 9783319158891
This is the first book on the market that explores the importance of curcumin for the treatment of neurological disorders. It has been estimated that 35.6 million people globally had dementia in 2010 and the prevalence of dementia has been predicted to double every 20 years. Thus, 115.4 million people may be living with dementia in 2050. Alzheimer’s disease (AD) is the leading cause of dementia and is present in 60%–70% of people with dementia. Unless new discoveries are made in the prevention or treatment of AD, the number of cases in the US alone is estimated to increase threefold, to 13.2 million by the year 2050. Thus, it is important to focus on delaying and treating the onset of AD by curcumin may be an important step for controlling AD. Regular consumption of healthy diet containing curcumin enriched foods, moderate exercise, and regular sleep may produce beneficial effects not only on motor and cognitive functions, but also on memory deficits that occur to some extent during normal aging and to a large extent in AD. Delaying the onset and progression of AD and improving its symptoms by few years with regular consumption of curcumin may relieve some of the burden on health care systems. In service of this goal, this volume gives readers a comprehensive and cutting edge description of the importance of curcumin for the treatment of AD in cell culture and animal models in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. It can be used as supplement text for a range of neuroscience and nutrition courses. Clinicians, neuroscientists, neurologists and pharmacologists will find this book useful for understanding molecular aspects of AD treatment by curcumin.
Author : Adriano Rossi,Deborah A. Sawatzky
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 44,5 Mb
Release : 2008-03-17
Category : Medical
ISBN : 9783764375065
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Author : Gonzalo Emiliano Aranda Abreu
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 53,7 Mb
Release : 2017-08-23
Category : Medical
ISBN : 9789535134510
"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.
Author : Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta
Publisher : Springer
Page : 489 pages
File Size : 50,9 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9783034808378
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author : Tuan Leng Tay,Giuseppe Locatelli,Gabriela Constantin,V. Wee Yong
Publisher : Frontiers Media SA
Page : 259 pages
File Size : 44,7 Mb
Release : 2022-05-03
Category : Medical
ISBN : 9782889760701
Author : Suman Dutta,Miriam Sklerov,Charlotte Elisabeth Teunissen,Gal Bitan
Publisher : Frontiers Media SA
Page : 273 pages
File Size : 46,6 Mb
Release : 2023-03-23
Category : Science
ISBN : 9782832518007
Author : Nesrine Salah El Dine El Sayed,Riham Salah El Dine,Jolanta Kotlinska,Barbara Budzynska,Anna Boguszewska-Czubara
Publisher : Frontiers Media SA
Page : 270 pages
File Size : 46,8 Mb
Release : 2023-04-14
Category : Science
ISBN : 9782832506615
Author : Honorio Benzon,James P. Rathmell,Christopher L. Wu,Dennis Turk,Charles E. Argoff,Robert W Hurley
Publisher : Elsevier Health Sciences
Page : 1520 pages
File Size : 43,5 Mb
Release : 2022-02-10
Category : Medical
ISBN : 9780323711029
For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. Includes the latest guidelines on facet injections and safety of contrast agents. Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions.
