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Author : John David Griffiths,Kelly Shen,Padraig Gleeson
Publisher : Frontiers Media SA
Page : 216 pages
File Size : 50,5 Mb
Release : 2022-11-10
Category : Science
ISBN : 9782832501795
Author : Michele Giugliano,Mario Negrello,Daniele Linaro
Publisher : Springer Nature
Page : 361 pages
File Size : 46,5 Mb
Release : 2022-04-26
Category : Medical
ISBN : 9783030894399
This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Christof Koch,Idan Segev
Publisher : MIT Press
Page : 700 pages
File Size : 55,8 Mb
Release : 1998
Category : Nervous system
ISBN : 0262112310
Kinetic Models of Synaptic Transmission / Alain Destexhe, Zachary F. Mainen, Terrence J. Sejnowski / - Cable Theory for Dendritic Neurons / Wilfrid Rall, Hagai Agmon-Snir / - Compartmental Models of Complex Neurons / Idan Segev, Robert E. Burke / - Multiple Channels and Calcium Dynamics / Walter M. Yamada, Christof Koch, Paul R. Adams / - Modeling Active Dendritic Processes in Pyramidal Neurons / Zachary F. Mainen, Terrence J. Sejnowski / - Calcium Dynamics in Large Neuronal Models / Erik De Schutter, Paul Smolen / - Analysis of Neural Excitability and Oscillations / John Rinzel, Bard Ermentrout / - Design and Fabrication of Analog VLSI Neurons / Rodney Douglas, Misha Mahowald / - Principles of Spike Train Analysis / Fabrizio Gabbiani, Christof Koch / - Modeling Small Networks / Larry Abbott, Eve Marder / - Spatial and Temporal Processing in Central Auditory Networks / Shihab Shamma / - Simulating Large Networks of Neurons / Alexander D. Protopapas, Michael Vanier, James M. Bower / ...
Author : Vassilis Cutsuridis
Publisher : Springer Nature
Page : 222 pages
File Size : 44,6 Mb
Release : 2019-10-11
Category : Medical
ISBN : 9783030188306
This book focuses on our current understanding of brain dynamics in various brain disorders (e.g. epilepsy, Alzheimer’s and Parkinson’s disease) and how the multi-scale, multi-level tools of computational neuroscience can enhance this understanding. In recent years, there have been significant advances in the study of the dynamics of the disordered brain at both the microscopic and the macroscopic levels. This understanding can be furthered by the application of multi-scale computational models as integrative principles that may link single neuron dynamics and the dynamics of local and distant brain regions observed using human EEG, ERPs, MEG, LFPs and fMRI. Focusing on the computational models that are used to study movement, memory and cognitive disorders as well as epilepsy and consciousness related diseases, the book brings together physiologists and anatomists investigating cortical circuits; cognitive neuroscientists studying brain dynamics and behavior by means of EEG and functional magnetic resonance imaging (fMRI); and computational neuroscientists using neural modeling techniques to explore local and large-scale disordered brain dynamics. Covering topics that have a significant impact on the field of medicine, neuroscience and computer science, the book appeals to a diverse group of investigators.
Author : Christof Koch
Publisher : MIT Press (MA)
Page : 524 pages
File Size : 51,9 Mb
Release : 1989-01
Category : Psychology
ISBN : 0262111330
Methods in Neuronal Modeling is the first technical handbook on computational neuroscience. Written for researchers and theoreticians alike, it outlines methods and techniques used for simulating on digital computers the functional properties of single neurons from synapses, dendrites, single cells; and small invertebrate networks to large scale neural networks in the mammalian nervous system. The use of new experimental tools such as selective staining methods, membrane patch electrodes, voltage and calcium-dependent dyes, and multielectrode recordings, together with the, advent of universally available powerful computing, makes it possible to construct detailed and realistic models of neuronal systems. Methods in Neuronal Modeling addresses such questions as what can and should be simulated and what techniques should be used; what experimental parameters are crucial for such simulations, and whether these models may be verified experimentally. Chapters cover simulation of passive dendritic trees, compartmental models of single cells including neurons with a number of different ionic channels, calcium current dynamics, simulations of small invertebrate networks, simulations of the mammalian cortex, connectionists' models, and the use of parallel computers in modeling neural networks. Although the chapters were written by several authors, they are uniform in structure and notation. Detailed examples are given to clarify the different approaches. Each chapter concludes with a description of the model discussed and the details of its implementation on the computer. Christof Koch is an Assistant Professor of Computation and Neural Systems at the California Institute of Technology. Idan Segev is a Lecturer in Neurobiology at the Institute of Life Science, Hebrew University of Jerusalem. Methods in Neuronal Modeling inaugurates the new series in Computational Neuroscience, edited by Terrence J. Sejnowski and Tomaso Poggio. A Bradford Book.
Author : Markus Butz,Wolfram Schenck,Arjen van Ooyen
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 51,8 Mb
Release : 2017-01-05
Category : Electronic book
ISBN : 9782889450657
Supercomputing facilities are becoming increasingly available for simulating activity dynamics in large-scale neuronal networks. On today's most advanced supercomputers, networks with up to a billion of neurons can be readily simulated. However, building biologically realistic, full-scale brain models requires more than just a huge number of neurons. In addition to network size, the detailed local and global anatomy of neuronal connections is of crucial importance. Moreover, anatomical connectivity is not fixed, but can rewire throughout life (structural plasticity)—an aspect that is missing in most current network models, in which plasticity is confined to changes in synaptic strength (synaptic plasticity). The papers in this Ebook, which may broadly be divided into three themes, aim to bring together high-performance computing with recent experimental and computational research in neuroanatomy. In the first theme (fiber connectivity), new methods are described for measuring and data-basing microscopic and macroscopic connectivity. In the second theme (structural plasticity), novel models are introduced that incorporate morphological plasticity and rewiring of anatomical connections. In the third theme (large-scale simulations), simulations of large-scale neuronal networks are presented with an emphasis on anatomical detail and plasticity mechanisms. Together, the articles in this Ebook make the reader aware of the methods and models by which large-scale brain networks running on supercomputers can be extended to include anatomical detail and plasticity.
Author : Christof Koch,Joel L. Davis
Publisher : MIT Press
Page : 376 pages
File Size : 45,7 Mb
Release : 1994
Category : Mathematics
ISBN : 0262111837
This book originated at a small and informal workshop held in December of 1992 in Idyllwild, a relatively secluded resort village situated amid forests in the San Jacinto Mountains above Palm Springs in Southern California. Eighteen colleagues from a broad range of disciplines, including biophysics, electrophysiology, neuroanatomy, psychophysics, clinical studies, mathematics and computer vision, discussed 'Large Scale Models of the Brain, ' that is, theories and models that cover a broad range of phenomena, including early and late vision, various memory systems, selective attention, and the neuronal code underlying figure-ground segregation and awareness (for a brief summary of this meeting, see Stevens 1993). The bias in the selection of the speakers toward researchers in the area of visual perception reflects both the academic background of one of the organizers as well as the (relative) more mature status of vision compared with other modalities. This should not be surprising given the emphasis we humans place on'seeing' for orienting ourselves, as well as the intense scrutiny visual processes have received due to their obvious usefullness in military, industrial, and robotic applications. JMD.
Author : Chris Eliasmith,Charles H. Anderson
Publisher : MIT Press
Page : 384 pages
File Size : 40,5 Mb
Release : 2003
Category : Bioinformatics
ISBN : 0262550601
A synthesis of current approaches to adapting engineering tools to the study of neurobiological systems.
Author : Chris Eliasmith
Publisher : Oxford University Press
Page : 475 pages
File Size : 51,9 Mb
Release : 2013-04-16
Category : Psychology
ISBN : 9780199794690
How to Build a Brain provides a detailed exploration of a new cognitive architecture - the Semantic Pointer Architecture - that takes biological detail seriously, while addressing cognitive phenomena. Topics ranging from semantics and syntax, to neural coding and spike-timing-dependent plasticity are integrated to develop the world's largest functional brain model.
Author : Alan Anticevic,John D Murray
Publisher : Academic Press
Page : 332 pages
File Size : 49,7 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9780128098264
Computational Psychiatry: Mathematical Modeling of Mental Illness is the first systematic effort to bring together leading scholars in the fields of psychiatry and computational neuroscience who have conducted the most impactful research and scholarship in this area. It includes an introduction outlining the challenges and opportunities facing the field of psychiatry that is followed by a detailed treatment of computational methods used in the service of understanding neuropsychiatric symptoms, improving diagnosis and guiding treatments. This book provides a vital resource for the clinical neuroscience community with an in-depth treatment of various computational neuroscience approaches geared towards understanding psychiatric phenomena. Its most valuable feature is a comprehensive survey of work from leaders in this field. Offers an in-depth overview of the rapidly evolving field of computational psychiatry Written for academics, researchers, advanced students and clinicians in the fields of computational neuroscience, clinical neuroscience, psychiatry, clinical psychology, neurology and cognitive neuroscience Provides a comprehensive survey of work from leaders in this field and a presentation of a range of computational psychiatry methods and approaches geared towards a broad array of psychiatric problems
Author : Katrin Amunts,Lucio Grandinetti,Thomas Lippert,Nicolai Petkov
Publisher : Springer Nature
Page : 159 pages
File Size : 45,5 Mb
Release : 2021-07-20
Category : Computers
ISBN : 9783030824273
This open access book constitutes revised selected papers from the 4th International Workshop on Brain-Inspired Computing, BrainComp 2019, held in Cetraro, Italy, in July 2019. The 11 papers presented in this volume were carefully reviewed and selected for inclusion in this book. They deal with research on brain atlasing, multi-scale models and simulation, HPC and data infra-structures for neuroscience as well as artificial and natural neural architectures.
Author : Mikhail I. Rabinovich,Karl J. Friston,Pablo Varona
Publisher : MIT Press
Page : 371 pages
File Size : 54,6 Mb
Release : 2023-12-05
Category : Medical
ISBN : 9780262549905
Experimental and theoretical approaches to global brain dynamics that draw on the latest research in the field. The consideration of time or dynamics is fundamental for all aspects of mental activity—perception, cognition, and emotion—because the main feature of brain activity is the continuous change of the underlying brain states even in a constant environment. The application of nonlinear dynamics to the study of brain activity began to flourish in the 1990s when combined with empirical observations from modern morphological and physiological observations. This book offers perspectives on brain dynamics that draw on the latest advances in research in the field. It includes contributions from both theoreticians and experimentalists, offering an eclectic treatment of fundamental issues. Topics addressed range from experimental and computational approaches to transient brain dynamics to the free-energy principle as a global brain theory. The book concludes with a short but rigorous guide to modern nonlinear dynamics and their application to neural dynamics.
Author : Sergey N. Makarov
Publisher : Springer Nature
Page : 395 pages
File Size : 44,9 Mb
Release : 2021
Category : Biomedical engineering
ISBN : 9783030456238
The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
Author : F. Moss,S. Gielen
Publisher : Gulf Professional Publishing
Page : 1080 pages
File Size : 41,8 Mb
Release : 2001-06-26
Category : Mathematics
ISBN : 9780080537429
How do sensory neurons transmit information about environmental stimuli to the central nervous system? How do networks of neurons in the CNS decode that information, thus leading to perception and consciousness? These questions are among the oldest in neuroscience. Quite recently, new approaches to exploration of these questions have arisen, often from interdisciplinary approaches combining traditional computational neuroscience with dynamical systems theory, including nonlinear dynamics and stochastic processes. In this volume in two sections a selection of contributions about these topics from a collection of well-known authors is presented. One section focuses on computational aspects from single neurons to networks with a major emphasis on the latter. The second section highlights some insights that have recently developed out of the nonlinear systems approach.
Author : David Sterratt,Bruce Graham,Andrew Gillies,Gaute Einevoll,David Willshaw
Publisher : Cambridge University Press
Page : 553 pages
File Size : 50,5 Mb
Release : 2023-10-05
Category : Science
ISBN : 9781108483148
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.