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Author : KOOB,LEWIS,MEYER,PAUL
Publisher : Springer Science & Business Media
Page : 279 pages
File Size : 52,8 Mb
Release : 2013-04-18
Category : Medical
ISBN : 9781475713053
Author : Kathleen A. Grant,David M. Lovinger
Publisher : Springer
Page : 625 pages
File Size : 54,8 Mb
Release : 2019-03-27
Category : Medical
ISBN : 9783319965239
This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.
Author : Richard A. Deitrich,V. Gene Erwin
Publisher : CRC Press
Page : 482 pages
File Size : 53,8 Mb
Release : 1995-12-21
Category : Medical
ISBN : 0849383897
This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.
Author : Henri Begleiter,Benjamin Kissin
Publisher : Oxford University Press, USA
Page : 544 pages
File Size : 50,6 Mb
Release : 1996
Category : Alcohol
ISBN : 0195100948
This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
Author : Koob,Andrew Lewis,Tim Meyer
Publisher : Unknown
Page : 284 pages
File Size : 55,5 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1475713061
Author : Anonim
Publisher : Unknown
Page : 776 pages
File Size : 49,7 Mb
Release : 1989
Category : Medicine
ISBN : UOM:39015014022589
Author : Anonim
Publisher : Unknown
Page : 1064 pages
File Size : 49,6 Mb
Release : 1992
Category : Medicine
ISBN : MINN:31951P00216728F
Author : Antonius M. VanDongen
Publisher : CRC Press
Page : 368 pages
File Size : 54,9 Mb
Release : 2008-10-29
Category : Medical
ISBN : 9781420044157
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Author : Anonim
Publisher : Unknown
Page : 968 pages
File Size : 53,9 Mb
Release : 1989
Category : Medicine
ISBN : MINN:31951P00184040S
Author : Anonim
Publisher : Unknown
Page : 1398 pages
File Size : 41,9 Mb
Release : 1987
Category : Medicine
ISBN : STANFORD:36105021766048
Author : Marc Galanter
Publisher : Unknown
Page : 0 pages
File Size : 49,9 Mb
Release : 1985
Category : Electronic
ISBN : OCLC:1371646264
Author : Marc Galanter
Publisher : Springer Science & Business Media
Page : 469 pages
File Size : 49,8 Mb
Release : 2013-11-22
Category : Medical
ISBN : 9781489916846
From the President of the Research Society on Alcoholism In recent years, increasingly convincing evidence in support of a biobehavioral conceptual model of the etiology of alcoholism has emerged. In this model, the disorder is perceived as arising from the interaction of geneticlbiological vulnerability and psychosocial risk. Drinking, or alcohol-seeking, is a metric trait. Alcoholism, which is a state of abnormally intense alcohol-seeking be havior that, over time, leads to the alcohol dependence syndrome, lies at the extreme, high end of this quantitative measure. Metric traits are influenced by multiple genes; the extent of genetic loading of biological risk for alcoholism would be different in different individuals. Added to this kind of variability is the wide range of options for exposure to the psychosocial risk factors of heavy drinking provided by modern society. Further, environmental prov ocation also changes when life events change. It is not surprising, therefore, from the combination of the kinds of genetic and environmental variability described above that there is a wide array of patterns of expression of the disorder alcoholism, referred to by some as "alcoholisms. " In the search for understanding of underlying mechanisms and rational bases for potential therapy, it is important to focus our attention on the final common pathway of this disorder, alcohol-seeking behavior. This series, ever since its beginning in 1983, has been sensitive to the complexities of the interaction between biological and psychosocial risk factors in alcoholism.
Author : B. Jansson,H. Jörnvall,U. Rydberg,L. Terenius,B.L. Vallee
Publisher : Birkhäuser
Page : 402 pages
File Size : 50,7 Mb
Release : 2013-03-13
Category : Science
ISBN : 9783034873307
The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment. The aim is to integrate pertinent information from the fields of molecular and cell biology with view to establishing a molecular basis of alcohol use and abuse. An initial preview summarizes historical aspects of alcohol use, and subsequent chapters concern novel drugs, pharmacological aspects, gene structures, cloning, and enzymatic properties. Also contributions by "non-traditional" alcohol scientists have been included in this collection, in order to highlight possible interaction and parallels between different fields. Novel results of particular interest include up-dated summaries on receptors, enzymes, and other proteins, as well as corresponding gene structures and regulation, setting the basis for distinguishing markers and pinpointing further possible pharmacological treatments.
Author : William Butynski
Publisher : Unknown
Page : 114 pages
File Size : 55,5 Mb
Release : 1985
Category : Alcoholics
ISBN : UOM:39015029206268
"Provides an overview of 93 separate national organizations whose primary purpose relates to alcohol, its use and/or abuse." Sources were usually agencies themselves. Alphabetical arrangement by agencies. Entries give address, telephone number, contact person, date of founding, membership, staff, and narrative description. Index by categories of agencies.
Author : Bankole Johnson
Publisher : Elsevier Health Sciences
Page : 1146 pages
File Size : 45,8 Mb
Release : 2019-12-12
Category : Medical
ISBN : 9780323680530
Integrating scientific knowledge with today’s most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment. Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment. Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions. Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics. Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders. Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines. Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals. Includes contributions from expert international authors, making this a truly global reference to addiction medicine.