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New Research on Street Drugs by Spencer M. Cole Pdf
The word "substance" can refer to a drug of abuse, a medication or a toxin. "Polysubstance" Abuse/Dependence means that a person abuses or depends upon more than one substance, with one usually being that person's favorite or "drug of choice." It is important to note that we are not only referring to illegal drugs; over the counter or prescription drugs are often abused as well. The more commonly abused drugs today are cocaine, marijuana, inhalants and heroin. Substance exposure that can cause substance related disorders include heavy metals (e.g., lead, rat poison containing strychnine, certain pesticides, nerve gas, antifreeze, carbon dioxide and carbon monoxide). The medications, both prescriptive and over the counter, that may cause substance related disorders include anesthetics, analgesics, anticonvulsants, antihistamines, blood pressure and heart medication and muscle relaxants. This new and important book presents state-of-the-art research in this field.
A four-year investigation into the world of synthetic drugs—from black market factories to users & dealers to harm reduction activists—and what it revealed. A deeply human story, Fentanyl, Inc. is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. “A whole new crop of chemicals is radically changing the recreational drug landscape,” writes Ben Westhoff. “These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs” —and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice—and those with arcane acronyms like 25i-NBOMe—were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs’ effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China’s vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the United States and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many. “Timely and agonizing. . . . An impressive work of investigative journalism.” —USA Today “Westhoff explores the many-tentacled world of illicit opioids, from the streets of East St. Louis to Chinese pharmaceutical companies, from music festivals deep in the Michigan woods to sanctioned ‘shooting up rooms’ in Barcelona, in this frank, insightful, and occasionally searing exposé. . . . Westhoff’s well-reported and researched work will likely open eyes, slow knee-jerk responses, and start much needed conversations.” —Publishers Weekly “Our 25 Favorite Books of 2019” —St. Louis Post-Dispatch “Best Books of 2019” —Buzzfeed “Best Nonfiction of 2019” —Kirkus Reviews “50 Best Books of 2019” —Daily Telegraph “Best Nonfiction Books of 2019” —Tyler Cowen “Best Books of 2019” —Yahoo Finance
Learn the public health implications of shifting drug-related risks among the inner city poor Inner city drug use behavior shifts and changes, leaving past drug treatment programs, drug prevention efforts, health care provisions for drug users, and social service practice unprepared to effectively respond. New Drugs on the Street: Changing Inner City Patterns of Illicit Consumption tackles this problem by presenting the latest ethnographic and epidemiological studies of emerging and changing drug use behaviors in the inner city. This one-of-a-kind resource provides the latest research to help readers reconceptualize ways to think about today’s drug use to more effectively address the growing problem. Unless public health and social service professionals keep in step with the shifting patterns of drug behaviors, drug use epidemics will inevitably unfold. New Drugs on the Street reveals the latest drug use practices of the poor in the inner city, with a concentration on the research in African-American and Latino populations. Each chapter gives an in-depth look at the use of various psychotropic drugs most recently gaining popularity, along with the surprising reemergence of PCP. The rampant use of ecstasy in the rave scene is explored, along with the effects of its heavy use, its after-effects, the likelihood of poly-drug mixing, and dangerous sex risk behaviors. Urban youth drug networking is examined in detail. The alarming use of embalming fluid mixtures is discussed, along with the disturbing public health implications of its use. The illicit use of narcotics analgesics (NA) like Vicodin and other pain killers is also explored, including the unclear association between NA use and Hepatitis C. A final chapter presents the latest information on Haitian youth and young adults in Miami, Florida, with ethnographic background to illustrate the reasons for drug use in this and other ethnic minorities. This valuable source is extensively referenced and includes several helpful tables to clarify research data. New Drugs on the Street examines: ecstasy diverted pharmaceutical painkillers PCP embalming fluid narcotics analgesics (NA) drug use dynamics the changing street drug scene new drug combinations new drug-involved populations New Drugs on the Street reveals the nature and direction of the latest drug use and is essential reading for health professionals in the health social sciences, public health, nursing, and substance abuse fields that deal with low income, ethnic minority, and inner city populations.
Learn the public health implications of shifting drug-related risks among the inner city poor Inner city drug use behavior shifts and changes, leaving past drug treatment programs, drug prevention efforts, health care provisions for drug users, and social service practice unprepared to effectively respond. New Drugs on the Street: Changing Inner City Patterns of Illicit Consumption tackles this problem by presenting the latest ethnographic and epidemiological studies of emerging and changing drug use behaviors in the inner city. This one-of-a-kind resource provides the latest research to help readers reconceptualize ways to think about today’s drug use to more effectively address the growing problem. Unless public health and social service professionals keep in step with the shifting patterns of drug behaviors, drug use epidemics will inevitably unfold. New Drugs on the Street reveals the latest drug use practices of the poor in the inner city, with a concentration on the research in African-American and Latino populations. Each chapter gives an in-depth look at the use of various psychotropic drugs most recently gaining popularity, along with the surprising reemergence of PCP. The rampant use of ecstasy in the rave scene is explored, along with the effects of its heavy use, its after-effects, the likelihood of poly-drug mixing, and dangerous sex risk behaviors. Urban youth drug networking is examined in detail. The alarming use of embalming fluid mixtures is discussed, along with the disturbing public health implications of its use. The illicit use of narcotics analgesics (NA) like Vicodin and other pain killers is also explored, including the unclear association between NA use and Hepatitis C. A final chapter presents the latest information on Haitian youth and young adults in Miami, Florida, with ethnographic background to illustrate the reasons for drug use in this and other ethnic minorities. This valuable source is extensively referenced and includes several helpful tables to clarify research data. New Drugs on the Street examines: ecstasy diverted pharmaceutical painkillers PCP embalming fluid narcotics analgesics (NA) drug use dynamics the changing street drug scene new drug combinations new drug-involved populations New Drugs on the Street reveals the nature and direction of the latest drug use and is essential reading for health professionals in the health social sciences, public health, nursing, and substance abuse fields that deal with low income, ethnic minority, and inner city populations.
National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Publisher : National Academies Press Page : 483 pages File Size : 55,7 Mb Release : 2017-09-28 Category : Medical ISBN : 9780309459570
Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Apple Best Books of 2021 Longlisted for the Andrew Carnegie Medal * Shortlisted for the Zocalo Book Prize From the New York Times bestselling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair. Sam Quinones traveled from Mexico to main streets across the U.S. to create Dreamland, a groundbreaking portrait of the opioid epidemic that awakened the nation. As the nation struggled to put back the pieces, Quinones was among the first to see the dangers that lay ahead: synthetic drugs and a new generation of kingpins whose product could be made in Magic Bullet blenders. In fentanyl, traffickers landed a painkiller a hundred times more powerful than morphine. They laced it into cocaine, meth, and counterfeit pills to cause tens of thousands of deaths-at the same time as Mexican traffickers made methamphetamine cheaper and more potent than ever, creating, Sam argues, swaths of mental illness and a surge in homelessness across the United States. Quinones hit the road to investigate these new threats, discovering how addiction is exacerbated by consumer-product corporations. “In a time when drug traffickers act like corporations and corporations like traffickers,” he writes, “our best defense, perhaps our only defense, lies in bolstering community.” Amid a landscape of despair, Quinones found hope in those embracing the forgotten and ignored, illuminating the striking truth that we are only as strong as our most vulnerable. Weaving analysis of the drug trade into stories of humble communities, The Least of Us delivers an unexpected and awe-inspiring response to the call that shocked the nation in Sam Quinones's award-winning Dreamland.
The inside story of a band of entrepreneurial upstarts who made millions selling painkillers—until their scheme unraveled, putting them at the center of a landmark criminal trial. • SOON TO BE THE MAJOR MOTION PICTURE PAIN HUSTLERS STARRING EMILY BLUNT AND CHRIS EVANS "Unfolds with the velocity and verve of a Scorsese film…A tour de force."—Patrick Radden Keefe, New York Times bestselling author of Empire of Pain and Say Nothing John Kapoor had already amassed a small fortune in pharmaceuticals when he founded Insys Therapeutics. It was the early 2000s, a boom time for painkillers, and he developed a novel formulation of fentanyl, the most potent opioid on the market. Kapoor, a brilliant immigrant scientist with relentless business instincts, was eager to make the most of his innovation. He gathered around him an ambitious group of young lieutenants. His head of sales—an unstable and unmanageable leader, but a genius of persuasion—built a team willing to pull every lever to close a sale, going so far as to recruit an exotic dancer ready to scrape her way up. They zeroed in on the eccentric and suspect doctors receptive to their methods. Employees at headquarters did their part by deceiving insurance companies. The drug was a niche product, approved only for cancer patients in dire condition, but the company’s leadership pushed it more widely, and together they turned Insys into a Wall Street sensation. But several insiders reached their breaking point and blew the whistle. They sparked a sprawling investigation that would lead to a dramatic courtroom battle, breaking new ground in the government’s fight to hold the drug industry accountable in the spread of addictive opioids. In The Hard Sell, National Magazine Award–finalist Evan Hughes lays bare the pharma playbook. He draws on unprecedented access to insiders of the Insys saga, from top executives to foot soldiers, from the patients and staff of far-flung clinics to the Boston investigators who treated the case as a drug-trafficking conspiracy, flipping cooperators and closing in on the key players. With colorful characters and true suspense, The Hard Sell offers a bracing look not just at Insys, but at how opioids are sold at the point they first enter the national bloodstream—in the doctor’s office.
An unflinching analysis of one of the major issues of our time — the shift from criminalization to regulation of recreational drugs. The “war on drugs” has failed. The cost of trying to control the production, sale, and use of recreational drugs through the criminal law is too high: unjust incarceration, illicit markets, tainted substances, exploited children, and an untaxed industry. But there is an alternative. The watchwords for governments controlling the consumption of alcohol, tobacco, junk food, and gambling are “permit but discourage.” All are legal, but harmful consumption is decreased by targeted regulatory strategies. That same approach should be adopted for drugs. Legalization and regulation can attack the underground economy, drive down excessive use, provide revenue for prevention, treatment, and counselling, and better protect children. Off the Street: Legalizing Drugs calls for a thoughtful, national discussion of the legalization and regulation of recreational drugs — the “least bad” way forward.
Understanding Street Drugs by David Emmett,Graeme Nice Pdf
This is a guide for any adult who works or lives with young people and is concerned about the modern drug culture. It explains the history of drug abuse, the present drug scene, slang, etc., and looks at rights and responsibilities. Previous ed.: published as Understanding drugs. 1996.
World Drug Report 2019 (Set of 5 Booklets) by United Nations Office on Drugs and Crime Pdf
The 2019 World Drug Report will include an updated overview of recent trends on production, trafficking and consumption of key illicit drugs. The Report contains a global overview of the baseline data and estimates on drug demand and supply and provides the reference point for information on the drug situation worldwide.
Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.
