New Insights Into Innate Immune Cell Based Immunotherapies In Cancer

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New insights into innate immune cell-based immunotherapies in cancer

Author : Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 51,6 Mb
Release : 2024-04-17
Category : Medical
ISBN : 9782832548042

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New insights into innate immune cell-based immunotherapies in cancer by Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta Pdf

New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Disease Biology and Signaling

Author : Jérôme Paggetti,Martina Seiffert,Etienne Moussay
Publisher : Frontiers Media SA
Page : 164 pages
File Size : 49,7 Mb
Release : 2022-01-31
Category : Medical
ISBN : 9782889742417

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New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Disease Biology and Signaling by Jérôme Paggetti,Martina Seiffert,Etienne Moussay Pdf

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives

Author : Jorge Morales-Montor,Mariana Segovia-Mendoza
Publisher : Academic Press
Page : 286 pages
File Size : 52,5 Mb
Release : 2020-10-16
Category : Science
ISBN : 9780128220283

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Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives by Jorge Morales-Montor,Mariana Segovia-Mendoza Pdf

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping. Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy. Provides basic and clinical evidence based on molecular interactions and clinical studies to address the risks and benefits of cancer immunotherapy Presents the results of new immunotherapy trials, discussing the state-of-the-art in different types of cancer Discusses targeted therapies approved by the FDA, along with therapies with clinical potential used in basic studies

New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy

Author : Jérôme Paggetti,Etienne Moussay,Martina Seiffert
Publisher : Frontiers Media SA
Page : 191 pages
File Size : 44,9 Mb
Release : 2022-03-02
Category : Medical
ISBN : 9782889742066

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New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy by Jérôme Paggetti,Etienne Moussay,Martina Seiffert Pdf

Topic Editor MS received funding from Bayer AG.

Patient Derived Tumor Xenograft Models

Author : Rajesh Uthamanthil,Peggy Tinkey,Elisa de Stanchina
Publisher : Academic Press
Page : 486 pages
File Size : 47,7 Mb
Release : 2016-10-13
Category : Medical
ISBN : 9780128040614

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Patient Derived Tumor Xenograft Models by Rajesh Uthamanthil,Peggy Tinkey,Elisa de Stanchina Pdf

Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry

Bio-Engineering Approaches to Cancer Diagnosis and Treatment

Author : Azadeh Shahidian,Majid Ghassemi,Javad Mohammadi,Mohadeseh Hashemi
Publisher : Academic Press
Page : 276 pages
File Size : 51,9 Mb
Release : 2020-05-14
Category : Technology & Engineering
ISBN : 9780128178102

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Bio-Engineering Approaches to Cancer Diagnosis and Treatment by Azadeh Shahidian,Majid Ghassemi,Javad Mohammadi,Mohadeseh Hashemi Pdf

Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer

New Insights into Fibrotic Signaling in Cancer

Author : Patrick Ming-Kuen Tang,Eric W-F Lam,Francis Jay Mussai,Dongmei Zhang,Chunjie Li
Publisher : Frontiers Media SA
Page : 142 pages
File Size : 44,6 Mb
Release : 2024-05-06
Category : Medical
ISBN : 9782832544754

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New Insights into Fibrotic Signaling in Cancer by Patrick Ming-Kuen Tang,Eric W-F Lam,Francis Jay Mussai,Dongmei Zhang,Chunjie Li Pdf

New Insights into Parvovirus Research

Author : Giorgio Gallinella
Publisher : MDPI
Page : 342 pages
File Size : 43,5 Mb
Release : 2020-04-15
Category : Medical
ISBN : 9783039283101

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New Insights into Parvovirus Research by Giorgio Gallinella Pdf

Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.

Tumor Microenvironment

Author : Alexander Birbrair
Publisher : Springer Nature
Page : 153 pages
File Size : 52,9 Mb
Release : 2020-02-08
Category : Science
ISBN : 9783030357238

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Tumor Microenvironment by Alexander Birbrair Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Hematopoietic Cells – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy

Author : Pawel Kalinski
Publisher : Springer
Page : 264 pages
File Size : 51,9 Mb
Release : 2017-12-22
Category : Medical
ISBN : 9783319675770

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Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy by Pawel Kalinski Pdf

The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.

Wintrobe's Clinical Hematology

Author : Robert J. Means, Jr.,George Rodgers,Bertil Glader,Daniel A. Arber,Frederick R. Appelbaum,Angela Dispenzieri,Todd A. Fehniger,Laura Michaelis,John P. Leonard
Publisher : Lippincott Williams & Wilkins
Page : 6360 pages
File Size : 41,8 Mb
Release : 2023-05-22
Category : Medical
ISBN : 9781975184704

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Wintrobe's Clinical Hematology by Robert J. Means, Jr.,George Rodgers,Bertil Glader,Daniel A. Arber,Frederick R. Appelbaum,Angela Dispenzieri,Todd A. Fehniger,Laura Michaelis,John P. Leonard Pdf

Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.

Cancer Immunotherapies: From Efficacy to Resistance Mechanisms

Author : Morten Hansen,Janin Chandra,Fernando Guimaraes,Nicolas Jacquelot,Yoshinobu Koguchi,Nathalie Labarriere,Ilaria Marigo,Lazar Vujanovic
Publisher : Frontiers Media SA
Page : 470 pages
File Size : 43,9 Mb
Release : 2022-06-29
Category : Medical
ISBN : 9782889764419

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Cancer Immunotherapies: From Efficacy to Resistance Mechanisms by Morten Hansen,Janin Chandra,Fernando Guimaraes,Nicolas Jacquelot,Yoshinobu Koguchi,Nathalie Labarriere,Ilaria Marigo,Lazar Vujanovic Pdf

Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.

Immune Cell Lineage Reprogramming in Cancer

Author : Jianmei Wu Leavenworth,Lewis Z. Shi,Xi Wang,Haiming Wei
Publisher : Frontiers Media SA
Page : 244 pages
File Size : 42,5 Mb
Release : 2022-02-22
Category : Medical
ISBN : 9782889744732

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Immune Cell Lineage Reprogramming in Cancer by Jianmei Wu Leavenworth,Lewis Z. Shi,Xi Wang,Haiming Wei Pdf

Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Cytotoxicity - Understanding Cellular Damage and Response

Author : Anil Sukumaran,Mahmoud Ahmed Mansour
Publisher : BoD – Books on Demand
Page : 246 pages
File Size : 48,6 Mb
Release : 2023-11-15
Category : Medical
ISBN : 9781803562452

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Cytotoxicity - Understanding Cellular Damage and Response by Anil Sukumaran,Mahmoud Ahmed Mansour Pdf

In the dynamic world of cellular biology, the intricate dance of life and death plays out through the lens of cytotoxicity. Delve deep into cellular responses’ mysteries, where threats and defenses wage a microscopic war, influencing the broader landscape of health and disease. This authoritative volume on cytotoxicity encapsulates the breadth and depth of current knowledge, illuminating pathways that have been meticulously charted and those yet to be discovered. Each chapter, penned by experts in the field, unveils the molecular intricacies, external triggers, and translational potential of understanding cellular damage. Key Highlights: •Comprehensive explorations of molecular mechanisms •Cutting-edge methodologies in cytotoxic research •Insight into the profound implications for drug development and disease therapeutics Whether you are a seasoned researcher, an aspiring scientist, or an avid learner, this book promises to challenge, enlighten, and inspire. As the boundary between known territories and uncharted frontiers blurs, Cytotoxicity - Understanding Cellular Damage and Response is your definitive guide to a world where cellular responses hold the keys to groundbreaking discoveries. This book is an indispensable resource for anyone eager to navigate the complexities of cell damage and defense. Join us on a journey into the cellular realm, where every page turns a new chapter in understanding, innovation, and hope.

Guide to Immunotherapy

Author : Suzanne L. Walker,Elizabeth Prechtel Dunphy
Publisher : Unknown
Page : 128 pages
File Size : 44,6 Mb
Release : 2018-10
Category : Electronic
ISBN : 1635930189

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Guide to Immunotherapy by Suzanne L. Walker,Elizabeth Prechtel Dunphy Pdf