New Insights Into Toxicity And Drug Testing

Author : Sivakumar Joghi Thatha Gowder
Publisher : BoD – Books on Demand
Page : 255 pages
File Size : 49,7 Mb
Release : 2013-01-23
Category : Medical
ISBN : 9789535109464

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New Insights into Toxicity and Drug Testing by Sivakumar Joghi Thatha Gowder Pdf

This book "New Insights into Toxicity and Drug Testing" covers all emerging technologies (profiling technologies, 3D cultures, next generation sequencing etc.), available methods and models to evaluate candidate drugs and medicinal plants with reference to toxicity, drug testing and development. This book is an original contribution of experts from different parts of the globe and the in-depth information will be a significant resource for scientists and physicians who are directly dealing with drugs / medicines and human life.

Author : Victor Kuete
Publisher : Elsevier
Page : 742 pages
File Size : 55,6 Mb
Release : 2014-05-30
Category : Medical
ISBN : 9780128004753

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Toxicological Survey of African Medicinal Plants by Victor Kuete Pdf

Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Author : Roberta Risoluti,Stefano Materazzi,Roshan B. Colah
Publisher : Frontiers Media SA
Page : 106 pages
File Size : 45,7 Mb
Release : 2021-05-12
Category : Science
ISBN : 9782889667628

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Frontiers in Hemoglobinopathies: New Insights and Methods by Roberta Risoluti,Stefano Materazzi,Roshan B. Colah Pdf

Author : Ana Cristina Andreazza,Gustavo Scola
Publisher : BoD – Books on Demand
Page : 246 pages
File Size : 55,6 Mb
Release : 2015-07-08
Category : Medical
ISBN : 9789535121404

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Toxicology Studies by Ana Cristina Andreazza,Gustavo Scola Pdf

The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick overview of principle aspects of toxins and toxicants in order to familiarize the key principles of toxicology. The book is divided into three main sections,; the first one discusses the role of mitochondrial dysfunction, oxidative stress and mitochondrial drug development. The second and third sections bring light to forensic toxicology and drug poisoning followed by environmental toxicity.

Author : Nuno Sousa,Hugo Leite-Almeida
Publisher : Frontiers Media SA
Page : 133 pages
File Size : 53,9 Mb
Release : 2021-11-12
Category : Science
ISBN : 9782889716227

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New Insights Into Behavioral Pharmacology by Nuno Sousa,Hugo Leite-Almeida Pdf

Author : Sivakumar Joghi Thatha Gowder
Publisher : BoD – Books on Demand
Page : 204 pages
File Size : 51,9 Mb
Release : 2017-05-10
Category : Science
ISBN : 9789535131335

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New Insights into Cell Culture Technology by Sivakumar Joghi Thatha Gowder Pdf

The book "New Insights into Cell Culture Technology" focuses on many advanced methods and techniques concerned with cell culture. The contributing authors have discussed various developments in cell culture methods, the application of insect cells for the efficient production of heterologous proteins, the expansion of human mesenchymal stromal cells for different clinical applications, the remote sensing of cell culture experiments and concepts for the development of cell culture bioprocess, continuous production of retroviral pseudotype vectors, and the production of oncolytic measles virus vectors for cancer therapy. This book is an original contribution of experts from different parts of the globe, and the in-depth information will be a significant resource for students, scientists, and physicians who are directly dealing with cells.["Culture" is essential for human life and also the life of a cell. - Sivakumar Gowder]

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology
Publisher : National Academies Press
Page : 300 pages
File Size : 48,7 Mb
Release : 2007-11-19
Category : Science
ISBN : 9780309178891

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Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology Pdf

The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

Author : Carla Vitorino,Carmen Balana,Célia Cabral
Publisher : Elsevier
Page : 788 pages
File Size : 52,8 Mb
Release : 2023-05-17
Category : Science
ISBN : 9780323999427

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New Insights into Glioblastoma by Carla Vitorino,Carmen Balana,Célia Cabral Pdf

New Insights into Glioblastoma: Diagnosis, Therapeutics and Theranostics provides a compendium of recent diagnostic and therapeutic advances in GBM, encompassing a pipeline of compounds and (bio) nanotechnology strategies that have stood out with potential increased antitumoral activity and capability to cross the blood-brain barrier. Issues and challenges related to their translation into the clinical practice and their contribution to the increase in survival rates and well-being of patients are addressed. This is a valuable resource for graduate students, oncologists, cancer researchers and members of the biomedical field who need to learn more on recent developments on the management of glioblastoma. The book is split in three parts: Diagnosis, focusing on biomarkers and techniques such PET/MRI, infrared thermography, and deep neural networks; Therapeutics, discussing new chemical entities, as natural products and repurposed drugs, and new formulation approaches, as nanotechnology-based and microRNA approaches; and Theranostics, explaining the role of omics, system-based approaches, and glioblastoma microenvironment. Provides guidance towards recent advances of new chemical entities and delivery strategies targeted to glioblastoma Includes overviews to help readers apply information in their research Encompasses summarizing diagrams and real-world examples to facilitate comprehension and enhance the applicability of the content

Author : Luis M. Botana,Amparo Alfonso
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 45,5 Mb
Release : 2016-03-02
Category : Technology & Engineering
ISBN : 9781118500347

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Phycotoxins by Luis M. Botana,Amparo Alfonso Pdf

Phycotoxins are a diverse group of poisonous substances produced by certain seaweed and algae in marine and fresh waters and are important to the scientific community for many reasons, the most obvious being that they pose food safety issues which requires a large investment to regularly monitor the presence of these compounds in foods.Phycotoxins: Chemistry and Biochemistry, second edition presents the most updated information available on phycotoxins. Major emphases are given to chemistry and biochemistry, while origins, mechanism of action, toxicology, and analytical methodology are also covered.Since the publication of the first edition, there have been major advances in the science of marine and aquatic toxins, as well as advances in toxicology, analytical chemistry and pharmacology. This fully revised and updated edition includes several new chapters, including those on ciguatoxins, pinnatoxin, ichthyotoxins, as well as new chapters on food safety control of marine toxins, climate change and water toxins, and microalgae as a source of nutraceuticals. The book will be of interest to toxicologists, marine, food, and plant scientists, as well as researchers and academics in the areas of food science, medicine, public health, toxicology, pharmacology and marine biology.

Author : Leobardo Manuel Gómez-Oliván
Publisher : Springer Nature
Page : 338 pages
File Size : 49,9 Mb
Release : 2020-10-14
Category : Science
ISBN : 9783030562946

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Non-Steroidal Anti-Inflammatory Drugs in Water by Leobardo Manuel Gómez-Oliván Pdf

This book gathers the main international research findings on non-steroidal anti-inflammatory drugs (NSAIDs) as emerging contaminants in water. It focuses on the major routes of exposure, and the destinations and life cycles of NSAIDs in water, as well as the manifestations of toxicity in different organisms. It also reviews the methods used in the detection, analysis and quantification of NSAIDs in water as well as the biological and chemical methods of removing them. Lastly, the book offers an overview of the legal frameworks in place and provides conclusions and recommendations for the future. Given its scope, the book is an indispensable resource for scientists in academia and industry, as well as for decision-makers involved in contamination assessment and environmental analysis and NGOs interested in the problem of water contamination by NSAIDs.

Author : Fang Zhao,Meng Li
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 54,5 Mb
Release : 2018-06-27
Category : Medical
ISBN : 9781789233704

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Drug Addiction by Fang Zhao,Meng Li Pdf

This edited volume is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of drug addiction. The book comprises single chapters authored by various researchers and edited by an expert active in the pertinent research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on drug addiction, and opens new possible research paths for further novel developments.

Author : Sonia Soloneski,Marcelo L. Larramendy
Publisher : BoD – Books on Demand
Page : 123 pages
File Size : 46,8 Mb
Release : 2021-09-15
Category : Medical
ISBN : 9781839687266

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Cytotoxicity by Sonia Soloneski,Marcelo L. Larramendy Pdf

This edited book, Cytotoxicity - New Insights into Toxic Assessment, is intended to present some strategies, methods, interpretations and recent advances in order to facilitate scientific research on in vitro toxic responses, presenting both theoretical and practical aspects.

Author : Rakesh Kumar Tekade
Publisher : Elsevier
Page : 854 pages
File Size : 46,6 Mb
Release : 2024-04-05
Category : Medical
ISBN : 9780443158438

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Public Health and Toxicology Issues in Drug Research, Volume 2 by Rakesh Kumar Tekade Pdf

Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on human health. Volume 2: Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics covers topics on pharmacokinetics and toxicokinetics such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. The book investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body. It discusses the mechanistic pathways of food toxicants and illustrates the molecular mechanisms of the chemopreventive role of dietary phytochemicals. It also delves into the toxic effects of medical treatments and materials. Ethical, legal, societal, and professional issues in toxicology round off the coverage providing a valuable resource to interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments. Discusses the impact of pharmaceuticals, food, and chemical toxicants on human health Examines the toxic effects of medical treatments, clinical administrations, and materials Explores public health issues around drug safety and toxicology

Author : Susana Solá,Joana Paiva Miranda
Publisher : Frontiers Media SA
Page : 240 pages
File Size : 53,9 Mb
Release : 2021-09-14
Category : Science
ISBN : 9782889713219

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The 11th Edition of the International Meeting of the SPCE-TC: Advances in Stem Cells and Cell Therapies by Susana Solá,Joana Paiva Miranda Pdf

Author : Nady el-Guebaly,Giuseppe Carrà,Marc Galanter,Alexander M. Baldacchino
Publisher : Springer Nature
Page : 1512 pages
File Size : 46,7 Mb
Release : 2020-11-03
Category : Medical
ISBN : 9783030363918

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Textbook of Addiction Treatment by Nady el-Guebaly,Giuseppe Carrà,Marc Galanter,Alexander M. Baldacchino Pdf

Addiction is increasingly being recognized as a major global public health issue, and an ever-growing number of medical specialties, psychological and social science training programs, and professional associations are including addiction as part of their training and continuing education curricula. The first edition of this book presented an overview of the spectrum of addiction-related problems across different cultures around the globe. Sharing the experience and wisdom of more than 260 leading experts in the field, and promoted by the International Society of Addiction Medicine, it compared and contrasted clinical practices in the field of addiction medicine on the basis of neurobiological similarities as well as epidemiological and socio-cultural differences. Building on the success of this inaugural edition, and taking into account the formal and informal comments received as well as an assessment of current need, this textbook presents general updated information while retaining the most requested sections of the first edition as demonstrated by the number of chapter downloads. It also provides a basic text for those preparing for the ISAM annual certification exam. Written by some 220 international experts, it is a valuable reference resource for anyone interested in medicine, psychology, nursing, and social science.