The 11th Edition Of The International Meeting Of The Spce Tc Advances In Stem Cells And Cell Therapies

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Advances in Stem Cell Therapy

Author : Nagwa El-Badri
Publisher : Humana Press
Page : 310 pages
File Size : 44,6 Mb
Release : 2016-11-18
Category : Science
ISBN : 9783319291499

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Advances in Stem Cell Therapy by Nagwa El-Badri Pdf

The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Regenerative and Cell Therapy

Author : A. Keating,K. Dicke,N. Gorin,R. Weber,H. Graf
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 45,8 Mb
Release : 2007-01-19
Category : Medical
ISBN : 9783540268437

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Regenerative and Cell Therapy by A. Keating,K. Dicke,N. Gorin,R. Weber,H. Graf Pdf

This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase,Mohan C Vemuri
Publisher : Springer Science & Business Media
Page : 458 pages
File Size : 53,6 Mb
Release : 2012-12-12
Category : Science
ISBN : 9781627032001

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Mesenchymal Stem Cell Therapy by Lucas G. Chase,Mohan C Vemuri Pdf

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Stem Cells in Regenerative Medicine

Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
Publisher : John Wiley & Sons
Page : 776 pages
File Size : 53,7 Mb
Release : 2015-09-14
Category : Science
ISBN : 9781118846209

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Stem Cells in Regenerative Medicine by Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss Pdf

This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.

Resident Stem Cells and Regenerative Therapy

Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
Publisher : Elsevier
Page : 410 pages
File Size : 42,7 Mb
Release : 2023-09-07
Category : Technology & Engineering
ISBN : 9780443152900

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Resident Stem Cells and Regenerative Therapy by Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho Pdf

Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures. Highlights basic research in tissue specific stem cells, experiments with animal models, and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications

Advances in Application of Stem Cells: From Bench to Clinics

Author : Firdos Alam Khan
Publisher : Springer Nature
Page : 320 pages
File Size : 42,7 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9783030781019

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Advances in Application of Stem Cells: From Bench to Clinics by Firdos Alam Khan Pdf

The field of stem cell biology is expanding with a continued surge of new information related to its applications. Over past few years, stem cells have been extensively used in cell therapy, tissue engineering, in vitro drug testing among others. At the moment there is no single book available which comprehensively describes the significance of various application of stem cells derived from embryonic and adult sources from lab to clinics. In this edited volume, we discuss basics and advanced topics of stem cells to help researchers, students and professional find the most important information in a single source of updated information about stem cells and relevant applications. This book is divided in 12 chapters and covers topics such as in vitro cell culture, 3D cell culture, cell therapy, tissue engineering, cell factory, cell functionality, in vitro drug testing, organ development, autologous transplantation, allogeneic transplantation, adult stem cells, multipotent stem cells, induced pluripotent stem cells, a pluripotent and embryonic stem cells.

Advances in Mesenchymal Stem Cells and Tissue Engineering

Author : Phuc Van Pham
Publisher : Springer
Page : 0 pages
File Size : 40,7 Mb
Release : 2023-08-21
Category : Science
ISBN : 3031386124

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Advances in Mesenchymal Stem Cells and Tissue Engineering by Phuc Van Pham Pdf

The fourth volume in this series is a proceedings volume based on papers presented at the 5th Innovations in Regenerative Medicine and Cancer Research conference. Chapters are written by some of the most innovative minds in stem cell and tissue engineering research, and provide a comprehensive overview of papers from the most recent conference. The volume addresses tissue engineering principles and applications, including current trends and challenges, as well as future directions. Cutting edge topics of interest include production of functional tissues, vascularization and immune responses, and functionalization of scaffolds. Volumes in this series are invaluable resources for active researchers, clinicians, and professionals in industry, as well as students across a broad range of fields.

Stem Cells in Cell Therapy and Regenerative Medicine

Author : Mehmet R. TOPCUL,Idil CETIN
Publisher : Unknown
Page : 128 pages
File Size : 49,7 Mb
Release : 2018-09-27
Category : Electronic
ISBN : 1632780216

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Stem Cells in Cell Therapy and Regenerative Medicine by Mehmet R. TOPCUL,Idil CETIN Pdf

The use stem cells in regenerative medicine are one of the most important issues of interestin the scientific field. Regeneration ability of stem cells, their differentiation characteristicsoffer a wide range of new projects and ideas. Valuable results in this regard provide importantcontributions to regenerative medicine. However, considering the presence of a cell groupthat affects the prognosis negatively, such as cancer stem cells, the issue becomes even morecomplicated. In this e-book, we aim to contribute to researchers working in the field of medicine,biology, molecular biology and genetics, pharmacy and veterinary medicine by referring stemcells, cancer stem cells and their importance in regenerative medicine.

Stem Cells Handbook

Author : Stewart Sell
Publisher : Humana Press
Page : 0 pages
File Size : 48,8 Mb
Release : 2013-08-16
Category : Science
ISBN : 146147695X

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Stem Cells Handbook by Stewart Sell Pdf

This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.

Progenitor and Stem Cell Technologies and Therapies

Author : Anthony Atala
Publisher : Woodhead Publishing
Page : 0 pages
File Size : 41,8 Mb
Release : 2012-03-15
Category : Medical
ISBN : 184569984X

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Progenitor and Stem Cell Technologies and Therapies by Anthony Atala Pdf

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology.

Cell Therapy - Cellular & Tissue Xenotransplantation

Author : Dr Ks Chan,Mike Chan,Dr Wong,Michelle Wong,Patricia Pan,Roni Lara Moya,Thomas Skutella
Publisher : Europa Edizioni
Page : 0 pages
File Size : 42,5 Mb
Release : 2024
Category : Health & Fitness
ISBN : 9791220146456

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Cell Therapy - Cellular & Tissue Xenotransplantation by Dr Ks Chan,Mike Chan,Dr Wong,Michelle Wong,Patricia Pan,Roni Lara Moya,Thomas Skutella Pdf

CELL THERAPY - CELLULAR & TISSUE XENOTRANSPLANTATION: Challenges, Progress and Current Applications. The team of researchers who collaborated with Dr. Chan, pioneer of these studies, has produced a document with a strong bibliographic depth for those who wish to explore the content. As we read in the preface: "For more than a century, xenotransplantation has been viewed as a potential solution to address the scarcity of human organs and tissue which are available for allotransplantation. However, due to numerous obstacles, including immunological rejection, regulatory restrictions, and ethical considerations; the progress of xenotransplantation has been stagnant and largely trapped in the preclinical stage. This book explores the challenges surrounding the field of xenotransplantation, looks into possible strategies to overcome them and discusses the potential and future of this field". Accurate images make it a very informative text. Prof. Dato' Sri Dr. Mike K.S. Chan, 62 yo Malaysian, Chairman of European Wellness Biomedical Group is a Scientist, Researcher, Author, and Educator in Stem Cells, Immunology and Bioregenerative Medicine for 39 years in Europe. He owns 40+ medical wellness, hospitals, and centres worldwide. Authored about 40+ scientific books and 90+ publications in the USA and the UK. Holds 40+ international patents in stem cells, immunology and biotechnology. He, - Board member, Head of Scientific Committee for Regenerative Medicine and Asian Chairman of ESAAM (European Society of Preventative, Regenerative and Anti-Aging Medicine) est. 2003 - Host the Society's Asian Chairman; Associate Professor of AASCP-USA (American Academy of Stem Cell Physicians) - Chairman of A4M-USA (American Academy of Anti-Aging Medicine) for Thailand - Chairman of Japan's Medical Association for Regenerative Medicine, MMJ (Multi-Dimensional Holistic Medical Team Japan) - Senator of BWA-Germany (Federal Association for Economic Development & Foreign Trade for China, Indonesia and Malaysia) - Healthcare advisor to renowned SSP (Swiss Strategic Partners), Zurich, which services Fortune 500 companies Chairman / Founder of the world's first stem cells association of the world, namely IASCT (International Association of Stem Cell Transplantation), USA. Chairman of the IACT (International Association of Cell Therapy), Switzerland. Appeared in more than 30 front covers worldwide. 30+ Multiple Award Winner for Invention & Innovations, Quality & Top Entrepreneur Leadership. 1,000+ lectures in international scientific & medical anti-ageing conferences. Prof. Dato Sri Dr. Michelle B.F. Wong, ND, PhD is a scientist, researcher and educator actively involved in research and development (R&D) work on stem cells focusing on Fetal Precursor Stem-Cell Therapy. She is the Co-Founder/Senior Technical Advisor and Researcher in FCTI Inc., specialising in Stem cell Research and Bio-Regenerative Medicine for more than three decades. A prominent speaker, Michelle Wong presents at educational programs and global conferences on stem cells, cell therapy and biological medicine for physicians and healthcare practitioners worldwide.

Human Embryonic Stem Cells

Author : Arlene Chiu,Mahendra S. Rao
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 54,6 Mb
Release : 2003-08-01
Category : Science
ISBN : 9781592594238

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Human Embryonic Stem Cells by Arlene Chiu,Mahendra S. Rao Pdf

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1844 pages
File Size : 43,5 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864534

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Cumulated Index Medicus by Anonim Pdf

Regulatory Aspects of Gene Therapy and Cell Therapy Products

Author : Maria Cristina Galli
Publisher : Springer Nature
Page : 243 pages
File Size : 51,7 Mb
Release : 2023-08-01
Category : Science
ISBN : 9783031345678

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Regulatory Aspects of Gene Therapy and Cell Therapy Products by Maria Cristina Galli Pdf

This book discusses the different regulatory pathways for Advanced Therapy Medicinal Products implemented by national agencies in North and South America, Europe and Asia and by international bodies in the effort of international harmonization. This book represents an update of the first edition, as it covers regulatory novelties and accumulated experience in the regions already addressed. In addition, this new edition offers a wider international perspective: new chapters are included covering Advanced Therapy Medicinal Products regulations in India, Malaysia, Spain and Thailand, the European Pharmacopoeia texts for gene therapy medicinal products as well as international harmonization programs. Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinical research to translational clinical research to licensure and therapeutic use of these innovative products. More specifically, each chapter offers insights into fundamental considerations that are essential for developers of Advanced Therapy Medicinal Products in the areas of product quality, pharmacology and toxicology, clinical trial design and HTA pathways, as well as pertinent ‘must-know’ guidelines and regulations. Regulatory Aspects of Gene Therapy and Cell Therapy Products: a Global Perspective is part of the American Society of Gene & Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy and the regulation of pharmaceuticals.