New Insights To Neuroimmune Biology

Author : Istvan Berczi
Publisher : Elsevier
Page : 306 pages
File Size : 44,8 Mb
Release : 2016-02-03
Category : Medical
ISBN : 9780128018330

Get Book

Insights to Neuroimmune Biology by Istvan Berczi Pdf

Insights to Neuroimmune Biology, Second Edition discusses the systemic regulatory network, coordination, organization, and interpretation of the rapidly accumulating knowledge on the topic of neuroimmune biology, with an ultimate goal of helping readers understand the function of higher organisms, including man, in their entire complexity. This publication provides assessments and interpretations of accumulated experimental evidence, enabling the scientific community to keep abreast of essential advancements of existing knowledge as we search for greater understanding of the biology of higher organisms. Provides information on the importance and applicability of the field of neuroimmunology Describes subjects that have shown significant recent developments Introduces a whole new dimension to neuroimmunology by discussing Epigenetic Immunoregulation Investigates the mechanisms and functions of the Neuroimmune Regulatory Supersystem Promotes translational research in the field of neuroimmune biology Covers challenges, such as dealing with problems of e.g., hypothalamic regulation of immune functions, interrelationships of stress and disease, epigenetic immunoregulation, neuroprotection, and neuroimmune regulation in pregnancy.

Author : Istvan Berczi
Publisher : Elsevier
Page : 284 pages
File Size : 52,9 Mb
Release : 2010-05-27
Category : Medical
ISBN : 0123846927

Get Book

New Insights to Neuroimmune Biology by Istvan Berczi Pdf

New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the role of tachykinins in asthma and allergic disease, defence and defeat reactions, cytokines, behavior and affective disorders, increased activity of type 1 helper T cell functions after reward stimulation. This book has relevance to the entire scientific community in Biology, Medicine and Veterinary medicine as it discusses molecular, cellular, organic and systemic aspects as well as the physological, pathophysiological and behavioral mechnisms which are involved in Neuroimmiune Biology.

Author : Valentin A. Pavlov,Niccolo Terrando
Publisher : Frontiers Media SA
Page : 222 pages
File Size : 48,6 Mb
Release : 2018-07-24
Category : Electronic
ISBN : 9782889455331

Get Book

Neuro-Immune Interactions in Inflammation and Autoimmunity by Valentin A. Pavlov,Niccolo Terrando Pdf

The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.

Author : Michal Schwartz,Anat London
Publisher : Yale University Press
Page : 316 pages
File Size : 50,6 Mb
Release : 2015-01-01
Category : Medical
ISBN : 9780300203479

Get Book

Neuroimmunity by Michal Schwartz,Anat London Pdf

Pathbreaking research offers new hope for treating brain diseases and injuries and for maintaining brain health even into old age In the past, the brain was considered an autonomous organ, self-contained and completely separate from the body's immune system. But over the past twenty years, neuroimmunologist Michal Schwartz, together with her research team, not only has overturned this misconception but has brought to light revolutionary new understandings of brain health and repair. In this book Schwartz describes her research journey, her experiments, and the triumphs and setbacks that led to the discovery of connections between immune system and brain. Michal Schwartz, with Anat London, also explains the significance of the findings for future treatments of brain disorders and injuries, spinal cord injuries, glaucoma, depression, and other conditions such as brain aging and Alzheimer's and Parkinson's diseases. Scientists, physicians, medical students, and all readers with an interest in brain function and its relationship to the immune system in health and disease will find this book a valuable resource. With general readers in mind, the authors provide a useful primer to explain scientific terms and concepts discussed in the book.

Author : Umasuthan Navaneethaiyer,Teruyuki Nakanishi,Samuel A. M. Martin,Javier Santander
Publisher : Frontiers Media SA
Page : 312 pages
File Size : 44,7 Mb
Release : 2023-06-01
Category : Medical
ISBN : 9782832524480

Get Book

New insights into mucosal-associated lymphoid tissues in fish by Umasuthan Navaneethaiyer,Teruyuki Nakanishi,Samuel A. M. Martin,Javier Santander Pdf

Author : Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer
Publisher : Cambridge University Press
Page : 357 pages
File Size : 45,7 Mb
Release : 2021-09-23
Category : Medical
ISBN : 9781108424042

Get Book

Textbook of Immunopsychiatry by Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer Pdf

An essential book summarizing cutting-edge evidence on the role of the immune system and immunotherapies in psychiatric disorders.

Author : Anonim
Publisher : ScholarlyEditions
Page : 1151 pages
File Size : 51,6 Mb
Release : 2013-07-22
Category : Medical
ISBN : 9781481652865

Get Book

HIV/AIDS: New Insights for the Healthcare Professional: 2013 Edition by Anonim Pdf

HIV/AIDS: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built HIV/AIDS: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of HIV/AIDS: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Brian Speer
Publisher : Elsevier Health Sciences
Page : 928 pages
File Size : 48,7 Mb
Release : 2015-12-21
Category : Medical
ISBN : 9780323243674

Get Book

Current Therapy in Avian Medicine and Surgery - E-Book by Brian Speer Pdf

A current and cutting-edge reference, Current Therapy in Avian Medicine and Surgery takes the popular Current Therapy approach in providing succinct and clear information pertinent to the medical care of avian species. Most chapters include an up-to-date delivery of the current state of knowledge on their subject material, and provide practical approaches and thought processes applicable to diagnosis and therapy where appropriate. Information is always easy to find, with topics including the latest advances in internal medicine; behavioral medicine; anesthesia, analgesia, and surgery. Sections dedicated to welfare, conservation, and practice risk management explore important, but less commonly discussed aspects of avian practice; and the pattern recognition portion of the text offers readers a view of what companion bird conditions are likely to be seen in practice in different parts of the world. Written by a team of highly regarded contributors from around the world, this text helps readers, regardless of location and current knowledge, develop and augment skills in the medical and surgical care of avian species. The Current Therapy format provides current, up-to-date, succinct and clear information pertinent to the medical and surgical care of avian species. Coverage of clinically significant topics includes current veterinary scientific literature and hot topics relating to today’s avian medicine and surgery. Coverage of a wide variety of bird species includes psittacines, pigeons, raptors, ratites, waterfowl, gallinaceous birds, and less common species. More than 800 full-color images show avian disease, management strategies and thought processes, and aid in formulating guidelines to care. World-renowned, expert contributors provide cutting-edge information, offering authoritative, accurate, and sometimes controversial opinions in many areas of study. Summary tables simplify the lookup of key facts and treatment guidelines. References in each chapter facilitate further reading and research on specific topics.

Author : Allan Siegel,Steven S. Zalcman
Publisher : Springer Science & Business Media
Page : 437 pages
File Size : 46,7 Mb
Release : 2008-11-09
Category : Medical
ISBN : 9780387848518

Get Book

The Neuroimmunological Basis of Behavior and Mental Disorders by Allan Siegel,Steven S. Zalcman Pdf

For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.

Author : Anonim
Publisher : ScholarlyEditions
Page : 335 pages
File Size : 45,6 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464970115

Get Book

Atherosclerosis: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

Atherosclerosis: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Atherosclerosis. The editors have built Atherosclerosis: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Atherosclerosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Atherosclerosis: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Davide Malagoli
Publisher : Academic Press
Page : 384 pages
File Size : 51,7 Mb
Release : 2016-07-21
Category : Medical
ISBN : 9780128020135

Get Book

The Evolution of the Immune System by Davide Malagoli Pdf

The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

Author : Anonim
Publisher : ScholarlyEditions
Page : 1894 pages
File Size : 46,6 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464969713

Get Book

HIV/AIDS: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about HIV/AIDS. The editors have built HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about HIV/AIDS in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : Elsevier
Page : 608 pages
File Size : 47,8 Mb
Release : 2008-06-18
Category : Science
ISBN : 0080559352

Get Book

Cytokines and the Brain by Anonim Pdf

This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment. *Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease *Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease *Includes novel approaches to the treatment of CNS disorders based on new experimental data *Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment

Author : Samuel Huber
Publisher : BoD – Books on Demand
Page : 266 pages
File Size : 53,9 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9789535127543

Get Book

New Insights into Inflammatory Bowel Disease by Samuel Huber Pdf

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 54,7 Mb
Release : 2007-04-17
Category : Science
ISBN : 1420008412

Get Book

Neural Plasticity and Memory by Federico Bermudez-Rattoni Pdf

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.