Glioma

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The Glioma Book

Michael E. Sughrue
The Glioma Book Book PDF

Author : Michael E. Sughrue
Publisher : Thieme
Page : 827 pages
File Size : 52,7 Mb
Release : 2019-10-25
Category : Medical
ISBN : 9781626234451

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The Glioma Book by Michael E. Sughrue Pdf

A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.

Diffuse Low-Grade Gliomas in Adults

Hugues Duffau
Diffuse Low Grade Gliomas in Adults Book PDF

Author : Hugues Duffau
Publisher : Springer Science & Business Media
Page : 498 pages
File Size : 50,7 Mb
Release : 2013-03-19
Category : Medical
ISBN : 9781447122135

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Diffuse Low-Grade Gliomas in Adults by Hugues Duffau Pdf

This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Glioma Imaging

Whitney B. Pope
Glioma Imaging Book PDF

Author : Whitney B. Pope
Publisher : Springer Nature
Page : 286 pages
File Size : 40,9 Mb
Release : 2019-11-11
Category : Medical
ISBN : 9783030273590

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Glioma Imaging by Whitney B. Pope Pdf

This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management. Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning about the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits

New Techniques for Management of ‘Inoperable’ Gliomas

Michael E. Sughrue,Isaac Yang
New Techniques for Management of Inoperable Gliomas Book PDF

Author : Michael E. Sughrue,Isaac Yang
Publisher : Academic Press
Page : 256 pages
File Size : 41,8 Mb
Release : 2019-08-03
Category : Medical
ISBN : 9780128136348

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New Techniques for Management of ‘Inoperable’ Gliomas by Michael E. Sughrue,Isaac Yang Pdf

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

Intracranial Gliomas Part I - Surgery

M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
Intracranial Gliomas Part I Surgery Book PDF

Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
Publisher : Karger Medical and Scientific Publishers
Page : 252 pages
File Size : 48,7 Mb
Release : 2017-12-14
Category : Medical
ISBN : 9783318060577

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Intracranial Gliomas Part I - Surgery by M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon Pdf

Aggressive surgical removal is generally considered the main initial management option for most intracranial gliomas. It often results in resolution or alleviation of neurological symptoms and signs, normalizes intracranial pressure, facilitates characterization of the neoplasm, creates optimal conditions for adjuvant therapy and neurorehabilitation, and leads to prolongation of progression-free and overall survival of patients. Leading experts in neurosurgical oncology have contributed to this volume, highlighting modern principles of surgery for both newly-diagnosed and recurrent intracranial gliomas in adult as well as pediatric patients. The first of a three-volume set, it details epidemiological aspects, defines the importance of preoperative imaging, and describes current perioperative adjuvant needs. In addition, contemporary methods of intraoperative neurophysiological monitoring, the value of brain mapping for functional preservation, tips to prevent complications, and postoperative results are presented and discussed. This book and its accompanying volumes are mainly directed at neurosurgeons, neuro-oncologists and other clinicians treating patients with brain tumors.

Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries

Alessandro Crimi,Spyridon Bakas,Hugo Kuijf,Bjoern Menze,Mauricio Reyes
Brainlesion Glioma Multiple Sclerosis Stroke and Traumatic Brain Injuries Book PDF

Author : Alessandro Crimi,Spyridon Bakas,Hugo Kuijf,Bjoern Menze,Mauricio Reyes
Publisher : Springer
Page : 517 pages
File Size : 43,7 Mb
Release : 2018-02-16
Category : Computers
ISBN : 9783319752389

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Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries by Alessandro Crimi,Spyridon Bakas,Hugo Kuijf,Bjoern Menze,Mauricio Reyes Pdf

This book constitutes revised selected papers from the Third International MICCAI Brainlesion Workshop, BrainLes 2017, as well as the International Multimodal Brain Tumor Segmentation, BraTS, and White Matter Hyperintensities, WMH, segmentation challenges, which were held jointly at the Medical Image computing for Computer Assisted Intervention Conference, MICCAI, in Quebec City, Canada, in September 2017. The 40 papers presented in this volume were carefully reviewed and selected from 46 submissions. They were organized in topical sections named: brain lesion image analysis; brain tumor image segmentation; and ischemic stroke lesion image segmentation.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess
Diseases of the Brain Head and Neck Spine 2020 2023 Book PDF

Author : Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess
Publisher : Springer Nature
Page : 252 pages
File Size : 44,8 Mb
Release : 2020-02-14
Category : Medical
ISBN : 9783030384906

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Diseases of the Brain, Head and Neck, Spine 2020–2023 by Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess Pdf

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Precision Molecular Pathology of Glioblastoma

José Javier Otero,Aline Paixao Becker
Precision Molecular Pathology of Glioblastoma Book PDF

Author : José Javier Otero,Aline Paixao Becker
Publisher : Springer Nature
Page : 266 pages
File Size : 51,8 Mb
Release : 2021-04-30
Category : Medical
ISBN : 9783030691707

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Precision Molecular Pathology of Glioblastoma by José Javier Otero,Aline Paixao Becker Pdf

This volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.

High-Grade Gliomas

Gene H. Barnett
High Grade Gliomas Book PDF

Author : Gene H. Barnett
Publisher : Springer Science & Business Media
Page : 493 pages
File Size : 42,5 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9781597451857

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High-Grade Gliomas by Gene H. Barnett Pdf

This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response. The first such “breakthrough” in high-grade glioma was the observation that loss of chromosomes 1p and 19q uniformly predict chemosensitivity in anaplastic oligodendrogliomas (1).

Brainstem Tumors

George I. Jallo,Mohammad Hassan A. Noureldine,Nir Shimony
Brainstem Tumors Book PDF

Author : George I. Jallo,Mohammad Hassan A. Noureldine,Nir Shimony
Publisher : Springer Nature
Page : 415 pages
File Size : 42,9 Mb
Release : 2020-05-09
Category : Medical
ISBN : 9783030387747

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Brainstem Tumors by George I. Jallo,Mohammad Hassan A. Noureldine,Nir Shimony Pdf

This illuminating and comprehensive work offers readers a thorough and detailed perspective of brainstem surgery as well as state-of-the-art discussion on the diagnosis and management of related pathologies. Hailing from around the globe and currently practicing in various countries in Asia, Europe, and North America, the expert authors of this work represent a wide range of disciplines and experiences, providing a comprehensive, interdisciplinary overview of brainstem surgery. Indeed, brainstem pathologies remain the most challenging to manage surgically due to the high eloquence and the deep and hidden location of the brainstem, turning surgical treatment of brainstem pathologies into one of the most complex and demanding fields in neurosurgery. This vital book guides readers through this very complex anatomical territory in which any pathology leads to grave consequences. Taking readers through the depth of the complex architecture of the brainstem in the clinical context, and emphasizing the evidence-based treatment of different brainstem pathologies while also reviewing what the future holds for the management of these pathologies, the book presents a review of state-of-the-art preoperative assessment modalities and surgical. The book covers brainstem-related pathologies from infancy to adulthood, and the text is enriched with diagnostic and surgical images that cover almost all types of brainstem lesions. The book is written in a way that neurosurgery specialists and fellows will feel comfortable navigating throughout its contents, and the enthusiastic neurosurgery resident will find this book to be a valuable guide. A major contribution to the clinical literature, Brainstem Tumors: Diagnosis and Management will also serve as a reference for anyone involved in the treatment of patients suffering from brainstem pathologies, including medical team members such as adult and pediatric neurosurgeons, neurologists, neurooncologists, residents and fellows, clinical neuropsychologists, electrophysiologists, neuroradiologists, and medical students who have a passion to learn about the assessment and surgical management of patients with brainstem diseases.

Glioblastoma:

Swapan K. Ray
Glioblastoma Book PDF

Author : Swapan K. Ray
Publisher : Springer Science & Business Media
Page : 427 pages
File Size : 43,5 Mb
Release : 2009-10-31
Category : Medical
ISBN : 9781441904102

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Glioblastoma: by Swapan K. Ray Pdf

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.

Novel Treatment Strategies for Glioblastoma

Stanley Stylli
Novel Treatment Strategies for Glioblastoma Book PDF

Author : Stanley Stylli
Publisher : Mdpi AG
Page : 282 pages
File Size : 41,8 Mb
Release : 2021-12-21
Category : Electronic
ISBN : 3036525998

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Novel Treatment Strategies for Glioblastoma by Stanley Stylli Pdf

This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.

Local Therapies for Glioma

M. Westphal,J.-C. Tonn,Z. Ram
Local Therapies for Glioma Book PDF

Author : M. Westphal,J.-C. Tonn,Z. Ram
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 50,5 Mb
Release : 2003-08-29
Category : Medical
ISBN : 3211403558

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Local Therapies for Glioma by M. Westphal,J.-C. Tonn,Z. Ram Pdf

In addition to surgery and radiotherapy, local treatment modalities for the management of brain tumours are increasingly being developed and clinically tested. This book describes for the first time basic tumour biology as well as all current procedures in progress at the most recent level of knowledge, presented by leading experts in the respective fields. Image guided resection procedures, fluorescence guided surgery, developments in interstitial radiosurgery are addressed, just as intracavitary chemotherapy and all current concepts and studies of interstitial targeted therapy. Owing to its topicality this book will remain for long the standard for this comprehensively treated subject.

The Duke Glioma Handbook

Allan H. Friedman
The Duke Glioma Handbook Book PDF

Author : Allan H. Friedman
Publisher : Cambridge University Press
Page : 237 pages
File Size : 50,9 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107065970

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The Duke Glioma Handbook by Allan H. Friedman Pdf

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Brain Tumor Imaging

Elke Hattingen,Ulrich Pilatus
Brain Tumor Imaging Book PDF

Author : Elke Hattingen,Ulrich Pilatus
Publisher : Springer
Page : 161 pages
File Size : 44,8 Mb
Release : 2015-09-02
Category : Medical
ISBN : 9783642450402

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Brain Tumor Imaging by Elke Hattingen,Ulrich Pilatus Pdf

This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.