Next Generation Antimicrobial Nanocoatings For Medical Devices And Implants

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Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants

Author : Pratima R. Solanki,P.V. Mohanan,Ravindra Pratap Singh,Jay Singh,Ajit Khosla,Kshitij RB Singh
Publisher : Elsevier
Page : 317 pages
File Size : 52,5 Mb
Release : 2024-01-12
Category : Technology & Engineering
ISBN : 9780323957571

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Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants by Pratima R. Solanki,P.V. Mohanan,Ravindra Pratap Singh,Jay Singh,Ajit Khosla,Kshitij RB Singh Pdf

Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants provides a detailed, up-to-date overview of nano-based antimicrobial coatings used to combat medical device-related biofilms. An introduction to biofilms and how they infect medical devices is included, as well as strategies/modification techniques used to target these biofilms. This book evaluates the various antimicrobial coatings formed using nanomaterials such as silver, inorganic materials, organic materials, carbon dots, surfactants, and electrospun fibers, specifically for us on medical devices and implants. Numerous coating methods are discussed along with the biological characterizations of these coating materials, and their toxicological and environmental impact.Next-generation Antimicrobial Nanocoatings for Medical Devices and Implants is a useful reference for materials scientists, biomedical engineers, and those working on the development of novel biomaterials for use in medical devices and implants. Provides a range of nanomaterials for use in antimicrobial coatings, including electrospun fibers, surfactants, carbon quantum dots, and more Details various modification approaches for targeting biofilms, as well as nanocoating characterization and methods for use on medical devices and implants Assesses the environmental and toxicological impact of antimicrobial nanocoatings

Ultrananocrystalline Diamond Coatings for Next-Generation High-Tech and Medical Devices

Author : Orlando Auciello
Publisher : Cambridge University Press
Page : 297 pages
File Size : 55,6 Mb
Release : 2022-07-21
Category : Technology & Engineering
ISBN : 9781009213431

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Ultrananocrystalline Diamond Coatings for Next-Generation High-Tech and Medical Devices by Orlando Auciello Pdf

A comprehensive guide to the science of a transformational ultrananocrystalline-diamond (UNCDTM) thin film technology enabling a new generation of high-tech and external and implantable medical devices. Edited and co-authored by a co-originator and pioneer in the field, it describes the synthesis and material properties of UNCDTM coatings and multifunctional oxide/nitride thin films and nanoparticles, and how these technologies can be integrated into the development of implantable and external medical devices and treatments of human biological conditions. Bringing together contributions from experts around the world, it covers a range of clinical applications, including ocular implants, glaucoma treatment devices, implantable prostheses, scaffolds for stem cell growth and differentiation, Li-ion batteries for defibrillators and pacemakers, and drug delivery and sensor devices. Technology transfer and regulatory issues are also covered. This is essential reading for researchers, engineers and practitioners in the field of high-tech and medical device technologies across materials science and biomedical engineering.

Biofilms and Implantable Medical Devices

Author : Ying Deng,Wei Lv
Publisher : Woodhead Publishing
Page : 238 pages
File Size : 43,8 Mb
Release : 2016-10-24
Category : Technology & Engineering
ISBN : 9780081003985

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Biofilms and Implantable Medical Devices by Ying Deng,Wei Lv Pdf

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Silver Nanoparticles for Antibacterial Devices

Author : Huiliang Cao
Publisher : CRC Press
Page : 634 pages
File Size : 43,7 Mb
Release : 2017-05-18
Category : Medical
ISBN : 9781315353470

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Silver Nanoparticles for Antibacterial Devices by Huiliang Cao Pdf

Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings together the synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively. With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.

Sustainable Approach to Protective Nanocoatings

Author : Garg, Rajni,Anjum, Ansar
Publisher : IGI Global
Page : 461 pages
File Size : 52,6 Mb
Release : 2024-02-27
Category : Technology & Engineering
ISBN : 9798369331378

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Sustainable Approach to Protective Nanocoatings by Garg, Rajni,Anjum, Ansar Pdf

It is essential to harness the potential of nanotechnology in a rapidly evolving industrial environment. As industries grapple with the demand for more advanced, efficient, and sustainable solutions, the intricate amalgamation of chemistry, materials science, physics, biology, and technology in nanotechnology emerges as both a beacon of promise and a complex puzzle. The groundbreaking book, Sustainable Approach to Protective Nanocoatings, serves as a transformative solution. Tailored for academic scholars seeking comprehensive insights, this book navigates the labyrinth of nanotechnology with precision, offering a roadmap for leveraging nanostructured materials and coatings to meet the demands of the modern industrial world. By seamlessly weaving together the intricate tapestry of research methodologies, applications, and technological advances, the book emerges as an indispensable resource for those poised at the intersection of academia and industry.

Surgical Tools and Medical Devices

Author : Waqar Ahmed,Mark J. Jackson
Publisher : Springer
Page : 691 pages
File Size : 51,7 Mb
Release : 2016-05-21
Category : Technology & Engineering
ISBN : 9783319334899

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Surgical Tools and Medical Devices by Waqar Ahmed,Mark J. Jackson Pdf

This new edition presents information and knowledge on the field of biomedical devices and surgical tools. The authors look at the interactions between nanotechnology, nanomaterials, design, modeling, and tools for surgical and dental applications, as well as how nanostructured surfaces can be created for the purposes of improving cell adhesion between medical devices and the human body. Each original chapter is revised in this second edition and describes developments in coatings for heart valves, stents, hip and knee joints, cardiovascular devices, orthodontic applications, and regenerative materials such as bone substitutes. There are also 8 new chapters that address: Microvascular anastomoses Inhaler devices used for pulmonary delivery of medical aerosols Surface modification of interference screws Biomechanics of the mandible (a detailed case study) Safety and medical devices The synthesis of nanostructured material Delivery of anticancer molecules using carbon nanotubes Nano and micro coatings for medical devices This book is appropriate for engineers, material scientists, chemists, physicists, biologists, medical and dental professionals with an interest in biomedical devices and tools, and researchers in the same fields.

Biofilms, Infection, and Antimicrobial Therapy

Author : John L. Pace,Mark E. Rupp,Roger G. Finch
Publisher : CRC Press
Page : 512 pages
File Size : 44,5 Mb
Release : 2005-08-29
Category : Science
ISBN : 9781420028232

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Biofilms, Infection, and Antimicrobial Therapy by John L. Pace,Mark E. Rupp,Roger G. Finch Pdf

Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange. Biofilms, Infection, and Antimicrobial Therapy provides an in-depth exploration of biofilms, offering broad background information, as well a detailed look at the serious concerns to which biofilm-associated infections give rise. Prosthetic device infections, such as those involving artificial heart valves, intravascular catheters, or prosthetic joints, are prime examples of biofilm-associated infections. With the increasing use of such devices in the modern practice of medicine, the prevalence of these infections is expected to increase. Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents. As biofilm-associated infections are particularly difficult to treat, they result in significant mortality, morbidity, and increased economic burden. Clearly, a better understanding of the pathogenesis of these infections and improved means for prevention and treatment are urgently needed! InBiofilms, Infection, and Antimicrobial Therapy, Drs Pace, Rupp, and Finch assemble the contributions of more than 50 of the world’s leading authorities on microbial biofilms who present recent findings on antibacterial tolerance and bacterial persistence associated with biofilms and discuses the implications of those findings with regard to human health. They explore the molecular mechanisms of bacterial adherence, biofilm formation, regulation of biofilm maintenance, and cell-to-cell communication and present the latest information on various treatment protocols that should aid physicians in the treatment of these refractory and often difficult-to-treat infections.

Handbook of Composites from Renewable Materials, Nanocomposites

Author : Vijay Kumar Thakur,Manju Kumari Thakur,Michael R. Kessler
Publisher : John Wiley & Sons
Page : 608 pages
File Size : 40,6 Mb
Release : 2017-03-29
Category : Technology & Engineering
ISBN : 9781119224501

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Handbook of Composites from Renewable Materials, Nanocomposites by Vijay Kumar Thakur,Manju Kumari Thakur,Michael R. Kessler Pdf

The Handbook of Composites From Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The handbook covers a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Together, the 8 volumes total at least 5000 pages and offers a unique publication. This 8th volume of the Handbook is solely focused on the Nanocomposites: Advanced Applications. Some of the important topics include but not limited to: virgin and recycled polymers applied to advanced nanocomposites; biodegradable polymer-carbon nanotube composites for water and wastewater treatment; eco-friendly nanocomposites of chitosan with natural extracts, antimicrobial agents and nanometals; controllable generation of renewable nanofibrils from green materials and their application in nanocomposites; nanocellulose and nanocellulose composites; poly (lactic acid) biopolymer composites and nanocomposites for biomedical and biopackaging applications; impact of nanotechnology in water treatment: carbon nanotube and graphene; nanomaterials in energy generation; sustainable green nanocomposites from bacterial bioplastics for food packaging applications; PLA-nanocomposites: a promising material for future from renewable resources; bio-composites from renewable resources: preparation and applications of chitosan-clay nanocomposites; nano materials: an advanced and versatile nano additive for kraft and paper industries; composites and nanocomposites based on polylactic acid obtaining; cellulose-containing scaffolds fabricated by electrospinning: applications in tissue engineering and drug delivery; biopolymer-based nanocomposites for environmental applications; calcium phosphate nanocomposites for biomedical and dental applications: recent developments; chitosan-metal nanocomposites: synthesis, characterization and applications; multi-carboxyl functionalized nano-cellulose/nano-bentonite composite for the effective removal and recovery of metal ions; biomimetic gelatin nanocomposite as a scaffold for bone tissue repair; natural starches-blended ionotropically-gelled microparticles/beads for sustained drug release and ferrogels: smart materials for biomedical and remediation applications.

Handbook of Bioceramics and Biocomposites

Author : Iulian Vasile Antoniac
Publisher : Springer
Page : 0 pages
File Size : 40,7 Mb
Release : 2016-05-05
Category : Technology & Engineering
ISBN : 3319124595

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Handbook of Bioceramics and Biocomposites by Iulian Vasile Antoniac Pdf

This handbook describes several current trends in the development of bioceramics and biocomposites for clinical use in the repair, remodelling, and regeneration of bone tissue. Comprehensive coverage of these materials allows fundamental aspects of the science and engineering to be seen in close relation to the clinical performance of dental and orthopaedic implants. Bioceramics and biocomposites appear to be the most dynamic area of materials development for both tissue engineering and implantable medical devices. Almost all medical specialties will continue to benefit from these developments, but especially dentistry and orthopaedics. In this Handbook, leading researchers describe the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Also described are technologies for bioceramics and biocomposites processing in order to fabricate medical devices for clinical use. Another important section of the book is dedicated to tissue regeneration with development of new matrices. A targeted or personalized treatment device reduces drug consumption and treatment expenses, resulting in benefits to the patient and cost reductions for public health systems. This authoritative reference on the state-of-the-art in the development and use of bioceramics and biocomposites can also serve as the basis of instructional course lectures for audiences ranging from advanced undergraduate students to post-graduates in materials science and engineering and biomedical engineering.

Advances in Biomaterials for Biomedical Applications

Author : Anuj Tripathi,Jose Savio Melo
Publisher : Springer
Page : 545 pages
File Size : 55,7 Mb
Release : 2017-01-24
Category : Technology & Engineering
ISBN : 9789811033285

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Advances in Biomaterials for Biomedical Applications by Anuj Tripathi,Jose Savio Melo Pdf

This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Antibacterial Surfaces

Author : Elena Ivanova,Russell Crawford
Publisher : Unknown
Page : 128 pages
File Size : 52,8 Mb
Release : 2015
Category : Electronic
ISBN : 3319185950

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Antibacterial Surfaces by Elena Ivanova,Russell Crawford Pdf

'Antibacterial Surfaces' covers the advances being made in the design of antibacterial surfaces, which have the ability to either prevent the initial attachment of bacterial cells, or kill any cells that come into contact with these surfaces. This book discusses the mechanisms associated with the attachment of bacteria to surfaces and the main strategies currently being employed to control the initial attachment processes. These strategies are expanded upon in the subsequent chapters, where the definition and description of antibacterial surfaces are clarified, as are the mechanisms that come into play when determining the effectiveness of an antibacterial surface. Subsequent chapters discuss a number of naturally occurring antibacterial surfaces, the methods currently being used for producing synthetic antibacterial surfaces, and the current and potential applications of such materials. This book will be of great interest to people who work with materials that need to remain free of bacterial films, from designing safer biomedical implants to the production of self-cleaning materials where the prevention of biofilm formation has significant economic advantages.

Pathogenesis of Wound and Biomaterial-Associated Infections

Author : Torkel Wadström,Ingvar Eliasson,Ian Holder,Asa Ljungh
Publisher : Springer Science & Business Media
Page : 537 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781447134541

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Pathogenesis of Wound and Biomaterial-Associated Infections by Torkel Wadström,Ingvar Eliasson,Ian Holder,Asa Ljungh Pdf

Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.

Surface Modification of Polymeric Biomaterials

Author : Buddy D. Ratner,David G. Castner
Publisher : Springer Science & Business Media
Page : 200 pages
File Size : 43,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781489919533

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Surface Modification of Polymeric Biomaterials by Buddy D. Ratner,David G. Castner Pdf

Applications of synthetic materials in medicine date back over 4000 year2. The Egyptians used linen as sutures. In the Roman Empire, gold was used in dentistry. Perhaps even earlier, ivory and bone may have been used in the body by practitioners of the healing arts. The historical origins of modem biomaterials science are also hard to precisely trace, but many of the ideas that define biomaterials as we know them today evolved in the late 1950s and early 1960s. Surface modification technology has played a prominent role in biomaterials science, and has paralleled the evolution of the modem field. In a symposium organized by the Artifical Heart Program of the NIH National Heart Institute and the Artificial Kidney program of the NIH National Institute of Arthritis and Metabolic Diseases, held in Atlantic City, New Jersey, in 1968, there were already a number of presentations on surface modification. Surface characterization at that time included scanning electron microscopy, ellipsometry, contact angle methods, and infrared internal reflection methods.

Racing for the Surface

Author : Bingyun Li,Thomas Fintan Moriarty,Thomas Webster,Malcolm Xing
Publisher : Springer Nature
Page : 648 pages
File Size : 41,5 Mb
Release : 2020-03-02
Category : Medical
ISBN : 9783030344757

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Racing for the Surface by Bingyun Li,Thomas Fintan Moriarty,Thomas Webster,Malcolm Xing Pdf

This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.

Nano-Antimicrobials

Author : Nicola Cioffi,Mahendra Rai
Publisher : Springer Science & Business Media
Page : 563 pages
File Size : 46,7 Mb
Release : 2012-02-26
Category : Technology & Engineering
ISBN : 9783642244278

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Nano-Antimicrobials by Nicola Cioffi,Mahendra Rai Pdf

There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance have created a pressing need to search for a new generation of antimicrobial agents, which are effective, safe and can be used for the cure of multidrug-resistant microbial infections. Nano-antimicrobials offer effective solutions for these challenges; the details of these new technologies are presented here. The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed.