Pathogenesis Of Wound And Biomaterial Associated Infections

Author : Torkel Wadström,Ingvar Eliasson,Ian Holder,Asa Ljungh
Publisher : Springer Science & Business Media
Page : 537 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781447134541

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Pathogenesis of Wound and Biomaterial-Associated Infections by Torkel Wadström,Ingvar Eliasson,Ian Holder,Asa Ljungh Pdf

Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.

Author : Peter Altmeyer,Klaus Hoffmann,Stephan el Gammal,Jerry Hutchinson
Publisher : Springer Science & Business Media
Page : 701 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642778827

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Wound Healing and Skin Physiology by Peter Altmeyer,Klaus Hoffmann,Stephan el Gammal,Jerry Hutchinson Pdf

On the occasion of the European Congress on Wound Healing and Skin Physiology (Bochum, Germany, November 1992), an international team of scientists and clinicians discussed the core topics in this important field of dermatological and surgical research. Themes include morphology and physiology, microcirculation and angiogenesis, biochemistry and immunology, microbiology and wound infection, non-invasive measurement techniques, wound repair, surgical treatment, dressings, and agents that promote wound healing.

Author : Per-Anders Mårdh,Karl H. Schleifer
Publisher : Coronet Books
Page : 232 pages
File Size : 51,9 Mb
Release : 1986
Category : Coagulase
ISBN : UOM:39015012562578

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Coagulase-negative Staphylococci by Per-Anders Mårdh,Karl H. Schleifer Pdf

Author : Samuel P. Sawan,Gurusamy Manivannan
Publisher : CRC Press
Page : 346 pages
File Size : 47,7 Mb
Release : 1999-12-10
Category : Technology & Engineering
ISBN : 9781482293944

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Antimicrobial/Anti-Infective Materials by Samuel P. Sawan,Gurusamy Manivannan Pdf

As our consciousness of microbes increases, it appears that our desire to control our interactions with germs also increases in proportion. This is clearly demonstrated by examining the incredible growth in the number and sales volume of consumer products with antimicrobial claims. In the medical field as well, there is much interest in the use of

Author : Giovanni Abatangelo,Luigi Donati,Wolfgang Vanscheidt
Publisher : Springer Science & Business Media
Page : 123 pages
File Size : 44,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642611308

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Proteolysis in Wound Repair by Giovanni Abatangelo,Luigi Donati,Wolfgang Vanscheidt Pdf

Extracellular matrix (ECM) turnover is a widespread but in completely understood process. Many studies have been con ducted with the aim of discovering the general mechanisms which produce and maintain the ECM in tissues. Wound re pair in animals has always been a suitable "tool" for exploring these mechanisms. In such a pathologic event, the different components of the healing system can be readily observed since they are exaggerated. It has now become clear that the regulation of protease/inhibitor activity is one of the most im portant steps in maintaining the integrity of ECM in the normal as well as in the pathologic state. As far as the repair process is concerned, a failure in such regulation may result in abnormal wound healing ranging from nonhealing wounds to hyper trophic scarring. Experimental findings have been directly applied in clinical practice. For example, the importance of debridement in nor mal and especially in poorly healing wounds has become much clearer in the recent past. Different methods have been proposed to obtain an optimal wound bed in order to perform skin transplantation. Both mechanical and physical debridement procedures un doubtedly offer some advantages and are essential when extensive third degree burns have to be treated. On the other hand, pain, excessive blood loss, and overall broad and indi scriminate debridement are common negative side effects. Thus, many enzymic formulations have been proposed and used in practice by clinicians all over the world.

Author : Donald Maxwell Brunette
Publisher : Springer Science & Business Media
Page : 1062 pages
File Size : 52,9 Mb
Release : 2001
Category : Medical
ISBN : 3540669361

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Titanium in Medicine by Donald Maxwell Brunette Pdf

This comprehensive book provides state-of-the-art scientific and technical information in a clear format and consistent structure making it suitable for formal course work or self-instruction. The authors are drawn not only from academic institutions but also from industry, so that practical aspects of implant fabrication and material handling are covered that are often lacking in biomaterials texts. Besides readers with a general interest in biomaterials, the book will interest materials investigators, surgeons and dentists using titanium implants, medical scientists and engineers, as well as lecturers at universities or institutes who would benefit by having ready access to authoritative information on the use of titanium for implants, devices and instruments. More information: http://www.titaniuminmedicine.com.

Author : Mario Campa,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461530367

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Pseudomonas aeruginosa as an Opportunistic Pathogen by Mario Campa,Mauro Bendinelli,Herman Friedman Pdf

Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism. It will provide a deeper understanding of the pathogen to physicians and surgeons caring for patients infected, or at risk of becoming infected, with Pseudomonas Aeruginosa.

Author : Cuie Wen
Publisher : Woodhead Publishing
Page : 449 pages
File Size : 55,7 Mb
Release : 2015-03-31
Category : Technology & Engineering
ISBN : 9781782423164

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Surface Coating and Modification of Metallic Biomaterials by Cuie Wen Pdf

Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. An expansive overview of surface modification techniques for biomedical use In-depth exploration of issues arising from metal biomaterial use Includes examples of applications in a clinical setting

Author : NinaM.K. Lamba
Publisher : Routledge
Page : 288 pages
File Size : 45,5 Mb
Release : 2017-10-19
Category : Medical
ISBN : 9781351423380

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Polyurethanes in Biomedical Applications by NinaM.K. Lamba Pdf

Polyurethanes in Biomedical Applications studies the use of polyurethanes in implanted medical devices. This analysis describes the concepts of polymer science, the manufacture of polyurethanes, and the biological responses to implant polyurethanes, reflecting the developments in biomaterials science and the interdisciplinary nature of bioengineering.

Author : W. Westerhof,Wolfgang Vanscheidt
Publisher : Springer Science & Business Media
Page : 109 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642788918

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Proteolytic Enzymes and Wound Healing by W. Westerhof,Wolfgang Vanscheidt Pdf

This book is the fruit of lectures given during the symposium "Proteolytic Enzymes and Wound Healing" at the Joint Meet ing of the Wound Healing Society and the European Tissue Repair Society held in Amsterdam, August 22-25, 1993. Look ing back, we can conclude with satisfaction that the meeting was a great success, with regard to both the number of partici pants and the scientific level. Enormous progress is being made in the field of wound heal ing and tissue repair. It was therefore of prime importance that one fundamental aspect in the healing of chronic wound- the proteolytic debridement of tissue necrosis - be given thorough attention during the above-mentioned symposium. Renowned authors dealt with the various aspects of proteoly tic enzymes and wound healing, so that a unique overview was given. The lectures were written up and arranged into the various chapters of this book, which should provide the reader with a practical guide in understanding and treating necrotic wounds. Wiete Westerhof, M. D., Ph. D. President of the Organizing Committee of the Joint Meeting of the Wound Healing Society and the European Tissue Repair Society Contents Pathobiology of Necrosis P. K. Das and W. Westerhof.. ................................... .

Author : A. Atilla Hincal,H.Süheyla Kas
Publisher : Springer Science & Business Media
Page : 286 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461553496

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Biomedical Science and Technology by A. Atilla Hincal,H.Süheyla Kas Pdf

Advancing with Biomedical Engineering Today, in most developed countries, modem hospitals have become centers of sophis ticated health care delivery using advanced technological methods. These have come from the emergence of a new interdisciplinary field and profession, commonly referred to as "Bio medical Engineering." Although what is included in the field of biomedical engineering is quite clear, there are some disagreements about its definition. In its most comprehensive meaning, biomedical engineering is the application of the principles and methods of engi neering and basic sciences to the understanding of the structure-function relationships in normal and pathological mammalian tissues, as well as the design and manufacture of prod ucts to maintain, restore, or improve tissue functions, thus assisting in the diagnosis and treat ment of patients. In this very broad definition, the field of biomedical engineering now includes: • System analysis (modeling, simulation, and control of the biological system) • Biomedical instrumentation (detection, measurement, and monitoring of physio logic signals) • Medical imaging (display of anatomic details or physiologic functions for diag nosis) • Biomaterials (development of materials used in prostheses or in medical devices) • Artificial organs (design and manufacture of devices for replacement or augmen tation of tissues or organs) • Rehabilitation (development oftherapeutic and rehabilitation procedures and de vices) • Diagnostics (development of expert systems for diagnosis of diseases) • Controlled drug delivery (development of systems for administration of drugs and other active agents in a controlled manner, preferably to the target area)

Author : Yuehuei H. An,Richard J. Friedman
Publisher : Springer Science & Business Media
Page : 647 pages
File Size : 43,5 Mb
Release : 2000-01-21
Category : Science
ISBN : 9781592592241

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Handbook of Bacterial Adhesion by Yuehuei H. An,Richard J. Friedman Pdf

Research on bacterial adhesion and its significance is a major field involving many different aspects of nature and human life, such as marine science, soil and plant ecology, most importantly, the biomedical field. The adhesion ofbacteria to the food industry, and human tissue surfaces and implanted biomaterial surfaces is an important step in the patho genesis of infection. Handbook 0/ Bacterial Adhesion: Principles, Methods, and Applications is an outgrowth of the editors' own quest for information on laboratory techniques for studying bacte rial adhesion to biomaterials, bone, and other tissues and, more importantly, a response to significant needs in the research community. This book is designed to be an experimental guide for biomedical scientists, biomaterials scientists, students, laboratory technicians, or anyone who plans to conduct bacterial adhesion studies. More specifically, it is intended for all those researchers facing the chal lenge of implant infections in such devices as orthopedic prostheses, cardiovascular devices or catheters, cerebrospinal fluid shunts or extradural catheters, thoracic or abdominal catheters, portosystemic shunts or bile stents, urological catheters or stents, plastic surgical implants, oral or maxillofacial implants, contraceptive implants, or even contact lenses. It also covers research methods for the study of bacterial adhesion to tis sues such as teeth, respiratory mucosa, intestinal mucosa, and the urinary tract. In short, it constitutes a handbook for biomechanical and bioengineering researchers and students at all levels.

Author : Itzahak Kahane,Itzhak Ofek
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461304159

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Toward Anti-Adhesion Therapy for Microbial Diseases by Itzahak Kahane,Itzhak Ofek Pdf

The emergence of pathogens resistant to conventional antimicrobial agents has forced us to intensify the efforts in search for new approaches to prevent infectious diseases. Such a direction was indicated in studies over the last two decades showing that adhesion of pathogens, primarily via glycoconjugate or protein receptors of the host tissue, is crucial for the infectious process. Moreover, it was found that infection can be prevented by blocking adhesion of the pathogen to mucosal surfaces of the host. The various aspects of interference with the process of microbial adhesion as a way of preventing diseases were the subject of the Bat-Sheva Seminar, "Towards Anti-Adhesion Therapy of Microbial Infectious Diseases," held in Zichron Yaakov, Israel, February 25 to March I, 1996. A major aim of the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel, which sponsors a series of seminars, ours among them, is to provide the necessary tools and settings for international forums and exposure of young scientists and promising students to the state of the art of the field. This goal has been achieved during the week's discussions, and its major aspects are presented in this compendium. The seminar's participants, as well as the readers of this book, thank the founder and Foundation for their support. This book includes the major themes of this rapidly growing area. However, by no means do we intend to cover every bit and piece in it. The book's first section deals with the lectin-sugar interactions and their inhibitors.

Author : Vincenzo Savini
Publisher : Academic Press
Page : 322 pages
File Size : 48,5 Mb
Release : 2018-03-14
Category : Science
ISBN : 9780128135488

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Pet-to-Man Travelling Staphylococci by Vincenzo Savini Pdf

Pet-to-Man Travelling Staphylococci: A World in Progress explores Staphylococci, a dangerous pathogen that affects both humans and animals with a wide range of infection states. This bacteria can spread rapidly as a commensal organism in both humans and pets, and is an agent of disease. Staphylococci are potentially highly virulent pathogens which require urgent medical attention. In addition, Staphylococci remain a threat within hospital environments, where they can quickly spread across a patient population. This book explores the organisms' resistance to many compounds used to treat them, treatment failure and multidrug resistant staphylococci, amongst other related topics. Focuses not only on man and animal staphylococcal diseases, but on the role of shared household in man-to-pet (and vice versa) transmission Underlines the importance of professional exposure to mammals (i.e. veterinary and farm personnel) in the establishment of shared colonization's and related diseases Highlights the impact of shared staphylococci and virulence determinants in human and veterinary pathology Sheds light on the way staphylococci may be recognized in clinical laboratories

Author : Joshua Boateng
Publisher : John Wiley & Sons
Page : 444 pages
File Size : 46,9 Mb
Release : 2020-03-09
Category : Science
ISBN : 9781119433262

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Therapeutic Dressings and Wound Healing Applications by Joshua Boateng Pdf

The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.