Nmr In Chemistry

Author : Harald Günther
Publisher : John Wiley & Sons
Page : 842 pages
File Size : 54,5 Mb
Release : 2013-12-13
Category : Science
ISBN : 9783527674770

Get Book

NMR Spectroscopy by Harald Günther Pdf

Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.

Author : S. A. Richards,J. C. Hollerton
Publisher : John Wiley & Sons
Page : 345 pages
File Size : 52,7 Mb
Release : 2010-12-07
Category : Science
ISBN : 9780470977224

Get Book

Essential Practical NMR for Organic Chemistry by S. A. Richards,J. C. Hollerton Pdf

This book describes the use of NMR spectroscopy for dealing with problems of small organic molecule structural elucidation. It features a significant amount of vital chemical shift and coupling information but more importantly, it presents sound principles for the selection of the techniques relevant to the solving of particular types of problem, whilst stressing the importance of extracting the maximum available information from the simple 1-D proton experiment and of using this to plan subsequent experiments. Proton NMR is covered in detail, with a description of the fundamentals of the technique, the instrumentation and the data that it provides before going on to discuss optimal solvent selection and sample preparation. This is followed by a detailed study of each of the important classes of protons, breaking the spectrum up into regions (exchangeables, aromatics, heterocyclics, alkenes etc.). This is followed by consideration of the phenomena that we know can leave chemists struggling; chiral centres, restricted rotation, anisotropy, accidental equivalence, non-first-order spectra etc. Having explained the potential pitfalls that await the unwary, the book then goes on to devote chapters to the chemical techniques and the most useful instrumental ones that can be employed to combat them. A discussion is then presented on carbon-13 NMR, detailing its pros and cons and showing how it can be used in conjunction with proton NMR via the pivotal 2-D techniques (HSQC and HMBC) to yield vital structural information. Some of the more specialist techniques available are then discussed, i.e. flow NMR, solvent suppression, Magic Angle Spinning, etc. Other important nuclei are then discussed and useful data supplied. This is followed by a discussion of the neglected use of NMR as a tool for quantification and new techniques for this explained. The book then considers the safety aspects of NMR spectroscopy, reviewing NMR software for spectral prediction and data handling and concludes with a set of worked Q&As.

Author : T. Claridge
Publisher : Elsevier
Page : 408 pages
File Size : 42,8 Mb
Release : 1999-12-24
Category : Science
ISBN : 0080427995

Get Book

High-resolution NMR Techniques in Organic Chemistry by T. Claridge Pdf

From the initial observation of proton magnetic resonance in water and in paraffin, the discipline of nuclear magnetic resonance has seen unparalleled growth as an analytical method. Modern NMR spectroscopy is a highly developed, yet still evolving, subject which finds application in chemistry, biology, medicine, materials science and geology. In this book, emphasis is on the more recently developed methods of solution-state NMR applicable to chemical research, which are chosen for their wide applicability and robustness. These have, in many cases, already become established techniques in NMR laboratories, in both academic and industrial establishments. A considerable amount of information and guidance is given on the implementation and execution of the techniques described in this book.

Author : B. I. Ionin
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468417852

Get Book

NMR Spectroscopy in Organic Chemistry by B. I. Ionin Pdf

In recent years high-resolution nuclear magnetic resonance spec troscopy has found very wide application in organie chemistry in structural and physicochemical investigations and. also in the study of the characteristics of organic compounds which are re lated to the distribution of the electron cloud in the molecules. The vigorous development of this method, which may really be re garded as an independent branch of science, is the result of ex tensive progress in NMR technology, the refinement of its theory, and the accumulation of large amounts of experimental material, which has been correlated by empiricallaws and principles. The literature directly concerned with the NMR method and its applica tion has now grown to such an extent that a complete review of it is practically impossible. Therefore the authors have limited themselves to an examination of only the most important, funda mental, and general investigations. The book consists of six chapters. In the first chapter we have attempted to present the fundamentals of the NMR method in such a way that the reader with little knowledge of the subject will be able to use the method in practical work for investigating simple compounds and solving simple problems. The three subsequent chapters give a deeper analysis of the method, while the last two chapters and the appendix illustrate the various applications of NMR spectroscopy in organic chemistry.

Author : Atta-ur-Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 289 pages
File Size : 52,7 Mb
Release : 2016-11-22
Category : Science
ISBN : 9781681082875

Get Book

Applications of NMR Spectroscopy by Atta-ur-Rahman,M. Iqbal Choudhary Pdf

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The fifth volume of the series features several reviews focusing on NMR spectroscopic techniques for identifying natural and synthetic compounds (polymer and peptide characterization, GABA in tinnitus affected mice), medical diagnosis and therapy (gliomas) and food analysis. The spectroscopic methods highlighted in this volume include high resolution proton magnetic resonance spectroscopy and solid state NMR.

Author : Neil E. Jacobsen
Publisher : John Wiley & Sons
Page : 640 pages
File Size : 43,9 Mb
Release : 2007-09-10
Category : Science
ISBN : 9780470173343

Get Book

NMR Spectroscopy Explained by Neil E. Jacobsen Pdf

NMR Spectroscopy Explained : Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology provides a fresh, practical guide to NMR for both students and practitioners, in a clearly written and non-mathematical format. It gives the reader an intermediate level theoretical basis for understanding laboratory applications, developing concepts gradually within the context of examples and useful experiments. Introduces students to modern NMR as applied to analysis of organic compounds. Presents material in a clear, conversational style that is appealing to students. Contains comprehensive coverage of how NMR experiments actually work. Combines basic ideas with practical implementation of the spectrometer. Provides an intermediate level theoretical basis for understanding laboratory experiments. Develops concepts gradually within the context of examples and useful experiments. Introduces the product operator formalism after introducing the simpler (but limited) vector model.

Author : William Kemp
Publisher : Free Press
Page : 240 pages
File Size : 44,8 Mb
Release : 1988
Category : Nuclear magnetic resonance spectroscopy
ISBN : 002949401X

Get Book

NMR in Chemistry by William Kemp Pdf

Author : David W. Boykin
Publisher : CRC Press
Page : 336 pages
File Size : 54,5 Mb
Release : 1990-11-20
Category : Science
ISBN : 0849348676

Get Book

17 0 NMR Spectroscopy in Organic Chemistry by David W. Boykin Pdf

This book provides a comprehensive review of the application of 17O NMR spectroscopy to organic chemistry. Topics include the theoretical aspects of chemical shift, quadrupolar and J coupling; 17O enrichment; the effect of steric interactions on 17O chemical shifts of functional groups in flexible and rigid systems; the application of 17O NMR spectroscopy to hydrogen bonding investigations; mechanistic problems in organic and bioorganic chemistry; and 17O NMR spectroscopy of oxygen monocoordinated to carbon in alcohols, ethers, and derivatives. Recent results that show correlations between molecular geometry, determined by X-ray studies and estimated by molecular mechanics calculations, and 17O chemical shifts are also covered. 17O Spectroscopy in Organic Chemistry provides important reference information for organic chemists and other scientists interested in 17O NMR spectroscopy as a tool for obtaining new structural and chemical data about organic molecules.

Author : A.E. Derome
Publisher : Elsevier
Page : 299 pages
File Size : 41,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483286426

Get Book

Modern NMR Techniques for Chemistry Research by A.E. Derome Pdf

Presents an introduction to modern NMR methods at a level suited to organic and inorganic chemists engaged in the solution of structural and mechanistic problems. The book assumes familiarity only with the simple use of proton and carbon spectra as sources of structural information and describes the advantages of pulse and Fourier transform spectroscopy which form the basis of all modern NMR experiments. Discussion of key experiments is illustrated by numerous examples of the solutions to real problems. The emphasis throughout is on the practical side of NMR and the book will be of great use to chemists engaged in both academic and industrial research who wish to realise the full possibilities of the new wave NMR.

Author : L. M. Jackman,S. Sternhell
Publisher : Elsevier
Page : 474 pages
File Size : 55,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483280943

Get Book

Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry by L. M. Jackman,S. Sternhell Pdf

Application of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry, Second Edition covers the theoretical background necessary for the intelligent application of NMR spectroscopy to common problems encountered in organic chemistry. This book is composed of five parts, and begins with introduction to the theory and practice of nuclear magnetic resonance. The succeeding chapter deals with the theory of chemical effects in NMR spectroscopy. These topics are followed by a discussion on the application of chemical shift to organic compound analysis and the principles of the spin-spin coupling .The final chapter considers the applications of time- dependent phenomena in NMR spectroscopy. This book will prove useful to analytical chemists and researchers in the allied fields.

Author : J.W. Akitt,B. E. Mann
Publisher : CRC Press
Page : 400 pages
File Size : 50,7 Mb
Release : 2017-12-21
Category : Science
ISBN : 9781482268379

Get Book

NMR and Chemistry by J.W. Akitt,B. E. Mann Pdf

Keeping mathematics to a minimum, this book introduces nuclear properties, nuclear screening, chemical shift, spin-spin coupling, and relaxation. It is one of the few books that provides the student with the physical background to NMR spectroscopy from the point of view of the whole of the periodic table rather than concentrating on the narrow applications of 1H and 13C NMR spectroscopy. Aids to structure determination, such as decoupling, the nuclear Overhauser effect, INEPT, DEPT, and special editing, and two dimensional NMR spectroscopy are discussed in detail with examples, including the complete assignment of the 1H and 13C NMR spectra of D-amygdain. The authors examine the requirements of a modern spectrometer and the effects of pulses and discuss the effects of dynamic processes as a function of temperature or pressure on NMR spectra. The book concludes with chapters on some of the applications of NMR spectroscopy to medical and non-medical imaging techniques and solid state chemistry of both I = F1/2 and I > F1/2 nuclei. Examples and problems, mainly from the recent inorganic/organometallic chemistry literature support the text throughout. Brief answers to all the problems are provided in the text with full answers at the end of the book.

Author : P. J. Hore
Publisher : Oxford University Press, USA
Page : 121 pages
File Size : 52,8 Mb
Release : 2015
Category : Science
ISBN : 9780198703419

Get Book

Nuclear Magnetic Resonance by P. J. Hore Pdf

Although the practice of NMR spectroscopy has changed hugely over the last 20 years, the physical principles of liquid-state NMR, with which this book is concerned, remain essentially the same. The origins of chemical shifts, spin-spin couplings, chemical exchange, and spin relaxation, and their effects on the appearance of NMR spectra, were all already pretty well understood by 1995, at least at the level of most undergraduate chemistry courses. As a consequence, the ground covered by this second edition does not differ greatly from the first. The most significant additions, aimed at making the coverage of experimental techniques a little more contemporary, are sections on INEPT, HSQC, and three-dimensional NMR.

Author : Julie Fisher
Publisher : CRC Press
Page : 364 pages
File Size : 42,5 Mb
Release : 2014-10-13
Category : Science
ISBN : 9781466592247

Get Book

Modern NMR Techniques for Synthetic Chemistry by Julie Fisher Pdf

A blend of theory and practical advice, Modern NMR Techniques for Synthetic Chemistry illustrates how NMR spectroscopy can be used to determine the abundance, size, shape, and function of organic molecules. It provides you with a description the NMR technique used (more pictorial than mathematical), indicating the most common pulse sequences, some practical information as appropriate, followed by illustrative examples. This format is followed for each chapter so you can skip the more theoretical details if the practical aspects are what interest you. Following a discussion of basic parameters, the book describes the utility of NMR in detecting and quantifying dynamic processes, with particular emphasis on the usefulness of saturation-transfer (STD) techniques. It details pulsed–field gradient approaches to diffusion measurement, diffusion models, and approaches to ‘inorganic’ nuclei detection, important as many synthetic pathways to new organics involve heavier elements. The text concludes with coverage of applications of NMR to the analysis of complex mixtures, natural products, carbohydrates, and nucleic acids—all areas of activity for researchers working at the chemistry-life sciences interface. The book’s unique format provides some theoretical insight into the NMR technique used, indicating the most common pulse sequences. The book draws upon several NMR methods that are resurging or currently hot in the field and indicates the specific pulse sequence used by various spectrometer manufacturers for each technique. It examines the analysis of complex mixtures, a feature not found in most books on this topic.

Author : Harald Günther
Publisher : Unknown
Page : 612 pages
File Size : 53,7 Mb
Release : 1995-03-15
Category : Science
ISBN : UOM:39015059080021

Get Book

NMR Spectroscopy by Harald Günther Pdf

As with its predecessor, this edition uses a practical non-mathematical approach. Features a number of recent developments in the field including two-dimensional methods, solid state NMR and an enlarged treatment of Fourier Transform methods. Contains numerous two-color diagrams.

Author : Jeremy K. M. Sanders
Publisher : OUP Oxford
Page : 150 pages
File Size : 45,9 Mb
Release : 1993
Category : Science
ISBN : STANFORD:36105017054201

Get Book

Modern NMR Spectroscopy by Jeremy K. M. Sanders Pdf

Nuclear magnetic resonance techniques have advanced dramatically in recent years, and are now more powerful and more versatile than ever before. To exploit these techniques efficiently, the chemist must have both an understanding of their theoretical basis and the ability to interpret the spectra accurately. The new edition of this established workbook develops the latter skill to an advanced level by a combination of worked examples and set problems that cover one- and two-dimensional NMR techniques applied to organic and inorganic systems. Most of the problems are genuine research examples, and this new edition contains eight pages of problems drawn from very recent research work. This second edition is fully compatible with the second edition of Modern NMR Spectroscopy: a guide for chemists, and the two books are thoroughly cross referenced throughout.