Novel Approaches Towards The Treatment Of Hiv Infection

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Novel Approaches for the Delivery of Anti-HIV Drugs

Author : José das Neves
Publisher : MDPI
Page : 208 pages
File Size : 52,6 Mb
Release : 2020-05-20
Category : Medical
ISBN : 9783039219001

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Novel Approaches for the Delivery of Anti-HIV Drugs by José das Neves Pdf

HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

HIV-1 Latency

Author : Guido Silvestri,Mathias Lichterfeld
Publisher : Springer
Page : 248 pages
File Size : 43,5 Mb
Release : 2018-10-11
Category : Medical
ISBN : 9783030028169

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HIV-1 Latency by Guido Silvestri,Mathias Lichterfeld Pdf

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection

Author : World Health Organization
Publisher : Unknown
Page : 429 pages
File Size : 55,9 Mb
Release : 2016
Category : AIDS (Disease)
ISBN : 9241549688

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Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by World Health Organization Pdf

These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.

Exploring Novel Approaches to Eliminate HIV Reservoirs to Achieve a Cure for HIV

Author : Renee Marije Van Der Sluis,Matthew Parsons,Andrés Finzi
Publisher : Frontiers Media SA
Page : 111 pages
File Size : 40,8 Mb
Release : 2021-04-07
Category : Science
ISBN : 9782889666669

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Exploring Novel Approaches to Eliminate HIV Reservoirs to Achieve a Cure for HIV by Renee Marije Van Der Sluis,Matthew Parsons,Andrés Finzi Pdf

Novel Approaches for the Delivery of Anti-HIV Drugs

Author : José das Neves
Publisher : Unknown
Page : 208 pages
File Size : 46,8 Mb
Release : 2020
Category : Technology (General)
ISBN : 3039219014

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Novel Approaches for the Delivery of Anti-HIV Drugs by José das Neves Pdf

HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 49,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

HIV Vaccines and Cure

Author : Linqi Zhang,Sharon R. Lewin
Publisher : Springer
Page : 318 pages
File Size : 55,8 Mb
Release : 2018-07-20
Category : Medical
ISBN : 9789811304842

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HIV Vaccines and Cure by Linqi Zhang,Sharon R. Lewin Pdf

This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Practice Issues in HIV/AIDS Services

Author : Ronald J. Mancoske,James Donald Smith
Publisher : Psychology Press
Page : 242 pages
File Size : 45,9 Mb
Release : 2004
Category : Health & Fitness
ISBN : 9780789023018

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Practice Issues in HIV/AIDS Services by Ronald J. Mancoske,James Donald Smith Pdf

Practice Issues in HIV/AIDS Services: Empowerment-Based Models and Program Applications provides a sound framework of intervention practices for case managers and care coordinators to help HIV/AIDS patients live longer and healthier lives. This book focuses on client-based care that addresses the social and psychological needs of the patient as well as his or her physical and medical requirements. Filled with concrete information and recommendations from practitioners and researchers, this instructive text will help increase the effectiveness of your role in the client's treatment.

HIV/AIDS in the Post-HAART Era

Author : John C. Hall,Brian John Hall,Clay J. Cockerell
Publisher : PMPH-USA
Page : 1052 pages
File Size : 45,5 Mb
Release : 2011
Category : AIDS (Disease)
ISBN : 1607951053

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HIV/AIDS in the Post-HAART Era by John C. Hall,Brian John Hall,Clay J. Cockerell Pdf

The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.

Neurocognitive Complications of HIV-Infection

Author : Lucette A. Cysique,Sean B. Rourke
Publisher : Springer Nature
Page : 548 pages
File Size : 46,6 Mb
Release : 2021-10-29
Category : Medical
ISBN : 9783030807597

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Neurocognitive Complications of HIV-Infection by Lucette A. Cysique,Sean B. Rourke Pdf

This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com

Disease Control Priorities in Developing Countries

Author : Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove
Publisher : World Bank Publications
Page : 1449 pages
File Size : 51,5 Mb
Release : 2006-04-02
Category : Medical
ISBN : 9780821361801

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Disease Control Priorities in Developing Countries by Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove Pdf

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.