Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 304a Inherent Biodegradability In Soil
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OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 304A: Inherent Biodegradability in Soil by OECD Pdf
The method described in this Test Guideline is designed for the evaluation of the mineralisation rate of a 14C-labelled compound in soil. The method is applicable to volatile or non-volatile, soluble or insoluble compounds which are not inhibitory ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 308: Aerobic and Anaerobic Transformation in Aquatic Sediment Systems by OECD Pdf
This Test Guideline describes a laboratory test method to assess aerobic and anaerobic transformation of organic chemicals in aquatic sediment systems. The method permits the measurement of (i) the transformation rate of the test substance in a ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 302A: Inherent Biodegradability: Modified SCAS Test by OECD Pdf
This Test Guideline describes a method which is an adaptation of the Soap and Detergent Association semi-continuous activated sludge (SCAS) procedure for assessing the primary biodegradation of alkyl benzene sulphonate. The test does not simulate ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 301: Ready Biodegradability by OECD Pdf
This Test Guideline describes six methods that permit the screening of chemicals for ready biodegradability in an aerobic aqueous medium. The methods are: the DOC Die-Away, the CO2 Evolution (Modified Sturm Test), the MITI (I) (Ministry of ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 302C: Inherent Biodegradability: Modified MITI Test (II) by OECD Pdf
This Test Guideline describes the modified MITI test (II). This test permits the measurement of the Biochemical Oxygen Demand (BOD) and the analysis of residual chemicals in order to evaluate the inherent biodegradability of chemical substances ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 311: Anaerobic Biodegradability of Organic Compounds in Digested Sludge: by Measurement of Gas Production by OECD Pdf
This Test Guideline describes a screening method for the evaluation of potential anaerobic biodegradability of organic chemicals under specific conditions. Washed digested sludge, containing low (
OECD Guidelines for the Testing of Chemicals / Section 3: Degradation and Accumulation Revised Introduction to the OECD Guidelines for Testing of Chemicals by OECD Pdf
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 306: Biodegradability in Seawater by OECD Pdf
This Test Guideline describes two methods for biodegradability in seawater. The shake flask method consists on dissolution of a pre-determined amount of the test substance in the test medium to yield a concentration of 5-40 mg/l dissolved organic ...
Introduction to Toxicological Screening Methods and Good Laboratory Practice by Saravana Babu Chidambaram,M. Mohamed Essa,M. Walid Qoronfleh Pdf
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.
OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fifteenth Addendum - 2004 by OECD Pdf
The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 312: Leaching in Soil Columns by OECD Pdf
The method described in this Test Guideline is based on soil column chromatography in disturbed soil. Two types of experiments are performed to determine (i) the leaching potential of the test substance, and (ii) the leaching potential of ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 317: Bioaccumulation in Terrestrial Oligochaetes by OECD Pdf
This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 309: Aerobic Mineralisation in Surface Water – Simulation Biodegradation Test by OECD Pdf
The purpose of this test is to measure the time course of biodegradation of a test substance at low concentration in aerobic natural water and to quantify the observations in the form of kinetic rate expressions. The test is performed in batch by ...