Oncogenomics And Cancer Proteomics

Author : Cesar Lopez-Camarillo,Elena Arechaga-Ocampo
Publisher : BoD – Books on Demand
Page : 242 pages
File Size : 46,6 Mb
Release : 2013-03-13
Category : Medical
ISBN : 9789535110415

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Oncogenomics and Cancer Proteomics by Cesar Lopez-Camarillo,Elena Arechaga-Ocampo Pdf

Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics and their potential applications in cancer translational research. It is intended for students, scientists, clinicians, oncologists and health professionals working in cancer research.

Author : Charles Brenner,David Duggan
Publisher : John Wiley & Sons
Page : 411 pages
File Size : 44,7 Mb
Release : 2004-11-19
Category : Medical
ISBN : 9780471476641

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Oncogenomics by Charles Brenner,David Duggan Pdf

This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.

Author : William J. LaRochelle,Richard A. Shimkets
Publisher : Springer Science & Business Media
Page : 745 pages
File Size : 49,8 Mb
Release : 2007-11-09
Category : Medical
ISBN : 9781592598939

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The Oncogenomics Handbook by William J. LaRochelle,Richard A. Shimkets Pdf

An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including Ritux an, Erbitux, Gleevec Herceptin, Avastin, ABX-EGF, Velcade, Kepivance, Iressa, Tarceva, and Zevalin are addressed. Highlights include cancer genomics, pharmacogenomics, transcriptomics, gene expression analysis, proteomic and enzymatic cancer profiling technologies, and cellular and animal approaches to cancer target validation.

Author : Franco Dammacco,Franco Silvestris
Publisher : Academic Press
Page : 718 pages
File Size : 51,8 Mb
Release : 2018-10-30
Category : Medical
ISBN : 9780128117866

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Oncogenomics by Franco Dammacco,Franco Silvestris Pdf

Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as diagnostic and prognostic biomarkers for various types of cancers including pancreatic, gastrointestinal, breast, hematological, lung, osteotropic, genitourinary, and skin cancers. This book provides a foundation for clinical oncologists, human geneticists, and physicians to develop new targeted cancer treatments and incorporate genomic medicine into clinical practice, with particular attention paid to noninvasive diagnostic techniques such as the liquid biopsy and molecular characterization of solid malignancies. Provides clinical oncologists, human geneticists, physicians, and students with a thorough understanding of current diagnostic and prognostic applications of genomic methods and technologies to a variety of solid malignancies Employs current knowledge in oncogenomics towards developing therapeutic interventions for various cancer types Features a team of internationally recognized researchers and physicians in clinical oncology, oncogenomics and precision medicine

Author : Eden Dennis
Publisher : Unknown
Page : 0 pages
File Size : 41,5 Mb
Release : 2015-03-09
Category : Electronic
ISBN : 163242066X

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Cancer Genomics and Proteomics by Eden Dennis Pdf

The book focuses on the field of cancer genomics and proteomics. It has been compiled with elaborative reviews of the most general cancers, from bench to bedside applications by an internationally renowned team of veterans and it will certainly contribute to the medical and scientific community by illustrating updated discoveries of oncogenomics and their potential applications in cancer translational research. This comprehensive book aims to serve as a useful resource for clinicians, students, oncologists, scientists and health professionals engaged in cancer research.

Author : Shafat Ali,Sabhiya Majid,Muneeb U. Rehman
Publisher : Elsevier
Page : 414 pages
File Size : 50,6 Mb
Release : 2023-02-14
Category : Science
ISBN : 9780323950732

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Proteomics by Shafat Ali,Sabhiya Majid,Muneeb U. Rehman Pdf

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment. The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice. Provides up-to-date information on current cancer proteomics research developed globally Presents basic research aspects to clinical implications of proteomics on cancer diagnosis and potential treatments Discusses challenges and future developments of the field to leverage further research and applicability in clinical setting

Author : Daniel C. Liebler
Publisher : Wiley-Liss
Page : 220 pages
File Size : 46,8 Mb
Release : 2004
Category : Medical
ISBN : UOM:39015061022847

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Proteomics in Cancer Research by Daniel C. Liebler Pdf

The unique proteomic features that characterize cancers offer new opportunities for disease prevention and treatment. Despite intense interest, however, proteomics is just beginning to become a part of the cancer research mainstream, as relatively few cancer researchers have training in proteomics methods and approaches. This volume covers both the basic principles of proteomics along with detailed presentations of new and emerging technology that represent promising breakthroughs in cancer prevention and treatment.

Author : Suman S. Thakur,Harsha Gowda,D. R. Mani,Bhaswati Chatterjee
Publisher : Frontiers Media SA
Page : 427 pages
File Size : 40,9 Mb
Release : 2022-01-11
Category : Medical
ISBN : 9782889717620

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Proteomics and its Applications in Cancer by Suman S. Thakur,Harsha Gowda,D. R. Mani,Bhaswati Chatterjee Pdf

Author : Sayed S. Daoud
Publisher : Springer Science & Business Media
Page : 263 pages
File Size : 51,5 Mb
Release : 2008
Category : Medical
ISBN : 9781588298584

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Cancer Proteomics by Sayed S. Daoud Pdf

This book covers current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice. It details current technologies used in proteomics, examines the use proteomics in cell signaling, presents clinical applications of proteomics in cancer therapy, and looks at the role of the FDA in regulating the use of proteomics.

Author : Timothy D. Veenstra
Publisher : John Wiley & Sons
Page : 375 pages
File Size : 43,7 Mb
Release : 2013-05-30
Category : Science
ISBN : 9781118634417

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Proteomic Applications in Cancer Detection and Discovery by Timothy D. Veenstra Pdf

Helps researchers in proteomics and oncology work together to understand, prevent, and cure cancer Proteomic data is increasingly important to understanding the origin and progression of cancer; however, most oncologic researchers who depend on proteomics for their studies do not collect the data themselves. As a result, there is a knowledge gap between scientists, who devise proteomic techniques and collect the data, and the oncologic researchers, who are expected to interpret and apply proteomic data. Bridging the gap between proteomics and oncology research, this book explains how proteomic technology can be used to address some of the most important questions in cancer research. Proteomic Applications in Cancer Detection and Discovery enables readers to understand how proteomic data is acquired and analyzed and how it is interpreted. Author Timothy Veenstra has filled the book with examples many based on his own firsthand research experience that clearly demonstrate the application of proteomic technology in oncology research, including the discovery of novel biomarkers for different types of cancers. The book begins with a brief introduction to systems biology, explaining why cancer is a systems biology disease. Next, it covers such topics as: Mass spectrometry in cancer research Application of proteomics to global phosphorylation analysis Search for biomarkers in biofluids Rise and fall of proteomic patterns for cancer diagnostics Emergence of protein arrays Role of proteomics in personalized medicine The final chapter is dedicated to the future prospects of proteomics in cancer research. By guiding readers through the latest proteomic technologies and their applications in cancer research, Proteomic Applications in Cancer Detection and Discovery enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.

Author : Narendra Wajapeyee
Publisher : Humana Press
Page : 0 pages
File Size : 44,9 Mb
Release : 2014-07-17
Category : Medical
ISBN : 1493909916

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Cancer Genomics and Proteomics by Narendra Wajapeyee Pdf

Cancer Genomics and Proteomics: Methods and Protocols, Second Edition includes methods for the analyses of cancer genome and proteome that have illuminated us about the changes in cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Genomics and Proteomics: Methods and Protocols, Second Edition seeks to aid scientists in the further study into various aspects of tumor initiation and progression.

Author : John Masters,Bernhard Ø Palsson
Publisher : Springer Science & Business Media
Page : 293 pages
File Size : 42,9 Mb
Release : 2006-04-11
Category : Medical
ISBN : 9780306468728

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Cancer Cell Lines Part 1 by John Masters,Bernhard Ø Palsson Pdf

Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading.

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Page : 638 pages
File Size : 50,6 Mb
Release : 2013-01-05
Category : Medical
ISBN : 9781627032728

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Applications of Biotechnology in Neurology by Kewal K. Jain Pdf

Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology. Thorough, cutting-edge, and thoughtfully organized, Applications of Biotechnology in Neurology serves as an ideal guide, supplemented by 75 tables and 16 figures as well as numerous references from recent literature on this topic, which are appended to each chapter.

Author : Stella Pelengaris,Michael Khan
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 54,5 Mb
Release : 2009-03-12
Category : Science
ISBN : 9781444309089

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The Molecular Biology of Cancer by Stella Pelengaris,Michael Khan Pdf

This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field

Author : Anonim
Publisher : ScholarlyEditions
Page : 1148 pages
File Size : 41,5 Mb
Release : 2013-05-01
Category : Medical
ISBN : 9781490108827

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Issues in Cancer Epidemiology and Research: 2013 Edition by Anonim Pdf

Issues in Cancer Epidemiology and Research / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Oncology Research. The editors have built Issues in Cancer Epidemiology and Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Oncology Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Epidemiology and Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.