Author : Edward Chu, M.D.
Publisher : Unknown
Page : 546 pages
File Size : 44,7 Mb
Release : 2006-05-04
Category : Medical
ISBN : 0763741590
Oncomd 2006
Edward Chu, M.D.
Oncomd 2006
Oncomd 2006 Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Oncomd 2006 book. This book definitely worth reading, it is an incredibly well-written.
Proceedings of the Board of Regents
University of Michigan. Board of Regents
Author : University of Michigan. Board of Regents
Publisher : UM Libraries
Page : 470 pages
File Size : 41,6 Mb
Release : 2024-05-17
Category : Electronic
ISBN : UOM:39015071494762
Proceedings of the Board of Regents by University of Michigan. Board of Regents Pdf
Cancer Stem Cells
Lucie Laplane
Author : Lucie Laplane
Publisher : Harvard University Press
Page : 237 pages
File Size : 53,7 Mb
Release : 2016-06-06
Category : Science
ISBN : 9780674969568
Cancer Stem Cells by Lucie Laplane Pdf
A new therapeutic strategy could break the stalemate in the war on cancer by targeting not all cancerous cells but the small fraction that lie at the root of cancers. Lucie Laplane offers a comprehensive analysis of cancer stem cell theory, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy.
Introduction to Biological and Small Molecule Drug Research and Development
C. Robin Ganellin,Roy Jefferis,Stanley M. Roberts
Author : C. Robin Ganellin,Roy Jefferis,Stanley M. Roberts
Publisher : Academic Press
Page : 472 pages
File Size : 40,9 Mb
Release : 2013-05-07
Category : Science
ISBN : 9780123977700
Introduction to Biological and Small Molecule Drug Research and Development by C. Robin Ganellin,Roy Jefferis,Stanley M. Roberts Pdf
Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry. For the first time, the fundamental scientific principles of biopharmaceuticals and small molecule chemotherapeutics are discussed side-by-side at a basic level Edited by three senior scientists with over 100 years of experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development
DIRECTORY OF CORPORATE COUNSEL.
Anonim
Author : Anonim
Publisher : Wolters Kluwer Law & Business
Page : 4772 pages
File Size : 44,6 Mb
Release : 2023
Category : Electronic
ISBN : 9781543879414
DIRECTORY OF CORPORATE COUNSEL. by Anonim Pdf
Systems Biology of Cancer
Sam Thiagalingam
Author : Sam Thiagalingam
Publisher : Cambridge University Press
Page : 597 pages
File Size : 54,9 Mb
Release : 2015-04-09
Category : Mathematics
ISBN : 9780521493390
Systems Biology of Cancer by Sam Thiagalingam Pdf
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Highlights of Progress in Research on Cancer
Anonim
Author : Anonim
Publisher : Unknown
Page : 72 pages
File Size : 48,5 Mb
Release : 1960
Category : Cancer
ISBN : MINN:319510004251884
Highlights of Progress in Research on Cancer by Anonim Pdf
Global Strategy
Vinod K. Jain
Author : Vinod K. Jain
Publisher : Routledge
Page : 321 pages
File Size : 50,7 Mb
Release : 2016-07-15
Category : Business & Economics
ISBN : 9781317549307
Global Strategy by Vinod K. Jain Pdf
Global Strategy: Competing in the Connected Economy details how firms enter, compete and grow in foreign markets. Jain moves away from the traditional focus on developed countries and their multinational enterprises, instead focusing on both developed and emerging economies, as well as their interaction in an increasingly connected world. As the current global business environment is increasingly shaped—and connected—by faster technological developments, geopolitical forces, emerging economies, and new multinationals from those economies, this highly charged dynamic provides rich opportunity to revisit mainstream paradigms in globalization, innovation, and global strategy. The book rises to the challenge, exploring new competitive phenomena, new business models, and new strategies. Rich illustrations, real-world examples, and case data, provide students and executives with the insights necessary to connect, compete, and grow in a globalized business environment. This bold book succinctly covers strategy models and implementation for a range of global players, providing students of strategy and international business with a rich understanding of the contemporary business environment. For access to additional materials, including Powerpoint slides, a list of suggested cases, and sample syllabus, please contact Vinod Jain ([email protected]).
Breast Cancer Stem Cells & Therapy Resistance
Phuc Van Pham
Author : Phuc Van Pham
Publisher : Springer
Page : 114 pages
File Size : 53,8 Mb
Release : 2015-11-26
Category : Science
ISBN : 9783319220208
Breast Cancer Stem Cells & Therapy Resistance by Phuc Van Pham Pdf
This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters introduce and compare stem cells and cancer stem cells, describe properties and isolation techniques of BCSCs, and examine BCSC-targeting approaches. The text concludes with a discussion of controversy surrounding the BCSC hypothesis and of future research directions. Breast Cancer Stem Cells & Therapy Resistance, part of the SpringerBriefs in Stem Cells series, provides a succinct yet comprehensive overview of BCSCs for advanced students, graduate students and researchers as well as those working with breast cancer or stem cells in a clinical setting.
MSC Communication in Physiological and Pathological Settings
Philippe Bourin,Louis Casteilla,Jeffrey Gimble,Antonio Salgado
Author : Philippe Bourin,Louis Casteilla,Jeffrey Gimble,Antonio Salgado
Publisher : Frontiers Media SA
Page : 138 pages
File Size : 42,7 Mb
Release : 2022-08-22
Category : Science
ISBN : 9782889768035
MSC Communication in Physiological and Pathological Settings by Philippe Bourin,Louis Casteilla,Jeffrey Gimble,Antonio Salgado Pdf
Dr. Bourin works in a biotechnology company that develops a production process of ASC for clinical uses. Dr. Gimble is a co-founder, co-owner, and Chief Scientific Officer at Obatala Sciences and LaCell, biotechnology companies focused on the clinical translation of adipose-derived cells and tissues. The other Guest Editors declare no competing interests with regard to the Research Topic subject.
Science
John Michels (Journalist)
Author : John Michels (Journalist)
Publisher : Unknown
Page : 864 pages
File Size : 40,8 Mb
Release : 2005
Category : Science
ISBN : IND:30000146536259
Science by John Michels (Journalist) Pdf
A weekly record of scientific progress.
In Sight
Julia Levy
Author : Julia Levy
Publisher : University of Toronto Press
Page : 307 pages
File Size : 51,8 Mb
Release : 2020-10-01
Category : Biography & Autobiography
ISBN : 9781487537999
In Sight by Julia Levy Pdf
In Sight is a memoir about how a love of science and discovery drove Julia Levy, a celebrated scholar and biotech CEO, to work her way through gender bias in order to achieve academic and professional recognition. Her story traces the unconventional invention of a breakthrough drug treatment from its development from laboratory research to its application as a medical treatment for vision loss. Told from a female perspective, In Sight is a unique and personal story covering Levy’s early years as a refugee, her university training in the UK, and her appointment as professor at the University of British Columbia. Years spent as an academic led the author to unexpected exposure to the biotechnology industry and a chance meeting with colleagues that led to the formation of a lucrative biotechnology company, known today as QLT Inc. The bulk of the book covers the years spent building the company, and Levy’s surprising transition from chief scientific officer to CEO. In Sight is an honest description of the trials of drug development, the tensions inherent in the commercialization of health innovations, and the truly remarkable hurdles faced by women in the scientific community.
Clinical Research Monitoring: A European Approach
Van Dooren A A
Author : Van Dooren A A
Publisher : World Scientific
Page : 536 pages
File Size : 43,7 Mb
Release : 2017-09-21
Category : Medical
ISBN : 9789813223196
Clinical Research Monitoring: A European Approach by Van Dooren A A Pdf
Clinical research monitoring is a vital aspect of Good Clinical Practice (GCP). Its principles are straightforward: they are aimed at protecting those subjects that participate in the trial, and their goal is to provide reliable data that will contribute to the safety and efficacy of the intervention under study, i.e. to support the health of future subjects. However, the practical implementation of these major goals is complicated. Various mishaps have happened in recent history, and an extensive set of international rules and regulations have emerged. This book gives a thorough survey of the ethical and legal aspects of clinical research and provides a detailed guideline for implementing these aspects into the practice of studying investigational medicinal products in humans, in the European context. It can be used as a study aid for starting monitors, a reference guide for more experienced monitors, and anyone else involved in clinical research. Contents: The PastMedicinal Products: The Development ProcessClinical Trials: Design AspectsThe Rules and the RegsThe Ethical Pillars of Clinical ResearchThe Players Part I: Ethics Committee and Data Monitoring CommitteeThe Players Part II: The Sponsor and the Clinical Research OrganisationThe Players Part III: The Investigator, the Sub-Investigator and the Clinical Research CoordinatorThe Players Part IV: The Pharmacy and the Clinical LaboratoryThe Players Part V: The Subject or PatientSafety Assessment and MonitoringThe VisitsThe Essential Documents Part I: Before Study StartThe Essential Documents Part II: During Trial ConductThe Essential Documents Part III: After Completion or Termination of the TrialData ManagementA Special Case: Medical DevicesComplianceThe Challenge of MonitoringThe Future of Clinical Trial Monitoring — Some Afterthoughts Readership: Clinical research monitors, clinical research associates, trial monitors, clinical research sponsors, contract research organizations (CROs), ethics committees, clinical investigators, and study nurses. Keywords: Clinical Research;Monitoring;CRA;GCP;Clinical Trials;Drug Development;Investigational Medicinal Products (IMPs)Review: Key Features: Current textbooks are US (FDA)-based, but this book covers the European situationProvides an up-to-date review of the theoretical and practical basis of clinical research monitoring and GCP, including the latest International Council for Harmonisation (ICH) GCP revisionsThe author has more than 10 years of experience in training and education of clinical research monitors
Tumor Angiogenesis
Sophia Ran
Author : Sophia Ran
Publisher : BoD – Books on Demand
Page : 310 pages
File Size : 43,8 Mb
Release : 2012-02-17
Category : Medical
ISBN : 9789535100096
Tumor Angiogenesis by Sophia Ran Pdf
Tumor angiogenesis is the main process responsible for the formation of new blood vessels that promote tumor growth and metastasis. This process is driven by potent pro-angiogenic factors that are predominant in the tumor environment and are produced by both malignant cells and the host cells recruited to the tumor site. Tumor environment is characterized by the imbalance between pro-angiogenic and anti-angiogenic factors, which drives the construction of numerous but structurally defective vessels. These poorly perfused and abnormal vessels significantly contribute to the tumor pathology not only by supporting the expansion of the tumor mass but also by promoting chronic inflammation, enhancing thrombosis, impeding drug delivery, and disseminating tumor cells. These problems associated with tumor vasculature continue to attract great attention of scientists and clinicians interested in advancing the understanding of tumor biology and development of new drugs. This book complies a series of reviews that cover a broad spectrum of current topics related to the pathology of tumor blood vessels including mechanisms inducing new vessels, identification of new targets for inhibition of tumor angiogenesis, and potential clinical use of known and novel anti-angiogenic therapies. The book provides an update on tumor angiogenesis that could be useful for oncologists, cancer researchers and biologists with interests in vascular and endothelial cell behavior in the context of cancer.
Cancer Stem Cells
Huiping Liu,Justin Durla Lathia
Author : Huiping Liu,Justin Durla Lathia
Publisher : Elsevier
Page : 542 pages
File Size : 45,6 Mb
Release : 2016-08-16
Category : Science
ISBN : 9780128039342
Cancer Stem Cells by Huiping Liu,Justin Durla Lathia Pdf
Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical trials to target cancer stem cells, remove the roots of cancer, eliminate the seeds of metastasis, overcome the resistance of therapies, and contribute to the eradication of cancer. The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies. Provides an authoritative and complete overview of cancer stem cells Includes comprehensive coverage of current therapeutic strategies targeting cancer stem cells Deepens a reader’s technical expertise in cancer stem cell biology