Opening Doors Joan Steitz And Jennifer Doudna Of The Rna World
Opening Doors Joan Steitz And Jennifer Doudna Of The Rna World Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Opening Doors Joan Steitz And Jennifer Doudna Of The Rna World book. This book definitely worth reading, it is an incredibly well-written.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
Cool Biology Activities for Girls by Laura Christine Lewandowski Pdf
Get your science groove on, and check out these awesome biology projects: Flowers that color themselves, Tricks that confuse the brain, Taking DNA from a banana. Biology is easy when you're having this much fun!
Structural Insights Into Gene Expression And Protein Synthesis by Thomas A Steitz Pdf
Several years ago, Thomas Steitz agreed to contribute a volume to the 'World Scientific Series in Structural Biology' that would deal with the contributions he and his coworkers have made to structural biology during his remarkable career. Sadly, Tom died in the fall of 2018 before he had had time to do more than produce an outline for this book, and a list of the reprints he wanted it to contain.Fortunately, Tom's colleagues and coworkers responded enthusiastically when they were informed later that fall that if they were willing to help out, a volume would be published to commemorate his career. It fell to Anders Liljas, Peggy Eatherton, Tom's longtime administrative assistant, and Peter Moore, a close colleague, to oversee their efforts. Thomas Steitz is best known for the work he and his coworkers did to elucidate the biochemical basis of gene expression. The structures of a large number of the macromolecules involved in transcription and translation emerged from his laboratory over the course of his career. This book includes reprints of the most important papers he had published, grouped according to the structures they relate to, and commentaries written by the scientists who collaborated with him to solve each of them. It thus summarizes the achievements of one of the most distinguished biochemists of the second half of the 20th century.
The Wise Advocate by Art Kleiner,Josie Thomson,Jeffrey Schwartz Pdf
Leadership is the habit of making good choices. Even in difficult and uncertain circumstances, the most effective leaders focus their attention and overcome entrenched patterns of behavior to push an organization to new heights of success. This capability is no fluke: the latest research on the brain shows that we can pinpoint the mental activity associated with it—and cultivate it for our benefit. In this book, Art Kleiner, a strategy expert; Jeffrey Schwartz, a research psychiatrist; and Josie Thomson, an executive coach, give a transformative explanation of how cutting-edge neuroscience can help business leaders set a course toward better management. Mapping the functions of a manager onto established patterns of mental activity, they identify crucial brain circuits and their parallels in organizational culture. Strategic leaders, they show, play the role of wise advocates: able to go beyond day-to-day transactional behavior to a longer-term, broader perspective that articulates their organization’s deeper purpose. True leaders can play this influencer role in an organization because they have cultivated similar self-reflective habits in their own minds. Providing a powerful guide to decision strategies and their consequences, The Wise Advocate helps managers find their own inner voice and then make that voice ring out loud and clear, with a four-step program for practice and catalytic implications for management strategy, executive education, and business results.
Galaxies and Cosmology by Francoise COMBES,Patrick Boissé,Alain Mazure,Alain Blanchard Pdf
Unique in its breadth of coverage and level of presentation, this revised textbook provides more on the nature of galaxies, extragalactic objects, the large-scale structure of the Universe, and cosmology than is available in general textbooks on astronomy. It remains, however, accessible to advanced undergraduate students. One or more chapters are devoted to each of the following: the classification and morphology of galaxies; the galactic interstellar medium; galactic kinematics; elliptical, spiral, and barred spiral galaxies; the interactions between galaxies; extragalactic radio sources, quasars and their line spectra, and other active galactic nuclei; the formation of galaxies; the Universe as a whole; and cosmology.
National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Committee on Responsible Science
Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Committee on Responsible Science Publisher : National Academies Press Page : 327 pages File Size : 44,8 Mb Release : 2018-01-13 Category : Science ISBN : 9780309391252
Fostering Integrity in Research by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Committee on Responsible Science Pdf
The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.
Biomedical and Environmental Sensing by J. I. Agbinya,E. Biermann,Y. Hamam Pdf
At a time when the applications of sensors are in high demand and environmental issues are international priorities, this book on biomedical and environmental sensing provides the technical basis for researchers and students to understand the requirements for biomedical computing and also environmental sensing and to develop solutions in their areas of interests. The book deals with key techniques that need to be understood and also examples of applications of the techniques. Biomedical and environmental sensing are helping to extend the life span of human beings and infrastructures as it has become more and more sensible to understand what is happening for example inside a person, an aircraft, a road network or a bridge and to provide quick response.Several chapters of the book have dealt with the state of the art in biomedical decision support systems in therapeutic medicine. A data driven decision support system and a prototype support system for anaesthetics are major enablers for doctors and nurses to provide efficient and timely response not only to diagnose ailments but also to decide on the preferred approach for solving the problems. The analyses in the chapters are coherently detailed and easy to comprehend. There is a chapter on hypothermia therapy and a hardware probe was also developed and described. Classification of chromosomes is a major aid in DNA analysis and recognition. This valuable insight into a DNA analysis method is provided. Information on heart diseases, onset of heart attacks and failure can be detected through reconstructing electrophysiological information about the surface of the heart. A reconstruction method is described in this book and provides strong foundation for research and training in this life determining area. The remaining chapters on sensing of driver conditions including fatigue peeks into tools and methodologies for understanding both the onset of fatigue and its forms for prevention of accidents in vehicles. The rest of the book gives techniques for planning biomedical and environmental sensor networks and their security. The book will no doubt greatly serve the needs of health professionals, researchers in the health and environmental industry and policy makers.
RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications by Naoyuki Kataoka,Akila Mayeda,Kinji Ohno Pdf
This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications. In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.
he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pathology of inherited disease and viral infection. This volume seeks to review the rapid progress being made in the study of how mRNA precursors are processed into mRNA and to convey the broad scope of the RNA field and its relevance to other areas of cell biology and medicine. Since one of the major themes of RNA processing is the recognition of specific RNA sequences and structures by protein factors, we begin with reviews of RNA-protein interactions. In chapter 1 David Lilley presents an overview of RNA structure and illustrates how the structural features of RNA molecules are exploited for specific recognition by protein, while in chapter 2 Maurice Swanson discusses the structure and function of the large family of hnRNP proteins that bind to pre-mRNA. The next four chapters focus on pre-mRNA splicing.