Proteins And Nucleic Acids

Author : J. Andrew McCammon,Stephen C. Harvey
Publisher : Cambridge University Press
Page : 256 pages
File Size : 52,5 Mb
Release : 1988-04-29
Category : Science
ISBN : 0521356520

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Dynamics of Proteins and Nucleic Acids by J. Andrew McCammon,Stephen C. Harvey Pdf

This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.

Author : Robert F. Steiner,Ira Weinryb
Publisher : Springer
Page : 512 pages
File Size : 44,6 Mb
Release : 1971-08
Category : Science
ISBN : UOM:39015004342625

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Excited States of Proteins and Nucleic Acids by Robert F. Steiner,Ira Weinryb Pdf

The choice of title for this collective volume reflects the desire of the editors and authors to make clear that, while the bulk of the material is concerned with luminescence, other aspects of the excited state have not been excluded. In the five years which have elapsed since the publication of the classical monograph of Konev, a wealth of new information has ap peared on the emission properties of proteins and nucleic acids. Indeed, since new publications in this area appear to be proliferating in a geometric ratio, this may be the last opportunity to provide a comprehensive summary of the field in a book which is not of prohibitive length. This is what we have attempted to do here. While the orientation of each chapter naturally reflects the interests and point of view of the author, there has been a general effort to present .a critical assessment of existing results and interpretations, rather than a compendium of data with minimal comment. Finally, it should be stressed that the rapid evolution of the subject at the time of writing makes it inevitable that the book will age to some degree over the next few years, although this will occur at differing rates for the various chapters. We can only hope that most of the material in this interim summing-up will prove resistant to the erosion of time and provide a solid foundation for further progress.

Author : Lev Abramovich Osterman
Publisher : Springer
Page : 528 pages
File Size : 44,6 Mb
Release : 1984
Category : Science
ISBN : UOM:39015012556976

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Methods of Protein and Nucleic Acid Research by Lev Abramovich Osterman Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 40,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Phoebe A. Rice,Carl C. Correll
Publisher : Royal Society of Chemistry
Page : 417 pages
File Size : 48,7 Mb
Release : 2008-05-22
Category : Science
ISBN : 9780854042722

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Protein-Nucleic Acid Interactions by Phoebe A. Rice,Carl C. Correll Pdf

This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.

Author : Abraham Marcus
Publisher : Elsevier
Page : 673 pages
File Size : 47,6 Mb
Release : 2014-05-10
Category : Science
ISBN : 9781483220369

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Proteins and Nucleic Acids by Abraham Marcus Pdf

The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information. This book presents the processes by which the nucleic acids are finally expressed as proteins. Organized into 14 chapters, this volume begins with an overview of the overall structure of eukaryotic genomes, with emphasis on higher-plant DNA. This text then examines the enzymes involved in the cleavage and degradation of DNA. Other chapters provide a critical assessment of eukaryotic nucleic acid polymerases. This book discusses as well some examples from plant mitochondrial systems. The final chapter deals with two special areas of plant biology where the expression of the nucleic acids is seen in striking relief, the formation of plant tumors, and the growth and expression of plant viruses. This book is a valuable resource for plant biochemists, molecular biologists, senior graduate students, and research workers.

Author : E. Clementi,S. Chin
Publisher : Springer Science & Business Media
Page : 454 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468453089

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Structure and Dynamics of Nucleic Acids, Proteins, and Membranes by E. Clementi,S. Chin Pdf

This volume collects a number of the invited lectures and a few selected contrib utions presented at the International Symposium on Structure and Dynamics of Nucleic Acids, Proteins and Membranes held August 31st through September 5th, 1986, in Riva del Garda, Italy. The title of the conference as well as a number of the topics covered represent a continuation of two previous conferences, the first held in 1982 at the University of California in San Diego, and the second in 1984 in Rome at the Accademia dei Lincei. These two earlier conferences have been documented in Structure and Dynamics: Nucleic Acids and Proteins, edited by E. Clementi and R. H. Sarma, Adenine Press, New York, 1983, and Structure and Motion: Membranes, Nucleic Acids and Proteins, edited by E. Clementi, G. Corongiu, M. H. Sarma and R. H. Sarma, Adenine Press, New York, 1985. At this conference in Riva del Garda we were very hesitant to keep the name of the conference the same as the two previous ones. Indeed, a number of topics discussed in this conference were not included in the previous ones and even the emphasis of this gathering is only partly reflected in the conference title. An alternative title would have been Structure and Dynamics of Nucleic Acids, Proteins, and Higher Functions, or, possibly, "higher components" rather than "higher functions.

Author : Ram I. Mahato
Publisher : CRC Press
Page : 708 pages
File Size : 51,6 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9780203492321

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Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids by Ram I. Mahato Pdf

Newcomers to the field of biopharmaceuticals require an understanding of the basic principles and underlying methodology involved in developing protein- and nucleic acid-based therapies for genetic and acquired diseases. Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids introduces the principles of polymer science and che

Author : Gerald D. Fasman,Serge N. Timasheff
Publisher : Unknown
Page : 460 pages
File Size : 47,7 Mb
Release : 1970
Category : Science
ISBN : UOM:39015015993754

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Fine Structure of Proteins and Nucleic Acids by Gerald D. Fasman,Serge N. Timasheff Pdf

Author : Ruth Porter,Maeve O'Connor,Julie Whelan
Publisher : John Wiley & Sons
Page : 192 pages
File Size : 41,8 Mb
Release : 2009-09-14
Category : Science
ISBN : 9780470718445

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Mobility and Function in Proteins and Nucleic Acids by Ruth Porter,Maeve O'Connor,Julie Whelan Pdf

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Author : F. Korte
Publisher : Elsevier
Page : 240 pages
File Size : 54,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323159432

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Nucleic Acids, Proteins and Carbohydrates by F. Korte Pdf

Methodicum Chimicum, Volume 11: Natural Compounds, Part 1: Nucleic acids, Proteins and Carbohydrates is devoted to the methods of structural determinations and syntheses of natural products. This text contains four chapters that include a short discussion of the principles of well-proved analytic procedures. It primarily describes the chemistry and biochemistry of nucleic acids, proteins, carbohydrates, and lipids. Other general topics covered include the components, chemical synthesis, sequences, primary structure, and classification of these macromolecules. This book is of value to chemists and scientists who works in associated areas, including medicine.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Computer-Assisted Modeling
Publisher : National Academies Press
Page : 186 pages
File Size : 49,5 Mb
Release : 1987-02-01
Category : Computers
ISBN : 9780309062282

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Computer Assisted Modeling by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Computer-Assisted Modeling Pdf

In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the polymers are capable of both inter- and intramolecular interactions. These interactions confer upon the polymers distinctive three-dimensional shapes. These tertiary configurations, in turn, determine the function of the macromolecule. Computers have become so inextricably involved in empirical studies of three-dimensional macromolecular structure that mathematical modeling, or theory, and experimental approaches are interrelated aspects of a single enterprise.

Author : A. D. McLaren,D. Shugar
Publisher : Elsevier
Page : 462 pages
File Size : 54,8 Mb
Release : 2016-06-06
Category : Science
ISBN : 9781483136035

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Photochemistry of Proteins and Nucleic Acids by A. D. McLaren,D. Shugar Pdf

Photochemistry of Proteins and Nucleic Acids focuses on the effects of ultraviolet and visible radiations on proteins and nucleic acids. The book first discusses some principles of photochemistry, including the laws of photochemistry and factors influencing photochemical reactions in solutions. The text describes absorption and luminescence spectra of nucleoproteins and their components, including principal absorbing groups in proteins, nucleic acids, and nucleoproteins. The selection also highlights the action of ultraviolet light on proteins; photochemical and photosensitized inactivation of enzymes; and the photochemistry of purine and pyrimidine derivatives. The text also discusses nucleic acids and oligo- and polynucleotides. Topics include photochemical degradation of nucleic acid; kinetics of biological inactivation of nucleic acids; nucleoproteins; and reversibility of nucleic acid photolysis. The book also encompasses the inactivation of viruses, including inactivation studies with a plant virus, bacteriophages, and photochemically produced vaccines. The text also presents some problems in photobiology and some techniques in photochemistry. The text is a good source of information for readers interested in the study of proteins and nucleic acids. Based on the standards and codes from Fo

Author : D. Boulter
Publisher : Springer
Page : 770 pages
File Size : 49,6 Mb
Release : 2011-12-06
Category : Science
ISBN : 3642682383

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Nucleic Acids and Proteins in Plants I by D. Boulter Pdf

D. BOULTER and B. PARTHIER At the time of the former edition of the Encyclopedia of Plant Physiology, approximately 25 years ago, no complete plant protein amino acid sequences or nucleic acid sequences had been determined. Although the structure of DNA and its function as the genetic material had just been reported, little detail was known of the mechanism of its action, and D. G. CATCHSIDE was to write in the first chapter of the first volume of the Encyclopedia: "There is a consider able body of evidence that the gene acts as a unit of physiological action through the control of individual enzymes". No cell-free transcription and pro tein-synthesizing systems were available and the whole range of powerful meth ods of recombinant DNA technology was still to be developed. Today for the first time with plant systems, it is possible not only to describe their molecular biology but also to manipulate it, i. e. , to move from a description to a technological phase. The properties of living systems are inscribed by those of the proteins and nucleic acids which they synthesize. Proteins, due to their very large size, occur as macromolecules in colloidal solution or associated in supra-molecular colloi dal form. The colloidal state confers low thermal conductivity, low diffusion coefficients and high viscosity, properties which buffer a biological system from the effects of a changing environment. Biological systems not only have great stability, but also the capacity to reproduce.

Author : E. Palecek,F. Scheller,J. Wang
Publisher : Elsevier
Page : 809 pages
File Size : 50,7 Mb
Release : 2005-12-19
Category : Science
ISBN : 9780080457451

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Electrochemistry of Nucleic Acids and Proteins by E. Palecek,F. Scheller,J. Wang Pdf

DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century. * Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins * Summarises the present state of electrochemical analysis of nucleic acids and proteins * Includes future trends in the electrochemical analysis in genomics and proteomics