Optimization And Applicability Of Bioprocesses Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Optimization And Applicability Of Bioprocesses book. This book definitely worth reading, it is an incredibly well-written.
Optimization and Applicability of Bioprocesses by Hemant J. Purohit,Vipin Chandra Kalia,Atul N. Vaidya,Anshuman A. Khardenavis Pdf
This book argues that the sustainable management of resources requires a systematic approach that primarily involves the integration of green innovative biotechnological strategies and eco-engineering. It discusses how microbial community intelligence can be used for waste management and bio-remediation and explains how biological processes can be optimized by integrating genomics tools to provide perspectives on sustainable development. The book describes the application of modern molecular techniques such as fluorescence in situ hybridization (FISH), highly sensitive catalyzed reporter deposition (CARD)-FISH, in situ DNA-hybridization chain reaction (HCR) and methods for detecting mRNA and/or functional genes to optimize bioprocessess. These techniques, supplemented with metagenomic analysis, reveal that a large proportion of micro-organisms still remain to be identified and also that they play a vital role in establishing bioprocesses.
Digital Twins by Christoph Herwig,Ralf Pörtner,Johannes Möller Pdf
This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.
Control in Bioprocessing by Pablo A. López Pérez,Ricardo Aguilar López,Ricardo Femat Pdf
Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing "quality" of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses.
Digital Twins by Christoph Herwig,Ralf Pörtner,Johannes Möller Pdf
This is the first of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book explains the mathematical structure of digital twins, their development and the model’s respective parts, as well as concepts for the knowledge-driven generation and structural variability of digital twins. Covering fundamentals as well as applications, the two volumes offer the ideal introduction to the topic for researchers in academy and industry alike.
Post Treatments of Anaerobically Treated Effluents by Vinay Kumar Tyagi,Abid Ali Khan,Ng Wun Jern,Anwar Khursheed,A. A. Kazmi Pdf
The anaerobic process is considered to be a sustainable technology for organic waste treatment mainly due to its lower energy consumption and production of residual solids coupled with the prospect of energy recovery from the biogas generated. However, the anaerobic process cannot be seen as providing the ‘complete’ solution as its treated effluents would typically not meet the desired discharge limits in terms of residual carbon, nutrients and pathogens. This has given impetus to subsequent post treatment in order to meet the environmental legislations and protect the receiving water bodies and environment. This book discusses anaerobic treatment from the perspective of organic wastes and wastewaters (municipal and industrial) followed by various post-treatment options for anaerobic effluent polishing and resource recovery. Coverage will also be from the perspective of future trends and thoughts on anaerobic technologies being able to support meeting the increasingly stringent disposal standards. The resource recovery angle is particularly interesting as this can arguably help achieve the circular economy. It is intended the information can be used to identify appropriate solutions for anaerobic effluent treatment and possible alternative approaches to the commonly applied post-treatment techniques. The succeeding discussion is intended to lead on to identification of opportunities for further research and development. This book can be used as a standard reference book and textbook in universities for Master and Doctoral students. The academic community relevant to the subject, namely faculty, researchers, scientists, and practicing engineers, will find the book both informative and as a useful source of successful case studies.
Optimal Control: New Trends in Applications to Bioprocesses aims to bridge the gap between mathematical optimization methods to solve problems in dynamical systems and bioprocess modeling which involves various techniques to build mathematical models for applications in the bio-production of chemical and pharmaceutical products, covering different length and time scales, from single cells, to cell population, to bioreactors. The two fields are natural partners, however there is a disconnect and literature gap between the mathematical theory of optimal control and the optimization of systems arising in the field of bioprocesses engineering. Provides optimal control techniques applicable to bioprocessing and biotechnology Includes application to waste water treatment, bio-gas optimization and bioremediation problems Presents case studies from real-world examples
Emerging Research in Science and Engineering Based on Advanced Experimental and Computational Strategies by Felipe de Almeida La Porta,Carlton A. Taft Pdf
In this book, the authors discuss some of the main challenges and new opportunities in science and engineering research, which involve combining computational and experimental approaches as a promising strategy for arriving at new insights into composition–structure–property relations, even at the nanoscale. From a practical standpoint, the authors show that significant improvements in the material/biomolecular foresight by design, including a fundamental understanding of their physical and chemical properties, are vital and will undoubtedly help us to reach a new technological level in the future.
A Sustainable Revolution by Idiano D’Adamo,Pasquale Marcello Falcone ,Michael Martin,Paolo Rosa Pdf
The parties of the United Nations Framework Convention on Climate Change (UNFCCC) attained the Paris Agreement to tackle climate change and to strengthen the actions required for a sustainable transition towards an environmentally friendly future. This transition will involve holistic approaches and multifaceted societal shifts, requiring answers and collaboration between private, public, and academic sectors. This book gathers together contributions which study the transition towards a more sustainable future, involving and identifying the development and implications of more sustainable alternatives, in collaboration with all relevant stakeholders (e.g. communities, firms, policy makers, researchers, etc.), to achieve this transition. The approaches proposed are all concerned with a common perspective: imaging our globe with a greener picture, built upon a transversal sustainable revolution to clean up the Earth.
European Perspectives on Green Biotechnology Business Practices by Daniela Zirra,Radu Cristian Toma Pdf
Many interesting publications can be found in the field of green biotechnology entrepreneurship, but most of them focus either on entrepreneurship in biotechnologies in general, or address industries that could benefit from the innovations brought about by green biotech. This book is a European approach to the subject, that starts from concepts and principles and moves to specific elements, promotion and management, financial aspects, achieved economic performances, information technology and communication tools that can be used for the initiation and development of a businesses in this sector, all the way up to a brief mapping of some good practices in different European countries. The book will be of interest to a wide range of readers, such as all those interested in starting and developing a business in this field, and also those who just wish to gather green biotech entrepreneurial knowledge, and to develop their skills and competencies in sustainable development.
Zero Waste: Management Practices for Environmental Sustainability by Ashok K. Rathoure Pdf
Zero Waste: Management Practices for Environmental Sustainability presents approaches for resource management centered on reducing waste and reusing and recycling materials. It aims to save energy by reducing energy consumption associated with extracting, processing, and transporting raw materials and waste, and also to reduce and eventually eliminate the need for landfills and incinerators. This book presents the various principles, methods, and tools that can be used to address different issues in the areas of industrial waste reduction and sustainability. It examines how to eliminate waste at the source and at all points of a supply chain, and how to shift from the current one-way linear resource model to a sustainable "closed-loop" system. Proposes strategies for businesses to reduce and reuse waste with a goal of reaching a zero waste status. Focuses on how mitigating waste and promoting recycling can save vast amounts of energy. Explains how the zero waste approach would be a key measure to ensure environmental sustainability and help to offset global climate change.
Food Waste to Valuable Resources by Rajesh Banu,Gopalakrishnan Kumar,Gunasekaran M.,Kavitha S. Pdf
Food Waste to Valuable Resources: Applications and Management compiles current information pertaining to food waste, placing particular emphasis on the themes of food waste management, biorefineries, valuable specialty products and technoeconomic analysis. Following its introduction, this book explores new valuable resource technologies, the bioeconomy, the technoeconomical evaluation of food-waste-based biorefineries, and the policies and regulations related to a food-waste-based economy. It is an ideal reference for researchers and industry professionals working in the areas of food waste valorization, food science and technology, food producers, policymakers and NGOs, environmental technologists, environmental engineers, and students studying environmental engineering, food science, and more. Presents recent advances, trends and challenges related to food waste valorization Contains invaluable knowledge on of food waste management, biorefineries, valuable specialty products and technoeconomic analysis Highlights modern advances and applications of food waste bioresources in various products’ recovery
Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up Discusses the significance of these life sciences in defining optimum bioprocess performance
Integrated Bioprocess Engineering by Clemens Posten Pdf
Bioprocess engineering employs microorganisms to produce biological products for medical and industrial applications. The book covers engineering tasks around- the cultivation process in bioreactors including media design, feeding strategies, or cell harvesting. All aspects are described from the conceptual considerations to technical realization and provide insight by detailed explanations, drawings, formulas, and example processes.
Development of Sustainable Bioprocesses by Elmar Heinzle,Arno P. Biwer,Charles L. Cooney Pdf
Bioprocess technology involves the combination of living matter (whole organism or enzymes ) with nutrients under laboratory conditions to make a desired product within the pharmaceutical, food, cosmetics, biotechnology, fine chemicals and bulk chemicals sectors. Industry is under increasing pressure to develop new processes that are both environmentally friendly and cost-effective, and this can be achieved by taking a fresh look at process development; - namely by combining modern process modeling techniques with sustainability assessment methods. Development of Sustainable Bioprocesses: Modeling and Assessment describes methodologies and supporting case studies for the evolution and implementation of sustainable bioprocesses. Practical and industry-focused, the book begins with an introduction to the bioprocess industries and development procedures. Bioprocesses and bioproducts are then introduced, together with a description of the unit operations involved. Modeling procedures, a key feature of the book, are covered in chapter 3 prior to an overview of the key sustainability assessment methods in use (environmental, economic and societal). The second part of the book is devoted to case studies, which cover the development of bioprocesses in the pharmaceutical, food, fine chemicals, cosmetics and bulk chemicals industries. Some selected case studies include: citric acid, biopolymers, antibiotics, biopharmaceuticals. Supplementary material provides hands-on materials so that the techniques can be put into practice. These materials include a demo version of SuperPro Designer software (used in process engineering) and models of all featured case studies, excel sheets of assessment methods, Monte Carlo simulations and exercises. Previously available on CD-ROM, the supplementary material can now be accessed via http://booksupport.wiley.com by entering the author name, book title or isbn and clicking on the desired entry. This will then give a listing of all the content available for download. Please read any text files before downloading material.
