Organ Donation And Transplantation

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Opportunities for Organ Donor Intervention Research

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Issues in Organ Donor Intervention Research
Opportunities for Organ Donor Intervention Research Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Issues in Organ Donor Intervention Research
Publisher : National Academies Press
Page : 171 pages
File Size : 42,7 Mb
Release : 2018-01-21
Category : Medical
ISBN : 9780309464871

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Opportunities for Organ Donor Intervention Research by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Issues in Organ Donor Intervention Research Pdf

The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the public's trust in the process of organ donation and transplantation.

Organ Procurement and Transplantation

Institute of Medicine,Committee on Organ Procurement and Transplantation Policy
Organ Procurement and Transplantation Book PDF

Author : Institute of Medicine,Committee on Organ Procurement and Transplantation Policy
Publisher : National Academies Press
Page : 254 pages
File Size : 48,8 Mb
Release : 1999-12-09
Category : Medical
ISBN : 9780309172776

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Organ Procurement and Transplantation by Institute of Medicine,Committee on Organ Procurement and Transplantation Policy Pdf

Each day, nearly 60 Americans receive a transplanted kidney, liver, or other organâ€"a literal "second chance at life"â€"but 11 others die waiting for an organ transplant. The number of donors, although rising, is not growing fast enough to meet the increasing demand. Intended to improve the current system of organ procurement and allocation, the "Final Rule," a 1998 regulation issued by the U.S. Department of Health and Human Services, sparked further controversy with its attempts to eliminate the apparent geographic disparities in the time an individual must wait for an organ. This book assesses the potential impact of the Final Rule on organ transplantation. It also presents new, original analyses of data, and assesses medical practices, social and economic observations, and other information on: access to transplantation services for low-income populations and racial and ethnic minority groups; organ donation rates; waiting times for transplantation; patient survival rates and organ failure rates leading to retransplantation; and cost of organ transplantation services.

Living Kidney Donation

Krista L. Lentine,Beatrice P. Concepcion,Edgar V. Lerma
Living Kidney Donation Book PDF

Author : Krista L. Lentine,Beatrice P. Concepcion,Edgar V. Lerma
Publisher : Springer
Page : 0 pages
File Size : 50,7 Mb
Release : 2022-03-07
Category : Medical
ISBN : 3030536203

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Living Kidney Donation by Krista L. Lentine,Beatrice P. Concepcion,Edgar V. Lerma Pdf

This book provides a complete guide to the evaluation, care, and follow-up of living kidney donors. Living donor kidney transplantation is established as the best treatment option for kidney failure. However, despite the tremendous benefits of living donation to recipients and society, the outcomes and optimal care of donors themselves have received relatively less attention. Fortunately, things are changing – including recent landmark developments in living donor risk assessment, policy and guidance. This volume offers authoritative, evidence-based guidance on the full range of clinical scenarios encountered in the evaluation and care of living kidney donors. The approach to key elements of risk assessment, ethical considerations and informed consent is accompanied by recommendations for patient-centered care before, during, and after donation. Advocacy initiatives and policies to remove disincentives to donation and advance a defensible system of practice are also discussed. General and transplant nephrologists, as well as related allied health professionals, can look to this book as a comprehensive resource addressing contemporary clinical topics in the practice of living kidney donation.

Organ Donation

Institute of Medicine,Board on Health Sciences Policy,Committee on Increasing Rates of Organ Donation
Organ Donation Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Increasing Rates of Organ Donation
Publisher : National Academies Press
Page : 358 pages
File Size : 42,5 Mb
Release : 2006-08-24
Category : Medical
ISBN : 9780309164641

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Organ Donation by Institute of Medicine,Board on Health Sciences Policy,Committee on Increasing Rates of Organ Donation Pdf

Rates of organ donation lag far behind the increasing need. At the start of 2006, more than 90,000 people were waiting to receive a solid organ (kidney, liver, lung, pancreas, heart, or intestine). Organ Donation examines a wide range of proposals to increase organ donation, including policies that presume consent for donation as well as the use of financial incentives such as direct payments, coverage of funeral expenses, and charitable contributions. This book urges federal agencies, nonprofit groups, and others to boost opportunities for people to record their decisions to donate, strengthen efforts to educate the public about the benefits of organ donation, and continue to improve donation systems. Organ Donation also supports initiatives to increase donations from people whose deaths are the result of irreversible cardiac failure. This book emphasizes that all members of society have a stake in an adequate supply of organs for patients in need, because each individual is a potential recipient as well as a potential donor.

Organ Donation and Transplantation

Georgios Tsoulfas
Organ Donation and Transplantation Book PDF

Author : Georgios Tsoulfas
Publisher : BoD – Books on Demand
Page : 454 pages
File Size : 47,9 Mb
Release : 2018-07-25
Category : Medical
ISBN : 9781789233407

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Organ Donation and Transplantation by Georgios Tsoulfas Pdf

One of the most interesting and at the same time most challenging fields of medicine and surgery has been that of organ donation and transplantation. It is a field that has made tremendous strides during the last few decades through the combined input and efforts of scientists from various specialties. What started as a dream of pioneers has become a reality for the thousands of our patients whose lives can now be saved and improved. However, at the same time, the challenges remain significant and so do the expectations. This book will be a collection of chapters describing these same challenges involved including the ethical, legal, and medical issues in organ donation and the technical and immunological problems the experts are facing involved in the care of these patients.The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of organ donation and transplantation.

The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement

Robert S.D. Higgins,Juan A. Sanchez
The Multi Organ Donor A Guide to Selection Preservation and Procurement Book PDF

Author : Robert S.D. Higgins,Juan A. Sanchez
Publisher : Bentham Science Publishers
Page : 216 pages
File Size : 51,7 Mb
Release : 2018-11-30
Category : Medical
ISBN : 9781681087566

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The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement by Robert S.D. Higgins,Juan A. Sanchez Pdf

Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases. The lifesaving potential of transplantation has been limited by the number and quality of appropriate organ donors. The evolution of brain death criteria by the Harvard Ad-Hoc Committee Report has opened the door to understanding the importance of medical, legal and ethical challenges of organ donation in support of the growth of the transplant science. The possibility of organ donation from living donors has enhanced organ availability for patients with kidney failure. Modern inotropes and immunosuppression regimens have been critical to the success of other organ transplant procedures. However, the cornerstone of successful transplantation continues to be the appropriate selection, evaluation, preservation of organ tissues and the successful surgical procurement process to mitigate the impact of tissue ischemia and reperfusion. In this textbook, the art and science of organ donation and tissue preservation is examined. Through this authoritative text by leaders in the field, the editors provide a state of the art review of modern preservation techniques, patient selection and screening criteria, as well as best practices for multi-organ procurement. Information presented in the book will familiarize readers with the initial steps of determining organ availability which ultimately enables health care professionals to realize the extraordinary potential of successful multi-organ transplant procedures. This guide is intended to be a fundamental resource for students, residents, faculty and staff for all disciplines allied to health care delivery and organ donation.

Contemporary Bioethics

Mohammed Ali Al-Bar,Hassan Chamsi-Pasha
Contemporary Bioethics Book PDF

Author : Mohammed Ali Al-Bar,Hassan Chamsi-Pasha
Publisher : Springer
Page : 267 pages
File Size : 44,8 Mb
Release : 2015-05-27
Category : Medical
ISBN : 9783319184289

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Contemporary Bioethics by Mohammed Ali Al-Bar,Hassan Chamsi-Pasha Pdf

This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.

Organ Transplantation in Times of Donor Shortage

Ralf J. Jox,Galia Assadi,Georg Marckmann
Organ Transplantation in Times of Donor Shortage Book PDF

Author : Ralf J. Jox,Galia Assadi,Georg Marckmann
Publisher : Springer
Page : 352 pages
File Size : 40,7 Mb
Release : 2015-08-06
Category : Philosophy
ISBN : 9783319164410

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Organ Transplantation in Times of Donor Shortage by Ralf J. Jox,Galia Assadi,Georg Marckmann Pdf

This book analyzes the reasons for organ shortage and ventures innovative ideas for approaching this problem. It presents 29 contributions from a highly interdisciplinary group of world experts and upcoming professionals in the field. Every year thousands of patients die while waiting for organ transplantation. Health authorities, medical professionals and bioethicists worldwide point to the urgent and yet unsolved problem of organ shortage, which will be even intensified due to the increasing life expectancy. Even though the practical problem seems to be well known, the search for suitable solutions continues and often restricts itself by being limited through disciplinary and national borders. Combining philosophical reflection with empirical results, this volume enables a unique insight in the ethics of organ transplantation and offers fresh ideas for policymakers, health care professionals, academics and the general public.

Strange Harvest

Lesley A. Sharp
Strange Harvest Book PDF

Author : Lesley A. Sharp
Publisher : Univ of California Press
Page : 322 pages
File Size : 53,8 Mb
Release : 2006-10-04
Category : Medical
ISBN : 9780520247864

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Strange Harvest by Lesley A. Sharp Pdf

Illuminates the wondrous yet disquieting medical realm of organ transplantation by drawing on the voices of those most deeply involved: transplant recipients, clinical specialists, and the surviving kin of deceased organ donors. This ethnographic study explores how these parties think about death, loss, and mourning.

Non-Heart-Beating Organ Transplantation

Institute of Medicine,Roger Herdman,John T. Potts
Non Heart Beating Organ Transplantation Book PDF

Author : Institute of Medicine,Roger Herdman,John T. Potts
Publisher : National Academies Press
Page : 103 pages
File Size : 43,5 Mb
Release : 1998-01-18
Category : Medical
ISBN : 9780309064248

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Non-Heart-Beating Organ Transplantation by Institute of Medicine,Roger Herdman,John T. Potts Pdf

Non-heart-beating donors (individuals whose deaths are determined by cessation of heart and respiratory function rather than loss of whole brain function) could potentially be of major importance in reducing the gap between the demand for and available supply of organs for transplantation. Prompted by questions concerning the medical management of such donorsâ€"specifically, whether interventions undertaken to enhance the supply and quality of potentially transplantable organs (i.e. the use of anticoagulants and vasodilators) were in the best interests of the donor patientâ€"the U.S. Department of Health and Human Services asked the Institute of Medicine to examine from scientific and ethical points of view "alternative medical approaches that can be used to maximize the availability of organs from [a] donor [in an end-of-life situation] without violating prevailing ethical norms...." This book examines transplantation supply and demand, historical and modern conceptions of non-heart-beating donors, and organ procurement organizations and transplant program policies, and contains recommendations concerning the principles and ethical issues surrounding the topic.

Regenerative Medicine Applications in Organ Transplantation

Giuseppe Orlando
Regenerative Medicine Applications in Organ Transplantation Book PDF

Author : Giuseppe Orlando
Publisher : Academic Press
Page : 1050 pages
File Size : 55,5 Mb
Release : 2013-10-11
Category : Technology & Engineering
ISBN : 9780123985200

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Regenerative Medicine Applications in Organ Transplantation by Giuseppe Orlando Pdf

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Non-Heart-Beating Organ Transplantation

Institute of Medicine,Division of Health Care Services,Committee on Non-Heart-Beating Transplantation II: The Scientific and Ethical Basis for Practice and Protocols
Non Heart Beating Organ Transplantation Book PDF

Author : Institute of Medicine,Division of Health Care Services,Committee on Non-Heart-Beating Transplantation II: The Scientific and Ethical Basis for Practice and Protocols
Publisher : National Academies Press
Page : 174 pages
File Size : 41,5 Mb
Release : 2000-04-19
Category : Medical
ISBN : 9780309183550

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Non-Heart-Beating Organ Transplantation by Institute of Medicine,Division of Health Care Services,Committee on Non-Heart-Beating Transplantation II: The Scientific and Ethical Basis for Practice and Protocols Pdf

In 1997, the Institute of Medicine published a report entitled Non-Heart- Beating Organ Transplantation: Medical and Ethical Issues in Procurement. The findings and recommendations of that study defined the ethical and scientific basis for non-heart-beating organ donation and transplantation, and provided specific recommendations for practices that affirm patient welfare, promote patient and family choice, and avoid conflicts of interest. Following the 1997 study, the Department of Health and Human Services requested a follow up study to promote such efforts. The central activity for this study was a workshop held in Washington, D.C., on May 24-25, 1999. The workshop provided the opportunity for extensive dialogue on non-heart-beating organ donation among hospitals and organ procurement organizations (OPOs) that are actively involved in non-heartbeating organ and tissue donation and those with concerns about whether and how to proceed. The findings and recommendations of this report are based in large measure on the discussions and insights from that workshop. Non-Heart-Beating Organ Transplantation includes seven recommendations for developing and implementing non-heart-beating-donor protocols. These recommendations were based on the findings and recommendations from the 1997 IOM report and consensus achieved among participants at the national workshop. The committee developed these recommendations as steps towards an approach to non-heart-beating-donor organ donation and procurement consistent with underlying scientific and ethical guidelines, patient and family options and choices, and public trust in organ donation.

Organ Transplants

Tina P. Schwartz
Organ Transplants Book PDF

Author : Tina P. Schwartz
Publisher : Rowman & Littlefield
Page : 256 pages
File Size : 52,5 Mb
Release : 2005
Category : Transplantation of organs, tissues, etc
ISBN : 9780810849242

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Organ Transplants by Tina P. Schwartz Pdf

Talks to teens and offers practical advice and suggestions for coping with and surviving the situation of when a family member has an organ transplant, or when they are personally facing an organ transplant. It covers how to deal with events that happen before, during, and after the surgery.

The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement

Juan A. Sanchez,Robert S. D. Higgins
The Multi Organ Donor A Guide to Selection Preservation and Procurement Book PDF

Author : Juan A. Sanchez,Robert S. D. Higgins
Publisher : Current and Future Development
Page : 216 pages
File Size : 46,6 Mb
Release : 2018-11-30
Category : Medical
ISBN : 168108757X

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The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement by Juan A. Sanchez,Robert S. D. Higgins Pdf

Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases. The lifesaving potential of transplantation has been limited by the number and quality of appropriate organ donors. The evolution of brain death criteria by the Harvard Ad-Hoc Committee Report has opened the door to understanding the importance of medical, legal and ethical challenges of organ donation in support of the growth of the transplant science. The possibility of organ donation from living donors has enhanced organ availability for patients with kidney failure. Modern inotropes and immunosuppression regimens have been critical to the success of other organ transplant procedures. However, the cornerstone of successful transplantation continues to be the appropriate selection, evaluation, preservation of organ tissues and the successful surgical procurement process to mitigate the impact of tissue ischemia and reperfusion. In this textbook, the art and science of organ donation and tissue preservation is examined. Through this authoritative text by leaders in the field, the editors provide a state of the art review of modern preservation techniques, patient selection and screening criteria, as well as best practices for multi-organ procurement. Information presented in the book will familiarize readers with the initial steps of determining organ availability which ultimately enables health care professionals to realize the extraordinary potential of successful multi-organ transplant procedures. This guide is intended to be a fundamental resource for students, residents, faculty and staff for all disciplines allied to health care delivery and organ donation.

Organ Transplantation

Andrew A. Klein,Clive J. Lewis,Joren C. Madsen
Organ Transplantation Book PDF

Author : Andrew A. Klein,Clive J. Lewis,Joren C. Madsen
Publisher : Cambridge University Press
Page : 391 pages
File Size : 41,7 Mb
Release : 2011-08-11
Category : Medical
ISBN : 9781139498241

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Organ Transplantation by Andrew A. Klein,Clive J. Lewis,Joren C. Madsen Pdf

Organ Transplantation: A Clinical Guide covers all aspects of transplantation in both adult and pediatric patients. Cardiac, lung, liver, kidney, pancreas and small bowel transplantation are discussed in detail, as well as emerging areas such as face and pancreatic islet cell transplantation. For each organ, chapters cover basic science of transplantation, recipient selection, the transplant procedure, anesthetic and post-operative care, and long-term follow-up and management of complications. Important issues in donor selection and management are also discussed, including recruitment and allocation of potential donor organs and expanding the donor pool. Summary tables and illustrations enhance the text, and long-term outcome data are provided where available. Written by expert transplant surgeons, anesthetists and physicians, Organ Transplantation: A Clinical Guide is an invaluable multidisciplinary resource for any clinician involved in transplantation, providing in-depth knowledge of specialist areas of transplantation and covering the full range of management strategies.