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Author : Henricus A. M. (Rick) Mutsaers,Rikke Norregaard,Peter Olinga
Publisher : Frontiers Media SA
Page : 144 pages
File Size : 50,9 Mb
Release : 2022-01-05
Category : Medical
ISBN : 9782889719495
Author : Wei Zhao,Zhe-Sheng Chen,Haishi Qiao
Publisher : Frontiers Media SA
Page : 136 pages
File Size : 51,6 Mb
Release : 2022-05-10
Category : Science
ISBN : 9782889761678
Author : Tingting Zhao,Qin Zhou
Publisher : Frontiers Media SA
Page : 124 pages
File Size : 48,7 Mb
Release : 2022-04-08
Category : Medical
ISBN : 9782889748860
Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 49,9 Mb
Release : 1994
Category : Electronic
ISBN : OCLC:78842116
Author : Victor R. Preedy,Vinood B. Patel
Publisher : Springer
Page : 0 pages
File Size : 49,5 Mb
Release : 2017-07-14
Category : Medical
ISBN : 9400776748
In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.
Author : Yuxia Zhao,Panpan Hao,Peizhe Wang,Fujian Lu,Yanping Liu
Publisher : Frontiers Media SA
Page : 275 pages
File Size : 44,9 Mb
Release : 2023-06-01
Category : Science
ISBN : 9782832525593
Author : Timothy B. Niewold
Publisher : Frontiers Media SA
Page : 88 pages
File Size : 40,5 Mb
Release : 2015-04-21
Category : Immunologic diseases. Allergy
ISBN : 9782889193400
The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease. Type I interferons function as a bridge between the innate and adaptive immune systems, and as such play an important role in setting thresholds for response against self antigens. Many investigators have focused on the role type I interferons play in autoimmune disease. This fascinating and rapidly growing body of literature encompasses many different autoimmune diseases, including systemic lupus erythematosus, type I diabetes, multiple sclerosis, and others. In this Research Topic, we provide a comprehensive overview of the various roles type I interferons play in autoimmune diseases, with a focus on human immunology.
Author : Xiaolin Sun,Yudong Liu,Jing He,Jill M. Kramer,Miao Pan
Publisher : Frontiers Media SA
Page : 117 pages
File Size : 46,8 Mb
Release : 2023-09-29
Category : Medical
ISBN : 9782832534595
Author : Rudolf Ludwig Karl Virchow
Publisher : Legare Street Press
Page : 0 pages
File Size : 47,7 Mb
Release : 2022-10-27
Category : Health & Fitness
ISBN : 1015708765
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author : John Varga,Christopher P. Denton,Fredrick M. Wigley,Yannick Allanore,Masataka Kuwana
Publisher : Springer
Page : 743 pages
File Size : 41,5 Mb
Release : 2016-11-07
Category : Medical
ISBN : 9783319314075
Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.
Author : Pablo Muriel
Publisher : Academic Press
Page : 914 pages
File Size : 46,6 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9780128043219
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Author : Hao Wang,Caigan Du
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 49,6 Mb
Release : 2022-03-09
Category : Science
ISBN : 9782889744084
Publisher’s note: This is a 2nd edition due to an article retraction.
Author : Chandrashekhar Gandhi,Massimo Pinzani
Publisher : Academic Press
Page : 335 pages
File Size : 46,6 Mb
Release : 2015-04-10
Category : Science
ISBN : 9780128005446
Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.
Author : Elvira Forte,Isotta Chimenti,Gonzalo del Monte-Nieto,Susanne Sattler
Publisher : Frontiers Media SA
Page : 369 pages
File Size : 49,7 Mb
Release : 2022-02-23
Category : Science
ISBN : 9782889744978
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 48,5 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875
As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase