Organic Synthesis Via Examination Of Selected Natural Products

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Organic Synthesis Via Examination of Selected Natural Products

Author : David J. Hart
Publisher : World Scientific
Page : 589 pages
File Size : 55,7 Mb
Release : 2011
Category : Science
ISBN : 9789814313704

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Organic Synthesis Via Examination of Selected Natural Products by David J. Hart Pdf

Complete with problems and solutions, this book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but includes some unnatural products synthesis. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products. The book includes power-point presentations to provide teachers who do not (or do) specialize in organic synthesis with access to well-organized material they can use in the classroom (with advanced students). The book provides the reader with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided. This is much more helpful to the reader than the usual author-journal-year-page information.

Total Synthesis of Natural Products

Author : Jie Jack Li,E.J. Corey
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 47,8 Mb
Release : 2013-03-14
Category : Science
ISBN : 9783642340659

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Total Synthesis of Natural Products by Jie Jack Li,E.J. Corey Pdf

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Chemistry of Natural Products

Author : Sujata V. Bhat,B.A. Nagasampagi,Meenakshi Sivakumar
Publisher : Springer Science & Business Media
Page : 886 pages
File Size : 40,6 Mb
Release : 2005-01-04
Category : Science
ISBN : 3540406697

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Chemistry of Natural Products by Sujata V. Bhat,B.A. Nagasampagi,Meenakshi Sivakumar Pdf

During the last few decades, research into natural products has advanced tremendously thanks to contributions from the fields of chemistry, life sciences, food science and material sciences. Comparisons of natural products from microorganisms, lower eukaryotes, animals, higher plants and marine organisms are now well documented. This book provides an easy-to-read overview of natural products. It includes twelve chapters covering most of the aspects of natural products chemistry. Each chapter covers general introduction, nomenclature, occurrence, isolation, detection, structure elucidation both by degradation and spectroscopic techniques, biosynthesis, synthesis, biological activity and commercial applications, if any, of the compounds mentioned in each topic. Therefore it will be useful for students, other researchers and industry. The introduction to each chapter is brief and attempts only to supply general knowledge in the particular field. Furthermore, at the end of each chapter there is a list of recommended books for additional study and a list of relevant questions for practice.

Biosynthesis of Natural Products

Author : Paolo Manitto
Publisher : Unknown
Page : 560 pages
File Size : 40,9 Mb
Release : 1981
Category : Biosynthesis
ISBN : UCSD:31822010373181

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Biosynthesis of Natural Products by Paolo Manitto Pdf

Efficiency in Natural Product Total Synthesis

Author : Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 47,5 Mb
Release : 2018-07-20
Category : Science
ISBN : 9781118940204

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Efficiency in Natural Product Total Synthesis by Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung Pdf

Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

The Way of Synthesis

Author : Tomas Hudlicky,Josephine W. Reed
Publisher : Wiley-VCH
Page : 1032 pages
File Size : 50,7 Mb
Release : 2007-09-04
Category : Science
ISBN : UVA:X030338033

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The Way of Synthesis by Tomas Hudlicky,Josephine W. Reed Pdf

This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)

Chemistry of Natural Products

Author : K. Anand Solomon
Publisher : MJP Publisher
Page : 184 pages
File Size : 48,8 Mb
Release : 2019-06-11
Category : Science
ISBN : 8210379456XXX

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Chemistry of Natural Products by K. Anand Solomon Pdf

Natural products, i.e., products from Nature, be it of plant or animal origin, plays a major role in human life. Hence their isolation and characterization of natural products will help in understanding their mode of action with reference to their biological and pharmacological activity. The book has been written with a view that it would help both students and researchers who are in their initial stages of exploration in the field of Natural product chemistry.The importance of natural products, techniques for the analysis,interpretation of the data and finally its role in health care has been dealt with. With the voluminous information available on each such topic, only the basic aspect, hopefully to elicit interest in further exploration has been discussed.

Natural Products

Author : Sujata V. Bhat,Bhimsen A. Nagasampagi,Meenakshi Sivakumar
Publisher : Alpha Science International, Limited
Page : 0 pages
File Size : 46,7 Mb
Release : 2009
Category : Science
ISBN : 1842654055

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Natural Products by Sujata V. Bhat,Bhimsen A. Nagasampagi,Meenakshi Sivakumar Pdf

The major aim of this book is to provide an easy to read overview of chemistry and applications of natural products. It includes fourteen chapters covering most of the aspects of natural products chemistry. The result of the authors' present endeavors is the unique monograph that presents comprehensive information on occurrence, chemistry, biosynthesis and applications of various natural products. First twelve chapters cover general introduction, nomenclature, occurrence, isolation, detection, structure elucidation by degradation, biosynthesis, synthesis, biological activity and commercial applications, if any, of the compounds mentioned in each topic. Some fascinating syntheses of natural products and applications of enzymes in organic synthesis are discussed in chapters 13 and 14 respectively. In addition, there is general introduction for natural products. Therefore the present textbook will be useful for students, other researchers and industry.

The Total Synthesis of Natural Products

Author : John ApSimon
Publisher : Wiley-Interscience
Page : 610 pages
File Size : 49,5 Mb
Release : 1981-05-12
Category : Science
ISBN : 0471054607

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The Total Synthesis of Natural Products by John ApSimon Pdf

The Vocabulary of Organic Chemistry Milton Orchin, Fred Kaplan,Roger S. Macomber, R. Marshall Wilson & Hans W. ZimmerIdentifies those terms and concepts which now constitute thevocabulary of organic chemists, then defines and explains theseterms and concepts, most often using examples. Organized so thatsubject matter builds successively on increasingly varied andcomplex material. All terms and concepts related to a particulararea are placed together, except for one chapter on name and typereactions, which is alphabetically arranged. The only book of itskind--valuable to students, teachers and chemical professionalsalike. 1980 Protective Groups in Organic Synthesis Theodora W.Greene Provides essential information on transformations of organicmolecules, including instructions and references for the protectionand regeneration of the major organic functional groups: -OH, -NH,-SH, -COOH, and C = O. Covers the best methods of formation andcleavage, properties of protective groups, selection of a group fora particular need. Organization is by functional groups to beprotected, with groups arranged in order of increasing complexityof structure, and with most efficient methods of formation orcleavage described first. Charts show the reactivities of 270 ofthe most commonly used protective groups to 108 reagents, selectedas prototypes for the entire array of reagents available to theorganic chemist. 1981 Basics of Electroorganic Synthesis DemetriosK. Kyriacou A veteran organic electrochemist illuminatesfundamental ideas and principles by means of selected examples fromthe literature and his own research, demonstrating the practicalunity of the field in a clear, concise manner. Describes thegeneral electroorganic reaction and illustrates the general mode ofconcepts and applications in the area of electrosynthesis. Containsa brief survey of electroorganic reactions and coverage of specialtopics and the praxis of electroorganic synthesis. 1981

Natural Products

Author : J. Mann
Publisher : Longman Publishing Group
Page : 502 pages
File Size : 55,6 Mb
Release : 1994
Category : Biochemistry
ISBN : UCSD:31822020600318

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Natural Products by J. Mann Pdf

An account of the structure, chemistry, biosynthesis, and biological activity of most types of organic compounds, with each chapter devoted to classes of compounds, such as carbohydrates, nucleotides and polynucleotides, fatty acids, terpenoids, phenolics, and alkaloids. Includes numerous bandw diagrams. An excellent complement to a standard text on basic organic chemistry. For senior undergraduates and graduate students of organic and medicinal chemistry, biochemistry, pharmacy, and pharmacology. Annotation copyright by Book News, Inc., Portland, OR

Asymmetric Synthesis of Natural Products

Author : Ari Koskinen
Publisher : John Wiley & Sons
Page : 252 pages
File Size : 45,5 Mb
Release : 1993
Category : Science
ISBN : UOM:49015002054493

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Asymmetric Synthesis of Natural Products by Ari Koskinen Pdf

Introducing students to the rapidly growing field of the asymmetric synthesis of natural products in organic chemistry, this textbook clearly rationalizes the reasons for the major symmetric transformations. A number of chapters cover individual classes of natural products: their structure, biosynthesis and interrelationship; as well as providing examples of symmetric syntheses and the practical value of these compounds.

The Total Synthesis of Natural Products

Author : John ApSimon
Publisher : Wiley-Interscience
Page : 720 pages
File Size : 49,8 Mb
Release : 2009-09-22
Category : Science
ISBN : 9780470129593

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The Total Synthesis of Natural Products by John ApSimon Pdf

The Total Synthesis of Natural Products Volume Seven Edited by John ApSimon This volume contains a chapter updating monoterpene synthesis and reviews the newer areas of leukotrienes and macrocyclic lactones. 1988 (0 471-88076-0) 480 pp. The Total Synthesis of Natural Products Volume Six Edited by John ApSimon Volume Six considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments, and genes. 1984 (0 471-09900-7) 304 pp. The Total Synthesis of Natural Products Volume Five Edited by John ApSimon This present volume considers the total syntheses of sesquiterpenes, reflecting, in part, the heightened research activity in this area. 1983 (0 471-09808-6) 560 pp. The Total Synthesis of Natural Products Volume Four Edited by John ApSimon The fourth volume in this successful series offers synthetic approaches to a wide variety of natural products, including the synthesis of cannabinoids, natural inophores, insect pheromones, monoterpenes, and prostaglandins. 1981 (0 471-05460-7) 624 pp. The Total Synthesis of Natural Products Volume Three Edited by John ApSimon 1977 (0 471-02392-2) 576 pp. The Total Synthesis of Natural Products Volume Two Edited by John ApSimon 1973 (0 471-03252-2) 768 pp. The Total Synthesis of Natural Products Volume One Edited by John ApSimon 1973 (0 471-03251-4) 624 pp.

Biomimetic Organic Synthesis, 2 Volume Set

Author : Erwan Poupon,Bastien Nay
Publisher : Wiley-VCH
Page : 0 pages
File Size : 45,7 Mb
Release : 2011-06-07
Category : Science
ISBN : 3527325808

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Biomimetic Organic Synthesis, 2 Volume Set by Erwan Poupon,Bastien Nay Pdf

In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature. Volume 1 describes the biomimetic synthesis of alkaloids. Volume 2 covers terpenes, polyketides, and polyphenols. A discussion of the current challenges and frontiers in biomimetic synthesis concludes this comprehensive handbook. Key features: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming, making this comprehensive 2 volume work a must-have for everyone working in the field. Unifying both synthetic and biosynthetic aspects, this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry.