Total Synthesis Of Natural Products

Author : Jie Jack Li,E.J. Corey
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 42,7 Mb
Release : 2013-03-14
Category : Science
ISBN : 9783642340659

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Total Synthesis of Natural Products by Jie Jack Li,E.J. Corey Pdf

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Author : Jie Jack Li,E.J. Corey
Publisher : Springer
Page : 0 pages
File Size : 51,6 Mb
Release : 2015-04-12
Category : Science
ISBN : 3642440924

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Total Synthesis of Natural Products by Jie Jack Li,E.J. Corey Pdf

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Author : Jie Jack Li,E.J. Corey
Publisher : Springer
Page : 0 pages
File Size : 43,6 Mb
Release : 2013-03-19
Category : Science
ISBN : 3642340644

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Total Synthesis of Natural Products by Jie Jack Li,E.J. Corey Pdf

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 350 pages
File Size : 54,7 Mb
Release : 2019-04-27
Category : Science
ISBN : 9780081028230

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Total Synthesis of Bioactive Natural Products by Goutam Brahmachari Pdf

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products. Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules Outlines each step of the process in detail, with full experimental information supported by extensive schemes Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule

Author : Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 44,7 Mb
Release : 2018-07-24
Category : Science
ISBN : 9781118940211

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Efficiency in Natural Product Total Synthesis by Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung Pdf

Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Author : Stephen Hanessian
Publisher : Unknown
Page : 291 pages
File Size : 53,9 Mb
Release : 1986
Category : Electronic
ISBN : OCLC:778160253

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Total Synthesis of Natural Products by Stephen Hanessian Pdf

Author : Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 41,5 Mb
Release : 2018-10-16
Category : Science
ISBN : 9781118605400

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Efficiency in Natural Product Total Synthesis by Pei-Qiang Huang,Zhu-Jun Yao,Richard P. Hsung Pdf

Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Author : John ApSimon
Publisher : John Wiley & Sons
Page : 483 pages
File Size : 55,5 Mb
Release : 2009-09-22
Category : Science
ISBN : 9780470129586

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The Total Synthesis of Natural Products, Volume 7 by John ApSimon Pdf

The appearance of the seventh volume of The Total Synthesis of Natural Products signals the continued health of the art and science of organic synthesis. This new volume contains a chapter updating monoterpene synthesis and reviews the newer areas of leukotrienes and macro-cyclic lactones. The Total Synthesis of Natural Products, Volume Seven forms an integral part of the invaluable working reference begun in Volumes One through Six, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.

Author : John ApSimon
Publisher : Unknown
Page : 0 pages
File Size : 51,8 Mb
Release : 1973
Category : Organic compounds
ISBN : LCCN:72004075

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The Total Synthesis of Natural Products by John ApSimon Pdf

Author : Sasadhar Majhi,Bhubaneswar Mandal
Publisher : World Scientific
Page : 469 pages
File Size : 48,7 Mb
Release : 2023-04-25
Category : Science
ISBN : 9789811268700

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Modern Sustainable Techniques In Total Synthesis Of Bioactive Natural Products by Sasadhar Majhi,Bhubaneswar Mandal Pdf

Modern Sustainable Techniques in Total Synthesis of Bioactive Natural Products comprises five parts for green tools, such as ultrasonic waves, microwave heating, visible-light photochemistry, organic electrochemistry, and flow chemistry, along with 72 chapters for each bioactive molecule of natural origin. Each chapter explores the natural source, structure, systematic name, structural features, compound class, biological activity, conventional approaches for their chemical synthesis, and demerit(s) of conventional approaches (where applicable). Finally, critical features of total synthesis using modern sustainable techniques, including reaction types, synthetic strategy, and synthetic route utilizing modern sustainable tools for each bioactive natural product and secondary metabolites, are discussed brilliantly. The spectrum of application of total synthesis of bioactive natural products using modern sustainable techniques may promote the development of more eco-friendly synthetic processes so that the next generations can live on this planet with a minimum energy requirement for chemical reactions with the least pollution.

Author : John ApSimon,David Jonathan Goldsmith
Publisher : Wiley-Interscience
Page : 774 pages
File Size : 40,8 Mb
Release : 1973-10-26
Category : Science
ISBN : UOM:39015016062815

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The Total Synthesis of Natural Products, Volume 2 by John ApSimon,David Jonathan Goldsmith Pdf

Each volume reviews the total synthesis of a set of compounds looking at syntheses reported historically and at the practice current at the time of publication. From volume 1 focusing on carbohydrates, prostagladins, nucleic acids, antibiotics, naturally occurring oxygen ring compounds and pyrrole pigments, the series continues with coverage of aromatic steroids, monoterpenes, triterpenes, sesquiterpenes, cannabinoids, natural inophores, insect pheromones and alkaloids. Volumes revisit the total synthesis of key compounds such as carbohydrates, nucleic acids and pyrrole pigments several times during the series building a picture of the historic development of total synthesis techniques for these major groups. Chapters are edited by experts in their field to give a complete overview of the best in the field at the time.

Author : Alexandros L. Zografos
Publisher : John Wiley & Sons
Page : 585 pages
File Size : 43,9 Mb
Release : 2016-04-18
Category : Science
ISBN : 9781118751732

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From Biosynthesis to Total Synthesis by Alexandros L. Zografos Pdf

Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field

Author : Stephen Hanessian
Publisher : Pergamon
Page : 324 pages
File Size : 49,6 Mb
Release : 1983
Category : Science
ISBN : UOM:39015015993028

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Total Synthesis of Natural Products, the "Chiron" Approach by Stephen Hanessian Pdf

Author : Olivier Piva
Publisher : John Wiley & Sons
Page : 314 pages
File Size : 42,6 Mb
Release : 2019-12-12
Category : Science
ISBN : 9781786303493

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Retrosynthetic Analysis and Synthesis of Natural Products 1 by Olivier Piva Pdf

For chemists, attempting to mimic nature by synthesizing complex natural products from raw material is a challenge that is fraught with pitfalls. To tackle this unique but potentially rewarding task, researchers can rely on well-established reactions and methods of practice, or apply their own synthesis methods to verify their potential. Whatever the goal and its complexity, there are multiple ways of achieving it. We must now establish a strategic and effective plan that requires the minimum number of steps, but lends itself to widespread use. This book is structured around the study of a dozen target products (butyrolactone, macrolide, indole compound, cyclobutanic terpene, spiro- and polycyclic derivatives, etc.). For each product, the different disconnections are presented and the associated syntheses are analyzed step by step. The key reactions are described explicitly, followed by diagrams showing the range of impact of certain transformations. This set of data alone is conducive to understanding syntheses and indulging in this difficult, but worthwhile activity.

Author : Goutam Brahmachari
Publisher : World Scientific
Page : 695 pages
File Size : 45,7 Mb
Release : 2012
Category : Science
ISBN : 9789814335379

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Bioactive Natural Products by Goutam Brahmachari Pdf

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.