Organoselenium Chemistry Between Synthesis And Biochemistry

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Organoselenium Chemistry Between Synthesis and Biochemistry

Author : Claudio Santi
Publisher : Bentham Science Publishers
Page : 442 pages
File Size : 53,7 Mb
Release : 2014-04-30
Category : Science
ISBN : 9781608058389

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Organoselenium Chemistry Between Synthesis and Biochemistry by Claudio Santi Pdf

The use of organoselenium reagents as catalysts is a common thread that runs through the chapters of this book, introducing important aspects of the modern organoselenium chemistry: organocatalysis, green chemistry, bioinspiration, antioxidant activity. The eBook covers the most recent developments in the classical synthetic application of organoselenium reagents such as electrophilic, nucleophilic and free radical reagents. The volume also features a discussion on the synthesis and the synthetic applications of some emerging classes of selenium compounds such as hypervalent selenium species and selenoamides, and also addresses some biological aspects such as the antimicrobial activity of organoselenium derivatives and the biochemistry of selenoproteins. A number of eminent scientists from different research groups were involved in the preparation of the 13 chapters of the book, making Organoselenium Chemistry: Between Synthesis and Biochemistry an excellent reference about selenium chemistry for researchers and graduate students in the field of selenium chemistry.

Organoselenium Compounds in Biology and Medicine

Author : Vimal Kumar Jain,K Indira Priyadarsini
Publisher : Royal Society of Chemistry
Page : 476 pages
File Size : 55,7 Mb
Release : 2017-09-26
Category : Science
ISBN : 9781788012232

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Organoselenium Compounds in Biology and Medicine by Vimal Kumar Jain,K Indira Priyadarsini Pdf

Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

Organoselenium Chemistry

Author : Brindaban C. Ranu,Bubun Banerjee
Publisher : Walter de Gruyter GmbH & Co KG
Page : 436 pages
File Size : 41,5 Mb
Release : 2020-04-20
Category : Science
ISBN : 9783110625110

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Organoselenium Chemistry by Brindaban C. Ranu,Bubun Banerjee Pdf

Organoselenium Chemistry is a unique resource in this branch of organic/organometallic chemistry. The authors give an overview of synthesis strategies, introduce bioactive and environmentally friendly organoselenium compounds and discuss their applications from organic synthesis to the clinic.

New Frontiers in Organoselenium Compounds

Author : Eder João Lenardão,Claudio Santi,Luca Sancineto
Publisher : Springer
Page : 189 pages
File Size : 52,7 Mb
Release : 2018-06-29
Category : Science
ISBN : 9783319924052

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New Frontiers in Organoselenium Compounds by Eder João Lenardão,Claudio Santi,Luca Sancineto Pdf

This book presents recent advances in and perspectives on the use of organoselenium compounds, primarily highlighting the new frontiers in the field of Green Chemistry, their therapeutic and biological relevance and new materials. Throughout its 200 pages, readers will find an updated and comprehensive review of new aspects of organoselenium chemistry and biochemistry. Fully referenced and written in an easy to read style, it offers readers a primary resource for including organoselenium derivatives in their projects. This book will be of interest to specialists, students and researchers involved in a broad range of fields, from synthetic green chemistry to medicinal chemistry and the chemistry of natural products. The connection between organoselenium compounds and green chemistry, despite having only recently emerged, is one of the subjects of this book. The first chapter highlights the use of Se-containing molecules as reagents and catalysts in new green protocols to access important organic transformations. The book provides a wealth of examples of bioactive Se-containing molecules, especially focusing on those with potential therapeutic uses. The second chapter focuses on the state of the art concerning the role of organoselenium compounds as antioxidants, GPx mimics, and derivatives endowed with different bioactive properties. “Organoselenium in nature” is the title of the third chapter, which equips readers with essential information on the main natural organoselenium compounds and where they are found. Selected aspects of the metabolism of selenium in plants and microorganisms are also discussed. In closing, the book includes a chapter dedicated to recent advances concerning the nonbonding interactions between organochalcogen compounds. This is currently a hot topic in selenium chemistry and biochemistry, and here readers will find key insights into the chalcogen bond and its role in the biological activity of organoselenium compounds.

Organoselenium Chemistry

Author : Thomas Wirth
Publisher : John Wiley & Sons
Page : 441 pages
File Size : 51,5 Mb
Release : 2012-01-09
Category : Science
ISBN : 9783527641956

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Organoselenium Chemistry by Thomas Wirth Pdf

Selenium-based methods in synthetic chemistry have developed rapidly over the past years and are now offering highly useful tools for organic synthesis. Filling the gap for a comprehensive handbook and ready reference, this book covers all modern developments within the field, including biochemical aspects. The chemistry chapters are organized according to the different reactivities of various selenium compounds and reagents, with each chapter dealing with a special reaction type. Also includes a table with 77Se NMR shifts to aid in practical problems. From the Contents: * Electrophilic and Nucleophilic Selenium * Selenium Compounds in Radical Reactions * Selenium-Stabilized Carbanions * Selenium Compounds with Valency Higher than Two * Selenocarbonyls * Selenoxide Elimination and [2,3]-Sigmatropic Rearrangement * Selenium Compounds as Ligands and Catalysts * Biological and Biochemical Aspects of Selenium Compounds

Organoselenium Chemistry

Author : Thomas Wirth
Publisher : Springer
Page : 259 pages
File Size : 43,9 Mb
Release : 2003-07-01
Category : Science
ISBN : 9783540481713

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Organoselenium Chemistry by Thomas Wirth Pdf

Embarking on a new millennium, the book in hands describes the recent developments of organsoselenium chemistry in all facets. Various distinguished scientists have contributed, with their skill and expertise, making this book a valuable source for synthetic oriented organic chemists and for those, who want to get a first insight into the chemistry of selenium.

Organoselenium Chemistry

Author : Thomas Wirth
Publisher : Springer
Page : 259 pages
File Size : 55,5 Mb
Release : 2014-03-12
Category : Science
ISBN : 366215658X

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Organoselenium Chemistry by Thomas Wirth Pdf

Embarking on a new millennium, the book in hands describes the recent developments of organsoselenium chemistry in all facets. Various distinguished scientists have contributed, with their skill and expertise, making this book a valuable source for synthetic oriented organic chemists and for those, who want to get a first insight into the chemistry of selenium.

Organoselenium Chemistry

Author : Brindaban C. Ranu,Bubun Banerjee
Publisher : Walter de Gruyter GmbH & Co KG
Page : 574 pages
File Size : 44,8 Mb
Release : 2020-04-20
Category : Science
ISBN : 9783110622294

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Organoselenium Chemistry by Brindaban C. Ranu,Bubun Banerjee Pdf

Organoselenium Chemistry is a unique resource in this branch of organic/organometallic chemistry. The authors give an overview of synthesis strategies, introduce bioactive and environmentally friendly organoselenium compounds and discuss their applications from organic synthesis to the clinic.

Organoselenium Chemistry I

Author : Alain Krief,Laszlo Hevesi
Publisher : Springer Science & Business Media
Page : 232 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642732416

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Organoselenium Chemistry I by Alain Krief,Laszlo Hevesi Pdf

During the last fifteen years organoselenium chemistry underwent a spectacular mutation: from an exotic area of science practised by a few specialists it became a relatively well mastered and widely used methodology of synthetic organic chemistry. The key to this success is that a fair number of selenium based reagents and reactions have been discovered, which are able to perform specific transformations selectively and often under very mild conditions. The aim of this volume is to present the different selenium containing reagents now available to chemists, to mention the scope as well as the limitations of their reactions, and to compare those which possess similar reactivities. The authors present the reagents in the order of increasing oxidation level around the selenium atom.

Organoselenium Chemistry

Author : Thomas G. Back
Publisher : OUP Oxford
Page : 313 pages
File Size : 42,9 Mb
Release : 1999-07-22
Category : Science
ISBN : 9780191589195

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Organoselenium Chemistry by Thomas G. Back Pdf

Organoselenium chemistry is proving increasingly valuable to the synthetic organic chemist. Selenium residues are easily introduced into organic molecules, they serve to effect a variety of useful transformations, and are easily removed at the end of the sequence. These processes are often characterized by high chemo- regio- and stereoselectivity. Recent enantioselective variations of selenium-mediated reactions are further extending their scope and utility. The use of organoselenium compounds in organic conductors is another area of intense current interest. Organoselenium Chemistry - A Practical Approach is written by an international group of experts in the field.

Selenium and Tellurium Reagents

Author : Risto Laitinen,Raija Oilunkaniemi
Publisher : Walter de Gruyter GmbH & Co KG
Page : 466 pages
File Size : 54,7 Mb
Release : 2019-04-01
Category : Science
ISBN : 9783110529340

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Selenium and Tellurium Reagents by Risto Laitinen,Raija Oilunkaniemi Pdf

Selenium and Tellurium Reagents provides an in-depth overview of recent advances on the chemistry of these elements. Written by internationally recognized experts, it gives insight into the synthesis, structure, analysis and mechanistic studies of these compounds. The book is organized into four parts which reflect the applications of Se and Te reagents in four areas: inorganic chemistry, organic chemistry, materials science and biochemistry.

Selenium and Tellurium Reagents

Author : Risto Laitinen,Raija Oilunkaniemi
Publisher : Walter de Gruyter GmbH & Co KG
Page : 668 pages
File Size : 49,8 Mb
Release : 2019-04-01
Category : Science
ISBN : 9783110528107

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Selenium and Tellurium Reagents by Risto Laitinen,Raija Oilunkaniemi Pdf

Selenium and Tellurium Reagents provides an in-depth overview of recent advances on the chemistry of these elements. Written by internationally recognized experts, it gives insight into the synthesis, structure, analysis and mechanistic studies of these compounds. The book is organized into four parts which reflect the applications of Se and Te reagents in four areas: inorganic chemistry, organic chemistry, materials science and biochemistry.

Organochalcogen Compounds

Author : Eder João Lenardão,Claudio Santi,Gelson Perin,Diego Alves
Publisher : Elsevier
Page : 341 pages
File Size : 49,7 Mb
Release : 2022-05-17
Category : Science
ISBN : 9780128194508

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Organochalcogen Compounds by Eder João Lenardão,Claudio Santi,Gelson Perin,Diego Alves Pdf

Organochalcogen compounds reviews the state of the art in new green protocols involving organochalcogen compounds (Se, S, and Te), including the use of nonconventional reaction media, alternative solvents, and solvent-free protocols to prepare these important compounds. Bringing together several leading researchers in organochalcogen chemistry, it provides an authoritative overview of the current state of the field and compiles recent advances in methodologies for the application of green chemistry principles in compound development. These include the use of organochalcogen compounds as intermediates, catalysts, or target products across a range of applications. The recent developments outlined in in the book reflect the efforts of the researchers in this area to move toward a more sustainable chemistry, giving the book the dual benefit of highlighting the latest developments in the field while also showing how the principles of green chemistry can effectively be included in active research projects. Thus it is a valuable reference for chemists, particularly those working in organic, green, and synthetic chemistry across both academia and industry. Highlights green synthetic methods with potential application in the synthesis of natural compounds or other biologically active scaffolds Explores the chemical modification of natural compounds by insertion of organochalcogen groups for the preparation of boosted bioactive semisynthetic molecules Discuss how redox catalysis and catalysis in flow conditions using eco-friendly oxidant can provide new opportunities for the synthesis of linear ad cyclic derivatives

Chiral Building Blocks in Asymmetric Synthesis

Author : Elzbieta Wojaczynska,Jacek Wojaczynski
Publisher : John Wiley & Sons
Page : 692 pages
File Size : 51,6 Mb
Release : 2022-08-08
Category : Science
ISBN : 9783527349463

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Chiral Building Blocks in Asymmetric Synthesis by Elzbieta Wojaczynska,Jacek Wojaczynski Pdf

Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.

Organoselenium Chemistry

Author : Thomas Wirth
Publisher : Springer
Page : 0 pages
File Size : 44,7 Mb
Release : 2000-02-25
Category : Science
ISBN : 3540665161

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Organoselenium Chemistry by Thomas Wirth Pdf

Embarking on a new millennium, the book in hands describes the recent developments of organsoselenium chemistry in all facets. Various distinguished scientists have contributed, with their skill and expertise, making this book a valuable source for synthetic oriented organic chemists and for those, who want to get a first insight into the chemistry of selenium.