Oxygen Biology And Hypoxia

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 42,8 Mb
Release : 2007
Category : Electronic
ISBN : OCLC:760723829

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Oxygen Biology and Hypoxia by Anonim Pdf

Author : Anonim
Publisher : Elsevier
Page : 867 pages
File Size : 49,8 Mb
Release : 2004-05-10
Category : Science
ISBN : 9780080497198

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Oxygen Sensing by Anonim Pdf

The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

Author : Kusal Das,Mallanagouda Shivanagouda Biradar
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 40,8 Mb
Release : 2018-12-12
Category : Medical
ISBN : 9781789848281

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Hypoxia and Anoxia by Kusal Das,Mallanagouda Shivanagouda Biradar Pdf

The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.

Author : Peter W. Hochachka
Publisher : Unknown
Page : 208 pages
File Size : 50,6 Mb
Release : 1980
Category : Medical
ISBN : UOM:39015003217208

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Living Without Oxygen by Peter W. Hochachka Pdf

Innumerable clinical problems have as their basis some derangement in oxygen-dependent metabolism. To explore mechanisms of adjusting to oxygen limitation, Living without Oxygen presents a bestiary of exotic anaerobes that illuminate elements of metabolic biochemistry only dimly seen in studies using standard experimental animals. With their exaggerated anaerobic capabilities, Hochachka's diving mammals, airbreathing fishes, and hypoxia-adapted lower vertebrates allow a detailed assessment of what can and what cannot be adjusted in the process of extending hypoxia tolerance. The book places the enzymatic and biochemical machinery firmly in the biological context and assumes only a modest familiarity with bioenergetics and metabolic biochemistry. The author's clear prose should make this technical presentation pleasantly unintimidating for any physiologist, biochemist, or clinical investigator. The insights of his unique approach make Living without Oxygen essential reading.

Author : Sukhamay Lahiri,Gregg Semenza,Nanduri R. Prabhakar
Publisher : CRC Press
Page : 776 pages
File Size : 48,5 Mb
Release : 2003-04-15
Category : Medical
ISBN : 0824709608

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Oxygen Sensing by Sukhamay Lahiri,Gregg Semenza,Nanduri R. Prabhakar Pdf

Reviewing research on the molecular basis of oxygen homeostasis, this text describes the changes in intracellular signalling and gene expression that lead to physiological responses to hypoxia in unicellular, invertebrate, and mammalian species. It examines O2 sensing systems in bacteria and archaea and demonstrates interrelationships among cell proliferation, energy metabolism, oxygen homeostasis, redox states, signal transduction and gene expression in humans and other organisms. The book describes the effect of hypoxia on carotid body structure and function and the effect of alterations in oxygen homeostasis on the pathophysiology of cardiac ischemia, cancer, stroke, and chronic lung disease.

Author : Clare E. Elwell,Terence S. Leung,David K. Harrison
Publisher : Springer
Page : 537 pages
File Size : 45,8 Mb
Release : 2016-01-18
Category : Medical
ISBN : 9781493930234

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Oxygen Transport to Tissue XXXVII by Clare E. Elwell,Terence S. Leung,David K. Harrison Pdf

This book contains the refereed contributions from the 42nd annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. ISOTT conferences are a place where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 42nd annual meeting, which included sessions on: cellular hypoxia and mitochondria; blood substitutes and oxygen therapeutics; oxygen transport in critical care medicine and disease; muscle oxygenation; multi modal imaging techniques; brain oxygenation and imaging; optical techniques for oxygen measurement; microcirculation; mathematical modelling of oxygen transport; and cancer metabolism.

Author : D.L. Gilbert
Publisher : Springer Science & Business Media
Page : 414 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461258902

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Oxygen and Living Processes by D.L. Gilbert Pdf

The field of oxygen study is immense. No single work on the subject can be comprehensive, and this volume makes no such claim. Indeed, coverage here is selective and the selection is somewhat personal. However, the choice of topics is vast There are chapters on the history of oxygen, oxygen in the universe, the biochemistry of oxygen, and clinical uses of oxygen. An alternate title could have been, "Some things you always wanted to know about oxygen, but didn't know where to find them easily." Some information in this wide-ranging work can not be found elsewhere. This book is intended not only for specialists, but also for nonspecialists engaged in or curious about any field of oxygen study, particularly if they wish to know more about other fields of oxygen. Thus, those who are interested in oxygen and are historians, astronomers, chemists, geochemists, evolutionists, biochemists, physiolo gists, pathologists, or clinicians will find here much of extreme value. It is intended to be read and understood at the graduate or advanced undergraduate level. This volume is divided into four parts. The first constitutes the background for Parts II and III, and the last integrates the preceding material with an overall perspective on oxygen in living organisms.

Author : Amina A. Qutub
Publisher : Springer
Page : 350 pages
File Size : 49,5 Mb
Release : 2016-07-07
Category : Science
ISBN : 1441976396

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Systems Biology of Hypoxic Response and Angiogenesis by Amina A. Qutub Pdf

In this volume, the authors will describe the mechanisms of hypoxia and angiogenesis from a systems perspective. Hypoxia – defined as low oxygen – is quantitative by nature, and species dependent. Humans evolved to function in the Earth’s atmosphere of 21% O2. At even 1% lower atmospheric oxygen levels, the body responds with a host of mechanisms unactivated in normal oxygen levels. Oxygen levels in cells can be altered by multiple means, including changes in inspired oxygen, lack of oxygen-carrying hemoglobin from the blood, increased cellular oxygen demand and changes in the cell growth rates.

Author : Jeffrey G. Richards,Anthony P. Farrell,Colin J. Brauner
Publisher : Academic Press
Page : 517 pages
File Size : 41,7 Mb
Release : 2009-03-10
Category : Technology & Engineering
ISBN : 0080877990

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Fish Physiology: Hypoxia by Jeffrey G. Richards,Anthony P. Farrell,Colin J. Brauner Pdf

Periods of environmental hypoxia (Low Oxygen Availability) are extremely common in aquatic systems due to both natural causes such as diurnal oscillations in algal respiration, seasonal flooding, stratification, under ice cover in lakes, and isolation of densely vegetated water bodies, as well as more recent anthropogenic causes (e.g. eutrophication). In view of this, it is perhaps not surprising that among all vertebrates, fish boast the largest number of hypoxia tolerant species; hypoxia has clearly played an important role in shaping the evolution of many unique adaptive strategies. These unique adaptive strategies either allow fish to maintain function at low oxygen levels, thus extending hypoxia tolerance limits, or permit them to defend against the metabolic consequences of oxygen levels that fall below a threshold where metabolic functions cannot be maintained. The aim of this volume is two-fold. First, this book will review and synthesize the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure and place them within an environmental and ecological context. Second, through the development of a synthesis chapter this book will serve as the cornerstone for directing future research into the effects of hypoxia exposures on fish physiology and biochemistry. The only single volume available to provide an in-depth discussion of the adaptations and responses of fish to environmental hypoxia Reviews and synthesizes the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure Includes discussion of the evolutionary and ecological consequences of hypoxia exposure in fish

Author : David F. Wilson,Sydney M. Evans,John Biaglow,Anna Pastuszko
Publisher : Springer Science & Business Media
Page : 395 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461502050

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Oxygen Transport To Tissue XXIII by David F. Wilson,Sydney M. Evans,John Biaglow,Anna Pastuszko Pdf

The ISOTT 2001 local organizing committee was pleased to welcome over 140 delegates from around the world to the 29th annual general meeting of the International Society for Oxygen Transport to Tissue. The meeting was held in historic Philadelphia, USA, on the campus of the University of Pennsylvania from August 11 to 15, 2001. In the tradition of ISOTT, the conference was a total immersion experience. Attendees were encouraged to eat together and spend their evenings relaxing together in a style that maximized exchange of ideas and interactions of younger scientists with their more senior colleagues. Delegates participated in a total of 122 presentations including poster displays, selected oral presentations, seminars by invited speakers and a round table discussion. In choosing invited speakers and oral presenters, special emphasis was placed on methods for oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. All of the manuscripts contained in this volume underwent both an editorial and scientific review, and only those meeting both criteria have been published. However, while all efforts have been made to eliminate editorial errors, some have undoubtedly been overlooked, for which the editors apologize.

Author : Sukhamay Lahiri,Neil S Cherniak,Robert S Fitzgerald
Publisher : Springer
Page : 251 pages
File Size : 41,6 Mb
Release : 2013-05-27
Category : Medical
ISBN : 9781461475743

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Response and Adaptation to Hypoxia by Sukhamay Lahiri,Neil S Cherniak,Robert S Fitzgerald Pdf

The underlying theme of this book is the biology of oxygen. The 22 chapters cover aspects of molecular, cellular, and integrative physiological functions. A fundamental evolutionary feature of the oxygen-consuming organism is that it developed a oxygen-sensing mechanism as apart of feedback control at the levels of molecules, organelles, organs, and systems. Oxygen sensing is partic ularly expressed in certain specific cells and tissues like peripheral chemore ceptors, erythroprotein-producing cells, and vascular smooth muscle. Apart of the book is focused on the current issues of this basic question of chemosen sing. Mitrochondria as the major site for cellular oxygen consumption is a nat ural candidate for cellular oxygen sensitivity and adaptation. A section deals with this question. A perennial question concerns chronic environment al oxy gen and the organism's response and adaptation to it. This theme runs through several chapters. Because comparative physiology often provides insight into the mechanisms of environment al adaptation, a chapter on respiration of high altitude birds has been incorporated. Obviously this book gives only glimpses of the immense field of oxygen biology. The book grew out of two meetings where these subjects were discussed. These meetings were sponsored by the American Physiological Society and the Federation of American Societies for Experimental Biology. We are grateful to the FASEB Program Committee and APS publication committee for their sup port. We owe much to Ms. Anne Miller for her editorial assistance. S. L. Philadelphia N. S . C. Cleveland R. S. F.

Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 42,5 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781615047215

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Regulation of Tissue Oxygenation, Second Edition by Roland N. Pittman Pdf

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Author : Joost T. van Dongen,Francesco Licausi
Publisher : Springer Science & Business Media
Page : 419 pages
File Size : 42,9 Mb
Release : 2014-01-17
Category : Science
ISBN : 9783709112540

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Low-Oxygen Stress in Plants by Joost T. van Dongen,Francesco Licausi Pdf

During the last ten years, knowledge about the multitude of adaptive responses of plants to low oxygen stress has grown immensely. The oxygen sensor mechanism has been discovered, the knowledge about the interaction network of gene expression is expanding and metabolic adaptations have been described in detail. Furthermore, morphological changes were investigated and the regulative mechanisms triggered by plant hormones or reactive oxygen species have been revealed. This book provides a broad overview of all these aspects of low oxygen stress in plants. It integrates knowledge from different disciplines such as molecular biology, biochemistry, ecophysiology and agricultural / horticultural sciences to comprehensively describe how plants cope with low oxygen stress and discuss its ecological and agronomical consequences. This book is written for plant scientists, biochemists and scientists in agriculture and ecophysiology.

Author : Robert C. Roach,Peter D. Wagner,Peter H. Hackett
Publisher : Springer Science & Business Media
Page : 448 pages
File Size : 53,7 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9781475734010

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Hypoxia by Robert C. Roach,Peter D. Wagner,Peter H. Hackett Pdf

Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Author : Howard J. Halpern,Joseph C. LaManna,David K. Harrison,Boris Epel
Publisher : Springer
Page : 435 pages
File Size : 42,6 Mb
Release : 2017-07-06
Category : Medical
ISBN : 9783319552316

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Oxygen Transport to Tissue XXXIX by Howard J. Halpern,Joseph C. LaManna,David K. Harrison,Boris Epel Pdf

This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles. Both overview and the most recent, advanced techniques for oxygen measurement are presented. Articles and peer reviewers include those from leaders in their field. Topics such as molecular signaling in the organismal and tumor response to low levels of local oxygenation, hypoxia inducible factor (HIF) , cancer metabolism, individual human and animal response to oxygen changes monitored by optical/near infrared spectroscopy/ tomography to novel electron resonance spectroscopy and spectroscopic imaging, instrumentation, progress in blood substitute research, retinal physiology, cellular hypoxia, mitochondrial function; brain oxygenation and function; oxygen transport in sports, hypoxia in diseases and clinical care. Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.