Parasitic Infections And The Immune System

Author : Tracey Lamb
Publisher : John Wiley & Sons
Page : 531 pages
File Size : 49,8 Mb
Release : 2012-08-10
Category : Science
ISBN : 9781118393338

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Immunity to Parasitic Infection by Tracey Lamb Pdf

Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection. For easy reference, the most commonly studied parasites are examined in individual chapters written by investigators at the forefront of their field. An overview of the immune system, as well as introductions to protozoan and helminth parasites, is included to guide background reading. A historical perspective of the field of immunoparasitology acknowledges the contributions of investigators who have been instrumental in developing this field of research.

Author : Felipe Kierzenbaum
Publisher : Academic Press
Page : 280 pages
File Size : 40,5 Mb
Release : 1994
Category : Health & Fitness
ISBN : UOM:39015033086284

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Parasitic Infections and the Immune System by Felipe Kierzenbaum Pdf

Featuring the work of several world authorities, this volume places primary emphasis on the mechanism of parasite produced changes in the immune response (i.e. immunosuppression). The text covers parasitic diseases on which the World Health Organization has aggressively promoted research through its Program on Research and Training In Tropical Diseases. Chapters cover parasitic diseases such as malaria, American trypanosomiasis (Chagas' disease), African trypanosomiasis (sleeping sickness), leishmaniasis, schistosomiasis and onchocerciasis. Also included are discussions of toxoplasmosis and amebiasis. The material is drawn from the body of literature that has been rapidly accumulating for the last 15 years. An important feature of this text is that the contributors first outline existing knowledge about the immunology of each infection, thereby enabling the reader to more easily appreciate why and how the immunological alterations that accompany a disease are important, and then, to review the postulated mechanisms for such alterations. Consequently, the impact that each parasitic infection has on the immune system is always described in the "heart" of each chapter rather than at the beginning.

Author : Derek Wakelin
Publisher : Cambridge University Press
Page : 226 pages
File Size : 51,5 Mb
Release : 1996-08-13
Category : Medical
ISBN : 0521436354

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Immunity to Parasites by Derek Wakelin Pdf

Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.

Author : Felipe Kierzenbaum
Publisher : Academic Press
Page : 267 pages
File Size : 47,6 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9780080924052

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Parasitic Infections and the Immune System by Felipe Kierzenbaum Pdf

Featuring the work of several world authorities, this volume places primary emphasis on the mechanism of parasite produced changes in the immune response (i.e. immunosuppression). The text covers parasitic diseases on which the World Health Organization has aggressively promoted research through its Program on Research and Training In Tropical Diseases. Chapters cover parasitic diseases such as malaria, American trypanosomiasis (Chagas' disease), African trypanosomiasis (sleeping sickness), leishmaniasis, schistosomiasis and onchocerciasis. Also included are discussions of toxoplasmosis and amebiasis. The material is drawn from the body of literature that has been rapidly accumulating for the last 15 years. An important feature of this text is that the contributors first outline existing knowledge about the immunology of each infection, thereby enabling the reader to more easily appreciate why and how the immunological alterations that accompany a disease are important, and then, to review the postulated mechanisms for such alterations. Consequently, the impact that each parasitic infection has on the immune system is always described in the "heart" of each chapter rather than at the beginning.

Author : Genta
Publisher : Unknown
Page : 128 pages
File Size : 50,6 Mb
Release : 1996-03-01
Category : Electronic
ISBN : 0683034707

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Parasitic Infections and the Immune System by Genta Pdf

Author : Emilio Jirillo
Publisher : Immune Response to Parasitic I
Page : 196 pages
File Size : 41,5 Mb
Release : 2018-03-02
Category : Medical
ISBN : 1608056783

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Immune Response to Parasitic Infections by Emilio Jirillo Pdf

This book provides an interesting and up-to-date overview of Parasite Immunology in terms of a survival battle between hosts and parasites, describing firstly how parasites interact with different B cell compartments and trigger a vigorous antibody response. An Interesting chapter deals with new insights into immune diagnosis in Trypanosoma cruzi infection, while another chapter on malaria vaccines critically reviews their development since the beginning, examining the basis for failures or successes encountered in clinical trials. Chapters on immunological aspects of amoebiasis, giardiasis, toxoplasmosis and leishmaniasis in humans are written by top researchers in the world working in this field. This book should prove to be of interest to researchers and students wishing to familiarize themselves with the latest developments in this field. Therefore, this book is considered essential for all researchers involved in Infectious Diseases, Parasitology, Microbiology, Immunology, and Vaccine design and discovery.

Author : Abhay Prakash Mishra,Manisha Nigam
Publisher : John Wiley & Sons
Page : 436 pages
File Size : 52,7 Mb
Release : 2023-07-19
Category : Medical
ISBN : 9781119878025

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Parasitic Infections by Abhay Prakash Mishra,Manisha Nigam Pdf

Parasitic Infections Understand and defeat a scourge of public health with this cutting-edge guide Parasitic diseases are considered as an important public health problem due to the high morbidity and mortality rates, particularly in countries where climate and level of economic development create serious challenges to the creation of public health infrastructure, thus can make parasitic infections both graver and more difficult to contain. As we come to understand the global ramifications of public health, there has never been a more crucial time to understand these infections and the processes by which they can be managed and defeated. Parasitic Infections is a comprehensive overview of parasitic immunopathology, including the fundamentals of parasite biology, mechanisms and processes of infection, and the key steps of drug discovery and treatment. In addition to detailed coverage of the most commonly encountered infectious parasites, analysis of the immune system provides material pertinent to any possible parasitic infection. The result is an essential contribution to public health research. Parasitic Infections readers will also find: A careful balance of parasite immunopathology and pharmaceutical analysis Detailed discussion of parasites such as protozoans, helminths, and ectoparasites Case studies and in-depth analyses written by authors around the world on the basis of first hand investigation Parasitic Infections is a must-read for researchers or professionals in immunology, biology, medicinal chemistry, drug development or pharmaceutical research, and all related fields.

Author : Toni Aebischer,Kai Matuschewski,Susanne Hartmann
Publisher : Frontiers Media SA
Page : 294 pages
File Size : 52,7 Mb
Release : 2018-07-06
Category : Electronic
ISBN : 9782889454853

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Parasite Infections: From Experimental Models to Natural Systems by Toni Aebischer,Kai Matuschewski,Susanne Hartmann Pdf

Eukaryotic parasites (including parasitic protozoans, worms and arthropods) are more complex and heterogeneous organisms than pathogenic bacteria and viruses. This notion implies different evolutionary strategies of host exploitation. Typically, parasites establish long-term infections and induce relatively little mortality, as they often limit pathological changes by modulating host cells and downregulating adverse immune responses. Their pattern of distribution tends to be endemic rather than epidemic. Despite these seemingly benign traits, parasites usually cause substantial chronic morbidity, thus constituting an enormous socioeconomic burden in humans, particularly in resource poor countries, and in livestock worldwide. Parasite-induced fitness costs are an evolutionary force that can shape populations and contribute to species diversity. Therefore, a thorough understanding of parasites and parasitic diseases requires detailed knowledge of the respective biochemical, molecular and immunological aspects as well as of population genetics, epidemiology and ecology. This Research Topic (RT) bridges disciplines to connect molecular, immunological and wildlife aspects of parasitic infections. The RT puts emphases on four groups of parasites: Plasmodium, Toxoplasma, Giardia and intestinal helminths. Co-infections are also covered by the RT as they represent the most common form of parasite infections in wildlife and domestic animal populations. Within the four types of parasites the following topics are addressed: (1) Experimental models: hypothesis testing, translation and limits. (2) Critical appraisal of experimental models. (3) Natural systems: Technological advances for investigations in natural parasite-host systems and studies in natural systems. (4) The urgent need for better models and methods in natural parasite systems. Hence, the RT covers and illustrate by the means of four main parasitic infections the parasite-host system at the molecular, cellular and organismic level.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 55,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Xun Suo,Hyun Soon Lillehoj,Wenbin Tuo,Zhiguang Wu
Publisher : Frontiers Media SA
Page : 429 pages
File Size : 40,9 Mb
Release : 2020-06-25
Category : Electronic
ISBN : 9782889638017

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Immunoparasitology: A Unique Interplay Between Host and Pathogen by Xun Suo,Hyun Soon Lillehoj,Wenbin Tuo,Zhiguang Wu Pdf

Author : Faith H. A. Osier,Jude Ezeh Uzonna
Publisher : Frontiers Media SA
Page : 187 pages
File Size : 40,7 Mb
Release : 2020-07-24
Category : Electronic
ISBN : 9782889638741

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Regulation of Immunity to Parasitic Infections Endemic to Africa by Faith H. A. Osier,Jude Ezeh Uzonna Pdf

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.

Author : Shailendra K. Saxena,Hridayesh Prakash
Publisher : BoD – Books on Demand
Page : 416 pages
File Size : 44,7 Mb
Release : 2021-08-25
Category : Medical
ISBN : 9781838807658

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Innate Immunity in Health and Disease by Shailendra K. Saxena,Hridayesh Prakash Pdf

The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.

Author : Emilio Jirillo,Thea Magrone,Giuseppe Miragliotta
Publisher : Bentham Science Publishers
Page : 269 pages
File Size : 48,7 Mb
Release : 2014-10-29
Category : Medical
ISBN : 9781608059850

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Immunity to Helminths and Novel Therapeutic Approaches by Emilio Jirillo,Thea Magrone,Giuseppe Miragliotta Pdf

This volume covers research on the interaction of major helminth parasites with the immune system. The main focus of the e-book is the ability of helminths to subvert host immune responses, on the one hand. On the other hand, the immunological armamentarium of the host against invading parasites is described also in the light of new findings on innate and adaptive immunity. These include the discovery of a new category of lymphocytes, innate lymphoid cells, and the role of T helper cels such as Th1, Th2 and Th3 cells, T regulatory (Treg) and Th17 cells in helminth diseases and inflammation. The balance between these two T cell subsets during the various stages of helminth diseases is also discussed. The book concludes with a review of new therapeutic approaches to combat helminth parasites (biotherapy, vaccines and natural products). Immunity to Helminths and Novel Therapeutic Approaches provides updated information for medical students, clinicians and researchers in the fields of parasitology, applied immunology and novel drug delivery.

Author : Steven A. Frank
Publisher : Princeton University Press
Page : 364 pages
File Size : 53,6 Mb
Release : 2002-07-21
Category : Medical
ISBN : 0691095957

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Immunology and Evolution of Infectious Disease by Steven A. Frank Pdf

Publisher Description

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 55,5 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.