Perinatal Stem Cells

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Perinatal Stem Cells

Author : Anthony Atala,Kyle J. Cetrulo,Rouzbeh R. Taghizadeh,Curtis L Cetrulo,Sean Murphy
Publisher : Academic Press
Page : 418 pages
File Size : 44,9 Mb
Release : 2018-06-14
Category : Science
ISBN : 9780128120637

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Perinatal Stem Cells by Anthony Atala,Kyle J. Cetrulo,Rouzbeh R. Taghizadeh,Curtis L Cetrulo,Sean Murphy Pdf

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells

Perinatal Stem Cells

Author : Kyle Cetrulo,Curtis L. Cetrulo, Jr.,Rouzbeh R. Taghizadeh
Publisher : John Wiley & Sons
Page : 438 pages
File Size : 40,7 Mb
Release : 2013-02-04
Category : Science
ISBN : 9781118497944

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Perinatal Stem Cells by Kyle Cetrulo,Curtis L. Cetrulo, Jr.,Rouzbeh R. Taghizadeh Pdf

Perinatal Stem Cells, 2nd Edition builds on the first edition to provide an updated tutorial on perinatal stem cells, including stem cells harvested from the amniotic fluid, placenta, maternal blood supply, umbilical cord and Wharton's Jelly. As in the first edition, coverage includes the underlying biology of each of the sources of pregnancy related stem cells, cell culture, and potential therapeutic uses, as well as insights on the impact of these stem cells from obstetricians and gynecologists, cardiologists, hematologists, tissue engineers, and cord blood bankers. Normally discarded as medical waste, perinatal stem cells offer a powerful therapeutic tool box alternative to the controversial embryonic stem cells. Since publication of the first edition, a burgeoning commerical industry has developed around various sources of perinatal cells, and the second edition now includes an overview of this growing industry. With contributions from some of the top academic stem cell laboratories in the United States as well as new chapters from international stem cell scientists, Perinatal Stem Cells presents an update on the cutting-edge research in the field while maintaining its signature clinical focus.

Perinatal Stem Cells

Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
Publisher : Springer
Page : 0 pages
File Size : 40,6 Mb
Release : 2019-03-25
Category : Health & Fitness
ISBN : 9811327025

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Perinatal Stem Cells by Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li Pdf

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton’s Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.

Perinatal Stem Cells

Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
Publisher : Springer
Page : 173 pages
File Size : 51,9 Mb
Release : 2019-03-06
Category : Health & Fitness
ISBN : 9789811327032

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Perinatal Stem Cells by Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li Pdf

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton’s Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.

Perinatal Tissue-Derived Stem Cells

Author : Babak Arjmand
Publisher : Springer
Page : 239 pages
File Size : 43,5 Mb
Release : 2016-12-01
Category : Science
ISBN : 9783319464107

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Perinatal Tissue-Derived Stem Cells by Babak Arjmand Pdf

This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy.

Fetal Stem Cells in Regenerative Medicine

Author : Dario O. Fauza,Mahmud Bani
Publisher : Springer
Page : 453 pages
File Size : 42,6 Mb
Release : 2016-05-02
Category : Science
ISBN : 9781493934836

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Fetal Stem Cells in Regenerative Medicine by Dario O. Fauza,Mahmud Bani Pdf

This book explores the regenerative properties of fetal stem cells, from feto-maternal cell traffic through perinatal stem cells, with a discussion of key topics including stem cell banking, drug screening, in utero stem cell transplantation and ethical considerations. The expertly authored chapters also delve into embryonic, amniotic membrane, and umbilical cord blood stem cells; fetal development models; fetal cell reprogramming; culture methods; disease models; perinatal gene therapy, and more. These chapters are grouped into four sections, each discussing a separate prenatal stem cell population and providing fascinating historical contexts for our knowledge of these systems. Featuring a foreword written by the renowned Dr. Joseph Vacanti of the Harvard Stem Cell Institute, Fetal Stem Cells in Regenerative Medicine: Principles and Translational Strategies is a welcome and timely contribution to the Stem Cell Biology and Regenerative Medicine series. It is essential reading for scientists and researchers, clinicians and residents, and advanced students involved in stem cells, regenerative medicine, tissue engineering, and related disciplines such as embryology.

Stem cells: From Potential to Promise

Author : Khawaja Husnain Haider
Publisher : Springer Nature
Page : 285 pages
File Size : 52,9 Mb
Release : 2021-10-04
Category : Science
ISBN : 9789811603013

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Stem cells: From Potential to Promise by Khawaja Husnain Haider Pdf

The book highlights the therapeutic applications of various stem cells, and introduces readers to thymus stem cells and their applications in the reconstitution of thymic structure and function. It also discusses the significant role of mesenchymal stem cells (MSCs) in the treatment of autoimmune diseases and the use of MSC-derived exosomes in cell-free therapy. Moreover, it explores the application of hematopoietic stem cells in the vasculoprotection of the ischemially injured heart. Further topics include the regenerative potential of ovarian germline stem cells and the significance of endometrial stem cells in the pathogenesis of female reproductive tract diseases. Lastly, the book addresses stem cells from perinatal tissues and their immunoregulatory and differentiation potentials, and summarizes new strategies for targeting cancer stem cells to treat tumors.

Cell Therapy for Perinatal Brain Injury

Author : Haruo Shintaku,Akira Oka,Makoto Nabetani
Publisher : Springer
Page : 150 pages
File Size : 51,6 Mb
Release : 2018-03-01
Category : Medical
ISBN : 9789811014123

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Cell Therapy for Perinatal Brain Injury by Haruo Shintaku,Akira Oka,Makoto Nabetani Pdf

This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.

Placenta

Author : Ornella Parolini
Publisher : CRC Press
Page : 395 pages
File Size : 41,9 Mb
Release : 2016-02-22
Category : Medical
ISBN : 9781498788175

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Placenta by Ornella Parolini Pdf

Long regarded as biological waste, the placenta is gaining momentum as a viable product for clinical use. Due to their unique properties, placental cells and derivatives show great promise in curing various diseases. Utilizing contributions from world-renowned experts, Placenta: The Tree of Life considers the therapeutic potential of these cells. I

Stem Cells and Bone Tissue

Author : Rajkumar Rajendram,Victor R. Preedy,Vinood Patel
Publisher : CRC Press
Page : 424 pages
File Size : 44,8 Mb
Release : 2013-01-23
Category : Medical
ISBN : 9781466578418

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Stem Cells and Bone Tissue by Rajkumar Rajendram,Victor R. Preedy,Vinood Patel Pdf

Stem cells potentially offer a novel therapeutic platform to treat bone disease. They also help the scientist understand the molecular and cellular aetiology of bone disorders. Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. Stem Cells and Bone Tissue is designed to address these areas in three sections: Introductory Text and Sources of Stem Cells for Skeletal Tissue Cellular and Molecular Aspects Conditions, Applications, Treatments and Repairs Coverage includes general aspects of stems cells, sources of stems cells, isolation and purification, applications in regeneration, nanoscale topography, myostatin (GDF-8) signalling, c-Jun, Lnk, cell-derived Factor 1/CXCR4, chromatin remodelling, osteoporosis, osteoarthritis, hypophosphatasia, osteopetrosis, osteogenesis, and many other areas of merit too numerous to mention.

Stem Cells

Author : Rob Burgess
Publisher : John Wiley & Sons
Page : 380 pages
File Size : 55,6 Mb
Release : 2016-01-19
Category : Science
ISBN : 9781118439197

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Stem Cells by Rob Burgess Pdf

Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others. Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.

Mesenchymal Stem Cells in Human Health and Diseases

Author : Ahmed El-Hashash
Publisher : Academic Press
Page : 230 pages
File Size : 41,8 Mb
Release : 2020-01-07
Category : Science
ISBN : 9780128205334

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Mesenchymal Stem Cells in Human Health and Diseases by Ahmed El-Hashash Pdf

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Stem Cells and Biomaterials for Regenerative Medicine

Author : Marek J. Los,Andrzej Hudecki,Emilia Wiechec
Publisher : Academic Press
Page : 249 pages
File Size : 49,5 Mb
Release : 2018-11-07
Category : Science
ISBN : 9780128122785

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Stem Cells and Biomaterials for Regenerative Medicine by Marek J. Los,Andrzej Hudecki,Emilia Wiechec Pdf

Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials

Stem Cells

Author : Ariff Bongso,Eng Hin Lee
Publisher : World Scientific
Page : 721 pages
File Size : 48,6 Mb
Release : 2011
Category : Science
ISBN : 9789814289382

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Stem Cells by Ariff Bongso,Eng Hin Lee Pdf

Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Advances in Tissue Engineering

Author : Julia Polak,Sakis Mantalaris,Sian E Harding
Publisher : World Scientific
Page : 948 pages
File Size : 42,8 Mb
Release : 2008-08-20
Category : Science
ISBN : 9781908978905

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Advances in Tissue Engineering by Julia Polak,Sakis Mantalaris,Sian E Harding Pdf

Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field. Contents:Tissue Engineering: Past, Present and Future:An Introduction (R M Nerem)Cells for Tissue Engineering:A Brief Introduction to Different Cell Types (L Buttery & K M Shakesheff)Human Embryonic Stem Cells: International Policy and Regulation (M Allyse & S Minger)Human Embryonic Stem Cells: Derivation and Culture (E L Stephenson et al.)Stem Cells Differentiation (P V Guillot & W Cui)Marrow Stem Cells (D G Phinney)Cord Blood Stem Cells — Potentials and Realities (C P McGuckin & N Forraz)Fat Stem Cells (J M Gimble et al.)Control of Adult Stem Cell Function in Bioengineered Artificial Niches (M P Lutolf & H M Blau)Stem Cell Immunology (A P Hollander & D C Wraith)Development of a Design of Experiment Methodology: Applications to the Design and Analysis of Experiments (M Lim & A Mantalaris)Banking Stem Cell Lines for Future Therapies (G N Stacey & C J Hunt)Materials:Synthetic Biomaterials as Cell-Responsive Artificial Extracellular Matrices (M P Lutolf & J A Hubbell)Bioactive Composite Materials for Bone Tissue Engineering Scaffolds (S Verrier & A R Boccaccini)Aggregation of Cells Using Biomaterials and Bioreactors (Z Bayoussef & K M Shakesheff)Nanotechnology for Tissue Engineering (J S Stephens-Altus & J L West)Microscale Technologies for Tissue Engineering (A Khademhosseini et al.)Non-Invasive Methods to Monitor Tissue Re-Modelling: Biosensors(T Cass)Tissue-Engineering Monitoring Using Microdialysis (Z-H Li et al.)Characterisation of Tissue Engineering Constructs by Raman Spectroscopy and X-ray Micro-Computed Tomography (μCT) (I Notingher & J R Jones)Role of Stem Cell Imaging in Regenerative Medicine (G Passacquale & K Bhakoo)Biotechnology Sector:Lessons Learnt (N L Parenteau et al.)The Promise of Stem Cells: A Venture Capital Perspective (C Prescott)Tissue Engineering Products:Cell Expansion, Cell Encapsulation, 3D Cultures (J M Polak & A Mantalaris)Bioreactor Engineering: Regenerating the Dynamic Cell Microenvironment (T Dvir & S Cohen)UK Regulatory Issues: The View from the Researcher (C Munro & N Harris)Tissue Repair:Stem Cell Therapy: Past, Present, and Future (F Baron & R Storb)Tissue Engineered Skin Comes of Age? (S MacNeil)Liver Repair (N Levicar et al.)Tissue Engineering for Tooth Regeneration (I A Diakonov & P Sharpe)Urogenital Repair (A Atala)Cardiac Repair:Basic Science (S E Harding)Cardiac Repair Clinical Trials (A Green & E Alton)Myocardial Recovery Following LVAD Support (R S George & E J Birks)Osteoarticular Repair:Animal Models (E A Horner et al.)In Vitro 3D Human Tissue Models for Osteochondral Diseases (S Ghosh & D L Kaplan)Application of Tissue Engineering for Craniofacial Reconstruction (D M Gupta et al.)Clinical Trials (A K Haudenschild & M H Hedrick)Lung Repair:Tissue Engineering for the Respiratory Epithelium: Is There a Future for Stem Cell Therapy in the Lung? (V Besnard & J A Whitsett)The Artificial Lung (A N Maurer & G Matheis) Readership: Stem cell researchers, clinicians, surgeons and biotechnology companies. Keywords:Stem Cells;Tissue Engineering;Regenerative Medicine;BiomaterialsKey Features:Discusses in-depth a topical subject, treated with the very latest informationWritten by leading contributors in the field, with the world-renowned Professor Dame Julia Polak as the lead editorContains an array of color diagrams and illustrationsDiffers from competing titles in that its coverage ranges from the basic science of stem cells and biomaterials to clinical applications, policy issues, views from the commercial sector and many others