Pharmacology Toxicology

Author : Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj
Publisher : Springer Nature
Page : 1156 pages
File Size : 43,6 Mb
Release : 2021-03-13
Category : Medical
ISBN : 9789813360099

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Introduction to Basics of Pharmacology and Toxicology by Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj Pdf

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Author : Gerard Marshall Raj,Ramasamy Raveendran
Publisher : Springer Nature
Page : 410 pages
File Size : 45,6 Mb
Release : 2019-11-16
Category : Medical
ISBN : 9789813297791

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Introduction to Basics of Pharmacology and Toxicology by Gerard Marshall Raj,Ramasamy Raveendran Pdf

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Author : Mr. A. V. Yadav
Publisher : Pragati Books Pvt. Ltd.
Page : 324 pages
File Size : 41,9 Mb
Release : 2008-10-07
Category : Electronic
ISBN : 818579023X

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Pharmacology & Toxicology by Mr. A. V. Yadav Pdf

Author : Melanie Johns Cupp
Publisher : Springer Science & Business Media
Page : 407 pages
File Size : 46,6 Mb
Release : 2000-02-03
Category : Medical
ISBN : 9781592590209

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Toxicology and Clinical Pharmacology of Herbal Products by Melanie Johns Cupp Pdf

The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Herbai remedies are for sale not just in health food stores, but in supermar kets, drug stores, and even discount warehouses. Along with the proliferation in sales has come a proliferation ofinformation sources. Not all ofthe sources are equally reliable, or even intelligible. Traditional herbalists c1assify thistle and mugwort as "cholagogues," substances used to make the gallbladder con tract and release bile. Medical school graduates are unlikely to have ever heard the term, or even accept the notion that most right-sided abdominal pain is a result of diminished bile flow. Heroin and cocaine may not be the only drugs to come from plants, but a practicing physician or toxicologist might be forgiven for thinking so. In 1998, 1264 papers were published about cocaine and only 17 about kava kava, an abused herb that is not without toxic side effects. Unfortunately, the majority of the papers about kava kava were published in journals not found in ordi nary hospitallibraries. In recognition ofthis fact, and ofthe obvious need for a reliable reference work on herbai toxicology, The Toxicology and Clinical Pharmacology 0/ Herbal Products was an early addition to our new series in Forensie Science and Medicine. It is very badly needed.

Author : Ethan B Russo
Publisher : Routledge
Page : 482 pages
File Size : 42,5 Mb
Release : 2013-09-05
Category : Health & Fitness
ISBN : 9781136614934

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Cannabis and Cannabinoids by Ethan B Russo Pdf

Study the latest research findings by international experts! This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world’s foremost researchers. Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. This book discusses the scientific basis for marijuana’s use in cases of pain, nausea, anorexia, and cachexia. It also explores its possible benefits in glaucoma, ischemia, spastic disorders, and migraine. Cannabis and Cannabinoids examines all facets of the medical use of marijuana, including: botany history biochemistry pharmacology clinical use toxicology side effects Cannabis and Cannabinoids is a reference work that will become indispensable to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public. No other book available offers this comprehensive, even-handed look at a deeply divisive subject.

Author : Rudy J Richardson,Dale E Johnson
Publisher : Royal Society of Chemistry
Page : 332 pages
File Size : 49,8 Mb
Release : 2017-03-01
Category : Science
ISBN : 9781788011204

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Computational Systems Pharmacology and Toxicology by Rudy J Richardson,Dale E Johnson Pdf

The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics. This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.

Author : R D Budhiraja
Publisher : Popular Prakashan
Page : 532 pages
File Size : 54,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 8179914720

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Elementary Pharmacology & Toxicology 4e by R D Budhiraja Pdf

Author : Pharmacology-Toxicology Program (National Institute of General Medical Sciences)
Publisher : Unknown
Page : 126 pages
File Size : 47,6 Mb
Release : 1978
Category : Pharmacology
ISBN : CHI:62458228

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Annual Report - National Institute of General Medical Sciences, Pharmacology-Toxicology Program by Pharmacology-Toxicology Program (National Institute of General Medical Sciences) Pdf

Author : Edward J. Massaro
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 42,6 Mb
Release : 2002-07-01
Category : Medical
ISBN : 9781592592883

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Handbook of Copper Pharmacology and Toxicology by Edward J. Massaro Pdf

Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease.

Author : Abby Calvin
Publisher : Unknown
Page : 0 pages
File Size : 49,5 Mb
Release : 2016-06-02
Category : Pharmacology
ISBN : 1682861910

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Textbook of Pharmacology and Toxicology by Abby Calvin Pdf

Toxicology forms an integral part of pharmacology. It plays a crucial role in drug development as well. This book integrates the applications of toxicology and pharmacology through researches collected from across the globe. Some of the areas covered in this book are drug safety, drug interactions, drug reaction and monitoring, evaluation of drugs, ecotoxicology, etc. This text will prove to be a beneficial resource material for students, scholars, pharmacologists, researchers and anyone else who wants to delve deeper into the advancements in pharmacology and toxicology.

Author : Paul I. Dargan,David M. Wood
Publisher : Academic Press
Page : 556 pages
File Size : 44,6 Mb
Release : 2021-09-06
Category : Medical
ISBN : 9780128190302

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Novel Psychoactive Substances by Paul I. Dargan,David M. Wood Pdf

Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. Includes chapters written by international experts in the field Presents a comprehensive overview on the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene, including amphetamines and the synthetic cannabinoid receptors in ‘spice’ and ‘K2’

Author : National Institute of General Medical Sciences (U.S.). Pharmacology and Toxicology Training Committee
Publisher : Unknown
Page : 140 pages
File Size : 49,9 Mb
Release : 1968
Category : Drugs
ISBN : MSU:31293011964875

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Status of Research in Pharmacology and Toxicology by National Institute of General Medical Sciences (U.S.). Pharmacology and Toxicology Training Committee Pdf

Author : Ali S. Faqi
Publisher : Elsevier
Page : 1074 pages
File Size : 47,5 Mb
Release : 2024-02-11
Category : Medical
ISBN : 9780323984621

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A Comprehensive Guide to Toxicology in Nonclinical Drug Development by Ali S. Faqi Pdf

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Author : Robert M. Featherstone
Publisher : Unknown
Page : 456 pages
File Size : 49,9 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015000868482

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A Guide to Molecular Pharmacology-toxicology by Robert M. Featherstone Pdf

Author : Hans H. Maurer,Simon D. Brandt
Publisher : Springer
Page : 566 pages
File Size : 51,7 Mb
Release : 2019-02-20
Category : Medical
ISBN : 9783030105617

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New Psychoactive Substances by Hans H. Maurer,Simon D. Brandt Pdf

This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.