Pharmacovigilance For Herbal And Traditional Medicines

Author : Joanne Barnes
Publisher : Springer Nature
Page : 406 pages
File Size : 46,8 Mb
Release : 2022-08-11
Category : Science
ISBN : 9783031072758

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Pharmacovigilance for Herbal and Traditional Medicines by Joanne Barnes Pdf

This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines. Taking a truly global perspective, this volume draws together contributions from a diverse group of experts, writing on current knowledge and practices in pharmacovigilance for herbal and traditional medicines, and on advances and innovation in monitoring the safety of this unique and complex category of products and preparations. In part one, the book discusses the current status of pharmacovigilance for herbal and traditional medicines, including the importance of natural products chemistry to harms, and its relevance in considering how pharmacovigilance for these products could be undertaken. Several other chapters discuss methodological approaches and ongoing challenges in pharmacovigilance for herbal and traditional medicines, including issues relating to nomenclature, coding and classification, and the nuances involved in causality assessment. Part two of the book focusses on pharmacovigilance for herbal and traditional medicines around the world, with chapters from authors in several different countries representing diverse historical, ethnic, cultural, social and political contexts. These chapters provide deeper insights and perspectives into spontaneous reporting for herbal and traditional medicines in those countries, and in the context of the local use, practice and regulatory landscape for these products. Part two also provides an overview and new analysis of international case safety reports for herbal medicines held in VigiBase (the World Health Organization's global database of individual case safety reports, maintained by the Uppsala Monitoring Centre). This book is aimed at pharmacists, doctors, nurses and other health professionals, herbal-medicine practitioners and organisations, herbal medicine and pharmaceutical industry personnel, pharmacovigilance specialists, medicines’ regulators, health and social science researchers and academics, pharmacovigilance and health professional students, and students of herbal and traditional medicine, throughout the world. It is an extremely valuable resource for all individuals whose work touches the intersection between herbal medicines and pharmacovigilance, and it provides both an introduction to the topic and a deeper, comprehensive, contemporary account of the topic.

Author : World Health Organization
Publisher : Unknown
Page : 18 pages
File Size : 51,6 Mb
Release : 2004-01-01
Category : Drug monitoring
ISBN : 9241592214

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WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems by World Health Organization Pdf

Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.

Author : Subhash C. Mandal,Raja Chakraborty,Saikat Sen
Publisher : Springer Nature
Page : 1135 pages
File Size : 46,8 Mb
Release : 2021-01-18
Category : Medical
ISBN : 9789811581274

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Evidence Based Validation of Traditional Medicines by Subhash C. Mandal,Raja Chakraborty,Saikat Sen Pdf

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine.

Author : Gerard Bodeker,Gemma Burford
Publisher : World Scientific
Page : 472 pages
File Size : 55,8 Mb
Release : 2007
Category : Medical
ISBN : 9781860949135

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Traditional, Complementary and Alternative Medicine by Gerard Bodeker,Gemma Burford Pdf

This is the first book to address public health issues in traditional, complementary and alternative medicine (TCAM). It presents state-of-the-art reviews of TCAM research in a range of priority public health areas such as malaria and HIV and in such common ailments as skin conditions and orthopedic injury in developing countries. Contributions analyze policy trends in areas such as financing of TCAM and education and training in this field as well as selected case studies of model TCAM projects. Important chapters on research methodology, ethical and safety issues, and intellectual property rights pertaining to traditional medicine are also presented. Public financing for TCAM is a test of the commitment of governments, and the book includes an analysis from the World Health Organization's (WHO) Global Atlas data of the worldwide trends in this area. With safety concerns foremost in the minds of both policy makers and the public, the book offers a global overview of policy and legislative trends in this field as well as an important set of guidelines for pharmacovigilance and TCAM products. Sample Chapter(s). Chapter 1: Introduction (1,729 KB). Contents: Foreword (Allan Rosenfield); Policy: Introduction (Gerard Bodeker & Gemma Burford); Policy and Public Health Perspectives on Traditional, Complementary and Alternative Medicine: An Overview (Gerard Bodeker, Fredi Kronenberg & Gemma Burford); Financing Traditional, Complementary and Alternative Health Care Services and Research (Gemma Burford, Gerard Bodeker & Chi-Keong Ong); Training (Gerard Bodeker, Cora Neumann, Chi-Keong Ong & Gemma Burford); Safety: Issues and Policy (Gilbert Shia, Barry Noller & Gemma Burford); Pharmacovigilance of Herbal Medicines: A United Kingdom Perspective (Joanne Barnes); Medicinal Plant Biodiversity and Local Healthcare: Sustainable Use and Livelihood Development (Gerard Bodeker & Gemma Burford); Home Herbal Gardens OCo A Novel Health Security Strategy Based on Local Knowledge and Resources (G Hariramamurthi, P Venkatasubramanian, P M Unnikrishnan & D Shankar); Humanitarian Responses to Traditional Medicine for Refugee Care (Cora Neumann & Gerard Bodeker); Public-Private Partnerships: A Case Study from East Africa (Patrick Mbindyo); Public Health Issues: Priority Diseases and Health Conditions: Malaria (Merlin L Willcox & Gerard Bodeker); HIV/AIDS: Traditional Systems of Health Care in the Management of a Global Epidemic (Gerard Bodeker, Gemma Burford, Mark Dvorak-Little & George Carter); An Overview of Clinical Studies on Complementary and Alternative Medicine in HIV Infection and AIDS (Jianping Liu); Skin and Wound Care: Traditional, Complementary and Alternative Medicine in Public Health Dermatology (Gemma Burford, Gerard Bodeker & Terence J Ryan); Traditional Orthopaedic Practices: Beyond OCyBonesettingOCO (Gemma Burford, Gerard Bodeker & Jonathan Cohen); Research: Clinical Trial Methodology (Ranjit Roy Chaudhury, Urmila Thatte & Jianping Liu); Ethical Issues in Research (Merlin L Willcox, Gerard Bodeker & Ranjit Roy Chaudhury); Intellectual Property Rights (Gerard Bodeker); Epilogue (Gerard Bodeker & Gemma Burford). Readership: Public health specialists and departments; health policy departments in ministries of health and universities; colleges of traditional and complementary medicine; World Health Organization and affiliated institutions; medical schools as a background text on TCAM."

Author : Andrew Bate
Publisher : Humana
Page : 0 pages
File Size : 54,9 Mb
Release : 2018-10-26
Category : Medical
ISBN : 1493988166

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Evidence-Based Pharmacovigilance by Andrew Bate Pdf

This book examines insights into the latest thinking and core concepts in areas of key methodological endeavor in Pharmacovigilance (PV), which strives to ever more effectively protect patients from harm caused by the medicines they need. Each book chapter tends to have a clear quantitative or clinical slant and an aim to provide an overview of methodological insights within a specific topic, while also providing a perspective on how the area is anticipated to develop in the future. Quantitative chapters focus more on statistical and epidemiological strategies and the thinking that underpins core developments in Pharmacovigilance, whereas clinical chapters focus on clinical methods for detecting hypotheses for and determining side effects of medicinal products as well as misdiagnosis pitfalls. Examples of areas of importance include signal detection, risk management, and risk benefit assessment. Vital and authoritative, Evidence-Based Pharmacovigilance: Clinical and Quantitative Aspects aims to provide readers with a sense of the advances that have occurred in pharmacovigilance methods and approaches, as well as inspiration and motivation to advance the field of pharmacovigilance with a strong sense that there is much more work to be done in ensuring the safe use of medications by patients.

Author : Saikat Sen,Raja Chakraborty
Publisher : Springer Nature
Page : 612 pages
File Size : 46,9 Mb
Release : 2019-09-10
Category : Medical
ISBN : 9789811372483

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Herbal Medicine in India by Saikat Sen,Raja Chakraborty Pdf

This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating the drug discovery process. The book also provides in-depth information on various traditional medicinal systems in India and discusses their medical importance. India has a very long history of safely using many herbal drugs. Folk medicine is also a key source of medical knowledge and plays a vital role in maintaining health in rural and remote areas. Despite its importance, this form of medicine largely remains under-investigated. Out of all the traditional medicinal systems used worldwide, Indian traditional medicine holds a unique position, as it has continued to deliver healthcare throughout the Asian subcontinent since ancient times. In addition, traditional medicine has been used to derive advanced techniques and investigate many modern drugs. Given the scope of its coverage, the book offers a valuable resource for scientists and researchers exploring traditional and herbal medicine, as well as graduate students in courses on traditional medicine, herbal medicine and pharmacy.

Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 858 pages
File Size : 44,8 Mb
Release : 2022-07-12
Category : Business & Economics
ISBN : 9780323984560

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Evidence-Based Validation of Herbal Medicine by Pulok K. Mukherjee Pdf

Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Author : José Luis Valverde
Publisher : IOS Press
Page : 216 pages
File Size : 41,7 Mb
Release : 1999
Category : Business & Economics
ISBN : 1586030051

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The Problem of Herbal Medicines Legal Status by José Luis Valverde Pdf

The main problem in the use of medicinal plants, discussed in this book, is that citizens are being persuaded that herbal medicine is based on its low or even absent toxicology. A good efficacy is assumed as self-evident, and therapeutic benefit without risks is expected. Many users prefer natural medicine instead of synthetic remedies. However, the number of reports on unwanted side effects of phytomedicines increased in the last years. In some instances, a lack of pharmaceutical quality was found. The unqualified recommendation of herbal medicines may represent a considerable risk to the user. The use of a herbal remedy with unproven efficacy can represent a risk for the user when a more effective and necessary treatment will therefore be stopped or omitted. These circumstances must be taken into account by the governments, inspection services, the doctors and the judges. The present approach to herbal medicines and fraud with these products do not receive the necessary punishment because it is believed that if the product does not have any therapeutic property, it cannot entail any harm either.

Author : Anonim
Publisher : World Health Organization
Page : 85 pages
File Size : 40,8 Mb
Release : 2021-05-19
Category : Medical
ISBN : 9789240019140

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Key technical issues of herbal medicines with reference to interaction with other medicines by Anonim Pdf

This document provides information on the critical technical issues related to interactions between herbal medicines and other medicines for health-care professionals, regulators, researchers, pharmacovigilance centres, manufacturers and consumers. The intention of this document is to provide as much concise information as possible, and to give direction and guidance on capitalizing resources to support informed decision-making and maximize the safe concurrent use of herbal medicines and other medicines. The concepts of beneficial and harmful herb-drug interaction (HDI)s are introduced, with documented examples from the published literature. Types of HDI and their mechanisms are outlined, and the relevance of in vitro, general screening and in vivo tests is included. Challenges faced in evaluating and monitoring HDIs, data collection, assessment and dissemination of information are briefly discussed. The education and training of health professionals and consumers are addressed, together with potential research strategies for further investigation of the mechanisms, incidence, monitoring and management of HDIs.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 44,9 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:879065272

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Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene by Anonim Pdf

Author : Anita Lavorgna,Anna Di Ronco
Publisher : Routledge
Page : 232 pages
File Size : 51,8 Mb
Release : 2019-10-18
Category : Health & Fitness
ISBN : 9780429754982

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Medical Misinformation and Social Harm in Non-Science Based Health Practices by Anita Lavorgna,Anna Di Ronco Pdf

Fraudulent, harmful, or at best useless pharmaceutical and therapeutic approaches developed outside science-based medicine have boomed in recent years, especially due to the commercialisation of cyberspace. The latter has played a fundamental role in the rise of false ‘health experts’, and in the creation of filter bubbles and echo chambers that have contributed to the formation of highly polarised debates on non-science-based health practices—online as well as offline. By adopting a multidisciplinary approach, this edited book brings together contributions of international academics and practitioners from criminology, digital sociology, health psychology, medicine, law, physics, and journalism, where they critically analyse different types of non-science-based health approaches. With this volume, we aim to reconcile different scientific understandings of these practices, synthesising a variety of empirical, theoretical and interpretative approaches, and exploring the challenges, implications and potential remedies to the spread of dangerous and misleading health information. This edited book will offer some food for thought not only to students and academics in the social sciences, health psychology and medicine among other disciplines, but also to medical practitioners, science journalists, debunkers, policy makers and the general public, as they might all benefit from a greater awareness and critical knowledge of the harms caused by non-scientific health practices.

Author : World Health Organization,Council for International Organizations of Medical Sciences,Cioms
Publisher : Unknown
Page : 381 pages
File Size : 51,7 Mb
Release : 2001-01-01
Category : Medical
ISBN : 9290360747

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Current Challenges in Pharmacovigilance by World Health Organization,Council for International Organizations of Medical Sciences,Cioms Pdf

In spite of recent progress in the harmonization of terminology and processes affecting work on the clinical safety of medicines consensus is needed on standards for many difficult aspects of day-to-day pharmacovigilance that continue to pose problems for both the pharmaceutical industry and drug regulators. The CIOMS V Working Group has generated proposals for pragmatic approaches to dealing with such issues as: classification and handling of individual safety case reports from a variety of sources (spontaneous consumer reports solicited reports literature the Internet observational studies and secondary data bases disease and other registries regulatory ADR databases and licensor-licensee interactions); new approaches to case management and regulatory reporting practices (proper clinical evaluation of cases incidental vs other events patient and reporter identifiability seriousness criteria expectedness criteria case follow-up criteria and the role and structure of case narratives); improvements and efficiencies in the format content and reporting of periodic safety update reports (PSURs) (including results of an industry survey on PSUR workloads and practices; proposals for high case volume and long time-period reports simplification of certain PSURs summary bridging reports addendum reports license renewal reports for EU and Japan dealing with old products and other technical details); determination and use of population exposure (denominator) data (sources of data and a guide to analytical approaches for a variety of circumstances).The Group has also taken stock of the current state of expedited and periodic clinical safety reporting requirements around the world with summary data on regulations from more than 60 countries. Recommendations are made for enhancing the harmonization steps already taken as a result of previous CIOMS publications and the ICH process. In addition to dealing with unfinished and unresolved issues from previous CIOMS initiatives the report covers many emerging topics such as those involving new technologies. Its 20 Appendices provide a wealth of detailed explanations and reference information. It is the most comprehensive and recent treatment of difficult pharmacovigilance issues affecting the working practices and systems of drug safety and other pharmaceutical professionals.

Author : Simon Y Mills,Kerry Bone
Publisher : Elsevier Health Sciences
Page : 704 pages
File Size : 43,9 Mb
Release : 2004-12-23
Category : Medical
ISBN : 9780443071713

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The Essential Guide to Herbal Safety by Simon Y Mills,Kerry Bone Pdf

Winner of American Botanical Council's 2005 James A. Duke Botanical Literature Award, the Essential Guide to Herbal Safety offers a balanced and objective perspective on the principles of herbal medicine safety as well as the complex challenges relating to self-prescribed or professionally prescribed herbal medications and supplements. With contributions from leading international practitioners and authorities, it contains comprehensive reviews, in monograph format, of the published safety data for 125 common herbs. You'll also find coverage of issues of quality, interactions, adverse reactions, toxicity, allergy, contact sensitivity, and idiosyncratic reactions. Provides the most current information on safety issues in herbal medicine. Presents authoritative and credible safety information from two experienced herbal practitioners. Combines theoretical chapters with 125 well-researched monographs, making it the most thorough and comprehensive text on the market for herbal safety in practice. Provides clear information using the most current evidence-based reviews, covering factors that influence herb safety, including the negative placebo effects (nocebo), various types of unpredictable effects, the basis for interactions between herbs and drugs, and quality issues. Uses an established grading system for assessing safety in pregnancy and lactation that is realistic and appropriate to herb use. Thoroughly critiques the dominant misinformation in the media and medical journals on herb safety issues. Contains 83 documented case studies on hepatoxicity and the effects in relation to kava. Kava safety is a hot topic. Includes two useful appendices detailing herbal references for pregnancy and lactation considerations.

Author : Jon Adams,Gavin Andrews,Joanne Barnes
Publisher : Bloomsbury Publishing
Page : 312 pages
File Size : 50,8 Mb
Release : 2017-09-16
Category : Medical
ISBN : 9781137265593

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Traditional, Complementary and Integrative Medicine by Jon Adams,Gavin Andrews,Joanne Barnes Pdf

This authoritative collection is the first wide-ranging overview dedicated to traditional, complementary and integrative medicine (TCIM) and its scientific study. Compiled by an expert editorial team, it is an essential guide to the vast and ever-growing international literature on TCIM. Contributions come from practitioners and academics drawn from a diverse range of disciplines and professions across the globe. From perspectives on the significance of TCIM within public health policy to discourses on its influence in fields such as psychiatry and sociology, discrete chapters come together to provide an international map of the contemporary research, key debates and core issues which shape the field. Carefully structured to ensure easy navigation, the reader is divided into three parts: - Part A focuses on the consumption of TCIM, including chapters on its use through the life-cycle and within the context of disease and health management - Part B covers considerations for practitioners across the world, taking in issues over ethics, communication and education - Part C features chapters on the role of evidence, research and knowledge production in TCIM and looks at what lies ahead for the field With its thought-provoking insights and suggestions for further reading, this comprehensive resource provides guidance and inspiration for anyone embarking on study, practice or research within health, nursing or medicine.

Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 784 pages
File Size : 44,6 Mb
Release : 2019-05-30
Category : Science
ISBN : 9780128133989

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Quality Control and Evaluation of Herbal Drugs by Pulok K. Mukherjee Pdf

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities