Philosophy Of Systems Biology

Author : Sara Green
Publisher : Springer
Page : 265 pages
File Size : 54,7 Mb
Release : 2016-12-15
Category : Science
ISBN : 9783319470009

Get Book

Philosophy of Systems Biology by Sara Green Pdf

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.

Author : Fred Boogerd,Frank J. Bruggeman,Jan-Hendrik S. Hofmeyr,H.V. Westerhoff
Publisher : Elsevier
Page : 360 pages
File Size : 53,8 Mb
Release : 2007-03-20
Category : Computers
ISBN : 0080475272

Get Book

Systems Biology by Fred Boogerd,Frank J. Bruggeman,Jan-Hendrik S. Hofmeyr,H.V. Westerhoff Pdf

Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies. * Answers the question of what distinguishes the living from the non-living * An in-depth look to a vigorous and expanding discipline, from molecule to system * Explores the region between individual components and the system

Author : Fred C. Boogerd
Publisher : Unknown
Page : 0 pages
File Size : 43,9 Mb
Release : 2007
Category : Electronic
ISBN : OCLC:1027941248

Get Book

Systems Biology by Fred C. Boogerd Pdf

Author : Peter Godfrey-Smith
Publisher : Princeton University Press
Page : 200 pages
File Size : 44,7 Mb
Release : 2016-09-06
Category : Philosophy
ISBN : 9780691174679

Get Book

Philosophy of Biology by Peter Godfrey-Smith Pdf

An essential introduction to the philosophy of biology This is a concise, comprehensive, and accessible introduction to the philosophy of biology written by a leading authority on the subject. Geared to philosophers, biologists, and students of both, the book provides sophisticated and innovative coverage of the central topics and many of the latest developments in the field. Emphasizing connections between biological theories and other areas of philosophy, and carefully explaining both philosophical and biological terms, Peter Godfrey-Smith discusses the relation between philosophy and science; examines the role of laws, mechanistic explanation, and idealized models in biological theories; describes evolution by natural selection; and assesses attempts to extend Darwin's mechanism to explain changes in ideas, culture, and other phenomena. Further topics include functions and teleology, individuality and organisms, species, the tree of life, and human nature. The book closes with detailed, cutting-edge treatments of the evolution of cooperation, of information in biology, and of the role of communication in living systems at all scales. Authoritative and up-to-date, this is an essential guide for anyone interested in the important philosophical issues raised by the biological sciences.

Author : Kostas Kampourakis
Publisher : Springer Science & Business Media
Page : 765 pages
File Size : 42,7 Mb
Release : 2013-06-18
Category : Philosophy
ISBN : 9789400765375

Get Book

The Philosophy of Biology by Kostas Kampourakis Pdf

This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.

Author : Stephen Krawetz
Publisher : Springer Science & Business Media
Page : 639 pages
File Size : 54,8 Mb
Release : 2008-12-11
Category : Science
ISBN : 9781597454407

Get Book

Bioinformatics for Systems Biology by Stephen Krawetz Pdf

Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.

Author : Brian Garvey
Publisher : Routledge
Page : 320 pages
File Size : 48,7 Mb
Release : 2014-12-05
Category : Philosophy
ISBN : 9781317493662

Get Book

Philosophy of Biology by Brian Garvey Pdf

This major new series in the philosophy of science aims to provide a new generation of textbooks for the subject. The series will not only offer fresh treatments of core topics in the theory and methodology of scientific knowledge, but also introductions to newer areas of the discipline. Furthermore, the series will cover topics in current science that raise significant foundational issues both for scientific theory and for philosophy more generally. Biology raises distinct questions of its own not only for philosophy of science, but for metaphysics, epistemology and ethics. This comprehensive new textbook for a rapidly growing field of study provides students new to the subject with an up-to-date presentation of the key philosophical issues. Care is taken throughout to keep the technicalities accessible to the non-biologist but without sacrificing the philosophical subtleties. The first part of the book covers the philosophical challenges posed by evolution and evolutionary biology, beginning with Darwin's central argument in the Origin of the Species. Individual chapters cover natural selection, the selfish gene, alternative units of selection, developmental systems theory, adaptionism and issues in macroevolution. The second part of the book examines philosophical questions arising in connection with biological traits, function, nature and nurture, and biological kinds. The third part of the book examines metaphysical questions, biology's relation with the traditional concerns of philosophy of science, and how evolution has been introduced into epistemological debates. The final part considers the relevance of biology to questions about ethics, religion and human nature.

Author : A. D. Breck
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 47,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468419658

Get Book

Biology, History, and Natural Philosophy by A. D. Breck Pdf

In a world that peers over the brink of disaster more often than not it is difficul t to find specific assignments for the scholarly community. One speaks of peace and brotherhood only to realize that for many the only real hope of making a contribution may seem to be in a field of scientific specialization seemingly irrelevant to social causes and problems. Yet the history of man since the beginnings of science in the days of the Greeks does not support this gloomy thesis. Time and again we have seen science precipitate social trends or changes in the humanistic beliefs that have a significant effect on. the scientific community. Not infrequently the theoretical scientist, triggered by society's changing goals and understandings, finds ultimate satisfaction in the work of his colleagues in engineering and the other applied fields. Thus the major debate in mid-nineteenth century in which the evidence of natural history and geology at variance with the Biblical feats provided not only courage to a timid Darwin but the kind of audience that was needed to fit his theories into the broad public dialogue on these topics. The impact of "Darwinism" was felt far beyond the scientific community. It affected social thought, upset religious certainties and greatly affected the teaching of science.

Author : John Dupré
Publisher : Oxford University Press
Page : 361 pages
File Size : 50,6 Mb
Release : 2012-01-26
Category : Philosophy
ISBN : 9780199691982

Get Book

Processes of Life by John Dupré Pdf

John Dupré explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and society. He reveals how the advance of genetic science is changing our view of the constituents of life, and shows how an understanding of microbiology will overturn standard assumptions about the living world.

Author : Cécilia Bognon-Küss,Charles T. Wolfe
Publisher : Routledge
Page : 220 pages
File Size : 42,5 Mb
Release : 2019-02-11
Category : Social Science
ISBN : 9781317227557

Get Book

Philosophy of Biology Before Biology by Cécilia Bognon-Küss,Charles T. Wolfe Pdf

The use of the term "biology" to refer to a unified science of life emerged around 1800 (most prominently by scientists such as Lamarck and Treviranus, although scholarship has indicated its usage at least 30-40 years earlier). The interplay between philosophy and natural science has also accompanied the constitution of biology as a science. Philosophy of Biology Before Biology examines biological and protobiological writings from the mid-eighteenth century to the early nineteenth century (from Buffon to Cuvier; Kant to Oken; and Kielmeyer) with two major sets of questions in mind: What were the distinctive conceptual features of the move toward biology as a science? What were the relations and differences between the "philosophical" focus on the nature of living entities, and the "scientific" focus? This insightful volume produces a fresh but also systematic perspective both on the history of biology as a science and on the early versions of, in the 1960s in a post-positivist context, the philosophy of biology. It will appeal to students and researchers interested in fields such as history of science, philosophy of science and biology.

Author : Thomas W. Polger,Lawrence A. Shapiro
Publisher : Oxford University Press
Page : 273 pages
File Size : 48,6 Mb
Release : 2016
Category : FAMILY & RELATIONSHIPS
ISBN : 9780198732891

Get Book

The Multiple Realization Book by Thomas W. Polger,Lawrence A. Shapiro Pdf

Thomas W. Polger and Lawrence A. Shapiro provide a full investigation of multiple realisation - the idea that minds can be realised in ways other than the human brain. They cast doubt on the hypothesis and give an alternative framework for understanding explanations in the cognitive sciences, and in chemistry, biology, and related fields.

Author : James A. Marcum
Publisher : Unknown
Page : 252 pages
File Size : 42,8 Mb
Release : 2020-07-09
Category : Systems biology
ISBN : 1536179604

Get Book

From Systems Biology to Systems Medicine by James A. Marcum Pdf

Throughout most of the twentieth century, the biomedical model dominated healthcare. However, the biomedical model had its critics, who proposed alternative models to replace it. Eventually, biomedicine became fragmented at its foundations with a variety of approaches to its nature and practice. Medicine's current response to this fragmentation is to combine these disparate approaches into a single system--systems medicine. In the present book, I examine the shift, during the postgenomics era, from the biomedical model to systems medicine vis-à-vis systems biology, as well as the challenges facing systems medicine's implementation in the twenty-first century. The main goal of the present book is to provide a disciplinary framework for examining the rise of systems medicine, especially in terms of the incorporation of systems biology into the biomedical model. To realize that goal, the following questions are addressed. What is a disciplinary framework? And, why is this framework important for understanding systems biology and medicine? Briefly, a disciplinary framework represents the relational structure among disparate disciplines that support and ground a discipline and its corpus. For traditional biology and medicine, that framework consists of various disciplines within the biological and biomedical sciences, including physiology, neuroscience, pathology, and epidemiology--to name a few. For the present purpose, systems biology within the last several decades is reshaping the disciplinary framework of the biological and biomedical sciences, which is also responsible for the emergence of systems medicine. In addition, the challenges facing systems medicine, especially its operationalization and implementation with respect to medical education and practice, as well as research, are also explored.

Author : Martin Döring,Imme Petersen,Anne Brüninghaus,Regine Kollek
Publisher : Springer
Page : 316 pages
File Size : 51,5 Mb
Release : 2015-12-18
Category : Science
ISBN : 9783319171067

Get Book

Contextualizing Systems Biology by Martin Döring,Imme Petersen,Anne Brüninghaus,Regine Kollek Pdf

This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists working in the interdisciplinary areas of systems biology, synthetic biology, molecular biology, biology, the philosophy of science, the sociology of science and scientific knowledge, science and technology studies, technology assessment and the like. The authors of this monograph share the theoretical methodological premise that science is a culturally and socially embedded practice which characterizes our culture as a scientific one and at the same time draws its innovative potential from its socio-cultural context. This dialectic relationship lies at the heart of the current development of systems biology which is conceived as a so-called successor of ‘-omics’ research and triggered by high-throughput information technologies. At the same time a need for a holistic conceptualization of complex biological processes emerges. The title Contextualizing Systems Biology suggests that this book analyzes the development and advent of systems biology from different theoretical and methodological perspectives. We investigate a variety of contexts ranging from the analysis of cognitive contexts (such as basic theoretical concepts) to regulative contexts (policies) to the concrete application of a systems biology in the socio-scientific context of a European research project. In empirically analyzing these different and interrelated layers and dimensions of systems biology, the scope of the book goes beyond present attempts to investigate the advent of new approaches in the biological sciences as it frames and assesses systems biology from an interdisciplinary and integrated perspective.

Author : Pavel Kraikivski
Publisher : Springer Nature
Page : 310 pages
File Size : 51,6 Mb
Release : 2021-10-06
Category : Science
ISBN : 9783030677428

Get Book

Case Studies in Systems Biology by Pavel Kraikivski Pdf

This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relevant details with regard to cell physiology and molecular mechanisms? How are the details put together into a mathematical model? How is the model analyzed and simulated? What are the results of the model? How do they compare to the known facts of the cell physiology? Does the model make predictions? What can be done to extend the model? The book presents a summary of results and references to more relevant sources. The volume contains the classic collection of topics and studies that are well established yet novel in the systems biology field.

Author : Alvaro Moreno,Matteo Mossio
Publisher : Springer
Page : 221 pages
File Size : 49,6 Mb
Release : 2015-05-04
Category : Philosophy
ISBN : 9789401798372

Get Book

Biological Autonomy by Alvaro Moreno,Matteo Mossio Pdf

Since Darwin, Biology has been framed on the idea of evolution by natural selection, which has profoundly influenced the scientific and philosophical comprehension of biological phenomena and of our place in Nature. This book argues that contemporary biology should progress towards and revolve around an even more fundamental idea, that of autonomy. Biological autonomy describes living organisms as organised systems, which are able to self-produce and self-maintain as integrated entities, to establish their own goals and norms, and to promote the conditions of their existence through their interactions with the environment. Topics covered in this book include organisation and biological emergence, organisms, agency, levels of autonomy, cognition, and a look at the historical dimension of autonomy. The current development of scientific investigations on autonomous organisation calls for a theoretical and philosophical analysis. This can contribute to the elaboration of an original understanding of life - including human life - on Earth, opening new perspectives and enabling fecund interactions with other existing theories and approaches. This book takes up the challenge.