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Author : Jeffrey W. Hand,James R. James
Publisher : Unknown
Page : 558 pages
File Size : 43,9 Mb
Release : 1986
Category : Cancer
ISBN : 0863800378
Author : Bhudatt R. Paliwal,Fred W. Hetzel,Mark Dewhirst
Publisher : American Institute of Physics
Page : 506 pages
File Size : 42,6 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015018970619
While the establishment of hyperthermia as a routine therapy awaits the results of ongoing controlled clinical trials, the advancement in biological sciences, physics and engineering, clinical physics and dosimetry, as well as clinical implementation continues to make advances. A first attempt to document these advances was made by Dr. Gilbert H. Nussbaum in the Medical Physics Monograph No. 8 of the American Association of Physicists in Medicine, published by the American Institute of Physics in 1982. This monograph is an extension of the above work. The material is divided into six catagories: Hyperthermia Biology, Physics and Engineering, Clinical Physics, Dosimetry and Modeling, Analysis of Clinical Results, and Quality Assurance. There are numerous methods of inducing hyperthermia and there are also equally numerous clinical strategies as expected in an experimental modality. A conscious effort has been made to document the basic information and thus provide an objective learning tool. The material contained herein will be of interest to biologists, physicists, engineers, and physicians who are actively involved in the field of hyperthermia, as well as to those who are anxious to learn about this new field. Some sections provide extremely practical information needed in the routine delivery of treatments and, therefore, will be of benefit to nurses and technologists. We also believe that this material provides insight and guidance for future research.
Author : Michel Gautherie
Publisher : Springer Science & Business Media
Page : 130 pages
File Size : 40,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642746369
The enormous potential that hyperthermia has for benefiting patients with cancer is impressively indicated by biological studies, both in vitro and in vivo, and by comparative clinical studies whenever the heat has been appro priate to the size of the tumor. But hyperthermia, as with any other technologically based medical procedures, requires an extensive develop ment of sophisticated instrumentation and techniques to offer routine clinical benefit. We probably erred in starting clinical trials so soon. We had hoped that by showing the clinical benefits on some superficial tumors quickly, financial support would be stimulated for the required technolog ical developments. Unfortunately, treating superficial disease adequately was more difficult than we had supposed and regional treatments were less successful than we had wished. The physical reasons are clear and were apparent from the beginning, although in our enthusiasm we ignored them. Circumstances are different now. We have to treat a wide range of tumors in various sites, but the systems and techniques required are only available in a few laboratories and clinics where they still are undergoing refinement.
Author : Gian F. Baronzio,E. Dieter Hager
Publisher : Springer Science & Business Media
Page : 382 pages
File Size : 54,7 Mb
Release : 2008-05-08
Category : Medical
ISBN : 9780387334417
Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.
Author : Gilbert H. Nussbaum
Publisher : American Institute of Physics
Page : 0 pages
File Size : 41,6 Mb
Release : 1998-03-31
Category : Science
ISBN : 0883184141
Over the past several years, interest and activity regarding the use of heat to treat human malignancies has grown very rapidly. Laboratory studies with cells and animals have established the potential of hyperthermia, used alone, or in combination with radiation or drugs, for improvement of the therapeutic ratio in cancer therapy. A growing body of clinical data suggests that hyperthermia, employed as an adjuvant and perhaps, as a primary therapeutic modality, can often effect rapid and substantial tumor regression while causing only relatively modest changes in adjacent normal tissues. Given the clinical observations to date and the rationale provided by biological and physiological laboratory investigations, the current, prodigious growth of clinical utilization of hyperthermia in surgical, medical and especially radiation oncology is not difficult to comprehend. However, the development of clinical hyperthermia as a safe, effective and quantitative cancer modality will depend critically on the extent to which the physics and physiology of local, regional and whole body heating of human tissue are understood and properly incorporated into the planning and administration of thermotherapy. Whatever its promise, ultimately, the value of hyperthermia as a clinical tool will be governed, and perhaps limited by the physical aspects of power deposition, heat transfer and thermometry in vivo. This book discusses this important topic in depth.
Author : Stanley B. Field,Jeffrey W. Hand
Publisher : Taylor & Francis Group
Page : 600 pages
File Size : 42,9 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015019597775
Hyperthermia combined with either radiation or chemotherapy is rapidly becoming a clinical reality in many institutions as a form of treatment of malignant disease. This is an introduction to the subject aimed at the total audience, but particularly clinicians.
Author : M.Heinrich Seegenschmiedt,Peter Fessenden,Clare C. Vernon
Publisher : Springer Science & Business Media
Page : 479 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642578588
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
Author : Leopold J. Anghileri,Jacques Robert
Publisher : CRC Press
Page : 390 pages
File Size : 46,9 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9781000012682
First published in 1986, Hyperthermia in Cancer Treatment is a most useful guide to the relationship between Hyperthermia, and the ways in which it is used for the control of cancer. Well-structured and comprehensive, this book is a must-read for any students of Oncology or professionals in their respective fields
Author : Tadayoshi Matsuda
Publisher : Taylor & Francis
Page : 420 pages
File Size : 50,6 Mb
Release : 1993
Category : Cancer
ISBN : 0850668379
This work describes the ways in which the techniques of hyperthermia have been used in a project in Japanese oncology clinics since 1984. The physical, biological and clinical aspects of hyperthermic oncology are detailed.
Author : Clifford L. K. Pang
Publisher : CRC Press
Page : 347 pages
File Size : 40,8 Mb
Release : 2015-05-26
Category : Medical
ISBN : 9780429586200
Hyperthermia in oncology is the application of heat to a patient's body for the purpose of cancer treatment. In recent years, its use has seen rapid development, with a large amount of clinical data becoming available. Hyperthermia in Oncology synthesizes the current research on the topic and provides treatment protocols for using localized as well
Author : Webb
Publisher : Oxford University Press
Page : 1961 pages
File Size : 52,9 Mb
Release : 2020-01-10
Category : Medical
ISBN : 9780198855439
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Author : Andras Szasz,Nora Szasz,Oliver Szasz
Publisher : Springer Science & Business Media
Page : 575 pages
File Size : 42,9 Mb
Release : 2010-11-23
Category : Medical
ISBN : 9789048194988
Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.
Author : James Lin
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 41,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468480597
Ever since the early 1940's, electromagnetic energy in the nonionizing spectrum has contributed to the enhanced quality of life in a variety of ways. Aside from their well-known roles in communication, entertainment, industry and science, electromagnetic energy has come into wide spread use in biology and medicine. In addition to the intended purposes, these energies produce other effects which have been shown to influence the life processes of living organisms. It is noteworthy that these energies are not only harmless in ordinary quantities but are actually necessary for modern life, indeed without which life as we know it would be impossible. The purpose of this book is to present a succinct summary of the interaction of electromagnetic fields and waves with biological systems as they are now known. The subject matter is interdisciplinary and is based primarily on presentations scheduled for a joint symposium at the XXII General Assembly of the International Union of Radio Science, held in Tel Aviv, Israel from Tuesday, August 25 to Wednesday, September 2, 1987. The symposium was jointly sponsored by the Bioelectromagnetics Society in cooperation with the International Radiation Protection Association. The choice of topics was made to facilitate the application and to stimulate the use of nonioni zing electromagnetic energy in biology and medicine, and to increase the awareness and to promote the consideration of radiation safety by electrical engineers and experimental physicists.
Author : G. Bruggmoser,W. Hinkelbein,R. Engelhardt,M. Wannenmacher
Publisher : Springer
Page : 143 pages
File Size : 54,6 Mb
Release : 2011-12-30
Category : Medical
ISBN : 3642825311
The present challenge in the treatment of tumors is to reduce the number of patients that still die as a result of primary tumors. Today, the percentage of such deaths remains high at 30%, even when all the common therapeutic methods, namely surgery, radiotherapy, and chemotherapy, are applied. In order to reduce this percentage, new types of radiation sources with a higher linear energy transfer have been intro duced, such as neutrons and pions. Fractionation patterns have been modified and radiosensitizers have been applied to in crease biological efficiency. Studies of the combined application of chemotherapy and radiotherapy have been made to find the best therapeutic effect. In the early 1970s biological findings confirmed the effect of hyperthermia on tumor cells. The first clinical studies on hyper thermia treatment demonstrated that it resulted in better local tumor control. Further application of this treatment modality showed that hyperthermia should be used in addition to radio therapy and chemotherapy. Despite these encouraging results, hyperthermia has not been introduced into common clinical use, due primarily to technical problems. There are a number of methods of transferring heat into tumors; however, with regard to physical conditions, an op timum method has not yet been found. One of the reasons is that up to now we have had no reliable method of obtaining thermal mapping of all parts of the human body. Such measurements are required not only for dosimetric purposes but also for the regula tion of a hyperthermic system.
Author : Leonard L. Gunderson, MD, MS, FASTRO,Joel E. Tepper, MD
Publisher : Elsevier Health Sciences
Page : 2253 pages
File Size : 45,6 Mb
Release : 2015-08-26
Category : Medical
ISBN : 9780323240987
Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.