Pituitary Disorders Of Childhood

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Pituitary Disorders of Childhood

Brenda Kohn
Pituitary Disorders of Childhood Book PDF

Author : Brenda Kohn
Publisher : Springer
Page : 362 pages
File Size : 51,8 Mb
Release : 2019-03-27
Category : Medical
ISBN : 9783030113391

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Pituitary Disorders of Childhood by Brenda Kohn Pdf

This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.

Pituitary Disorders of Childhood

Brenda Kohn
Pituitary Disorders of Childhood Book PDF

Author : Brenda Kohn
Publisher : Unknown
Page : 362 pages
File Size : 46,5 Mb
Release : 2019
Category : Endocrinology
ISBN : 303011340X

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Pituitary Disorders of Childhood by Brenda Kohn Pdf

This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.

Gigantism and Acromegaly

Constantine A. Stratakis
Gigantism and Acromegaly Book PDF

Author : Constantine A. Stratakis
Publisher : Academic Press
Page : 312 pages
File Size : 43,6 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9780128145388

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Gigantism and Acromegaly by Constantine A. Stratakis Pdf

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism

Neuroendocrine Disorders in Children

Mehul T. Dattani,Peter Hindmarsh,Lucinda Carr,Iain Robinson
Neuroendocrine Disorders in Children Book PDF

Author : Mehul T. Dattani,Peter Hindmarsh,Lucinda Carr,Iain Robinson
Publisher : Mac Keith Press
Page : 0 pages
File Size : 50,5 Mb
Release : 2016-11-07
Category : Medical
ISBN : 1909962503

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Neuroendocrine Disorders in Children by Mehul T. Dattani,Peter Hindmarsh,Lucinda Carr,Iain Robinson Pdf

Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children. These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others. Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed. This volume will become invaluable reading for paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians. Sections in the book cover The GH-IGF1 axis and the brain The thyroid axis and the brain Regulation of appetite and weight Effects of treatment of cancer on the neuroendocrine system Adrenal disorders and the brain Neuroendocrinology and the reproductive axis Neurological complications of diabetes mellitus

Brook's Clinical Pediatric Endocrinology

Mehul T. Dattani,Charles G. D. Brook
Brook s Clinical Pediatric Endocrinology Book PDF

Author : Mehul T. Dattani,Charles G. D. Brook
Publisher : John Wiley & Sons
Page : 816 pages
File Size : 48,6 Mb
Release : 2019-11-04
Category : Medical
ISBN : 9781119152682

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Brook's Clinical Pediatric Endocrinology by Mehul T. Dattani,Charles G. D. Brook Pdf

The seventh edition of Brook's Clinical Pediatric Endocrinology has been compiled by an experienced editorial team and internationally renowned contributors; it presents basic science and clinical management of endocrine disorders for all involved in the care of children and adolescents. It provides treatments for a variety of hormonal diseases, including diabetes and hypoglycaemia, growth problems, thyroid disease and disorders of puberty, sexual differentiation, calcium metabolism, steroid metabolism and hypopituitarism.

Pediatric Endocrinology

Sally Radovick,Margaret H. MacGillivray
Pediatric Endocrinology Book PDF

Author : Sally Radovick,Margaret H. MacGillivray
Publisher : Springer Science & Business Media
Page : 624 pages
File Size : 46,7 Mb
Release : 2013-02-20
Category : Medical
ISBN : 9781607613954

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Pediatric Endocrinology by Sally Radovick,Margaret H. MacGillivray Pdf

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

Pituitary Disorders throughout the Life Cycle

Susan L. Samson,Adriana G. Ioachimescu
Pituitary Disorders throughout the Life Cycle Book PDF

Author : Susan L. Samson,Adriana G. Ioachimescu
Publisher : Springer Nature
Page : 399 pages
File Size : 42,8 Mb
Release : 2022-08-25
Category : Medical
ISBN : 9783030999186

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Pituitary Disorders throughout the Life Cycle by Susan L. Samson,Adriana G. Ioachimescu Pdf

The pituitary gland is often referred to as the master gland, coordinating hormonal signals from the hypothalamus and peripheral circulation to maintain homeostasis in the body. Patients with pituitary dysfunction are faced with challenges unique to each stage of their life cycle. For example, the goals of management for a hypopituitary adolescent transitioning to adulthood would be to optimize growth and sexual development. In early adulthood, approaches that optimize of fertility in men and women can be a priority, and the management approach will be very different from that of older adults requiring sex hormone replacement. This case-based guide will provide practical clinical guidance on approaches to the management of pituitary disorders organized by time of life, from childhood and fertile years through to older age. Sensibly divided into sections, various pituitary disorders and conditions are described and relevant treatment strategies are outlined. Sections included discussions of the unique considerations for the pituitary gland in childhood and adolescents, patients desiring fertility and pregnant patients, health optimization and non-tumoral diagnoses in adults, and management of disorders of the hypothalamic-pituitary axis in the elderly. Each chapter presents a clinical case vignette as an introduction to the concepts and a framework for the discussion of the diagnosis, management and unique consideration of each pituitary pathology. Practical and user-friendly, Pituitary Disorders throughout the Life Cycle is an excellent resource for practicing clinical endocrinologists (pediatric, transitional care, adult) and reproductive endocrinologists as well as specialty residents and trainees.

Growth Hormone Deficiency in Adults

Jens O. L. Jørgensen,Jens Sandahl Christiansen
Growth Hormone Deficiency in Adults Book PDF

Author : Jens O. L. Jørgensen,Jens Sandahl Christiansen
Publisher : Karger Medical and Scientific Publishers
Page : 241 pages
File Size : 46,9 Mb
Release : 2005-01-01
Category : Science
ISBN : 9783805579926

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Growth Hormone Deficiency in Adults by Jens O. L. Jørgensen,Jens Sandahl Christiansen Pdf

It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.

Pediatric Endocrinology

M. Sperling
Pediatric Endocrinology Book PDF

Author : M. Sperling
Publisher : Unknown
Page : 826 pages
File Size : 49,6 Mb
Release : 2002
Category : Medical
ISBN : UOM:39015055194545

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Pediatric Endocrinology by M. Sperling Pdf

This New Edition is today's most comprehensive, definitive reference in the field, incorporating all of today's explosive discoveries in basic and clinical endocrinology. Its reliable, cutting-edge guidance for a full range of problems is combined with a wealth of information on the physiological, biochemical, and genetic basis at the molecular biological level. Dr. Mark A. Sperling and 33 contributing experts bring readers the benefits of discovery at the bench and its application at the bedside. New chapters, extensive revisions, and compelling updates will keep readers at the forefront of the diagnosis and management of endocrine disease in children. Incorporates the explosive growth in molecular biology as it relates to developmental and pediatric endocrinology. Extensively revised and updated chapters throughout reflect the latest information. Coverage of up-to-the-minute topics in the field, including molecular, biochemical, and clinical basis of hyperinsulinemic hypoglycemia of infancy and childhood diabetes mellitus energy balance/obesity growth hormone paradigms of mechanisms of hormone action, and others Contributions from new authors from distinguished institutions Numerous brand-new illustrations depict the most current information, particularly the basic science/genetic basis of certain entities

Cerebral Palsy

Freeman Miller,Steven J. Bachrach
Cerebral Palsy Book PDF

Author : Freeman Miller,Steven J. Bachrach
Publisher : JHU Press
Page : 537 pages
File Size : 49,7 Mb
Release : 2006-05-08
Category : Health & Fitness
ISBN : 9780801883545

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Cerebral Palsy by Freeman Miller,Steven J. Bachrach Pdf

When a child has a health problem, parents want answers. But when a child has cerebral palsy, the answers don't come quickly. A diagnosis of this complex group of chronic conditions affecting movement and coordination is difficult to make and is typically delayed until the child is eighteen months old. Although the condition may be mild or severe, even general predictions about long-term prognosis seldom come before the child's second birthday. Written by a team of experts associated with the Cerebral Palsy Program at the Alfred I. duPont Hospital for Children, this authoritative resource provides parents and families with vital information that can help them cope with uncertainty. Thoroughly updated and revised to incorporate the latest medical advances, the second edition is a comprehensive guide to cerebral palsy. The book is organized into three parts. In the first, the authors describe specific patterns of involvement (hemiplegia, diplegia, quadriplegia), explain the medical and psychosocial implications of these conditions, and tell parents how to be effective advocates for their child. In the second part, the authors provide a wealth of practical advice about caregiving from nutrition to mobility. Part three features an extensive alphabetically arranged encyclopedia that defines and describes medical terms and diagnoses, medical and surgical procedures, and orthopedic and other assistive devices. Also included are lists of resources and recommended reading.

Endocrine and Metabolic Late Effects in Cancer Survivors

Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen
Endocrine and Metabolic Late Effects in Cancer Survivors Book PDF

Author : Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen
Publisher : Unknown
Page : 162 pages
File Size : 54,7 Mb
Release : 2021
Category : Electronic
ISBN : 3318067903

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Endocrine and Metabolic Late Effects in Cancer Survivors by Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen Pdf

This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.

Endoscopic Endonasal Transsphenoidal Surgery

Enrico de Divitiis,Paolo Cappabianca
Endoscopic Endonasal Transsphenoidal Surgery Book PDF

Author : Enrico de Divitiis,Paolo Cappabianca
Publisher : Springer Science & Business Media
Page : 203 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709160848

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Endoscopic Endonasal Transsphenoidal Surgery by Enrico de Divitiis,Paolo Cappabianca Pdf

Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions.

Growth Hormone in Adults

Anders Juul,Jens O. L. Jorgensen
Growth Hormone in Adults Book PDF

Author : Anders Juul,Jens O. L. Jorgensen
Publisher : Cambridge University Press
Page : 536 pages
File Size : 41,8 Mb
Release : 2000-04-27
Category : Medical
ISBN : 0521641888

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Growth Hormone in Adults by Anders Juul,Jens O. L. Jorgensen Pdf

This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.

Atlas of Sellar and Parasellar Lesions

Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr.
Atlas of Sellar and Parasellar Lesions Book PDF

Author : Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr.
Publisher : Springer
Page : 546 pages
File Size : 45,6 Mb
Release : 2015-10-27
Category : Medical
ISBN : 9783319228556

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Atlas of Sellar and Parasellar Lesions by Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr. Pdf

This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.

Paediatric Thyroidology

G. Szinnai
Paediatric Thyroidology Book PDF

Author : G. Szinnai
Publisher : Karger Medical and Scientific Publishers
Page : 260 pages
File Size : 40,8 Mb
Release : 2014-09-15
Category : Medical
ISBN : 9783318027211

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Paediatric Thyroidology by G. Szinnai Pdf

This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors. Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics. Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.