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Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press, USA
Page : 609 pages
File Size : 54,5 Mb
Release : 2018
Category : Medical
ISBN : 9780190862800
Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.
Author : Karthik Ramasamy,Sagar Lonial
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 49,7 Mb
Release : 2017-01-09
Category : Medical
ISBN : 9781910797334
Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care
Author : Aldo M. Roccaro,Irene M. Ghobrial
Publisher : Springer
Page : 361 pages
File Size : 43,5 Mb
Release : 2016-10-01
Category : Medical
ISBN : 9783319403205
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
Author : Edward F. McCarthy,Frank J. Frassica
Publisher : Cambridge University Press
Page : 385 pages
File Size : 54,6 Mb
Release : 2014-11-20
Category : Medical
ISBN : 9781107041233
Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.
Author : Todd M. Zimmerman,Shaji K. Kumar
Publisher : Springer
Page : 202 pages
File Size : 51,9 Mb
Release : 2016-09-17
Category : Medical
ISBN : 9781441968487
This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.
Author : David Schiff,Santosh Kesari,Patrick C. Y. Wen
Publisher : Springer Science & Business Media
Page : 636 pages
File Size : 41,9 Mb
Release : 2008-07-11
Category : Medical
ISBN : 9781597454124
Neuro-oncology has evolved substantially as a clinical and research discipline over the past few decades. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition provides clinicians from various backgrounds and levels of training with a reference to help focus the differential diagnosis, treatment strategy, and management plan for the cancer patient with neurologic symptoms and findings. The volume begins with an overview of the field of neuro-oncology and a review of the role of neuroimaging in the diagnosis of neuro-oncologic disease. Several chapters on interpretation and management of common neuro-oncologic symptoms follow. Subsequent sections contain chapters on the direct and indirect neurologic complications of cancer as well as complications of therapy. The final section focuses on the spectrum and management of neurologic disease in patients with cancer of specific organs. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition is an important new work that aims to broaden and deepen the familiarity of clinicians with the range and management of neuro-oncologic diseases in order to improve the quality of care for cancer patients.
Author : Derek Raghavan,Manmeet S. Ahluwalia,Charles D. Blanke,Jubilee Brown,Edward S. Kim,Gregory H. Reaman,Mikkael A. Sekeres
Publisher : John Wiley & Sons
Page : 1296 pages
File Size : 51,6 Mb
Release : 2017-03-03
Category : Medical
ISBN : 9781119196211
The fifth edition of the only comprehensive text dealing exclusively with rare or infrequently encountered malignancies in adults and children is an essential resource for any clinical oncologist. Encompasses all the information needed to diagnose and manage uncommon cancers, an area where advice and guidance is typically scarce Fully revised with new material and an evidence-based, teach-by-example approach Provides insight on real-world decision making in the clinical setting Edited and authored by a highly experienced and senior team of medical oncologists, radiation oncologists, and other specialists, giving a balanced and complete overview Extensively illustrated in full color throughout, including heat maps to show gene expression
Author : Morie A. Gertz,S. Vincent Rajkumar
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 42,8 Mb
Release : 2013-10-01
Category : Medical
ISBN : 9781461485209
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Author : Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos
Publisher : Springer
Page : 245 pages
File Size : 53,9 Mb
Release : 2018-02-16
Category : Medical
ISBN : 9783319255866
This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.
Author : Dan Jones
Publisher : Springer Science & Business Media
Page : 636 pages
File Size : 40,9 Mb
Release : 2010-01-24
Category : Medical
ISBN : 9781607613848
Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias. Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation. Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.
Author : John J. Kelly,Robert A. Kyle,Norman Latov
Publisher : Springer Science & Business Media
Page : 158 pages
File Size : 52,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461320654
Plasma cell dyscrasias are common causes of peripheral neuropathy. Peri pheral neuropathy may be the first manifestation of multiple myeloma, amyloidosis, or monoclonal gammopathy of undetermined significance (MGUS). Peripheral neuropathy occurs in more than one-half of patients with osteosclerotic myeloma. The hematologic disorders are such an important association with peripheral polyneuropathy that, for the last decade, we have obtained a metastatic bone survey and immunoelectrophoresis of serum and a 24-hour urine specimen on all patients older than 40 years with undiagnosed peripheral neuropathy. This textbook on polyneuropathies and plasma cell dyscrasia is welcome, because the subject is of considerable medical importance and because the authors are expert in these disorders. Kelly's studies have shown that a systematic search for monoclonal proteins in plasma and urine among patients with neuropathy of unknown cause increases diagnostic yield. Latov's studies have focused on the role of myelin associated glycoproteins (MAG) in the induction of neuropathy. Kyle, director of the Special Protein Laboratory at Mayo Clinic, brings a broad clinical and laboratory perspective and experi ence. The timing of the textbook is just right, because there is much new information which needs to be summarized.
Author : Karthik Ramasamy,Sagar Lonial
Publisher : Health Press (NM)
Page : 0 pages
File Size : 44,6 Mb
Release : 2015-08-03
Category : Multiple myeloma
ISBN : 1908541954
Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis. Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.
Author : Karthik Ramasamy,Sagar Lonial
Publisher : Unknown
Page : 152 pages
File Size : 50,9 Mb
Release : 2015-08-03
Category : Electronic
ISBN : 1910797073
Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis.Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.
Author : J. S. Malpas
Publisher : Elsevier Health Sciences
Page : 472 pages
File Size : 54,8 Mb
Release : 2004
Category : Medical
ISBN : UOM:39015058254387
This book was prompted by a renewed interest in the biology of myeloma, new concepts with regard to its clinical evolution, and options for therapy that have not been available before. Myeloma has always involved many systems and caused many problems for the clinician. It has become a focus of attention for the scientist and clinician.
Author : Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy
Publisher : Unknown
Page : 637 pages
File Size : 53,6 Mb
Release : 2013-06-04
Category : Hematology
ISBN : 0982843518
Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.
