Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias

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Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias

Karthik Ramasamy,Sagar Lonial
Fast Facts Multiple Myeloma and Plasma Cell Dyscrasias Book PDF

Author : Karthik Ramasamy,Sagar Lonial
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 45,7 Mb
Release : 2017-01-09
Category : Medical
ISBN : 9781910797334

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Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias by Karthik Ramasamy,Sagar Lonial Pdf

Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care

Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias, Lite Version

Karthik Ramasamy,Sagar Lonial
Fast Facts Multiple Myeloma and Plasma Cell Dyscrasias Lite Version Book PDF

Author : Karthik Ramasamy,Sagar Lonial
Publisher : Unknown
Page : 152 pages
File Size : 46,8 Mb
Release : 2015-08-03
Category : Electronic
ISBN : 1910797073

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Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias, Lite Version by Karthik Ramasamy,Sagar Lonial Pdf

Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis.Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.

Multiple Myeloma and Plasma Cell Dyscrasias

Karthik Ramasamy,Sagar Lonial
Multiple Myeloma and Plasma Cell Dyscrasias Book PDF

Author : Karthik Ramasamy,Sagar Lonial
Publisher : Health Press (NM)
Page : 0 pages
File Size : 48,9 Mb
Release : 2015-08-03
Category : Multiple myeloma
ISBN : 1908541954

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Multiple Myeloma and Plasma Cell Dyscrasias by Karthik Ramasamy,Sagar Lonial Pdf

Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis. Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.

Fast Facts: Myeloma

Karthik Ramasamy
Fast Facts Myeloma Book PDF

Author : Karthik Ramasamy
Publisher : Karger Medical and Scientific Publishers
Page : 30 pages
File Size : 47,6 Mb
Release : 2016-11-21
Category : Medical
ISBN : 9781910797341

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Fast Facts: Myeloma by Karthik Ramasamy Pdf

Information + Taking Control = Best Outcome is the theme running through this short, superbly illustrated workbook, which is designed to help patients equip themselves with the best information about myeloma. Starting with a simple overview of the biology of the disease, this comprehensive resource will also help patients to understand the type of myeloma that they have, the remitting-relapsing nature of the disease, and the signs and symptoms they are likely to experience. 'Fast Facts: Myeloma for Patients and their Supporters' takes patients through the initial treatment options and their side effects, what to expect if they have stem cell transplantation, and how they will be treated when their symptoms return. The final sections will help patients understand what supportive care options are available to them, and provide an insight into the latest myeloma research, which is progressing on many fronts. With FastTests to test patients' understanding of their condition throughout, and plenty of space for patients to write their own notes, this concise, easy-to-read resource will help patients get organized so that they are better equipped to ask the right questions and have more meaningful discussions with their doctors and nurses. Ultimately, it will help them make the best decisions about their care. Contents: • Information + Taking Control = Best Outcome • What is myeloma? • Who gets myeloma and why? • How is myeloma diagnosed? • What type of myeloma do I have? • What are the effects of myeloma? • What is staging and why is it done? • What initial treatment will I receive? • Stem cell transplantation • Monitoring the effects of therapy • Treatment when myeloma returns • Supportive care • Research to follow and support • Useful resources

Fast Facts: Lymphoma

Graham P. Collins,Toby A. Eyre,Eliza Hawkes
Fast Facts Lymphoma Book PDF

Author : Graham P. Collins,Toby A. Eyre,Eliza Hawkes
Publisher : Karger Medical and Scientific Publishers
Page : 188 pages
File Size : 46,7 Mb
Release : 2023-07-20
Category : Medical
ISBN : 9783318072860

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Fast Facts: Lymphoma by Graham P. Collins,Toby A. Eyre,Eliza Hawkes Pdf

Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.

Fast Facts: Heart Failure

Dariusz Korczyk,Gerry Kaye
Fast Facts Heart Failure Book PDF

Author : Dariusz Korczyk,Gerry Kaye
Publisher : Karger Medical and Scientific Publishers
Page : 154 pages
File Size : 51,9 Mb
Release : 2017-04-17
Category : Medical
ISBN : 9781910797327

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Fast Facts: Heart Failure by Dariusz Korczyk,Gerry Kaye Pdf

Effective new treatments - from drugs to surgery to devices - are revolutionizing both outcome and wellbeing in patients with heart failure. Written with the non-specialist in mind, this practical resource distills a lot of complex information into a refreshingly readable format, with clear informative diagrams and useful pull-out tables. Highlights include: • a concise discussion of the pathophysiological mechanisms that lead to heart failure • a detailed review of the causes and comorbidities of heart failure • simple advice on diagnosis and investigation • clear management principles, including healthy lifestyle choices for patients • evidence-based guidance on first- and second-line drug therapies and medical management that targets the underlying cause • a comprehensive overview of non-pharmacological treatment options, including devices and transplantation • important information on palliative care in end-stage heart failure. 'Fast Facts: Heart Failure' is the ideal resource for primary care providers, specialist nurses and cardiology trainees, and a good introduction to heart failure for all healthcare professionals who care for the elderly. Contents: • Definitions and epidemiology • Pathophysiology and clinical stages • Causes • Comorbidities • Diagnosis • General management and lifestyle considerations • Pharmacological treatment • Non-pharmacological treatment • Prognosis • Clinical trials and developments • Useful resources

Multiple Myeloma

Morie A. Gertz,S. Vincent Rajkumar
Multiple Myeloma Book PDF

Author : Morie A. Gertz,S. Vincent Rajkumar
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 44,7 Mb
Release : 2013-10-01
Category : Medical
ISBN : 9781461485209

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Multiple Myeloma by Morie A. Gertz,S. Vincent Rajkumar Pdf

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

The Saint-Chopra Guide to Inpatient Medicine

Sanjay Saint,Vineet Chopra
The Saint Chopra Guide to Inpatient Medicine Book PDF

Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press, USA
Page : 609 pages
File Size : 49,5 Mb
Release : 2018
Category : Medical
ISBN : 9780190862800

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The Saint-Chopra Guide to Inpatient Medicine by Sanjay Saint,Vineet Chopra Pdf

Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.

Plasma Cell Dyscrasias

Aldo M. Roccaro,Irene M. Ghobrial
Plasma Cell Dyscrasias Book PDF

Author : Aldo M. Roccaro,Irene M. Ghobrial
Publisher : Springer
Page : 361 pages
File Size : 42,5 Mb
Release : 2016-10-01
Category : Medical
ISBN : 9783319403205

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Plasma Cell Dyscrasias by Aldo M. Roccaro,Irene M. Ghobrial Pdf

This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.

Podocytopathy

Z.-H. Liui,J.C. He
Podocytopathy Book PDF

Author : Z.-H. Liui,J.C. He
Publisher : Karger Medical and Scientific Publishers
Page : 277 pages
File Size : 50,8 Mb
Release : 2014-05-16
Category : Medical
ISBN : 9783318026511

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Podocytopathy by Z.-H. Liui,J.C. He Pdf

The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Cancer and the Kidney

Eric P. Cohen
Cancer and the Kidney Book PDF

Author : Eric P. Cohen
Publisher : Oxford University Press, USA
Page : 382 pages
File Size : 51,6 Mb
Release : 2010-11-11
Category : Medical
ISBN : 9780199580194

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Cancer and the Kidney by Eric P. Cohen Pdf

Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.

Multiple Myeloma and Other Plasma Cell Neoplasms

Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos
Multiple Myeloma and Other Plasma Cell Neoplasms Book PDF

Author : Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos
Publisher : Springer
Page : 245 pages
File Size : 46,8 Mb
Release : 2018-02-16
Category : Medical
ISBN : 9783319255866

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Multiple Myeloma and Other Plasma Cell Neoplasms by Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos Pdf

This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.

Nuclear Oncology

H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson
Nuclear Oncology Book PDF

Author : H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson
Publisher : Springer Science & Business Media
Page : 877 pages
File Size : 45,8 Mb
Release : 2012-11-27
Category : Medical
ISBN : 9780387488943

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Nuclear Oncology by H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson Pdf

This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.

American Society of Hematology Self-Assessment Program

Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy
American Society of Hematology Self Assessment Program Book PDF

Author : Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy
Publisher : Unknown
Page : 637 pages
File Size : 41,7 Mb
Release : 2013-06-04
Category : Hematology
ISBN : 0982843518

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American Society of Hematology Self-Assessment Program by Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy Pdf

Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.

The Causes and Consequences of Chromosomal Aberrations

Ilan R. Kirsch
The Causes and Consequences of Chromosomal Aberrations Book PDF

Author : Ilan R. Kirsch
Publisher : CRC Press
Page : 556 pages
File Size : 44,5 Mb
Release : 1992-12-21
Category : Science
ISBN : 0849388937

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The Causes and Consequences of Chromosomal Aberrations by Ilan R. Kirsch Pdf

The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics.