Plasticity And Pathology

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Plasticity and Pathology

Author : David Bates,Nima Bassiri
Publisher : Fordham University Press
Page : 368 pages
File Size : 43,9 Mb
Release : 2016-01-15
Category : Science
ISBN : 9780823266166

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Plasticity and Pathology by David Bates,Nima Bassiri Pdf

With the rise of cognitive science and the revolution in neuroscience, it is now commonplace to assume that the study of a human person—a thinking, feeling, acting subject—is ultimately the study of the human brain. In both Europe and the United States, massive state-funded research is focused on mapping the brain in all its remarkable complexity. The metaphors employed are largely technological: A wiring diagram of synaptic connectivity will lead to a better understanding of human behavior and perhaps insights into the breakdown of human personhood with diseases of the brain such as Alzheimer’s. Alongside this technologized discourse of the brain as locus of human subjectivity we find another perspective, one that emphasizes its essential plasticity—in both the developmental sense and as a response to traumas such as strokes, tumors, or gunshot wounds. This collection of essays brings together a diverse range of scholars to investigate how the “neural subject” of the twenty-first century came to be. Taking approaches both historical and theoretical, they probe the possibilities and limits of neuroscientific understandings of human experience. Topics include landmark studies in the history of neuroscience, the relationship between neural and technological “pathologies,” and analyses of contemporary concepts of plasticity and pathology in cognitive neuroscience. Central to the volume is a critical examination of the relationship between pathology and plasticity. Because pathology is often the occasion for neural reorganization and adaptation, it exists not in opposition to the brain’s “normal” operation but instead as something intimately connected to our ways of being and understanding.

Plasticity and Pathology

Author : David William Bates,Nima Bassiri
Publisher : Unknown
Page : 351 pages
File Size : 41,5 Mb
Release : 2016
Category : Medical
ISBN : 0823266133

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Plasticity and Pathology by David William Bates,Nima Bassiri Pdf

The essays collected here were presented at the workshop Plasticity and Pathology: History and Theory of Neural Subjects at the Doreen B. Townsend Center for the Humanities at the University of California, Berkeley.

Disorders of Synaptic Plasticity and Schizophrenia

Author : Anonim
Publisher : Academic Press
Page : 559 pages
File Size : 44,7 Mb
Release : 2004-05-10
Category : Medical
ISBN : 9780080548623

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Disorders of Synaptic Plasticity and Schizophrenia by Anonim Pdf

Schizophrenia is a severe brain disorder that affects 1% of the population. Its cause is due to the interaction of a number of abnormal genes with environmental factors. This book summarizes new advances schizophrenia research that focus on the field of neural and synaptic plasticity. Synapses in the brain in schizophrenia show a wide range of disorders, both structural and functional. This volume covers the most active and promising of these new developments, and opens up new avenues for the treatment of schizophrenia. * Addresses new areas of research in neurotransmitters, receptors, vitamin transport, metabolism, and signaling. * Reviews the growing field of synaptic plasticity research* Provides links with other diseases of the Central Nervous System (CNS)

Hormones and Brain Plasticity

Author : Luis Miguel Garcia-Segura
Publisher : Oxford University Press
Page : 505 pages
File Size : 40,6 Mb
Release : 2009-05-05
Category : Medical
ISBN : 9780195326611

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Hormones and Brain Plasticity by Luis Miguel Garcia-Segura Pdf

Proposing that hormones modulate metaplasticity in the brain, the author covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism.--[Source inconnue].

Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic

Author : Jordan Grafman
Publisher : Springer Science & Business Media
Page : 191 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642598975

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Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic by Jordan Grafman Pdf

Over the last twenty years there has been an explosive growth in our understanding of the molecular, cellular, and anatomical changes that occur in the days and weeks following brain injury. It is now clear that training and exposure to certain environments can modify and shape neuronal plasticity in lower animals and humans. In humans, in particular, there are new ways of charting neuronal plasticity at the ensemble or regional level using functional neuroimaging techniques such as positron emission tomography and functional magnetic resonance imaging. Thus, the time seems right for transporting the laboratory results to the clinic so that experimental findings can be tested in the "field". This volume provides some impetus to moving the field of cognitive neuroscience a little further in its efforts to improve the lives of patients who have suffered a debilitating brain injury.

Receptor Dynamics in Neural Development

Author : Christopher Ari Shaw
Publisher : CRC Press
Page : 370 pages
File Size : 55,8 Mb
Release : 1996-02-13
Category : Science
ISBN : 0849378176

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Receptor Dynamics in Neural Development by Christopher Ari Shaw Pdf

This book provides a comprehensive review of what receptors do in the nervous system, how they do it, the mechanisms by which receptor function is regulated, and the consequences of normal and abnormal receptor function. It contains a series of interrelated chapters describing key neurotransmitter receptors, protein kinases, and protein phosphatases, and details their expression and composition in the development of the central nervous system (CNS).

Plasticity in the Somatosensory System of Developing and Mature Mammals — The Effects of Injury to the Central and Peripheral Nervous System

Author : Peter J. Snow,Peter Wilson
Publisher : Springer Science & Business Media
Page : 497 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642757013

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Plasticity in the Somatosensory System of Developing and Mature Mammals — The Effects of Injury to the Central and Peripheral Nervous System by Peter J. Snow,Peter Wilson Pdf

Rarely have the many mechanisms that might underlie neural plasticity been examined as explicitly as they are in this broad, lavishly illustrated treatment of plasticity in the somatosensory system. The reader is provided with state-of-the-art knowledge of connections at all levels of the somatosensory system. The authors examine the propensity for changes of connectivity in both the mature and developing mammal and make clear proposals regarding the mechanisms underlying these changes. Their functional significance to relevant psychophysical and neurological observations is also discussed.

The Rewiring Brain

Author : Arjen van Ooyen,Markus Butz-Ostendorf
Publisher : Academic Press
Page : 592 pages
File Size : 54,5 Mb
Release : 2017-06-23
Category : Science
ISBN : 9780128038727

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The Rewiring Brain by Arjen van Ooyen,Markus Butz-Ostendorf Pdf

The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage

Catastrophes

Author : Nitzan Lebovic,Andreas Killen
Publisher : Walter de Gruyter GmbH & Co KG
Page : 207 pages
File Size : 53,5 Mb
Release : 2014-07-28
Category : History
ISBN : 9783110373776

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Catastrophes by Nitzan Lebovic,Andreas Killen Pdf

Catastrophic scenarios dominate our contemporary mindset. Catastrophic events and predictions have spurred new interest in re-examining the history of earlier disasters and the social and conceptual resources they have mobilized. The essays gathered in this volume reconsider the history and theory of different catastrophes and their aftermath. The emphasis is on the need to distance this process of reconsideration from previous teleological representations of catastrophes as an endpoint, and to begin considering their "operative" aspects, which unmask the nature of social and political structures. Among the essays in this volume are analyses, by leading scholars in their respective fields, concerning the role of catastrophes in theology, in the history of industrial accidents, in theory of history, in the history of law, in "catastrophe films", in the history of cybernetics, in post-Holocaust discussions of reparations, and in climate change.

Tau Protein: Mechanisms from Health to Degeneration

Author : Isabel Lastres-Becker,Javier Egea
Publisher : Frontiers Media SA
Page : 299 pages
File Size : 52,5 Mb
Release : 2022-01-03
Category : Science
ISBN : 9782889719235

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Tau Protein: Mechanisms from Health to Degeneration by Isabel Lastres-Becker,Javier Egea Pdf

The Elements of Surgical Pathology

Author : James Grant Gilchrist
Publisher : Unknown
Page : 370 pages
File Size : 51,7 Mb
Release : 1895
Category : Pathology, Surgical
ISBN : UOM:39015020061597

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The Elements of Surgical Pathology by James Grant Gilchrist Pdf

Molecular Pharmacology and Pathology of Strokes

Author : Joen-Rong Sheu,Howard Prentice
Publisher : MDPI
Page : 153 pages
File Size : 55,5 Mb
Release : 2019-02-11
Category : Biochemistry
ISBN : 9783038975410

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Molecular Pharmacology and Pathology of Strokes by Joen-Rong Sheu,Howard Prentice Pdf

This book is a printed edition of the Special Issue "Molecular Pharmacology and Pathology of Strokes" that was published in IJMS

Cell-Cycle Mechanisms and Neuronal Cell Death

Author : Agata Copani,Ferdinando Nicoletti
Publisher : Springer Science & Business Media
Page : 110 pages
File Size : 40,9 Mb
Release : 2007-03-06
Category : Medical
ISBN : 9780387293905

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Cell-Cycle Mechanisms and Neuronal Cell Death by Agata Copani,Ferdinando Nicoletti Pdf

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer’s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.