Pocket Guide Pharmacokinetics Made Easy

Author : Donald J. Birkett
Publisher : McGraw-Hill Education Australia
Page : 136 pages
File Size : 49,5 Mb
Release : 2009-12-18
Category : Medical
ISBN : 9781743765166

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Pocket Guide by Donald J. Birkett Pdf

Presents a complex topic in a simple, easy-to-understand way Pocket Guide: Pharmacokinetics Made Easy is the latest update of the popular Pharmacokinetics Made Easy. It is suitable for a wide audience including medical practitioners, health professionals, and students. The individual chapters were initially published as a series of articles in Australian Prescriber to assist practitioners in drug dosing and therapy. The physiological approach herein adopted addresses clinical issues in drug therapy and makes them directly applicable to practice situations. Key Selling Features: - Self-assessment questions in each chapter - Glossary of symbols - Use of equations to explain physiological factors underlying important pharmacokinetics processes - Endorsed and co-published with Australian Prescriber - List of key points summarizing the content to improve accessibility and understanding

Author : Donald Birkett
Publisher : McGraw-Hill Education / Australia
Page : 0 pages
File Size : 55,5 Mb
Release : 2009-12-18
Category : Medical
ISBN : 0070285276

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Pocket Guide: Pharmacokinetics Made Easy by Donald Birkett Pdf

This text covers the principles and concepts of clinical pharmacokinetics. It explains the concepts in an approach to drug dosing and therapy.

Author : Donald John Birkett
Publisher : Unknown
Page : 120 pages
File Size : 46,7 Mb
Release : 2010
Category : Electronic
ISBN : OCLC:1123956360

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Pharmacokinetics Made Easy by Donald John Birkett Pdf

Author : Donald Birkett
Publisher : Unknown
Page : 137 pages
File Size : 44,9 Mb
Release : 2010
Category : Electronic
ISBN : 1743075723

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Pocket Guide by Donald Birkett Pdf

Pharmacokinetics Made Easy presents a complex subject in a simple, easy-to-understand manner. It is suitable for a wide audience including medical practitioners, health professionals and students. The individual chapters were initially published as a series of articles in Australian Prescriber to assist practitioners in drug dosing and therapy.

Author : Johan Gabrielsson,Daniel Weiner
Publisher : CRC Press
Page : 926 pages
File Size : 52,9 Mb
Release : 2001-11-30
Category : Medical
ISBN : 9186274929

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Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition by Johan Gabrielsson,Daniel Weiner Pdf

This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.

Author : Biswajit Mukherjee
Publisher : Springer Nature
Page : 354 pages
File Size : 46,5 Mb
Release : 2022-03-17
Category : Medical
ISBN : 9789811689505

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Pharmacokinetics: Basics to Applications by Biswajit Mukherjee Pdf

This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.

Author : Thomas N. Tozer,Malcolm Rowland
Publisher : Lippincott Williams & Wilkins
Page : 342 pages
File Size : 48,6 Mb
Release : 2006
Category : Medical
ISBN : 0781751497

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Introduction to Pharmacokinetics and Pharmacodynamics by Thomas N. Tozer,Malcolm Rowland Pdf

This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Author : G. M. Woerlee
Publisher : Troubador Publishing Ltd
Page : 153 pages
File Size : 49,7 Mb
Release : 2005
Category : Drugs
ISBN : 9781905237166

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Gerry's Real World Guide to Pharmacokinetics & Other Things by G. M. Woerlee Pdf

Written by an anaesthetist with years of experience, this serious textbook uses a blunt and 'tongue in cheek' approach.

Author : Joseph T. DiPiro
Publisher : ASHP
Page : 265 pages
File Size : 55,7 Mb
Release : 2010
Category : Medical
ISBN : 9781585282418

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Concepts in Clinical Pharmacokinetics by Joseph T. DiPiro Pdf

Short Description: This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.

Author : John E. Murphy
Publisher : Unknown
Page : 0 pages
File Size : 42,9 Mb
Release : 2017
Category : Pharmacokinetics
ISBN : 1585285366

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Clinical Pharmacokinetics by John E. Murphy Pdf

In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.

Author : Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 50,6 Mb
Release : 2013-11-23
Category : Medical
ISBN : 9780387756134

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics by Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton Pdf

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Author : John G. Wagner
Publisher : Routledge
Page : 334 pages
File Size : 46,6 Mb
Release : 2018-12-19
Category : Medical
ISBN : 9781351425124

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Pharmacokinetics for the Pharmaceutical Scientist by John G. Wagner Pdf

Major presentation of pharmacokinetics by a leading international expert. Methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug.

Author : Sara E. Rosenbaum
Publisher : John Wiley & Sons
Page : 576 pages
File Size : 55,5 Mb
Release : 2016-11-22
Category : Medical
ISBN : 9781119143161

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Basic Pharmacokinetics and Pharmacodynamics by Sara E. Rosenbaum Pdf

Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)

Author : James M. Ritter,Rod J. Flower,Graeme Henderson,Yoon Kong Loke,David MacEwan,Emma Robinson,James Fullerton
Publisher : Elsevier Health Sciences
Page : 1001 pages
File Size : 52,9 Mb
Release : 2023-05-13
Category : Medical
ISBN : 9780323873987

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Rang & Dale's Pharmacology E-Book by James M. Ritter,Rod J. Flower,Graeme Henderson,Yoon Kong Loke,David MacEwan,Emma Robinson,James Fullerton Pdf

Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines Clear figures to aid understanding, including data figures as well as mechanistic diagrams, Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts Emphasis on therapeutic drugs to help apply theory to practice Over 150 questions and 12 clinical cases to test your knowledge New chapters on drugs and the eye and the pharmacological management of headache Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. A completely revised and updated chapter on lifestyle drugs Recent advances in oxygen sensing and response to reduced oxygen tension Expanded chapters on dementia and analgesic drugs

Author : Peter L. Bonate
Publisher : Springer Science & Business Media
Page : 634 pages
File Size : 49,8 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9781441994851

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Pharmacokinetic-Pharmacodynamic Modeling and Simulation by Peter L. Bonate Pdf

This is a second edition to the original published by Springer in 2006. The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models. Since the first edition was published the field has grown considerably in terms of maturity and technicality. The second edition of the book therefore considerably expands with the addition of three new chapters relating to Bayesian models, Generalized linear and nonlinear mixed effects models, and Principles of simulation. In addition, many of the other chapters have been expanded and updated.