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Author : Shin-ichi Yusa,Pratap Bahadur,Hideki Matsuoka,Takahiro Sato
Publisher : MDPI
Page : 229 pages
File Size : 46,5 Mb
Release : 2018-04-20
Category : Electronic book
ISBN : 9783038428077
This book is a printed edition of the Special Issue "Polymer Micelles" that was published in Polymers
Author : Prashant Kesharwani,Khaled Greish
Publisher : Woodhead Publishing
Page : 716 pages
File Size : 41,9 Mb
Release : 2022-08-18
Category : Technology & Engineering
ISBN : 9780323886291
Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles. Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles – such as mucosal and transdermal – and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation. Explores how polymeric micelles can be utilized in a range of different drug delivery approaches, from traditional oral delivery to ocular and dermal delivery Describes the various polymer types used in the synthesis and characterization of polymeric micelles Covers recent advances in polymeric micelles, such as drug co-delivery, triblock polymeric micelles, delivery of genetic materials, and more
Author : Sachin Kumar Singh,Monica Gulati,Srinivas Mutalik,Muralikrishnan Dhanasekaran,Kamal Dua
Publisher : Springer Nature
Page : 302 pages
File Size : 53,5 Mb
Release : 2023-04-08
Category : Medical
ISBN : 9789819903610
This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
Author : V. P. Torchilin
Publisher : Imperial College Press
Page : 758 pages
File Size : 54,7 Mb
Release : 2006
Category : Technology & Engineering
ISBN : 9781860949074
Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."
Author : Shigeru Kunugi,Tetsuji Yamaoka
Publisher : Springer Science & Business Media
Page : 290 pages
File Size : 48,8 Mb
Release : 2012-02-02
Category : Technology & Engineering
ISBN : 9783642278556
Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery, by Ernst Wagner Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine, by Takami Akagi, Masanori Baba and Mitsuru Akashi Biodegradable Polymeric Assemblies for Biomedical Materials, by Yuichi Ohya, Akihiro Takahashi and Koji Nagahama PEGylation Technology in Nanomedicine, by Yutaka Ikeda and Yukio Nagasaki Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions, by Kazuhiko Ishihara, Yan Xu and Tomohiro Konno Design of Biointerfaces for Regenerative Medicine, by Yusuke Arima, Koichi Kato, Yuji Teramura and Hiroo Iwata Advances in Tissue Engineering Approaches to Treatment of Intervertebral Disc Degeneration: Cells and Polymeric Scaffolds for Nucleus Pulposus Regeneration, by Jeremy J. Mercuri and Dan T. Simionescu Functionalized Biocompatible Nanoparticles for Site-Specific Imaging and Therapeutics, by Ranu K. Dutta, Prashant K. Sharma, Hisatoshi Kobayashi and Avinash C. Pandey
Author : Shin-ichi Yusa,Pratap Bahadur,Hideki Matsuoka,Takahiro Sato
Publisher : Unknown
Page : 128 pages
File Size : 54,5 Mb
Release : 2018
Category : Electronic
ISBN : 3038428086
Author : Raoul Zana,Eric W. Kaler
Publisher : CRC Press
Page : 639 pages
File Size : 47,9 Mb
Release : 2007-05-30
Category : Science
ISBN : 9781000654288
The co-evolution of a strong theoretical framework alongside application of a range of sophisticated experimental tools engendered rapid advancement in the study ofgiant micelles. Beginning with Anacker and Debye's 1951 experimental study of elongated micelles by light scattering and their subsequent theoretical inference that the thermodynamic
Author : Mansoor M. Amiji
Publisher : CRC Press
Page : 840 pages
File Size : 52,9 Mb
Release : 2006-12-19
Category : Medical
ISBN : 9781420006636
While simultaneous breakthroughs occurring in molecular biology and nanoscience/technology will ultimately revolutionize all of medicine, it is with our efforts to prevent, diagnose, and treat cancer that many of the most dramatic advances will occur. In support of this potential, the U.S. National Cancer Institute (NCI) established the Alliance fo
Author : Jerry L. Atwood,Jonathan W. Steed
Publisher : John Wiley & Sons
Page : 380 pages
File Size : 49,5 Mb
Release : 2008-03-31
Category : Science
ISBN : 3527318364
Filling the need for a volume on the organic side of nanotechnology, this comprehensive overview covers all major nanostructured materials in one handy volume. Alongside metal organic frameworks, this monograph also treats other modern aspects, such as rotaxanes, catenanes, nanoporosity and catalysis. Detailed attention is paid to the chemistry, physics and materials science throughout, making this a definite must for all chemists.
Author : Paul Dubin
Publisher : Springer Science & Business Media
Page : 451 pages
File Size : 46,5 Mb
Release : 2013-03-09
Category : Technology & Engineering
ISBN : 9781461321231
In the first half of this century, great strides were made in under standing the behavior of polymers in dilute solutions or in the solid state. Concentrated solutions, on the other hand, were commonly regarded as mainly of interest to practitioners, being too complex for the rigorous application of statistical theory. Given the preoccupation with the isolated polymer molecule and the attendant focus on the state of infinite dilution, it is not surprising that aggregation, and inter-polymer associ ation in general, was the bugaboo of experimentalists. These attitudes have changed remarkably over the last few decades. The application of sealing theory to polymer solutions has stimulated investigation of the semi-dilute state, and the region between infinite dilution and swollen gel is no longer perceived as terra incognita. New techniques, such as dynamic light scattering, have proven to be of much value in such investigations. At the same time, it has become clear that consideration of strong inter- and intra-polymer forces, superimposed on the familiar description of the statistical chain, is prerequisite to the application of polymer science to numerous systems of interest. Para mount among these, of course, are biopolymers, their complexes and assemblies. The isolated random coil must be viewed as tl rarity in nature.
Author : Tsuneya Ikezu,Howard E. Gendelman
Publisher : Springer Science & Business Media
Page : 828 pages
File Size : 43,6 Mb
Release : 2008-03-21
Category : Medical
ISBN : 9780387725734
Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer’s and Parkinson’s as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.
Author : Nicholas D. Spencer,John H. Moore
Publisher : Taylor & Francis
Page : 734 pages
File Size : 47,9 Mb
Release : 2001
Category : Science
ISBN : 0750308001
Author : Ann Van Eeckhaut,Yvette Michotte
Publisher : CRC Press
Page : 543 pages
File Size : 55,9 Mb
Release : 2009-11-11
Category : Science
ISBN : 1420069349
Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary Electrophoresis Since the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist’s toolkit. With contributions from international experts, Chiral Separations by Capillary Electrophoresis provides a general overview of the principles of chiral separation by capillary electrophoresis and the different chiral selectors available. The book discusses the most important as well as several new chiral selectors used in capillary electrophoresis. It reviews recent pharmaceutical and biomedical applications and explores novel techniques, such as capillary electrophoresis coupled to mass spectrometry and microchip technology. The book also examines the quantitative aspects of capillary electrophoresis, the possibilities of capillary electrochromatography, and the various chiral columns available. Capillary electrophoresis has proven to be an effective tool for chiral separation. This book explains how this technique can be used in the separation of molecules, offering insight into both existing and emerging applications.
Author : Neeraj Mishra,Vikas Pandey
Publisher : Springer Nature
Page : 440 pages
File Size : 44,7 Mb
Release : 2023-11-29
Category : Medical
ISBN : 9789819969173
This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
Author : Patricia I. Dolez
Publisher : Elsevier
Page : 736 pages
File Size : 54,6 Mb
Release : 2015-05-26
Category : Technology & Engineering
ISBN : 9780444627452
Nanoengineering: Global Approaches to Health and Safety Issues provides a global vision on the impact of engineered nanomaterials both for the consumer/general public and in occupational settings. The book also presents a hint on what can be expected for the future from nanomaterials and their effects on our lives, both at home and at work. In addition, users will find valuable information on nanomaterials' irreplaceable value and their risks for health, safety, and environmental issues. Case studies illustrate key points and provide information on important processes. Provides a global vision on the different aspects related to nanosafety and a synthesis of the information available Gives all the information required for precision decision-making in a single book, offering both general public and occupational aspects Contains separate chapters on each subject written by world-renowned contributors Presents a complete vision of the problem, with perspectives on global approaches Includes case studies that illustrate important processes