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Author : Colin R. Blass
Publisher : iSmithers Rapra Publishing
Page : 112 pages
File Size : 43,8 Mb
Release : 1999
Category : Technology & Engineering
ISBN : 1859571824
Author : Zheng Zhang,Ophir Ortiz,Ritu Goyal,Joachim Kohn
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 43,9 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076750
The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.
Author : Vinny R. Sastri
Publisher : Elsevier
Page : 289 pages
File Size : 43,7 Mb
Release : 2010-03-05
Category : Technology & Engineering
ISBN : 9780815520283
No book has been published that gives a detailed description of all the types of plastic materials used in medical devices, the unique requirements that the materials need to comply with and the ways standard plastics can be modified to meet such needs. This book will start with an introduction to medical devices, their classification and some of the regulations (both US and global) that affect their design, production and sale. A couple of chapters will focus on all the requirements that plastics need to meet for medical device applications. The subsequent chapters describe the various types of plastic materials, their properties profiles, the advantages and disadvantages for medical device applications, the techniques by which their properties can be enhanced, and real-world examples of their use. Comparative tables will allow readers to find the right classes of materials suitable for their applications or new product development needs.
Author : Vinny R. Sastri
Publisher : William Andrew
Page : 324 pages
File Size : 46,7 Mb
Release : 2013-11-27
Category : Technology & Engineering
ISBN : 9780323265638
Plastics in Medical Devices is a comprehensive overview of the main types of plastics used in medical device applications. It focuses on the applications and properties that are most important in medical device design, such as chemical resistance, sterilization capability and biocompatibility. The roles of additives, stabilizers, and fillers as well as the synthesis and production of polymers are covered and backed up with a wealth of data tables. Since the first edition the rate of advancement of materials technology has been constantly increasing. In the new edition Dr. Sastri not only provides a thorough update of the first edition chapters with new information regarding new plastic materials, applications and new requirements, but also adds two chapters – one on market and regulatory aspects and supplier controls, and one on process validation. Both chapters meet an urgent need in the industry and make the book an all-encompassing reference not found anywhere else. Comprehensive coverage of uses of polymers for medical devices Unique coverage of medical device regulatory aspects, supplier control and process validation Invaluable guide for engineers, scientists and managers involved in the development and marketing of medical devices and materials for use in medical devices
Author : B.J. Lambert,F.-W. Tang,W. J. Rogers
Publisher : iSmithers Rapra Publishing
Page : 156 pages
File Size : 43,9 Mb
Release : 2001
Category : Medical
ISBN : 1859572596
The use of polymers in medical devices is growing at a steady rate. These materials are generally relatively cheap and versatile, qualities required in many bulk applications. In more specialised medical devices, polymeric components have been developed to meet challenging property and performance requirements. This review describes the process of developing polymeric products for medical applications from design requirements through to specific examples of medical devices and packaging. An additional indexed section containing several hundred abstracts from the Rapra Polymer Library database gives useful references for further reading.
Author : Colin R. Blass
Publisher : iSmithers Rapra Publishing
Page : 156 pages
File Size : 49,6 Mb
Release : 2001
Category : Medical
ISBN : 1859572588
Poly(vinyl chloride) (PVC) is the most widely used polymer in today's healthcare market. It is still the polymer of choice for single use presterilised medical devices after more than 50 years of service and it continues to dominate in cost-performance terms. This book will prove to be a mine of useful and practical information for healthcare professionals, medical device manufacturers and medical polymer producers.
Author : Kayvon Modjarrad,Sina Ebnesajjad
Publisher : Elsevier
Page : 368 pages
File Size : 51,6 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780323221696
While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. Gathers discussions of a large number of applications of polymers in medicine in one place Provides an insight into both the legal and clinical implications of device design Relevant to industry, academic and medical professionals Presents the latest developments in the field, including medical devices on a nano-scale
Author : André Colas,Jim Curtis
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 45,8 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076699
Silicone materials have been widely used in medicine for over 60 years. Available in a variety of material types, they have unique chemical and physical properties that manifest in excellent biocompatibility and biodurability for many applications. Silicone elastomers have remarkably low glass-transition temperatures and maintain their flexibility over a wide temperature range, enabling them to withstand conditions from cold storage to steam autoclaving. They have high permeability to gases and many drugs, advantageous respectively in wound care or in transdermal drug delivery. They have low surface tension and remarkable chemical stability, enabling biocompatibility and biodurability in many long-term implant applications.
Author : Syed Ali Ashter
Publisher : William Andrew
Page : 306 pages
File Size : 51,5 Mb
Release : 2022-03-09
Category : Technology & Engineering
ISBN : 9780128217382
Applications of Polymers and Plastics in Medical Devices: Design, Manufacture, and Performance is a comprehensive guide to plastic materials for medical devices, covering fundamentals, materials, applications and regulatory requirements. Sections cover the role of plastics in medical devices, socioeconomic factors, the classification of medical devices. The performance of, medical grades and suppliers of polymer materials, which are categorized by performance level are also explored, along with manufacturing processes for device components, including extrusion, casting, injection molding and assembly processes. The book then covers applications in detail, examining each device and the role that polymers and plastics play in its construction and function. This is an essential resource for engineers, R&D, and other professionals working on plastics for medical devices and those in the plastics industry, medical device manufacturing, pharmaceuticals, packaging and biotechnology. In an academic setting, this book is of interest to researchers and advanced students in medical plastics, plastics engineering, polymer science, mechanical engineering, chemical engineering, biomedical engineering and materials science. Offers systematic coverage of the major classes of polymers used in medical devices, including properties, characteristics, performance, medical grades and suppliers Reviews regulatory requirements of the FDA and other global agencies, as well as considering quality control and socioeconomic factors Includes the latest advances in plastics for medical devices, such as novel applications, use of bio-based polymers, and processing of reusable medical devices
Author : Len Czuba
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 50,8 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076644
This chapter will present a look at the medical device market with a particular focus on the materials of construction of devices and what we can expect in new products looking ahead. A deeper look at some other trends that have an effect on the direction of the medical device industry will be done. Finally, consideration will be given to a number of global factors that can have dramatic effects on our industry.
Author : Richard J. LaPorte
Publisher : Routledge
Page : 198 pages
File Size : 42,5 Mb
Release : 2017-11-01
Category : Technology & Engineering
ISBN : 9781351439558
This new text provides a practical guide to hydrophilic polymer coatings technology for applications in a wide range of medical materials and devices. It concisely provides both the scientific basics of this class of polymers and the up-to-date information needed for product development and evaluation, processing, manufacturing, and regulatory compliance. More than fifty schematics illustrate materials, processes, and equipment. The entire presentation is oriented to the practical needs of personnel involved in product development and evaluation, process engineering, and manufacturing management.
Author : Laurence W. McKeen
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 52,9 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076651
Medical devices range from simple devices, to test equipment, to implants. Plastics are used more and more in these devices, for weight, cost, and performance purposes. Examples of medical devices include surgical instruments, catheters, coronary stents, pacemakers, magnetic resonance imaging (MRI) machines, X-ray machines, prosthetic limbs, artificial hips/knees, surgical gloves, and bandages.
Author : Wei He,Roberto Benson
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 49,8 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076668
Biomaterials are an indispensable element in improving human health and quality of life. Applications of biomaterials include diagnostics (gene arrays and biosensors), medical supplies (blood bags and surgical tools), therapeutic treatments (medical implants and devices), and emerging regenerative medicine (tissue-engineered skin and cartilage). Polymers, being organic, offer a versatility that is unmatched by metals and ceramics. The wide spectrum of physical, mechanical, and chemical properties provided by polymers has fueled the extensive research, development, and applications of polymeric biomaterials. The significance of polymers as biomaterials is reflected in the market size of medical polymers, estimated to be approximately $1 billion. Many of these polymers were initially developed as plastics, elastomers, and fibers for nonmedical industrial applications, but were later developed as biomedical-specific materials. With rapid growth in modern biology and interdisciplinary collaborative efforts, polymeric biomaterials are being fashioned into bioactive and biomimetic materials, with excellent biocompatibility.
Author : NIIR Board of Consultants and Engineers
Publisher : ASIA PACIFIC BUSINESS PRESS Inc.
Page : 323 pages
File Size : 45,6 Mb
Release : 2006-10-01
Category : Business & Economics
ISBN : 9788178330006
Plastics currently form one of the most important components of the medical industry. Medical device designers and engineers increasingly prefer plastics to conventional packaging materials such as metals owing to superior flexibility offered by plastics in fabrication process. Advancements in sterilization techniques shift towards disposable devices, development of enhanced plastic materials, and technological innovations are factors driving the overall market growth and expansion. The development of novel materials such as biocompatible polymers for use in medical implants will furthermore provide the required impetus for the global medical plastics market. Every day, plastics are involved in critical surgeries, life saving efforts, and routine medical procedures. Plastic materials can be sterilized hundreds of times without degradation. Lightweight plastics are used to form replacement joints, non surgical supports, and therapy equipment. Clear plastics provide visibility for transfusions, surgeries, and diagnostic equipment of all kinds and plastics can be machined, molded, or formed into almost any shape imaginable. The use of plastics in health care field encompasses several distinct markets. Plastic is used on a large scale as medical devices like disposable syringes, optical and dental products, heart valves, contact lenses and many more medical products. This way plastic has very importance in making medical devices. The medical plastics industry is set to expand rapidly over the next decade taking up increasing proportions of GDP, as countries provide healthcare to an ageing population, access to medicine expands in developing regions and new technology is developed. This book basically deals with significance of packaging for pharmaceuticals & medical industry, tablets & capsules liquids, creams and ointments, OPVC, OPP and oriented and non oriented pet containers, blister trays for ampoules, cartridge tubes etc., shrink packaging and stretch wrapping, conducting health based risk assessments of medical materials, performance properties of metallocene polyethylene, EVA, and flexible PVC films, polyurethane thin film welding for medical device applications, polyurethane film as an alternative to PVC and latex, opportunities for PVC replacement in medical solution containers, thermoplastic silicone urethane copolymers : a new class of biomedical elastomers, selecting materials for medical products : from PVC to metallocene polyolefins, injection molding engineering plastics, assessing the performance and suitability of parylene coating etc. The present book contains the important information of plastics in medical field and their uses in various ways. This is very useful book for entrepreneurs, researchers, technocrats and technical institutions. 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Author : Anonim
Publisher : iSmithers Rapra Publishing
Page : 270 pages
File Size : 51,7 Mb
Release : 2004
Category : Medical
ISBN : 1859574483
The fourth international conference focusing on polymers used in the medical industry. The use of polymers in medical technology continues to grow and provides major business opportunities for companies who service the medical industry. Medical Polymers 2004 brought together speakers and delegates from the whole medical device supply chain to identify and address the challenges facing our industry. The conference proceedings will appeal to anyone directly involved or associated with the medical device industry. They will be of particular value for businesses involved with design and manufacturing, raw material supply, machine and equipment supply, processing and moulding. The papers presented provide an excellent overview of the current state and future potential of polymers used in the medical industry.