Precision Medicine In Cardiovascular Disease Prevention
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Precision Medicine in Cardiovascular Disease Prevention by Seth S. Martin Pdf
This book contains the current knowledge and potential future developments of precision medicine techniques including artificial intelligence, big data, mobile health, digital health and genetic medicine in the prevention of cardiovascular disease. It reviews the presently used advanced precision medicine techniques and fundamental principles that continue to act as guiding forces for many medical professionals in applying precision and preventative medical techniques in their day-to-day practices. Precision Medicine in Cardiovascular Disease Prevention describes current knowledge and potential future developments in this rapidly expanding field. It therefore provides a valuable resource for all practicing and trainee cardiologists looking to develop their knowledge and integrate precision medicine techniques into their practices.
Personalized and Precision Integrative Cardiovascular Medicine by Mark Houston Pdf
Encompassing functional cardiology, integrative medicine, and metabolic medicine/cardiology, this unique reference offers an up-to-date, expert approach to heart health wellness and treating the diseased heart and blood vessels. It provides today’s practitioners with insight into various treatment options and alternatives to pharmaceutical care and surgery, incorporating new scientific information on metabolic and integrative cardiovascular medicine from peer-reviewed articles, evidence-based medicine, and human clinical research as a foundation for practical clinical information.
Author : Peter L. M. Kerkhof,Virginia M. Miller Publisher : Springer Page : 725 pages File Size : 42,9 Mb Release : 2018-07-26 Category : Medical ISBN : 9783319779324
Sex-Specific Analysis of Cardiovascular Function by Peter L. M. Kerkhof,Virginia M. Miller Pdf
This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.
Author : Roger Blumenthal,JoAnne Foody,Nathan D. Wong Publisher : Elsevier Health Sciences Page : 632 pages File Size : 53,7 Mb Release : 2011-02-25 Category : Medical ISBN : 9781437737851
Preventive Cardiology: A Companion to Braunwald's Heart Disease E-Book by Roger Blumenthal,JoAnne Foody,Nathan D. Wong Pdf
Endorsed by the American Society for Preventive Cardiology! Preventive Cardiology - a new Companion to Braunwald’s Heart Disease - addresses the prevention and risk stratification of cardiovascular disease so that you can delay the onset of disease and moderate the effects and complications. Drs. Roger Blumenthal, JoAnne Foody, and Nathan Wong discuss the full range of relevant considerations, including the epidemiology of heart disease, risk assessment, risk factors, multiple risk factor-based prevention strategies, and developments in genetics and personalized medicine. This authoritative reference gives you the clinically relevant information you need for the effective prevention of cardiovascular disease. Recognize the factors for prevention and risk stratification around cardiovascular disease and effectively delay the onset of disease and moderate the effects and complications, even for individual who are genetically predisposed. Effectively navigate full range of considerations in prevention from epidemiology of heart disease, biology of atherosclerosis and myocardial infraction, risk assessment—established risk factors and emerging risk factors, multiple risk factor-based prevention strategies, and future directions—through genetics, personalized medicine, and much more. Tap into the expertise of prominent leaders in cardiovascular disease prevention with guidance from Drs. Roger Blumenthal—longtime director of the Framingham Heart Study—JoAnne Foody, and Nathan Wong. Gain a deeper understanding of the pathogenesis of disease and the rationale for management through discussions of basic science. Apply current clinical practice guidelines to ensure optimal outcomes in both primary and secondary prevention.
Prevention of Cardiovascular Disease: A Continuum, An Issue of Cardiology Clinics - E-Book by Prakash C. Deedwania Pdf
With the numerous advances that have been made in treatment of heart disease over the past 20 years, physicians are now emphasizing more than ever the prevention of heart disease. This issue provides cardiologists with practical state-of-the-art information on prevention that can be be easily applied to their patients. Topics covered include diabetes, lipid-lowering therapy, RAAS blockade, emerging therapies for atherosclerosis prevention, and heart disease in women.
Integrative Cardiovascular Chinese Medicine by Anika Niambi Al-Shura Pdf
Combining the research and study of integrative Chinese and Western Medicine, Integrative Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners. This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research. Integrates Western and Chinese medicine for a realistic scope of cardiology treatment Establishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology "Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical use Offers a reference section that lists the latest in published studies Presents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents
Big Data in Cardiology. Predicting, Preventing and Managing Diseases by Bikal Dhungel Pdf
Master's Thesis from the year 2020 in the subject Health Sciences - Health Logistics, grade: 1,7, Linnaeus University (School of Informatics), course: Information Systems, language: English, abstract: This study was conducted to analyze this process closer focusing on a case of Cardiology. Conducting a comprehensive literature review and qualitative expert interviews, the impact of big data in the field of Cardiology was explored. The result of the study shows that big data can play a positive role in three aspects: prediction of disease, prevention of disease and management of disease. Big data enables us to build models that can be used to predict the occurrence of disease. Based on this information, actions can be taken to prevent the disease. Data also helps to manage the disease by offering helpful insights. Medical personnel can retrieve the patient data, with the help of AI, they can make faster decisions allowing them to spend more quality time with the patients and reduce cognitive errors. Through the interviews, it was understood that even though the positive role of big data has been acknowledged, the implementation is still a challenge due to various limitations. The challenges lie mainly on technical know-how and domain knowledge. Further challenges were data security and privacy issues that need to be addressed to mitigate the risks that can be caused by them. The examples of big data implementation in various cases like in heart failure prediction or prevention shows a positive picture. The overwhelming majority of case studies analyzed in this regard show an optimistic picture. Due to growing importance and use of smart devices, IoT, genomics and the recent developments in the field of ICTs, it is expected that big data will not only leave a positive influence on the field of Cardiology, it will also change the way medicine is practiced and healthcare is offered. The statement ‘Data is the new oil’ has been broadly acknowledged due to its wide-ranging importance. Utilizing big data offers a variety of benefits. Although the health sector was late in terms of exploiting the benefits of big data, currently, the adoption is accelerating. Healthcare is increasingly becoming an information science and the implementation of electronic medical records (EMR) and other information systems is growing rapidly. The patient data originating from smart devices and other sources like genomic databases are supporting the healthcare sector offering better healthcare delivery and increasing efficiency, hence saving costs.
Author : Ernst R. Berndt,Dana P. Goldman,John Rowe Publisher : University of Chicago Press Page : 361 pages File Size : 49,5 Mb Release : 2019-04-22 Category : Business & Economics ISBN : 9780226611068
Economic Dimensions of Personalized and Precision Medicine by Ernst R. Berndt,Dana P. Goldman,John Rowe Pdf
Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.
National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease Publisher : National Academies Press Page : 142 pages File Size : 46,8 Mb Release : 2012-01-16 Category : Medical ISBN : 9780309222228
Toward Precision Medicine by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease Pdf
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Roger S. Blumenthal,JoAnne Micale Foody,Nathan D. Wong
Author : Roger S. Blumenthal,JoAnne Micale Foody,Nathan D. Wong Publisher : Saunders Page : 0 pages File Size : 43,6 Mb Release : 2011 Category : Medical ISBN : 1437713661
Preventive Cardiology by Roger S. Blumenthal,JoAnne Micale Foody,Nathan D. Wong Pdf
A new Companion to Braunwald's Heart Disease - addresses the prevention and risk stratification of cardiovascular disease so that you can delay the onset of disease and moderate the effects and complications. Drs. Roger Blumenthal, JoAnne Foody, and Nathan Wong discuss the full range of relevant considerations, including the epidemiology of heart disease, risk assessment, risk factors, multiple risk factor-based prevention strategies, and developments in genetics and personalized medicine.The most authoritative and relevant reference on Prevention of Cardiovascular Diseases is now available!
This volume of the esteemed Progress in Molecular Biology and Translational Science series focuses on cutting-edge research related to the genetics of cardiovascular disease. Written by top experts in the field, this volume covers a range of topics, including: Genetic models of atherosclerosis MicroRNAs in cardiovascular disease The role of the transcription factor KLF2 in vascular development and disease Zebrafish as models of cardiovascular disease and hematopoietic development Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.
Integrative Preventive Medicine by Richard H. Carmona,Mark Liponis Pdf
For most clinicians, the science and evidence for many integrative therapies is largely unknown or considered suspect. Most physicians don't have time to learn integrative approaches and aren't sure what to recommend or which approaches have merit or improved outcomes. Here, clinicians have easy access to the best practices in integrative medicine and expectations for outcomes
Machine Learning in Cardiovascular Medicine by Subhi J. Al'Aref,Gurpreet Singh,Lohendran Baskaran,Dimitri Metaxas Pdf
Machine Learning in Cardiovascular Medicine addresses the ever-expanding applications of artificial intelligence (AI), specifically machine learning (ML), in healthcare and within cardiovascular medicine. The book focuses on emphasizing ML for biomedical applications and provides a comprehensive summary of the past and present of AI, basics of ML, and clinical applications of ML within cardiovascular medicine for predictive analytics and precision medicine. It helps readers understand how ML works along with its limitations and strengths, such that they can could harness its computational power to streamline workflow and improve patient care. It is suitable for both clinicians and engineers; providing a template for clinicians to understand areas of application of machine learning within cardiovascular research; and assist computer scientists and engineers in evaluating current and future impact of machine learning on cardiovascular medicine. Provides an overview of machine learning, both for a clinical and engineering audience Summarize recent advances in both cardiovascular medicine and artificial intelligence Discusses the advantages of using machine learning for outcomes research and image processing Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach
The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.
P5 eHealth: An Agenda for the Health Technologies of the Future by Gabriella Pravettoni,Stefano Triberti Pdf
This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.
