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Author : Anonim
Publisher : Elsevier
Page : 276 pages
File Size : 42,8 Mb
Release : 1975-01-01
Category : Medical
ISBN : 0080862594
Progress in Medicinal Chemistry
Author : ELLIS G. P.
Publisher : Springer
Page : 128 pages
File Size : 44,6 Mb
Release : 1995-12-31
Category : Medical
ISBN : 030630676X
Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry
Publisher : Elsevier
Page : 486 pages
File Size : 51,5 Mb
Release : 2015-06-16
Category : Science
ISBN : 9780128039625
Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. Edited and written by leading experts in medicinal chemistry research Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health
Author : Anonim
Publisher : Unknown
Page : 277 pages
File Size : 47,5 Mb
Release : 1997
Category : Pharmaceutical chemistry
ISBN : OCLC:39693269
Author : Gwynn Pennant Ellis,Geoffrey Buckle West
Publisher : Butterworth-Heinemann
Page : 359 pages
File Size : 43,8 Mb
Release : 1970
Category : Chemistry
ISBN : 9780408700139
PROGRESS IN MEDICINAL CHEMISTRY 7.
Author : Gwynn Pennant Ellis, Geoffrey Buckle West
Publisher : Unknown
Page : 294 pages
File Size : 54,7 Mb
Release : 1985-01-01
Category : Pharmaceutical chemistry
ISBN : 0444806032
Author : G. P. Ellis
Publisher : Elsevier Science Limited
Page : 406 pages
File Size : 41,8 Mb
Release : 1996-01-01
Category : Chemistry
ISBN : OCLC:492155681
Topics of general interest to medicinal chemists, microbiologists, pharmacologists and clinicians are reviewed in this volume. The subjects examined include phosphodiesterase type IV inhibitors and therapeutic potential in the treatment of asthma.
Author : F. D. King,A. W. Oxford
Publisher : Elsevier Science & Technology
Page : 394 pages
File Size : 40,8 Mb
Release : 2001-01-01
Category : Medical
ISBN : 0444506365
Hardbound. Highlights of this volume include comprehensive accounts of the biological rationale, design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and expert evaluation of new technologies in their application to drug action and design.The seven chapters of this volume describe exciting advances in new drug molecules and in the application of new technologies to drug discovery and development.Chapter 1 provides a comprehensive account of p38 mitogen-activated protein kinase inhibitors, a new class of anti-inflammatory agents with potential application to rheumatoid arthritis, inflammatory bowel disease and psoriasis, as well as other disorders with an inflammatory component.A timely review on ligands for adenosine A3 receptors in Chapter 2 focuses on potent and selective agonists and partial agonists derived from adenosine, but demons
Author : Anonim
Publisher : Unknown
Page : 271 pages
File Size : 48,6 Mb
Release : 1981
Category : Cell membranes
ISBN : 0444803459
Author : F.D. King,G. Lawton
Publisher : Elsevier
Page : 232 pages
File Size : 45,6 Mb
Release : 2007-04-13
Category : Science
ISBN : 0080471315
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis. *Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
Author : Anonim
Publisher : Butterworth-Heinemann
Page : 0 pages
File Size : 44,6 Mb
Release : 1962
Category : Electronic
ISBN : 0444533206
Author : G. P. Ellis,Geoffrey Buckle West
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 1961
Category : Pharmaceutical chemistry
ISBN : OCLC:253130693
Author : Edeildo Ferreira Da Silva, Jr.
Publisher : Unknown
Page : 366 pages
File Size : 52,6 Mb
Release : 2019-10-15
Category : Electronic
ISBN : 1536163686
Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting points for the design of drugs against obesity, multidrug-resistant bacteria, neglected tropical diseases, Alzheimer, and cancer. From the prediction of promising hits and identification of active compounds to the extraction of more complex molecules, this book explores a range of essential topics to support the development of novel, economical, and efficacious therapeutics for these diseases, which currently affect a billion people worldwide. Beginning with an overview of obesity, showing the current research landscape, the books shows the importance of natural and synthetic products as promising anti-obesity agents. Subsequently, the medicinal chemistry of modulation of bacterial resistance is presented, focusing on the MFS, RND, ABC, and MATE superfamilies. The book goes on to discuss such topics as antituberculosis, antileishmanial, and anti-hepatitis thiophene-containing compounds, under the medicinal chemistry point of view. Also, potent human glutaminyl cyclase inhibitors are deeply discussed and displayed as hopeful anti-Alzheimer's agents. The last three chapters are focused on the development of researches involving new anticancer agents, initializing with LBDD, SBDD, QSAR, and QM/MM methods applied to the identification of novel promising anticancer compounds. Moreover, IDO1 inhibitors are exhaustively explored and analyzed as a new promise for the immunotherapy of cancer. Finally, a great update on Eg5 kinesin inhibitors is provided, exploring different chemical classes of synthetic and natural compounds, including miscellanea as a new approach for Eg5 inhibition. Combining the expertise of researchers from around the world, this volume aims to support and encourage researches for the development of novel, safe, and active agents against lipase enzyme, bacteria, neglected tropical diseases, Alzheimer, and cancer. The clear narrative truly engages the reader, holding their attention right from the opening of a chapter, and maintaining interest and understanding as a chapter leads into more complex material. Advances in Medicinal Chemistry Research is a book that reviews ongoing developments and recent cutting-edge advances in medicinal chemistry of the most relevant diseases found nowadays, underlining how medicinal chemistry research continues to make significant contributions to the discovery and development of new therapeutic entities. Key Features â¢Chapters written by active specialists and leading experts deeply engaged in the research field of most deadly and limiting diseases for drug discovery. â¢Draws together cutting-edge research advances in medicinal chemistry focused at the obesity, multidrug-resistant microorganisms, Alzheimer, and cancer in a single volume. â¢Highlights the future potential of researches for the medicinal chemistry of most impactful diseases today. â¢Contents addressed to medicinal chemistry, biochemistry, biology, and pharmacy students, professors, and researchers.
Author : Anonim
Publisher : Butterworth-Heinemann
Page : 0 pages
File Size : 52,7 Mb
Release : 1961
Category : Electronic
ISBN : 0408703148
Author : Carlton Anthony Taft,Carlos Henrique Tomich de Paula da Silva
Publisher : Bentham Science Publishers
Page : 249 pages
File Size : 44,8 Mb
Release : 2014-10-10
Category : Medical
ISBN : 9781608059546
This e-book series is recommended for readers who are interested in or work with current theoretical and experimental research in medicinal chemistry, with an emphasis on computer aided-drug design and organic synthesis for therapeutic purposes. The e-book series encompasses the multidisciplinary field of medicinal chemistry which overlaps the knowledge of chemistry, physics, biochemistry, biology and pharmacology. The second volume of the series contains the following topics: -Current State-of-the-Art for Virtual Screening and Docking Methods -Estimating Protein-Ligand Binding Affinity by NMR -ADME/Tox Predictions in Drug Design -Bioisosteric Replacements in Drug Design