Protein Adaptation In Extremophiles

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Protein Adaptation in Extremophiles

Khawar Sohail Siddiqui,Torsten Thomas
Protein Adaptation in Extremophiles Book PDF

Author : Khawar Sohail Siddiqui,Torsten Thomas
Publisher : Nova Publishers
Page : 270 pages
File Size : 55,6 Mb
Release : 2008
Category : Medical
ISBN : 1604560193

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Protein Adaptation in Extremophiles by Khawar Sohail Siddiqui,Torsten Thomas Pdf

Life has evolved in an extraordinary way to deal with the most extreme physical and chemical conditions. Extremophilic (extreme-loving) organisms have been found in the superheated waters of deep ocean vents or the hypersaline and cold lakes of Antarctica and indeed often require the extreme conditions of their habitat to survive and thrive. The cellular machinery of extremophiles has developed unique adaptation strategies to effectively function in their given environment. Much scientific attention has focussed on the adaptation of proteins as they have both structural and catalytic functions and hence play key roles in all cellular processes. Moreover, their ability to perform in or withstand extreme physical and chemical conditions has made extremophilic proteins attractive bio-catalysts for a range of industrial and biotechnological applications. This novel and significant book comprehensively summarises our current understanding regarding the structure-function-stability relationship of extremophilic proteins. Leading experts in the field extensively review and comment on the adaptation of proteins to the whole spectrum of physical and chemical extremes. This book represents an important and indispensable reference for students, teachers and researchers with interest or activities in the fascinating area of extremophiles.

Physiology, Genomics, and Biotechnological Applications of Extremophiles

Gunjal, Aparna B.,Thombre, Rebecca,Parray, Javid A.
Physiology Genomics and Biotechnological Applications of Extremophiles Book PDF

Author : Gunjal, Aparna B.,Thombre, Rebecca,Parray, Javid A.
Publisher : IGI Global
Page : 473 pages
File Size : 45,7 Mb
Release : 2021-12-10
Category : Science
ISBN : 9781799891468

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Physiology, Genomics, and Biotechnological Applications of Extremophiles by Gunjal, Aparna B.,Thombre, Rebecca,Parray, Javid A. Pdf

Extremophiles are organisms that are able to live in extreme conditions due to their unique physiological and genetic adaptations. Extremophiles are harnessed for their extremozymes that have wide applications in biotechnology, pharmaceutics, and industry. Recent developments in genomics and proteomics have helped unravel the mechanism of survival, physiological adaptation, and genomics structure of extremophiles. Physiology, Genomics, and Biotechnological Applications of Extremophiles covers innovative developments in understanding the physiology and biochemistry of extremophiles using the -omics perspective, focuses on the advancement in mechanisms of the extremophiles that makes them able to survive under extreme conditions, and discusses the applications of extremophiles in astrobiology. Covering topics such as genomics and the history and identification of extremophiles, it is ideal for students, professors, researchers, academicians, microbiologists, agricultural scientists, and biotechnologists.

Extremophiles and Their Applications in Medical Processes

Prasanti Babu,Anuj K. Chandel,Om V. Singh
Extremophiles and Their Applications in Medical Processes Book PDF

Author : Prasanti Babu,Anuj K. Chandel,Om V. Singh
Publisher : Springer
Page : 54 pages
File Size : 49,6 Mb
Release : 2014-10-29
Category : Medical
ISBN : 9783319128085

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Extremophiles and Their Applications in Medical Processes by Prasanti Babu,Anuj K. Chandel,Om V. Singh Pdf

Extremophiles are known to thrive under harsh environmental conditions. Many extremophilic bio-products are already used as life-saving drugs. Recent technological advancements of systems biology have opened the door to explore these organisms anew as sources of products that might prove useful in clinical, environmental and drug development.

Thermophiles

Frank Robb,Garabed Antranikian,Dennis Grogan,Arnold Driessen
Thermophiles Book PDF

Author : Frank Robb,Garabed Antranikian,Dennis Grogan,Arnold Driessen
Publisher : CRC Press
Page : 368 pages
File Size : 47,9 Mb
Release : 2007-12-13
Category : Science
ISBN : 1420008854

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Thermophiles by Frank Robb,Garabed Antranikian,Dennis Grogan,Arnold Driessen Pdf

We might think of them as living on the very edge of existence. Referred to as extremophiles, these microorganisms exhibit the most radical capacity for adaptation in those harsh environments that are just barely conducive to the existence of cellular life. Unlocking the mechanisms and understanding the evolutionary development that allows these simple organisms to thrive can teach us much about microbiology in extremis. Highly diverse, these microorganisms are found nearly everywhere. One example, thermophiles are microorganisms that thrive at temperatures above the mesophilic range of 25-40 degrees C. Until recently, due to their extreme environment, the study of thermophiles was limited. However with the advent of new tools, particularly genetic analysis, remarkable strides have been made. Thermophiles: Biology and Technology at High Temperatures presents a cogent summary of the progress made in studying these extremophiles. Discover how thermophiles demonstrate extremes that indicate a lack of evolutionary constraints Much is being learned from the study of thermophiles, especially our understanding of biology at the molecular level and the genetic mechanisms that permit adaptation. Included in this volume is a discussion of protective strategies of thermophiles, including their thermostability, which allow them to maintain functional proteins. It also investigates whether hyperthermophiles employ protein phosphorylation-dephosphryation as a molecular regulatory mechanism, and provides significant clues regarding the synthesis of protein. By studying this extreme example, its subtle, yet exaggerated response mechanisms, and its development over the course of many short-lived generations, we may begin to understand the mechanisms in diseases linked to improper protein folding, and also begin to more fully understand the ingenious design of DNA, and all that such an understanding implies regarding the survival of human life in a rapidly changing environment.

EXTREMOPHILES - Volume II

Charles Gerday ,Nicolas Glansdorff
EXTREMOPHILES Volume II Book PDF

Author : Charles Gerday ,Nicolas Glansdorff
Publisher : EOLSS Publications
Page : 382 pages
File Size : 50,8 Mb
Release : 2009-11-05
Category : Science
ISBN : 9781905839940

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EXTREMOPHILES - Volume II by Charles Gerday ,Nicolas Glansdorff Pdf

Extremophiles is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The extremophiles represent some of the most fascinating organisms on Earth for the simple reason that they inhabit extreme environments characterized by physical and (or) chemical properties which render them totally inhospitable for most of the other organisms. The work has been sub-divided into 6 main topics related to the above mentioned environmental conditions. These topics consist of a general introduction and of several more specialized chapters that have been written by scientists prominent in the field. The chapters cover the description of the biotopes and inhabiting species, their specific characteristics as well as what we know about the molecular mechanisms which constitute the fundamentals of the resistance and adaptation of extremophiles to extreme conditions. The theme “Extremophiles” is headed by two chapters introducing the subject for non-specialists in the field, one covering the basic concepts and the other one giving an overview of the biotopes. These three volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.

Physiological and Biotechnological Aspects of Extremophiles

Richa Salwan,Vivek Sharma
Physiological and Biotechnological Aspects of Extremophiles Book PDF

Author : Richa Salwan,Vivek Sharma
Publisher : Academic Press
Page : 388 pages
File Size : 41,7 Mb
Release : 2020-06-04
Category : Science
ISBN : 9780128183236

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Physiological and Biotechnological Aspects of Extremophiles by Richa Salwan,Vivek Sharma Pdf

Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms. Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications

Polyextremophiles

Joseph Seckbach,Aharon Oren,Helga Stan-Lotter
Polyextremophiles Book PDF

Author : Joseph Seckbach,Aharon Oren,Helga Stan-Lotter
Publisher : Springer Science & Business Media
Page : 626 pages
File Size : 41,9 Mb
Release : 2013-05-13
Category : Science
ISBN : 9789400764880

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Polyextremophiles by Joseph Seckbach,Aharon Oren,Helga Stan-Lotter Pdf

Many Microorganisms and some macro-organisms can live under extreme conditions. For example, high and low temperature, acidic and alkaline conditions, high salt areas, high pressure, toxic compounds, high level of ionizing radiation, anoxia and absence of light, etc. Many organisms inhabit environments characterized by more than one form of stress (Polyextremophiles). Among them are those who live in hypersaline and alkaline, hot and acidic, cold/hot and high hydrostatic pressure, etc. Polyextremophiles found in desert regions have to copy with intense UV irradiation and desiccation, high as well as low temperatures, and low availability of water and nutrients. This book provides novel results of application to polyextremophiles research ranging from nanotechnology to synthetic biology to the origin of life and beyond.

Microbial Extremozymes

Mohammed Kuddus
Microbial Extremozymes Book PDF

Author : Mohammed Kuddus
Publisher : Academic Press
Page : 340 pages
File Size : 41,5 Mb
Release : 2021-08-20
Category : Science
ISBN : 9780128231029

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Microbial Extremozymes by Mohammed Kuddus Pdf

Microbial Extremozymes: Novel Sources and Industrial Applications is a unique resource of practical research information on the latest novel sources and technologies regarding extremozymes in bioremediation, waste management, valorization of industrial by-products, biotransformation of natural polymers, nutrition, food safety and diagnosis of disease. The book's broad knowledge and varying applications are useful to the food industry, dairy industry, fruit and vegetable processing, and baking and beverages industries, as well as the pharmaceutical and biomedical industries. This is a concise, all-encompassing resource for a range of scientists needing knowledge of extremozymes to enhance and research. Furthermore, it provides an updated knowledge of microbial enzymes isolated from extreme environments (temperatures, etc.) and their biotechnological applications. It will be useful to researchers, scientists and students in enzyme research. In addition, users from the dairy and baking industries will benefit from the presented content. Explores recent scientific research on extremophiles and extremozymes technologies that help innovate novel ideas Provides innovative technologies for enzyme production from extremophilic microbes Includes cutting-edge research for applications in various industries where extreme temperature conditions exist Presents novel microorganisms and their enzymes from extreme environments (Thermophilic, Psychrophilic, Acidophilic, Alkaliphilic, Anaerobic, Halophilic, Barophilic, Metallotolerant, Radioresistant, etc.)

Extremophile Fishes

Rüdiger Riesch,Michael Tobler,Martin Plath
Extremophile Fishes Book PDF

Author : Rüdiger Riesch,Michael Tobler,Martin Plath
Publisher : Springer
Page : 326 pages
File Size : 44,7 Mb
Release : 2015-01-24
Category : Science
ISBN : 9783319133621

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Extremophile Fishes by Rüdiger Riesch,Michael Tobler,Martin Plath Pdf

This book summarizes the key adaptations enabling extremophile fishes to survive under harsh environmental conditions. It reviews the most recent research on acidic, Antarctic, cave, desert, hypersaline, hypoxic, temporary, and fast-flowing habitats, as well as naturally and anthropogenically toxic waters, while pointing out generalities that are evident across different study systems. Knowledge of the different adaptations that allow fish to cope with stressful environmental conditions furthers our understanding of basic physiological, ecological, and evolutionary principles. In several cases, evidence is provided for how the adaptation to extreme environments promotes the emergence of new species. Furthermore, a link is made to conservation biology, and how human activities have exacerbated existing extreme environments and created new ones. The book concludes with a discussion of major open questions in our understanding of the ecology and evolution of life in extreme environments.

Archaea

Haitham Sghaier,Afef Najjari,Kaïs Ghedira
Archaea Book PDF

Author : Haitham Sghaier,Afef Najjari,Kaïs Ghedira
Publisher : BoD – Books on Demand
Page : 112 pages
File Size : 44,5 Mb
Release : 2017-10-11
Category : Medical
ISBN : 9789535135692

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Archaea by Haitham Sghaier,Afef Najjari,Kaïs Ghedira Pdf

Besides the Introductory Chapter that gives a brief overview of archaeal applications, the present book contains four chapters. The first chapter, by Castro-Fernandez et al., provides an interesting depiction of the phylum Euryarchaeota and its biotechnological applications. The second chapter, by Ben Hania and coauthors, focuses on the promotion of the idea that some specific Archaea are potential next-generation probiotics. The third chapter, by Torregrosa-Crespo et al., emphasizes the main characteristics of biocompounds from haloarchaea and their potential uses in biomedicine, pharmacy, and industry. The concluding chapter, by Mizuno et al., proposes a plasmid curing approach for improving the potential of thermophiles in various biotechnological applications and opens new perspectives on industrial valorization.

Extremozymes and their Industrial Applications

Naveen Kumar Arora,Shekhar Agnihotri,Jitendra Mishra
Extremozymes and their Industrial Applications Book PDF

Author : Naveen Kumar Arora,Shekhar Agnihotri,Jitendra Mishra
Publisher : Academic Press
Page : 444 pages
File Size : 47,7 Mb
Release : 2022-06-15
Category : Science
ISBN : 9780323904230

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Extremozymes and their Industrial Applications by Naveen Kumar Arora,Shekhar Agnihotri,Jitendra Mishra Pdf

Extremophiles belong to members of all three domains of life, i.e., bacteria, archaea, and eukarya. However, a high proportion of extremophiles are archaea and bacteria. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they not only manage to survive but even thrive in such conditions. Extremophiles have important practical and industrial uses. They are a valuable source of industrially important enzymes also known as extremozymes. Recent research has revealed that extremozymes have unique structural features essential for biocatalysis under extreme conditions. Extremozymes have great commercial values and are known for their potential use in biotechnology, biomining, and bioremediation. Extremozymes and their Industrial Applications highlights the current and topical areas of research in this rapidly growing field of extremophiles and their applications. Expert researchers from around the globe are trying to uncover the underlying mechanisms responsible for their specific adaptations under extreme environments. The topics covered include the ability of acidophiles to maintain a neutral intracellular pH, the way psychrophiles "loosen up" their proteins at low temperatures, and other equally ingenious adaptations and metabolic strategies that extremophiles use to survive and flourish under extreme conditions. Extremozymes and their Industrial Applications also covers the established biotechnological uses of extremophiles and the most recent and novel applications, including their exploitation for enzyme production. Potential use of extremophiles and their enzymes in the generation of sustainable energy, biomass conversion, agro-waste processing, and biocontrol of phytopathogens is also covered. The book will be very useful for researchers and students working in the area of industrial microbiology and biotechnology, and microbial ecologists. It is also recommended reference text for those interested in the biochemistry and microbiology of extremophiles, as well as for those interested in bioprospecting, biomining, biofuels, and biodegradation. Presents information exclusively based on extremozymes and their application in industries Chapters have been collected from various experts and deals with contemporary issues related to extremozymes and their usability in various industries Enriched with suitable illustrations that assist in increasing readership and broaden the reach of the book amongst scholars and academicians

Removal of Emerging Contaminants Through Microbial Processes

Maulin P Shah
Removal of Emerging Contaminants Through Microbial Processes Book PDF

Author : Maulin P Shah
Publisher : Springer Nature
Page : 536 pages
File Size : 40,9 Mb
Release : 2020-10-14
Category : Science
ISBN : 9789811559013

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Removal of Emerging Contaminants Through Microbial Processes by Maulin P Shah Pdf

The abundance of organic pollutants found in wastewater affect urban surface waters. Traditional wastewater management technologies focus on the removal of suspended solids, nutrients and bacteria, however, new pollutants such as synthetic or naturally occurring chemicals are often not monitored in the environment despite having the potential to enter the environment and cause adverse ecological and human health effects. Collectively referred to as "emerging contaminants," they are mostly derived from domestic activities and occur in trace concentrations ranging from pico to micrograms per liter. Environmental contaminants are resistant to conventional wastewater treatment processes and most of them remain unaffected, causing contamination of receiving water. This in turn leads to the need for advanced wastewater treatment processes capable of removing environmental contaminants to ensure safe fresh water sources. This book provides an up-to-date overview of the current bioremediation strategies, including their limitations, challenges and their potential application to remove environmental pollutants. It also introduces the latest trends and advances in environmental bioremediation, and presents the state-of-the-art in biological and chemical wastewater treatment processes. As such, it will appeal to researchers and policy-makers, as well as undergraduate and graduate environmental sciences students.

Extremophiles as Astrobiological Models

Joseph Seckbach,Helga Stan-Lotter
Extremophiles as Astrobiological Models Book PDF

Author : Joseph Seckbach,Helga Stan-Lotter
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 41,6 Mb
Release : 2021-01-13
Category : Science
ISBN : 9781119591689

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Extremophiles as Astrobiological Models by Joseph Seckbach,Helga Stan-Lotter Pdf

The data in this book are new or updated, and will serve also as Origin of Life and evolutionary studies. Endospores of bacteria have a long history of use as model organisms in astrobiology, including survival in extreme environments and interplanetary transfer of life. Numerous other bacteria as well as archaea, lichens, fungi, algae and tiny animals (tardigrades, or water bears) are now being investigated for their tolerance to extreme conditions in simulated or real space environments. Experimental results from exposure studies on the International Space Station and space probes for up to 1.5 years are presented and discussed. Suggestions for extaterrestrial energy sources are also indicated. Audience Researchers and graduate students in microbiology, biochemistry, molecular biology and astrobiology, as well as anyone interested in the search for extraterrestrial life and its technical preparations.

Biotechnology of Bioactive Compounds

Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani
Biotechnology of Bioactive Compounds Book PDF

Author : Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani
Publisher : John Wiley & Sons
Page : 742 pages
File Size : 44,8 Mb
Release : 2015-04-20
Category : Technology & Engineering
ISBN : 9781118733493

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Biotechnology of Bioactive Compounds by Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani Pdf

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Biotechnology of Extremophiles

G. Antranikian
Biotechnology of Extremophiles Book PDF

Author : G. Antranikian
Publisher : Springer
Page : 204 pages
File Size : 50,6 Mb
Release : 1998-05-15
Category : Medical
ISBN : UOM:39015041786024

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Biotechnology of Extremophiles by G. Antranikian Pdf

In this special issue review articles summarize the most outstanding features of microorganisms that can survive under extreme conditions. These microorganisms are adapted to living at 100° C in volcanic springs, at low temperatures in the cold polar seas, at high pressure in the deep sea, at very low and high pH values (pH 0-1 or pH 10-11), or at very high salt concentrations (35%). The latest findings on the molecular biology and the protein structure of these exotic organisms are presented. In addition, the potential applications of extremophiles are reviewed, including the production of enzymes, compatible solutes and the use of these extremophiles in the degradation of xenobiotics.