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Protein Electrophoresis in Clinical Diagnosis by David Keren Pdf
Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques,
Author : Stephen M. Palfrey Publisher : Springer Science & Business Media Page : 215 pages File Size : 46,6 Mb Release : 2008-02-01 Category : Medical ISBN : 9781592596898
Clinical Applications of Capillary Electrophoresis by Stephen M. Palfrey Pdf
In Clinical Applications of Capillary Electrophoresis, Stephen Palfrey brings together for first time a collection of detailed capillary electrophoresis protocols designed exclusively for clinical applications. Written by the leading scientists who have often perfected these methods in their own laboratories, the protocols furnish new and more powerful assays for many routine serum and blood tests now regularly performed in clinical laboratories, including urine protein analysis, hemoglobin separation, and the detection of CSF proteins, lipoproteins, myoglobin, cryoglobulins, HbA1c, and cathepsin. The protocols offered for DNA studies include double-stranded DNA analysis, the prenatal diagnosis of Down's syndrome, Rh D/d genotyping, the identification of mutated p53 oncogene, and the detection of microsatellite instability in cancers. Many of the methods can be automated to replace the more costly and labor-intensive tests that are currently used in most clinical laboratories. Clinical Applications of Capillary Electrophoresis demonstrates clearly the simplicity, versatility, and power of CE over conventional methods. It offers to beginning clinical investigators, as well as established laboratories new to the technique, a representative range of highly practical CE methods-assays that are not only certain to become ever more productive, but are already eminently useful today.
High-Resolution Electrophoresis and Immunofixation by David F. Keren Pdf
High-Resolution Electrophoresis and Immunofixation: Techniques and Interpretation acquaints the reader with the available methodologies and instrumentation for performing high-resolution electrophoresis and immunofixation. This text presents the use of procedures of high-resolution electrophoresis and immunofixation to facilitate the diagnosis of a variety of serum protein abnormalities. It also provides case examples to illustrate the uses of these procedures and their possible caveats. The book contains chapters devoted to the methods and rationale for high-resolution electrophoresis; interpretation of high-resolution electrophoresis patterns in serum, urine, and cerebrospinal fluid; the immunofixation technique; and strategies for diagnosing monoclonal gammopathies. Medical technologists, physicians, and pathologists will find the book invaluable.
Multiple Myeloma and Related Serum Protein Disorders by Neil S. Harris, MD,William E. Winter Pdf
Multiple Myeloma and Related Serum Protein Disorders is a practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens. Multiple Myeloma and Related Serum Protein Disorders serves as a practical guide for clinical pathologists as well as pathology residents, clinical laboratory scientists and medical technologists. Multiple Myeloma and Related Serum Protein Disorders Features Include: Covers both serum (blood) and urine electrophoresis Covers immunofixation electrophoresis Particular attention to differentiating false negative and false positive reports Well-illustrated throughout Concise, practical guide for practitioners and residents
Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf
A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Mass Spectrometry for Microbial Proteomics by Haroun N. Shah,Saheer E. Gharbia Pdf
New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections that follow the general progression in which most microbiology laboratories are approaching the subject –Transition, Tools, Preparation, Profiling by Patterns, Target Proteins, and Data Analysis.
Protein Electrophoresis in Clinical Diagnosis by David Keren Pdf
Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques, immunofixation techniques, approaches to pattern interpretation, and pattern interpretation in both cerebralspinal fluid and urine. Conditions associated with Monoclunal Gammopathies are considered, as are the appropriate strategies for their detection. David Keren is well-known as the leader in this field, his work on guidelines becoming the benchmark for all those involved in protein detection in serum and urine. Dr Keren's book will be essential in every laboratory, and read by pathologists, chemical chemists, medical technicians and clinicians (particularly hematologists and oncologists).
Laboratory Screening and Diagnostic Evaluation by Kelly Small Casler, DNP, APRN, FNP-BC, CHSE,Kate Sustersic Gawlik, DNP, APRN-CNP, FAANP Pdf
"[the authors] did a masterful job of creating and editing this gold standard book that should be used by all clinicians and incorporated into all nursing and health sciences curriculums." -Bernadette Mazurek Melnyk, PhD, APRN-CNP, FNAP, FAANP, FAAN Vice President for Health Promotion University Chief Wellness Officer Dean and Helene Fuld Health Trust Professor of Evidence-Based Practice, College of Nursing Professor of Pediatrics & Psychiatry, College of Medicine Executive Director, the Helene Fuld Health Trust National Institute for EBP The Ohio State University This is the only book to explicitly guide clinicians through an evidence-based approach to ordering and interpreting laboratory tests. With over 160 commonly ordered tests, this book is designed to foster more accurate clinical decision-making to attain the highest level of patient care. This book summarizes more than 3000 pieces of evidence and incorporates clinical expertise and decision-making on the ordering and interpretation of tests. To promote ease of use, a convenient table maps labs and their corresponding chapter numbers to the relevant body system to promote ease of use. Each laboratory test is presented in a consistent format with information on physiology, indications (screening, diagnosis, and monitoring), algorithms, test interpretation and follow-up testing, patient education, and related diagnoses. Additional valuable features include clinical pearls that highlight common pitfalls and gaps in reasoning, and a cost-benefit analysis. This book also includes CPT and ICD-10 codes, charts and tables for clarification, and references for further study. Key Features: Delivers a strong, evidence-based approach to ordering and interpreting over 160 laboratory tests Promotes accurate clinical decision-making toward achieving the Triple Aim Includes abundant clinical pearls highlighting common pitfalls and gaps in reasoning Provides cost-benefit analysis and discussion of laboratory testing within a high-value healthcare culture Includes 175 supplemental case examples and 200 self-assessment questions to facilitate instruction and learning Includes more than 3000 pieces of evidence from interprofessional resources
Multiple Myeloma by Morie A. Gertz,S. Vincent Rajkumar Pdf
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Author : Eric P. Cohen Publisher : Oxford University Press, USA Page : 382 pages File Size : 45,9 Mb Release : 2010-11-11 Category : Medical ISBN : 9780199580194
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.