Protein Geometry Classification Topology And Symmetry

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Protein Geometry, Classification, Topology and Symmetry

William R. Taylor,Andras Aszodi
Protein Geometry Classification Topology and Symmetry Book PDF

Author : William R. Taylor,Andras Aszodi
Publisher : CRC Press
Page : 348 pages
File Size : 54,7 Mb
Release : 2004-10-01
Category : Science
ISBN : 9781420033632

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Protein Geometry, Classification, Topology and Symmetry by William R. Taylor,Andras Aszodi Pdf

Using a geometric perspective, Protein Geometry, Classification, Topology, and Symmetry reviews and analyzes the structural principals of proteins with the goal of revealing the underlying regularities in their construction. It also reviews computer methods for structure analysis and the automatic comparison and classification of these structures with an analysis of the statistical significance of comparing different shapes. Following an analysis of the current state of protein classification, the authors explore more abstract geometric and topological representations, including the occurrence of knotted topologies. The book concludes with a consideration of the origin of higher-level symmetries in protein structure. The authors focus on simple geometric methods that are deterministic rather than probabilistic and on the more abstract simplifications of protein structure that allow a better understanding of the overall fold of the structure. Most of the methods described in this book have corresponding computer programs. These can be found (as C source code) at the ftp site of the Division of Mathematical Biology at the National Institute for Medical Research. This collection of ideas contains pedagogical material that make it ideal for post-graduate courses as well as new ideas and results essential for researchers investigating protein structures.

Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers

Robert B. Northrop,Anne N. Connor
Introduction to Molecular Biology Genomics and Proteomics for Biomedical Engineers Book PDF

Author : Robert B. Northrop,Anne N. Connor
Publisher : CRC Press
Page : 480 pages
File Size : 49,8 Mb
Release : 2008-10-28
Category : Medical
ISBN : 9781420061215

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Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers by Robert B. Northrop,Anne N. Connor Pdf

Illustrates the Complex Biochemical Relations that Permit Life to Exist It can be argued that the dawn of the 21st century has emerged as the age focused on molecular biology, which includes all the regulatory mechanisms that make cellular biochemical reaction pathways stable and life possible. For biomedical engineers, this concept is essential to their chosen profession. Introduction to Molecular Biology, Genomics, and Proteomics for Biomedical Engineers hones in on the specialized organic molecules in living organisms and how they interact and react. The book’s sound approach to this intricately complex field makes it an exceptional resource for further exploration into the biochemistry, molecular biology, and genomics fields. It is also beneficial for electrical, chemical, and civil engineers as well as biophysicists with an interest in modeling living systems. This seminal reference includes many helpful tools for self study, including— 143 illustrations, 32 in color, to bolster understanding of complex biochemical relations 20 tables for quick access to precise data 100 key equations Challenging self-study problems within each chapter Conveys Human Progress in the Manipulation of Genomes at the Molecular Level In response to growing global interest in biotechnology, this valuable text sheds light on the evolutionary theories and future trends in genetic medicine and stem cell research. It provides a broader knowledge base on life-permitting complexities, illustrates how to model them quantitatively, and demonstrates how to manipulate them in genomic-based medicine and genetic engineering. Consequently, this book allows for a greater appreciation among of the incredible complexity of the biochemical systems required to sustain life in its many forms. A solutions manual is available for instructors wishing to convert this reference to classroom use.

Biomedical Materials

Roger Narayan
Biomedical Materials Book PDF

Author : Roger Narayan
Publisher : Springer Nature
Page : 728 pages
File Size : 43,8 Mb
Release : 2020-12-09
Category : Technology & Engineering
ISBN : 9783030492069

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Biomedical Materials by Roger Narayan Pdf

This second edition provides a comprehensive discussion of contemporary materials used in biomedical research and development. The pedagogical writing style and structure provides students with an understanding of the fundamental concepts necessary to pursue research and industrial work in this growing area of biomedical science, including characteristics of biomaterials, biological processes, biocompatibility, and applications of materials in implants and medical instruments. Written by leading researchers in the field, this volume highlights important topics associated with biomedical engineering, medicine and surgery. The revised text contains updates that reflect recent technological advances in biomedical materials. It contains information on new characterization methods and applications for biomedical materials and incorporates suggestions that were offered by readers and educators using the first edition over the years. This textbook takes the reader to the forefront of biomedical materials development, providing graduate students with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.

Fractal Symmetry of Protein Interior

Anirban Banerji
Fractal Symmetry of Protein Interior Book PDF

Author : Anirban Banerji
Publisher : Springer Science & Business Media
Page : 84 pages
File Size : 40,9 Mb
Release : 2014-07-08
Category : Science
ISBN : 9783034806510

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Fractal Symmetry of Protein Interior by Anirban Banerji Pdf

The essential question that fractal dimensions attempt to answer is about the scales in Nature. For a system as non-idealistic and complex as a protein, studying scale-invariance becomes particularly important. Fractal Symmetry of Protein Interior investigates the diverse facets of the various scales at which we describe protein biophysical and biochemical phenomena. Following a thorough introduction to fractal dimensions, fractal-dimension-based approaches, that have been employed to study protein interior biophysical properties, are described. The focus is on the question “which scales are scale-invariant?” Investigations related to scaling of biophysical and biochemical behaviors may one day help us to formulate a fundamental theory about protein biophysics; which, in turn, may help us to understand fundamental principles of proteins.

Innovations in Biomolecular Modeling and Simulations

Tamar Schlick
Innovations in Biomolecular Modeling and Simulations Book PDF

Author : Tamar Schlick
Publisher : Royal Society of Chemistry
Page : 380 pages
File Size : 51,6 Mb
Release : 2012-05-24
Category : Science
ISBN : 9781849735049

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Innovations in Biomolecular Modeling and Simulations by Tamar Schlick Pdf

The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and breakthroughs in computer technology - has opened new avenues of opportunity as never before. Now, experimental data can be interpreted and further analysed by modeling, and predictions from any approach can be tested and advanced through companion methodologies and technologies. This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts. With contributions from experts in the field, the books describe progress and innovation in areas including: simulation algorithms for dynamics and enhanced configurational sampling, force field development, implicit solvation models, coarse-grained models, quantum-mechanical simulations, protein folding, DNA polymerase mechanisms, nucleic acid complexes and simulations, RNA structure analysis and design and other important topics in structural biology modeling. The books are aimed at graduate students and experts in structural biology and chemistry and the emphasis is on reporting innovative new approaches rather than providing comprehensive reviews on each subject.

Protein-Protein Interactions

Krishna Mohan Poluri,Khushboo Gulati,Sharanya Sarkar
Protein Protein Interactions Book PDF

Author : Krishna Mohan Poluri,Khushboo Gulati,Sharanya Sarkar
Publisher : Springer Nature
Page : 346 pages
File Size : 43,8 Mb
Release : 2021-05-19
Category : Science
ISBN : 9789811615948

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Protein-Protein Interactions by Krishna Mohan Poluri,Khushboo Gulati,Sharanya Sarkar Pdf

This book provides a comprehensive overview of the fundamental aspects of protein-protein interactions (PPI), including a detailed account of the energetics and thermodynamics involved in these interactions. It also discusses a number of computational and experimental approaches for the prediction of PPI interactions and reviews their principles, advantages, drawbacks, and the recent developments. Further, it offers structural and mechanistic insights into the formation of protein-protein complexes and maps different PPIs into networks to delineate various pathways that operate at the cellular level. Lastly, it describes computational protein-protein docking techniques and discusses their implications for further experimental research. Given its scope, this book is a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Protein Interactions

Volkhard Helms,Olga V. Kalinina
Protein Interactions Book PDF

Author : Volkhard Helms,Olga V. Kalinina
Publisher : John Wiley & Sons
Page : 436 pages
File Size : 52,6 Mb
Release : 2023-02-06
Category : Science
ISBN : 9783527348640

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Protein Interactions by Volkhard Helms,Olga V. Kalinina Pdf

A fundamental guide to the burgeoning field of protein interactions From enzymes to transcription factors to cell membrane receptors, proteins are at the heart of biological cell function. Virtually all cellular processes are governed by their interactions, with one another, with cell bodies, with DNA, or with small molecules. The systematic study of these interactions is called Interactomics, and research within this new field promises to shape the future of molecular cell biology. Protein Interactions goes beyond any existing guide to protein interactions, presenting the first truly comprehensive overview of the field. Edited by two leading scholars in the field of protein bioinformatics, this book covers all known categories of protein interaction, stable as well as transient, as well as the effect of mutations and post-translational modifications on the interaction behavior. Protein Interactions readers will also find: Introductory chapters on protein structure, conformational dynamics, and protein-protein binding interfaces A data-driven approach incorporating machine learning and integrating experimental data into computational models An outlook on the current challenges in the field and suggestions for future research Protein Interactions will serve as a fundamental resource for novice researchers who want a systematic introduction to interactomics, as well as for experienced cell biologists and bioinformaticians who want to gain an edge in this exciting new field.

Geometry and Topology in Hamiltonian Dynamics and Statistical Mechanics

Marco Pettini
Geometry and Topology in Hamiltonian Dynamics and Statistical Mechanics Book PDF

Author : Marco Pettini
Publisher : Springer Science & Business Media
Page : 456 pages
File Size : 41,5 Mb
Release : 2007-06-14
Category : Mathematics
ISBN : 9780387499574

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Geometry and Topology in Hamiltonian Dynamics and Statistical Mechanics by Marco Pettini Pdf

This book covers a new explanation of the origin of Hamiltonian chaos and its quantitative characterization. The author focuses on two main areas: Riemannian formulation of Hamiltonian dynamics, providing an original viewpoint about the relationship between geodesic instability and curvature properties of the mechanical manifolds; and a topological theory of thermodynamic phase transitions, relating topology changes of microscopic configuration space with the generation of singularities of thermodynamic observables. The book contains numerous illustrations throughout and it will interest both mathematicians and physicists.

Book Review Index

Anonim
Book Review Index Book PDF

Author : Anonim
Publisher : Unknown
Page : 1426 pages
File Size : 52,9 Mb
Release : 2006
Category : Books
ISBN : UOM:39015066121404

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Book Review Index by Anonim Pdf

Every 3rd issue is a quarterly cumulation.

Fractal Symmetry of Protein Exterior

Anirban Banerji
Fractal Symmetry of Protein Exterior Book PDF

Author : Anirban Banerji
Publisher : Springer Science & Business Media
Page : 55 pages
File Size : 45,5 Mb
Release : 2013-04-18
Category : Science
ISBN : 9783034806541

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Fractal Symmetry of Protein Exterior by Anirban Banerji Pdf

The essential question that fractal dimensions attempt to answer is about the scales in Nature. For a system as non-idealistic and complex as a protein, studying scale-invariance becomes particularly important. Fractal Symmetry of Protein Exterior investigates the diverse facets of the various scales at which we describe protein biophysical and biochemical phenomena. Although these ideas are entirely mathematical, mathematical expositions have been avoided, unless the use of some expressions becomes absolutely obligatory. A first chapter introduce into fractal dimensions, protein exteriors and to methods to study the roughness of surfaces. The main topics covered in the following chapters include: protein-protein interaction interfaces; protein surface-roughness and local shape as well as adhesion on protein and other rough biomolecular surfaces.

Chemical Topology

Danail Bonchev,Dennis H Rouvray
Chemical Topology Book PDF

Author : Danail Bonchev,Dennis H Rouvray
Publisher : CRC Press
Page : 392 pages
File Size : 55,5 Mb
Release : 2000-07-06
Category : Science
ISBN : 9056992406

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Chemical Topology by Danail Bonchev,Dennis H Rouvray Pdf

Topology has been extensively applied in the study of chemically linked and knotted structures, and also in the study of many biologically significant molecules such as proteins and DNA. These are the themes that are addressed in this volume of the Mathematical Chemistry series. The topological chirality of knotted and linked molecular species and the invariants that may characterize them are explored in detail.

Protein Structure and Function

Gregory A. Petsko,Dagmar Ringe
Protein Structure and Function Book PDF

Author : Gregory A. Petsko,Dagmar Ringe
Publisher : New Science Press
Page : 220 pages
File Size : 41,5 Mb
Release : 2004
Category : Proteins
ISBN : 9780878936632

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Protein Structure and Function by Gregory A. Petsko,Dagmar Ringe Pdf

Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Biomembrane Transport

Lon J. Van Winkle
Biomembrane Transport Book PDF

Author : Lon J. Van Winkle
Publisher : Elsevier
Page : 397 pages
File Size : 47,8 Mb
Release : 1999-05-20
Category : Science
ISBN : 0080528104

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Biomembrane Transport by Lon J. Van Winkle Pdf

Biomembrane Transport covers the fundamental principles of biomembrane transport proteins, including thermodynamics and kinetics, structure and catalytic mechanism, and regulation and integration classification. The book considers recent advances in transport protein structure and function, along with established concepts. The importance of biomembrane transport to regulation and interorgan nutrient flows and metabolism is covered, as well as classical and modern techniques for characterizing transport. The book also contains a classification scheme for all known transport proteins according to their functions and amino acid residue sequence similarities. Considers recent advances in transport protein structure and function, along with established concepts Distinguishes the similarities and differences in the mechanisms of action of transport proteins Provides an up-to-date discussion of the thermodynamics and kinetics of biomembrane transport Discusses regulation of biomembrane transport Details the importance of biomembrane transport to regulation and interorgan nutrient flows and metabolism Contains a classification scheme for all known transport proteins according to their functions and amino acid residue sequence similarities Presents classical and modern techniques for characterizing transport

Handbook on Metalloproteins

Ivano Bertini,Astrid Sigel
Handbook on Metalloproteins Book PDF

Author : Ivano Bertini,Astrid Sigel
Publisher : CRC Press
Page : 1382 pages
File Size : 51,6 Mb
Release : 2001-06-29
Category : Medical
ISBN : 0824705203

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Handbook on Metalloproteins by Ivano Bertini,Astrid Sigel Pdf

This Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the common and distinct characterstics of metallo- enzymes, proteins, and amino acids bonded to copper, zinc, iron, and more.

Encyclopedia of Bioinformatics and Computational Biology

Anonim
Encyclopedia of Bioinformatics and Computational Biology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 44,8 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases