Psychoses Of The Schizophrenic Spectrum In Twins

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Psychoses of the Schizophrenic Spectrum in Twins

Ernst Franzek,Helmut Beckmann
Psychoses of the Schizophrenic Spectrum in Twins Book PDF

Author : Ernst Franzek,Helmut Beckmann
Publisher : Springer Science & Business Media
Page : 156 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709163535

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Psychoses of the Schizophrenic Spectrum in Twins by Ernst Franzek,Helmut Beckmann Pdf

Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.

The Epidemiology of Schizophrenia

Robin M. Murray,Peter B. Jones,Ezra Susser,Jim Van Os,Mary Cannon
The Epidemiology of Schizophrenia Book PDF

Author : Robin M. Murray,Peter B. Jones,Ezra Susser,Jim Van Os,Mary Cannon
Publisher : Cambridge University Press
Page : 474 pages
File Size : 40,6 Mb
Release : 2002-11-28
Category : Medical
ISBN : 9781139439480

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The Epidemiology of Schizophrenia by Robin M. Murray,Peter B. Jones,Ezra Susser,Jim Van Os,Mary Cannon Pdf

An international team of leading researchers and clinicians here provide a comprehensive, epidemiological overview of this multi-faceted and still perplexing disorder, and address some of the key questions it raises. How important in the genetic contribution to schizophrenia? Do pregnancy and birth complications increase the risk for schizophrenia? Is the incidence of schizophrenia changing? Why is the rate higher among immigrants and in those born in cities? Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth, and separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered. Drawing together the findings from social, genetic, developmental and classical epidemiology of schizophrenia, this text will prove an invaluable resource for clinicians and researchers.

Fix What You Can

Mindy Greiling
Fix What You Can Book PDF

Author : Mindy Greiling
Publisher : U of Minnesota Press
Page : 292 pages
File Size : 46,8 Mb
Release : 2020-10-06
Category : Psychology
ISBN : 9781452963853

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Fix What You Can by Mindy Greiling Pdf

One mother’s fight to support her son and change a broken system In his early twenties, Mindy Greiling’s son, Jim, was diagnosed with schizoaffective disorder after experiencing delusions that demanded he kill his mother. At the time, and for more than a decade after, Greiling was a Minnesota state legislator who struggled, along with her husband, to navigate and improve the state’s inadequate mental health system. Fix What You Can is an illuminating and frank account of caring for a person with a mental illness, told by a parent and advocate. Greiling describes challenges shared by many families, ranging from the practical (medication compliance, housing, employment) to the heartbreaking—suicide attempts, victimization, and illicit drug use. Greiling confronts the reality that some people with serious mental illness may be dangerous and reminds us that medication works—if taken. The book chronicles her efforts to pass legislation to address problems in the mental health system, including obstacles to parental access to information and insufficient funding for care and research. It also recounts Greiling’s painful memories of her grandmother, who was confined in an institution for twenty-three years—recollections that strengthen her determination that Jim’s treatment be more humane. Written with her son’s cooperation, Fix What You Can offers hard-won perspective, practical advice, and useful resources through a brave and personal story that takes the long view of what success means when coping with mental illness.

Schizo-Obsessive Disorder

Michael Poyurovsky
Schizo Obsessive Disorder Book PDF

Author : Michael Poyurovsky
Publisher : Cambridge University Press
Page : 249 pages
File Size : 49,5 Mb
Release : 2013-01-17
Category : Medical
ISBN : 9781107000124

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Schizo-Obsessive Disorder by Michael Poyurovsky Pdf

This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.

Vulnerability to Psychosis

Paolo Fusar-Poli,Stefan J. Borgwardt,Philip McGuire
Vulnerability to Psychosis Book PDF

Author : Paolo Fusar-Poli,Stefan J. Borgwardt,Philip McGuire
Publisher : Psychology Press
Page : 209 pages
File Size : 54,9 Mb
Release : 2013-06-17
Category : Medical
ISBN : 9781136596391

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Vulnerability to Psychosis by Paolo Fusar-Poli,Stefan J. Borgwardt,Philip McGuire Pdf

Early clinical intervention in psychosis is now a major objective of mental health services and the development of specialist intervention services has greatly facilitated research on the early phases of this disorder. In this book, contributors provide a review of the neurobiological research in people at high risk of psychosis, focusing on the transition from being at a high risk state to their first episode. Contributors consider unaffected family members and twin studies as well as the individual’s data before and after the onset of the illness. The environmental factors that contribute to a psychotic episode are also examined. Vulnerability to Psychosis presents neurobiological findings in the context of what is now known about the psychopathology and cognitive impairments that are evident in people at high risk of psychosis. It will be essential reading for clinicians working with this client group, and will interest academics looking for state of the art information in this field.

Molecular Neuropathology

Gareth W. Roberts,Julia M. Polak
Molecular Neuropathology Book PDF

Author : Gareth W. Roberts,Julia M. Polak
Publisher : Cambridge University Press
Page : 204 pages
File Size : 47,9 Mb
Release : 1995-06-08
Category : Medical
ISBN : 0521425581

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Molecular Neuropathology by Gareth W. Roberts,Julia M. Polak Pdf

This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.

Cognitive-behavioral Therapy with Adults

Stefan Hofmann,Mark Reinecke
Cognitive behavioral Therapy with Adults Book PDF

Author : Stefan Hofmann,Mark Reinecke
Publisher : Cambridge University Press
Page : 128 pages
File Size : 54,5 Mb
Release : 2010-10-28
Category : Medical
ISBN : 9781139493642

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Cognitive-behavioral Therapy with Adults by Stefan Hofmann,Mark Reinecke Pdf

Cognitive-behavioral therapy has developed hugely over the past 30 years and is the branch of psychotherapy which has most successfully transferred into the mainstream of treating mental health problems. In this volume, readers will be provided with an integrated, systematic approach for conceptualizing and treating disorders commonly encountered in clinical practice. A strong emphasis is placed on empirically supported approaches to assessment and intervention while offering readers hands-on recommendations for treating common mental disorders, grounded in evidence-based medicine. Practical chapters written by a variety of international experts include numerous case studies demonstrating the specific techniques and addressing common problems encountered and how to overcome them. Cognitive-behavioral Therapy with Adults is an essential guide for practising clinicians and students of cognitive-behavioral therapy as well as educated consumers and those interested in psychotherapy for common mental disorders.

The Neurobiology of Schizophrenia

Ted Abel,Thomas Nickl-Jockschat
The Neurobiology of Schizophrenia Book PDF

Author : Ted Abel,Thomas Nickl-Jockschat
Publisher : Academic Press
Page : 468 pages
File Size : 52,8 Mb
Release : 2016-07-08
Category : Science
ISBN : 9780128018774

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The Neurobiology of Schizophrenia by Ted Abel,Thomas Nickl-Jockschat Pdf

The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Models of Madness

Dr John Read,Professor Richard Bentall,Loren Mosher,John Read,Jacqui Dillon
Models of Madness Book PDF

Author : Dr John Read,Professor Richard Bentall,Loren Mosher,John Read,Jacqui Dillon
Publisher : Routledge
Page : 489 pages
File Size : 47,6 Mb
Release : 2013-06-19
Category : Psychology
ISBN : 9781134055029

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Models of Madness by Dr John Read,Professor Richard Bentall,Loren Mosher,John Read,Jacqui Dillon Pdf

Are hallucinations and delusions really symptoms of an illness called ‘schizophrenia’? Are mental health problems really caused by chemical imbalances and genetic predispositions? Are psychiatric drugs as effective and safe as the drug companies claim? Is madness preventable? This second edition of Models of Madness challenges those who hold to simplistic, pessimistic and often damaging theories and treatments of madness. In particular it challenges beliefs that madness can be explained without reference to social causes and challenges the excessive preoccupation with chemical imbalances and genetic predispositions as causes of human misery, including the conditions that are given the name 'schizophrenia'. This edition updates the now extensive body of research showing that hallucinations, delusions etc. are best understood as reactions to adverse life events and that psychological and social approaches to helping are more effective and far safer than psychiatric drugs and electroshock treatment. A new final chapter discusses why such a damaging ideology has come to dominate mental health and, most importantly, how to change that. Models of Madness is divided into three sections: Section One provides a history of madness, including examples of violence against the ‘mentally ill’, before critiquing the theories and treatments of contemporary biological psychiatry and documenting the corrupting influence of drug companies. Section Two summarises the research showing that hallucinations, delusions etc. are primarily caused by adverse life events (eg. parental loss, bullying, abuse and neglect in childhood, poverty, etc) and can be understood using psychological models ranging from cognitive to psychodynamic. Section Three presents the evidence for a range of effective psychological and social approaches to treatment, from cognitive and family therapy to primary prevention. This book brings together thirty-seven contributors from ten countries and a wide range of scientific disciplines. It provides an evidence-based, optimistic antidote to the pessimism of biological psychiatry. Models of Madness will be essential reading for all involved in mental health, including service users, family members, service managers, policy makers, nurses, clinical psychologists, psychiatrists, psychotherapists, counsellors, psychoanalysts, social workers, occupational therapists, art therapists.

Estrogen — Mystery Drug for the Brain?

Christian Behl
Estrogen Mystery Drug for the Brain Book PDF

Author : Christian Behl
Publisher : Springer Science & Business Media
Page : 256 pages
File Size : 47,9 Mb
Release : 2011-06-28
Category : Medical
ISBN : 9783709161890

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Estrogen — Mystery Drug for the Brain? by Christian Behl Pdf

It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.

Cognitive Impairment in Schizophrenia

Philip D. Harvey
Cognitive Impairment in Schizophrenia Book PDF

Author : Philip D. Harvey
Publisher : Cambridge University Press
Page : 341 pages
File Size : 41,6 Mb
Release : 2013-01-24
Category : Medical
ISBN : 9781107013209

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Cognitive Impairment in Schizophrenia by Philip D. Harvey Pdf

Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.

Essential Psychiatry

Robin M. Murray,Kenneth S. Kendler,Peter McGuffin,Simon Wessely,David J. Castle
Essential Psychiatry Book PDF

Author : Robin M. Murray,Kenneth S. Kendler,Peter McGuffin,Simon Wessely,David J. Castle
Publisher : Cambridge University Press
Page : 1385 pages
File Size : 50,5 Mb
Release : 2008-09-18
Category : Medical
ISBN : 9781139473651

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Essential Psychiatry by Robin M. Murray,Kenneth S. Kendler,Peter McGuffin,Simon Wessely,David J. Castle Pdf

This is a major international textbook for psychiatrists and other professionals working in the field of mental healthcare. With contributions from opinion-leaders from around the globe, this book will appeal to those in training as well as to those further along the career path seeking a comprehensive and up-to-date overview of effective clinical practice backed by research evidence. The book is divided into cohesive sections moving from coverage of the tools and skills of the trade, through descriptions of the major psychiatric disorders and on to consider special topics and issues surrounding service organization. The final important section provides a comprehensive review of treatments covering all of the major modalities. Previously established as the Essentials of Postgraduate Psychiatry, this new and completely revised edition is the only book to provide this depth and breadth of coverage in an accessible, yet authoritative manner.

Principles of Psychiatric Genetics

John I. Nurnberger,Wade Berrettini
Principles of Psychiatric Genetics Book PDF

Author : John I. Nurnberger,Wade Berrettini
Publisher : Cambridge University Press
Page : 415 pages
File Size : 50,7 Mb
Release : 2012-09-13
Category : Medical
ISBN : 9780521896498

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Principles of Psychiatric Genetics by John I. Nurnberger,Wade Berrettini Pdf

A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

Search for the Causes of Schizophrenia

W.F. Gattaz,H. Häfner
Search for the Causes of Schizophrenia Book PDF

Author : W.F. Gattaz,H. Häfner
Publisher : Springer Science & Business Media
Page : 469 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783798519534

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Search for the Causes of Schizophrenia by W.F. Gattaz,H. Häfner Pdf

- The topics covered in the six sections of the book are Epidemiology and Environment, Precursors, Pathophysiological Mechanisms, Genetics, Controversies in Schizophrenia, and Treatment. - Reflects the progress made on Schizophrenia since 1986.

Reducing Risks for Mental Disorders

Institute of Medicine,Committee on Prevention of Mental Disorders
Reducing Risks for Mental Disorders Book PDF

Author : Institute of Medicine,Committee on Prevention of Mental Disorders
Publisher : National Academies Press
Page : 636 pages
File Size : 41,8 Mb
Release : 1994-01-01
Category : Medical
ISBN : 9780309049399

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Reducing Risks for Mental Disorders by Institute of Medicine,Committee on Prevention of Mental Disorders Pdf

The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.