Author : Bengt Robertson,Lambert M. G. van Golde,Joseph J. Batenburg
Publisher : Elsevier Publishing Company
Page : 800 pages
File Size : 42,8 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015029244137
Pulmonary Surfactant by Bengt Robertson,Lambert M. G. van Golde,Joseph J. Batenburg Pdf
There has been a spectacular development in both basic research on the pulmonary surfactant system and the clinical use of surfactant for treatment of lung diseases, especially in the neonatal period. In particular, the molecular biology and physiological roles of the surfactant-associated proteins (SP-A) have been clarified during the last few years; the structure and functions of these proteins therefore constitute an important hot topic, and are reviewed in several chapters of this volume. including surface chemistry and ultrastructure of surfactant components, the role of surfactant in lung mechanics and alveolar liquid homeostasis, and surfactant metabolism and its hormonal control. However, as mentioned above, clinical applications of surfactant research have become increasingly important and are therefore dealt with extensively in the remaining chapters. during the last few years to illustrate the fascinating complexity of the surfactant system. Hence, the main mission of this volume is to catalyze the future development in this field with the exchange of ideas between scientific workers from different disciplines.