Pumps Transporters And Ion Channels

Author : Francisco Sepulveda,Francisco Bezanilla
Publisher : Springer Science & Business Media
Page : 175 pages
File Size : 46,5 Mb
Release : 2006-03-30
Category : Science
ISBN : 9780387274249

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Pumps, Transporters, and Ion Channels by Francisco Sepulveda,Francisco Bezanilla Pdf

This book is a compilation of articles based on some of the talks given at the Centro de Estudios Cientificos (CECS) in Valdivia during the course of a celebration to th mark the 60 birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre is one of the most outstanding figures in channel Biophysics today. The first surprise is that he trained as a Biochemist! He soon, however, became a biophysicist through his work with Guayo (Eduardo) Rojas who guided him during his Ph. D thesis in the Laboratorio de Fisiologia Celular in Montemar. His work at N.I.H with Gerald Eherenstein and Harold Lecar constitutes one of the milestones of single ion channel Biophysics. This classical work, done in planar bilayers, set the basis for understanding voltage-dependent conductances with single channel studies and predates, by many years, later studies using patch clamping techniques. Ramon was one of the firsts to find and recognize the importance of calci- activated potassium channels and to begin a detailed study of channel properties. He pioneered the ideas of voltage and calcium modulation of the open probability and he added detailed studies of gating and its modulation by other ions. Ramon is also interested in permeation and selectivity and he produced classical studies on the number of water molecules in the channel and sites occupied by barium. Results and concepts that have recently taken front page as the structure of KcSa has been described.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 53,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Ronald J. Clarke,Mohammed A. A. Khalid
Publisher : John Wiley & Sons
Page : 488 pages
File Size : 50,8 Mb
Release : 2015-10-12
Category : Science
ISBN : 9781118858806

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Pumps, Channels and Transporters by Ronald J. Clarke,Mohammed A. A. Khalid Pdf

Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions

Author : Wilfred D. Stein,Thomas Litman
Publisher : Elsevier
Page : 423 pages
File Size : 40,5 Mb
Release : 2014-12-09
Category : Science
ISBN : 9780124165830

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Channels, Carriers, and Pumps by Wilfred D. Stein,Thomas Litman Pdf

An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Author : Christopher P. Fall,Eric S. Marland,John M. Wagner,John J. Tyson
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 44,6 Mb
Release : 2007-06-04
Category : Science
ISBN : 9780387224596

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Computational Cell Biology by Christopher P. Fall,Eric S. Marland,John M. Wagner,John J. Tyson Pdf

This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.

Author : David Keeling,Chris Benham
Publisher : Elsevier
Page : 413 pages
File Size : 50,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483265667

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Ion Transport by David Keeling,Chris Benham Pdf

Ion Transport is a collection of papers from the Smith Kline & French Research "Symposium on Ion Transport" held in Cambridge, on April 12-14, 1989. These papers focus on the plasma membrane, particularly on the three main classes of transporters, namely, pumps, exchangers, and channels. Some papers discuss the different experimental approaches from electrophysiological and ion flux measurements through pharmacology, molecular biology, electrostatics, and computer modeling. Other papers discuss the P-type cation pump, a class of ATP-driven ion pumps, which is determined from its subunit composition and from the results of the hydrolysis of ATP. Several papers explain the techniques used in ion channels and their modulation. These techniques can be used in the voltage-gated Na+ channel or in permeation mechanisms. Other papers examine the transport proteins involved in the physiology of ion transport. Ions and fluid transport relate to, at the molecular level, how ions cross membranes. A minimum model, in conjunction with theoretical perspective, can describe the mechanism by which ions move through channels. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or biophysics.

Author : Piero P. Foa,Mary F. Walsh
Publisher : Springer Science & Business Media
Page : 605 pages
File Size : 50,9 Mb
Release : 2013-03-07
Category : Science
ISBN : 9781461225966

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Ion Channels and Ion Pumps by Piero P. Foa,Mary F. Walsh Pdf

Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities.

Author : Zuzana Ševčíková Tomášková
Publisher : Unknown
Page : 0 pages
File Size : 44,6 Mb
Release : 2022
Category : Diseases
ISBN : 1803555505

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Ion Transporters by Zuzana Ševčíková Tomášková Pdf

Author : Ron Milo,Rob Phillips
Publisher : Garland Science
Page : 400 pages
File Size : 48,8 Mb
Release : 2015-12-07
Category : Science
ISBN : 9781317230694

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Cell Biology by the Numbers by Ron Milo,Rob Phillips Pdf

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Author : Walter Horst,M.K. Schenk,A. Bürkert,N. Claassen,H. Flessa,W.B. Frommer,Heiner E. Goldbach,H.-W. Olfs,V. Römheld,B. Sattelmacher,U. Schmidhalter,S. Schubert,N. von Wirén,L. Wittenmayer
Publisher : Springer Science & Business Media
Page : 1043 pages
File Size : 54,5 Mb
Release : 2006-05-18
Category : Science
ISBN : 9780306476242

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Plant Nutrition by Walter Horst,M.K. Schenk,A. Bürkert,N. Claassen,H. Flessa,W.B. Frommer,Heiner E. Goldbach,H.-W. Olfs,V. Römheld,B. Sattelmacher,U. Schmidhalter,S. Schubert,N. von Wirén,L. Wittenmayer Pdf

This volume is a compilation of extended abstracts of all papers presented at the 14th International Plant Nutrition Colloquium. Over 500 oral and poster presentations illustrate current knowledge and research emphasis in this subject, providing a comprehensive view of the state of plant nutrition research.

Author : Bertil Hille
Publisher : Sinauer Associates, Incorporated
Page : 632 pages
File Size : 40,9 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015024124383

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Ionic Channels of Excitable Membranes by Bertil Hille Pdf

This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.

Author : Anonim
Publisher : Elsevier
Page : 283 pages
File Size : 47,6 Mb
Release : 1993-05-11
Category : Science
ISBN : 9780080918839

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Molecular Biology of Receptors and Transporters: Pumps, Transporters and Channels by Anonim Pdf

This multi-volume set within International Review of Cytology encompasses the recent advances in the understanding of structure-function relationships at the molecular level of receptors, transporters, and membrane proteins. Several diverse families of membrane receptors/proteins are discussed with respect to the molecular and cellular biology of their synthesis, assembly, turnover, and function. Included are such receptor superfamilies as G-proteins, immunoglobulins, ligand-gated receptors, interleukins, and tyrosine kinases as well as such transporter/protein families as pumps, ion channels, and bacterial transporters. Each section of each volume features a "perspectives/commentary" chapter which includes comments on the recent advances and predictions on new directions. Written by acknowledged experts in the field, this volume, 137C, highlights recent developments in pumps, channels, and transporters. Key Features * The latest on several important protein families, including: * The G-protein-coupled receptors * The interleukin receptors * Sugar transporters * Several ion channels and pumps

Author : Irwin B. Levitan,Leonard K. Kaczmarek
Publisher : Oxford University Press, USA
Page : 640 pages
File Size : 42,9 Mb
Release : 2002
Category : Molecular neurobiology
ISBN : 0195145232

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The Neuron by Irwin B. Levitan,Leonard K. Kaczmarek Pdf

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Author : Armin Kargol
Publisher : Morgan & Claypool Publishers
Page : 117 pages
File Size : 41,5 Mb
Release : 2019-03-29
Category : Science
ISBN : 9781643274102

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Introduction to Cellular Biophysics, Volume 1 by Armin Kargol Pdf

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Author : Anonim
Publisher : Academic Press
Page : 307 pages
File Size : 54,7 Mb
Release : 2013-07-24
Category : Science
ISBN : 9780124079380

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Store-Operated Calcium Channels by Anonim Pdf

Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels Contributors are authoritative researchers who have produced important advances in the field The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject