Pyrroles Part 1

Author : Richard A. Jones
Publisher : John Wiley & Sons
Page : 765 pages
File Size : 51,9 Mb
Release : 2009-09-17
Category : Science
ISBN : 9780470188842

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Pyrroles, Volume 48, Part 1 by Richard A. Jones Pdf

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Author : Richard A. Jones
Publisher : Wiley-Interscience
Page : 742 pages
File Size : 44,7 Mb
Release : 1990-04-12
Category : Science
ISBN : 0471627534

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Pyrroles, Part 1 by Richard A. Jones Pdf

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Author : R. Alan Jones,Gerritt P. Bean
Publisher : Academic Press
Page : 539 pages
File Size : 48,5 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218472

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The Chemistry of Pyrroles by R. Alan Jones,Gerritt P. Bean Pdf

The Chemistry of Pyrroles, Volume 34 aims to provide a comprehensive survey of the synthesis of simple pyrroles and to present, wherever possible, a mechanistic and theoretical rationale for the multitude of reactions known for pyrroles. The book discusses the structure and reactivity of pyrrole; the synthesis of the pyrrole ring; and the electrophilic substitution of the pyrrole ring. The text also describes the oxidation and reduction of the pyrrole ring; the rearrangement and addition reactions; and the ketones, aldehydes, and carboxylic acid derivatives of pyrrole. Alkylpyrroles and related compounds; hydroxy- and aminopyrroles and related compounds; and azafulvenes are also considered. The book further tackles the physico-organic properties of pyrrole. Chemists and researchers of pyrrole chemistry will find the text invaluable.

Author : Richard A. Jones
Publisher : John Wiley & Sons
Page : 647 pages
File Size : 41,6 Mb
Release : 2009-09-17
Category : Science
ISBN : 9780470188866

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Pyrroles, Volume 48, Part 2 by Richard A. Jones Pdf

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Author : Boris A. Trofimov,Al'bina I. Mikhaleva,Elena Yu Schmidt,Lyubov N. Sobenina
Publisher : CRC Press
Page : 402 pages
File Size : 48,9 Mb
Release : 2014-10-13
Category : Science
ISBN : 9781482232424

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Chemistry of Pyrroles by Boris A. Trofimov,Al'bina I. Mikhaleva,Elena Yu Schmidt,Lyubov N. Sobenina Pdf

During the last 30 years, knowledge of the essential role that pyrrole structures play in the chemistry of living organisms, drug design, and the development of advanced materials has increased. Correspondingly, research on the diverse issues of synthetic, theoretical, and applied chemistry has snowballed. Devoted to the latest achievements of this field, Chemistry of Pyrroles covers the discovery and development of a novel, facile, and highly effective method for the construction of the pyrrole ring from ketones (ketoximes) and acetylene in superbase catalytic systems (Trofimov reaction). It provides cutting-edge details on the preparation of valuable but previously inaccessible pyrrole compounds. It includes approximately 1,000 structures of novel pyrrole compounds, their yields, and physical-chemical characteristics. The authors analyze conditions of typical syntheses, limitations of their applicability, and possibility of vinyl chloride or dichloroethane application instead of acetylene. They examine chemical engineering aspects of the first synthesis of tetrahydroindole and indole from commercially available oxime of cyclohexanone and acetylene. In addition, the book discusses new facets of pyrroles and N-vinyl pyrroles reactivity in the reactions with the participation of both the pyrrole ring and N-vinyl groups. The book provides condensed, clear-cut information on novel syntheses of substituted pyrroles as key structural units of living matter (chlorophyll and hemoglobin), pharmaceuticals, and monomers for optoelectronic materials. It includes tables that provide references to original works, forming a guide to a variety of the reactions and synthesized compounds discussed. With coverage of the broad range of pyrrole chemistry and methods for their synthesis, it provides both a theoretical and an experimental basis for drug design.

Author : Alan R. Katritzky
Publisher : Elsevier
Page : 568 pages
File Size : 55,6 Mb
Release : 2017-01-31
Category : Science
ISBN : 9781483293424

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Handbook of Heterocyclic Chemistry by Alan R. Katritzky Pdf

Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

Author : Richard A. Jones
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 51,8 Mb
Release : 1991-01-16
Category : Science
ISBN : 0471627534

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Pyrroles, Volume 48, Part 1 by Richard A. Jones Pdf

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Author : Krishna C. Majumdar,Shital K. Chattopadhyay
Publisher : John Wiley & Sons
Page : 648 pages
File Size : 46,9 Mb
Release : 2011-06-15
Category : Science
ISBN : 9783527634897

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Heterocycles in Natural Product Synthesis by Krishna C. Majumdar,Shital K. Chattopadhyay Pdf

Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.

Author : Isaac Ishaaya,Danny Degheele
Publisher : Springer Science & Business Media
Page : 442 pages
File Size : 52,5 Mb
Release : 2013-06-29
Category : Technology & Engineering
ISBN : 9783662035658

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Insecticides with Novel Modes of Action by Isaac Ishaaya,Danny Degheele Pdf

The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 642 pages
File Size : 45,8 Mb
Release : 2021-02-26
Category : Science
ISBN : 9780128205860

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Green Synthetic Approaches for Biologically Relevant Heterocycles by Goutam Brahmachari Pdf

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Author : Manfred Schlosser
Publisher : John Wiley & Sons
Page : 1008 pages
File Size : 55,5 Mb
Release : 2013-05-28
Category : Science
ISBN : 9781118484753

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Organometallics in Synthesis by Manfred Schlosser Pdf

WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.

Author : David St. Clair Black,Janine Cossy,Christian V. Stevens
Publisher : Unknown
Page : 0 pages
File Size : 54,8 Mb
Release : 2022
Category : Heterocyclic chemistry
ISBN : 0323912672

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Comprehensive Heterocyclic Chemistry IV by David St. Clair Black,Janine Cossy,Christian V. Stevens Pdf

Author : Marcel Florkin,Elmer H. Stotz
Publisher : Elsevier
Page : 285 pages
File Size : 52,5 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483222219

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Pyrrole Pigments, Isoprenoid Compounds and Phenolic Plant Constituents by Marcel Florkin,Elmer H. Stotz Pdf

Comprehensive Biochemisty, Volume 9: Pyrrole Pigments, Isoprenoid Compounds and Phenolic Plant Constituents focuses on the organic and physical chemistry of the major organic constituents of living material. This book discusses the correlations between structure and visible spectrum, theoretical interpretation of the visible absorption spectra, and spectrophotometric determination of chlorophyll. The quantitative aspects of hemoglobin breakdown, monocyclic and bicyclic carbon systems, and substances related to retinol are also elaborated. This publication likewise covers the naturally occurring quinones, phenolic compounds derived by linear condensation of two-carbon units, and single-carbon incorporation into ring systems. This volume is useful to biochemists and specialists researching on pyrrole pigments, isoprenoid compounds, and phenolic plant constituents.

Author : Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap
Publisher : Elsevier
Page : 500 pages
File Size : 45,7 Mb
Release : 2019-06-05
Category : Science
ISBN : 9780081011911

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The Chemistry of Heterocycles by Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap Pdf

Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make life possible. The Chemistry of Heterocycles covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N,O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N,O,S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described. Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N,O and,S containing heterocycles

Author : Yusuke Kawamoto
Publisher : Springer
Page : 122 pages
File Size : 42,5 Mb
Release : 2019-03-07
Category : Science
ISBN : 9789811369124

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Synthesis and Biological Evaluation of Pyrrole–Imidazole Polyamide Probes for Visualization of Telomeres by Yusuke Kawamoto Pdf

This book presents a novel method of synthesizing sequence-specific DNA binding pyrrole–imidazole (Py–Im) polyamides and demonstrates polyamides targeting longer base pairs than those previously reported and their cellular application. It discusses the development of the facile synthetic method of tandem hairpin Py–Im polyamides and the method of visualizing telomeres under mild conditions without harsh denaturation, as well as research resulting in the synthesis not only of previously reported tandem dimer polyamides but also longer tandem trimer and tetramer polyamides. Using fluorescently labeled tandem hairpin Py–Im polyamides targeting a human telomere repetitive sequence, the author successfully stained telomeres in fixed cells without denaturation. These fluorescently labeled tandem tetramer polyamides are able to visualize human telomeres with lower background signals than previous polyamide probes, suggesting that they have higher specificity for telomeres. As such, this book provides insights into recent advance in Py–Im polyamides, particularly the extension of the target sites c